公开(公告)号：US20110092229A1

公开(公告)日：2011-04-21

申请号：US12603304

申请日：2009-10-21

Applicant: Li Fung Chang ,  Bin Liu

Inventor： Li Fung Chang ,  Bin Liu

IPC: H04W68/00

CPC classification number: H04W76/10 ,  H04L1/0038 ,  H04L1/005 ,  H04L1/0061 ,  H04L1/1819 ,  H04L1/1845 ,  H04W28/18 ,  H04W68/00

Abstract: A UE in an URA_PCH state or a Cell_PCH state receives a HS-PDSCH without an associated HS-SCCH. No dedicated H-RNTI is assigned to the UE. The received HS-PDSCH is separately processed using one or more different predetermined transport format. The different predetermined transport formats are identified from associated HS-DSCH paging system information block. The UE starts blindly processing the received HS-PDSCH by determining a set of configuration parameters according to a first transport format of the identified predetermined transport formats. One or more associated device components such as hardware components of the UE are configured using the determined set of configuration parameters. The configured device components are used to perform HARQ processing, IR combining and/or Turbo decoding on the received HS_PDSCH without associated HS_SCCH. The UE continuously processes the received HS-PDSCH using the next available predetermined transport format when a CRC test completes with an error.

Abstract translation: 在URA_PCH状态或Cell_PCH状态的UE接收没有相关联的HS-SCCH的HS-PDSCH。 没有专用的H-RNTI被分配给UE。 使用一种或多种不同的预定传输格式分别处理所接收的HS-PDSCH。 从相关联的HS-DSCH寻呼系统信息块识别不同的预定传输格式。 UE通过根据所识别的预定传输格式的第一传输格式确定一组配置参数来开始盲接处理所接收的HS-PDSCH。 使用所确定的一组配置参数来配置一个或多个关联设备组件，例如UE的硬件组件。 配置的设备组件用于对所接收的HS_PDSCH进行HARQ处理，IR组合和/或Turbo解码，而不关联HS_SCCH。 当CRC测试完成时，UE使用下一个可用的预定传输格式连续处理接收的HS-PDSCH。

公开(公告)号：US20110085493A1

公开(公告)日：2011-04-14

申请号：US12577080

申请日：2009-10-09

Applicant: Li Fung Chang ,  Khoi Ly ,  Bin Liu ,  Simon Baker

Inventor： Li Fung Chang ,  Khoi Ly ,  Bin Liu ,  Simon Baker

IPC: H04W40/00

CPC classification number: H04L1/0038 ,  H04L1/0046 ,  H04L1/0061 ,  H04L1/1835 ,  H04W28/04 ,  H04W28/14 ,  H04W88/06

Abstract: A UE receives HSDPA traffic comprising legacy HSDPA traffic and HS-SCCH-less HSDPA traffic. The UE concurrently processes the received legacy HSDPA traffic and the received HS-SCCH-less HSDPA traffic. The received HSDPA traffic is concurrently buffered into a first storage and a second storage to support simultaneously receiving legacy HSDPA traffic and HS-SCCH-less HSDPA traffic. A HARQ process is performed on the buffered HSDPA traffic in the first storage or the second storage according to a corresponding HS-SCCH CRC test. The resulting HARQ processed HSDPA traffic is Turbo decoded. Turbo decoding on the previously HARQ processed HSDPA traffic is performed simultaneously with HARQ processing on the buffered HSDPA traffic in the first storage or the second storage. The buffered HS-SCCH-less HSDPA traffic is processed via HARQ processing and Turbo decoding for each of the four pre-determined transport formats.

Abstract translation: UE接收包括传统HSDPA业务和HS-SCCH-HSDPA业务的HSDPA业务。 UE同时处理接收到的传统HSDPA业务和所接收的HS-SCCH-HSDPA业务。 所接收的HSDPA业务被同时缓存到第一存储器和第二存储器中，以支持同时接收传统HSDPA业务和HS-SCCH-less HSDPA业务。 根据相应的HS-SCCH CRC测试，在第一存储器或第二存储器中对缓冲的HSDPA业务执行HARQ过程。 所产生的HARQ处理的HSDPA业务被Turbo解码。 对先前HARQ处理的HSDPA业务的Turbo解码与对第一存储器或第二存储器中的缓冲HSDPA业务的HARQ处理同时进行。 通过针对四种预定传输格式中的每一种的HARQ处理和Turbo解码来处理缓冲的无HS-SCCH的HSDPA业务。

公开(公告)号：US20110075708A1

公开(公告)日：2011-03-31

申请号：US12575879

申请日：2009-10-08

Applicant: Mark Hahm ,  Wei Luo ,  Bin Liu ,  Jun Wu ,  Severine Catreux-Erceg ,  Shuangquan Wang

Inventor： Mark Hahm ,  Wei Luo ,  Bin Liu ,  Jun Wu ,  Severine Catreux-Erceg ,  Shuangquan Wang

IPC: H04L1/02 ,  H04B1/707

CPC classification number: H04B1/711 ,  H04B1/71072 ,  H04B1/712 ,  H04J13/0044

Abstract: A wireless system may receive a plurality of multipath signals from a plurality of transmitters and allocate per-cell modules for generating an interference suppressed signal from the multipath signals. Data symbols may be sequentially processed in the received multipath signals utilizing the per-cell modules and subtracting the processed symbols from a residual buffer storing the received multipath signals. Desired information received from one or more of the transmitters may be recovered utilizing the interference suppressed signal. Timing of the data symbols may be correlated utilizing a cell chip combiner. The data symbols may be descrambled utilizing conjugated scrambling codes associated with one of the plurality of transmitters. Orthogonal variable spreading factor (OVSF) codes may be generated utilizing a Walsh transform on the data symbols. Power levels of the OVSF codes may be estimated and estimated signals may be generated based on the OVSF codes and the estimated power levels.

Abstract translation: 无线系统可以从多个发射机接收多个多径信号，并且分配用于从多路径信号产生干扰抑制信号的每小区模块。 数据符号可以利用每个单元模块在所接收的多路径信号中被顺序地处理，并且从存储所接收的多径信号的残差缓冲器中减去经处理的符号。 可以使用干扰抑制信号来恢复从一个或多个发射机接收到的期望信息。 数据符号的定时可以利用单元芯片组合器进行相关。 数据符号可以利用与多个发射机之一相关联的共轭扰码进行解扰。 可以使用对数据符号的沃尔什变换来生成正交可变扩展因子（OVSF）码。 可以估计OVSF码的功率电平，并且可以基于OVSF码和估计功率电平来生成估计信号。

公开(公告)号：US07897684B2

公开(公告)日：2011-03-01

申请号：US11329495

申请日：2006-01-10

Applicant: Guillermo C. Bazan ,  Bin Liu

Inventor： Guillermo C. Bazan ,  Bin Liu

IPC: C08G63/91 ,  C08G63/00 ,  C12Q1/68

CPC classification number: C08G61/02 ,  C08G61/122 ,  C08G61/123 ,  C12Q1/6818 ,  C12Q1/6837 ,  G01N21/6428 ,  G01N21/6452 ,  G01N2021/6419 ,  G01N2021/6439 ,  C12Q2563/131 ,  C12Q2537/119 ,  C12Q2525/107

Abstract: The invention further relates to polycationic multichromophores, which may be conjugated polymers, and methods, articles and compositions employing them as described herein. In some aspects, the invention relates to methods, articles and compositions for the detection and analysis of biomolecules in a sample. Provided assays include those determining the presence of a target biomolecule in a sample or its relative amount, or the assays may be quantitative or semi-quantitative. The methods can be performed on a substrate. The methods can be performed in an array format on a substrate, which can be a sensor. In some embodiments, detection assays are provided employing sensor biomolecules that do not comprise a fluorophore that can exchange energy with the cationic multichromophore. In some aspects biological assays are provided in which energy is transferred between one or more of the multichromophore, a label on the target biomolecule, a label on the sensor biomolecule, and/or a fluorescent dye specific for a polynucleotide, in all permutations. The multichromophore may interact at least in part electrostatically with the sensor and/or the target, and an increase in energy transfer with the polymer may occur upon binding of the sensor and the target. Other variations of the inventions are described further herein.

Abstract translation: 本发明还涉及可以是共轭聚合物的阳离子多色素，以及如本文所述使用它们的方法，制品和组合物。 在一些方面，本发明涉及用于检测和分析样品中生物分子的方法，制品和组合物。 提供的测定包括确定样品中靶生物分子的存在或其相对量的那些，或者测定可以是定量或半定量的。 该方法可以在衬底上进行。 这些方法可以以阵列格式在基底上进行，其可以是传感器。 在一些实施方案中，使用不包含能够与阳离子多重色素交换能量的荧光团的传感器生物分子来提供检测测定。 在一些方面，提供生物测定，其中在所有置换中，能量在一个或多个多色素，目标生物分子上的标记，传感器生物分子上的标记和/或多核苷酸特异的荧光染料之间转移。 多重色淀可以至少部分地与传感器和/或靶相互作用，并且当传感器和目标物结合时，聚合物的能量传递的增加可能发生。 本文进一步描述了本发明的其它变型。

公开(公告)号：US07786145B2

公开(公告)日：2010-08-31

申请号：US10900706

申请日：2004-07-28

Applicant: Jie Fei Cheng ,  Bin Liu ,  Thomas Arrhenius ,  Mark E. Wilson ,  Alex M. Nadzan ,  Gary D. Lopaschuk ,  Jason R. Dyck ,  Rossy Serafimov

Inventor： Jie Fei Cheng ,  Bin Liu ,  Thomas Arrhenius ,  Mark E. Wilson ,  Alex M. Nadzan ,  Gary D. Lopaschuk ,  Jason R. Dyck ,  Rossy Serafimov

IPC: A61K31/4406 ,  A61K31/428 ,  A61K31/4025 ,  C07D417/12 ,  C07D277/72 ,  C07D207/14

CPC classification number: C07D277/70 ,  A61K31/428 ,  A61K31/4439 ,  A61K31/4745 ,  A61K31/506 ,  C07D417/12

Abstract: The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.

Abstract translation: 本发明提供了使用结构I所示化合物的方法，含有该化合物的药物组合物，以及预防，治疗和治疗由MCD抑制调节的代谢疾病和疾病的方法。 本发明公开的化合物可用于预防，管理和治疗涉及丙二酰辅酶A调节的葡萄糖/脂肪酸代谢途径的疾病。 特别地，这些化合物和含有它们的药物组合物在心血管疾病，糖尿病，癌症和肥胖症的预防，治疗和治疗中被指出。

公开(公告)号：US20100003267A1

公开(公告)日：2010-01-07

申请号：US12432528

申请日：2009-04-29

Applicant: Venkata Ramana Doppalapudi ,  Jing-Yu Lai ,  Bin Liu ,  Dingguo Liu ,  Joel Desharnais ,  Abhijit Suresh Bhat ,  Yanwen Fu ,  Bryan Douglas Oates ,  Gang Chen ,  Curt William Bradshaw

Inventor： Venkata Ramana Doppalapudi ,  Jing-Yu Lai ,  Bin Liu ,  Dingguo Liu ,  Joel Desharnais ,  Abhijit Suresh Bhat ,  Yanwen Fu ,  Bryan Douglas Oates ,  Gang Chen ,  Curt William Bradshaw

IPC: A61K39/395 ,  C07K14/00 ,  C07K19/00

CPC classification number: A61K47/48215 ,  A61K47/48246 ,  A61K47/48415 ,  A61K47/48507 ,  A61K47/60 ,  A61K47/64 ,  A61K47/6811 ,  A61K47/6835 ,  C07K14/71

Abstract: The present invention provides VEGF binding peptides. In addition, the invention provides VEGF peptides conjugated to antibodies alone and in conjunction with other anti-angiogenic molecules. Various uses of the peptides and compounds are provided, including methods to treat disorders associated with abnormal angiogenesis.

Abstract translation: 本发明提供VEGF结合肽。 此外，本发明提供了与单独的抗体和其它抗血管生成分子结合的VEGF肽。 提供肽和化合物的各种用途，包括治疗与异常血管发生相关的疾病的方法。

公开(公告)号：US07601356B2

公开(公告)日：2009-10-13

申请号：US11780627

申请日：2007-07-20

Applicant: Hong Jin ,  Bin Liu

Inventor： Hong Jin ,  Bin Liu

IPC: A61K39/145 ,  C12N7/04 ,  C12N15/44

CPC classification number: C12N7/00 ,  A61K39/12 ,  A61K39/145 ,  C07K14/005 ,  C12N2760/16121 ,  C12N2760/16122 ,  C12N2760/16134

Abstract: In certain aspects, the present invention provides methods for increasing the replication capacity of influenza viruses in hens' eggs and/or cell culture, recombinant and/or reassortant influenza viruses with increased replication capacity, and immunogenic and vaccine compositions comprising such recombinant and/or reassortant influenza viruses. In other aspects, the invention further provides nucleic acids encoding influenza genes associated with increased replication capacity, expression vectors comprising the nucleic acids of the invention, methods for making influenza viruses with increased replication capacity, and kits useful for practice of the methods.

Abstract translation: 在某些方面，本发明提供了增加在具有增加的复制能力的母鸡卵和/或细胞培养物，重组和/或重配流感病毒中的流感病毒的复制能力的方法，以及包含这种重组和/或 重配流感病毒。 在其它方面，本发明还提供编码与增加的复制能力相关的流感基因的核酸，包含本发明的核酸的表达载体，具有增加的复制能力的制备流感病毒的方法，以及可用于实施该方法的试剂盒。

公开(公告)号：US07582736B2

公开(公告)日：2009-09-01

申请号：US11972130

申请日：2008-01-10

Applicant: Bin Liu ,  James D. Marks

Inventor： Bin Liu ,  James D. Marks

IPC: C12P21/08

CPC classification number: C07K16/3069 ,  A61K2039/505 ,  C07K2317/622 ,  C07K2317/73 ,  C07K2317/77

Abstract: This invention provides novel prostate cancer specific internalizing human antibodies. The antibodies are useful by themselves to prevent growth and/or proliferation of prostate cancer cells. The antibodies can also be formulated as chimeric molecules to direct an effector (e.g. a cytotoxin, an imaging reagent, a drug, etc.) to a prostate tumor site.

Abstract translation: 本发明提供了新型前列腺癌特异性内化人抗体。 抗体本身可用于预防前列腺癌细胞的生长和/或增殖。 抗体还可以配制成嵌合分子以将效应物（例如细胞毒素，成像试剂，药物等）引导至前列腺肿瘤部位。

公开(公告)号：US20080280891A1

公开(公告)日：2008-11-13

申请号：US11819494

申请日：2007-06-27

Applicant: Martha Kelly ,  Younghee Lee ,  Bin Liu ,  Ted Fujimoto ,  Joel Freundlich ,  Bruce D. Dorsey ,  Gary A. Flynn ,  Arifa Husain ,  William R. Moore, Jr.

Inventor： Martha Kelly ,  Younghee Lee ,  Bin Liu ,  Ted Fujimoto ,  Joel Freundlich ,  Bruce D. Dorsey ,  Gary A. Flynn ,  Arifa Husain ,  William R. Moore, Jr.

IPC: A61K31/541 ,  A61K31/404 ,  C07D209/42 ,  C07D401/02 ,  C07D417/14 ,  A61K31/44 ,  A61P35/00 ,  A61K31/4439 ,  A61K31/5377 ,  C07D413/14

CPC classification number: A61K31/404 ,  A61K31/44 ,  A61K31/4439 ,  A61K31/5377 ,  A61K31/541 ,  C07D213/74 ,  C07D231/56 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D409/10 ,  C07D413/12 ,  C07D498/04

Abstract: The present invention is in the area of novel compounds and salts thereof, their syntheses, and their use as anti-cancer agents. The compounds include compounds of Formula I: and solvates, hydrates and pharmaceutically-acceptable salts thereof, wherein A1 is N or CR1; A3 is N or CR3; A5 is N or CR5; R1, R3-R6 and L are defined in the specification; n is 0 or 1; and X is an optionally-substituted aryl group having 6-10 carbons in the ring portion, an optionally-substituted 6-membered heteroaryl group having 1-3 nitrogen atoms in the ring portion, an optionally-substituted 5-membered heteroaryl group having 0-4 nitrogen atoms in the ring portion and optionally having 1 sulfur atom or 1 oxygen atom in the ring portion, or an optionally-substituted heteroaryl group in which a 6-membered ring is fused either to a 5-membered ring or to a 6-membered ring, wherein in each case 1, 2, 3 or 4 ring atoms are heteroatoms independently selected from nitrogen, oxygen and sulfur. They are effective against a broad range of cancers, especially leukemia, prostate, non-small cell lung and colon. They are additionally useful in the treatment of proliferative retinopathies such as diabetic neuropathy and macular degeneration.

Abstract translation: 本发明涉及新型化合物及其盐，其合成及其作为抗癌剂的用途。 化合物包括式I化合物及其溶剂合物，水合物及其药学上可接受的盐，其中A 1是N或CR 1; N 3或N 3是N或CR 3; A <5>为N或CR 5; 在说明书中定义了R 1，R 3，R 6和L 6; n为0或1; 并且X是在环部分中具有6-10个碳的任选取代的芳基，在环部分中具有1-3个氮原子的任选取代的6元杂芳基，任选取代的5元杂芳基具有0 -4个氮原子，并且在环部分中任选具有1个硫原子或1个氧原子，或任选取代的杂芳基，其中6元环稠合到5元环或6元环 其中在每种情况下，1,2,3或4个环原子是独立地选自氮，氧和硫的杂原子。 它们对广泛的癌症尤其是白血病，前列腺，非小细胞肺和结肠有效。 它们还可用于治疗增殖性视网膜病变，例如糖尿病性神经病变和黄斑变性。

公开(公告)号：US07356594B2

公开(公告)日：2008-04-08

申请号：US10678976

申请日：2003-10-03

Applicant: Charbel Khawand ,  Jianping W. Miller ,  Jean Khawand ,  Bin Liu

Inventor： Charbel Khawand ,  Jianping W. Miller ,  Jean Khawand ,  Bin Liu

IPC: G06F15/173 ,  G06F13/00

CPC classification number: H04L67/14 ,  H04L69/329

Abstract: An IPC protocol/network allows for intelligent targeting of nodes in order to reduce overhead and provide for improved power management. The IPC server keeps track of the IPC network's node activity and using an operational state table (2000) it can determine which node can handle a service request (e.g., MP3 decode). By keeping track of the current operational condition of the nodes within the network, the processors can have better battery life and application latency can be improved. The IPC server will keep track not only of which nodes can handle which services, but it will also know which node can handle the service request given its knowledge of the operational state of each of the nodes.

Abstract translation: IPC协议/网络允许节点的智能目标，以减少开销并提供改进的电源管理。 IPC服务器跟踪IPC网络的节点活动并使用操作状态表（2000），它可以确定哪个节点可以处理服务请求（例如，MP3解码）。 通过跟踪网络中节点的当前操作条件，处理器可以具有更好的电池寿命并且可以提高应用延迟。 IPC服务器不仅将跟踪哪些节点可以处理哪些服务，而且还将知道哪个节点可以处理服务请求，因为它知道每个节点的操作状态。