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141.
公开(公告)号:US11974800B2
公开(公告)日:2024-05-07
申请号:US16747219
申请日:2020-01-20
Applicant: Virginia Tech Intellectual Properties, Inc.
Inventor: Michael B. Sano , Rafael V. Davalos , John L Robertson , Paulo A. Garcia , Robert E. Neal
CPC classification number: A61B18/14 , A61K48/0075 , A61M5/00 , A61B2018/00613 , A61B2018/1472 , A61B18/1492 , A61B2218/002 , A61N1/327
Abstract: The present invention relates to the field of medical treatment of diseases and disorders, as well as the field of biomedical engineering. Embodiments of the invention relate to the delivery of Irreversible Electroporation (IRE) through the vasculature of organs to treat tumors embedded deep within the tissue or organ, or to decellularize organs to produce a scaffold from existing animal tissue with the existing vasculature intact. In particular, methods of administering non-thermal irreversible electroporation (IRE) in vivo are provided for the treatment of tumors located in vascularized tissues and organs. Embodiments of the invention further provide scaffolds and tissues from natural sources created using IRE ex vivo to remove cellular debris, maximize recellularization potential, and minimize foreign body immune response. The engineered tissues can be used in methods of treating subjects, such as those in need of tissue replacement or augmentation.
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公开(公告)号:US11972896B2
公开(公告)日:2024-04-30
申请号:US17025777
申请日:2020-09-18
Applicant: Virginia Tech Intellectual Properties, Inc.
Inventor: Khai Doan The Ngo , Han Cui
CPC classification number: H01F3/10 , H01F27/255 , H01F27/2823 , H01F37/00 , H01F41/04 , H01F41/041 , Y10T29/4902
Abstract: The present invention is directed to a compact inductor having the required (predetermined) inductance and current rating, further designed to avoid substantial heat generation by avoiding saturation, winding(s) possessing a low DC resistance and copper loss, and minimizing the required volume or profile in order to conserve circuit board real-estate. The compact inductor design of the present invention includes both enclosed core as well as enclosed winding type of inductor designs.
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公开(公告)号:US11966816B2
公开(公告)日:2024-04-23
申请号:US17765875
申请日:2020-10-02
Applicant: VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.
Inventor: Edwin Barnes , Junkai Zeng
Abstract: Aspects of generating error-resistant quantum control pulses from geometrical curves are described. In some embodiments, a closed space curve is parameterized for a target gate operation of a quantum computing device. The closed space curve corresponds to an evolution operator of a time-dependent Schrödinger equation associated with the target gate operation. A control field definition is identified for the target gate operation based at least in part on a geometrical analysis of the evolution operator of the time-dependent Schrödinger equation. The target gate operation is implemented for the quantum computing device based on the control field definition.
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144.
公开(公告)号:US11947163B2
公开(公告)日:2024-04-02
申请号:US16893281
申请日:2020-06-04
Applicant: Virginia Tech Intellectual Properties, Inc.
Inventor: Xiaoting Jia , Anbo Wang , Haifeng Xuan , Li Yu
IPC: G02B6/10 , D01D5/00 , D01D5/084 , D01D5/098 , D01D5/34 , D02G3/44 , D03D1/00 , D06M11/00 , D06M15/00 , H01B3/00 , H01B3/02 , H01B3/08 , H01B3/12 , H01B3/30 , H01B7/04 , H01B19/04 , G01L9/00 , G02B6/12
CPC classification number: G02B6/10 , D01D5/0023 , D01D5/084 , D01D5/098 , D01D5/34 , D02G3/441 , D03D1/0088 , D06M11/00 , D06M15/00 , H01B3/00 , H01B3/02 , H01B3/082 , H01B3/12 , H01B3/30 , H01B7/04 , H01B19/04 , D10B2101/20 , D10B2401/16 , D10B2401/18 , G01L9/0002 , G02B2006/12069 , G02B2006/12111 , G02B2006/12166
Abstract: In one aspect, the disclosure relates to multi-material fibers capable of distributedly measuring temperature and pressure in which the methods comprise a thermal drawing step, and the methods of fabricating the disclosed fibers. The fibers can be utilized in methods of temperature and pressure mapping or sensing comprising electrical reflectometry for interrogation. Further disclosed are devices comprising a disclosed fiber with the multi-point detection capability with simple one-end connection. Also disclosed are articles, e.g., smart clothing, wound dressing, robotic skin and other industrial products, comprising a disclosed fiber or a fabric comprising a disclosed fiber. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
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公开(公告)号:US20240097572A1
公开(公告)日:2024-03-21
申请号:US17932399
申请日:2022-09-15
Applicant: VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.
Inventor: Yuliang Cao , Yijie Bai , Vladimir Mitrovic , Boran Fan , Dong Dong , Rolando Burgos
CPC classification number: H02M3/33573 , H02M1/08
Abstract: Power systems including converters that exhibit reduced common mode voltage emissions are described. In one example, a power converter system includes an input and an output, a multi-level switch bridge coupled between the input and the output, an input capacitor branch coupled across the input, an output capacitor branch coupled across the output, and a controller configured to generate switching control signals for the multi-level buck-boost switch bridge. The multi-level switch bridge also includes a plurality of inductors in one example. In one case, a quadrangular or quadrangle control mode can be relied upon to switch the multi-level switch bridge, to minimize the ripple in the inductors, achieve zero voltage switching, reduce common mode electromagnetic interference emission by the converter, and for other benefits.
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公开(公告)号:US20240079484A1
公开(公告)日:2024-03-07
申请号:US17939373
申请日:2022-09-07
Applicant: Virginia Tech Intellectual Properties, Inc.
Inventor: Yuhao ZHANG , Ming XIAO
IPC: H01L29/778 , H01L27/06 , H01L27/088 , H01L29/20
CPC classification number: H01L29/7786 , H01L27/0605 , H01L27/0883 , H01L29/2003
Abstract: This disclosure provides semiconductor device including a first transistor with a first gate terminal, a first source terminal, and the first drain terminal, the first transistor being a depletion mode transistor and including a plurality of two-dimensional carrier channels of a conductivity type being one of a n-type or a p-type conductivity. The semiconductor device also includes a second transistor with a second gate terminal, a second source terminal, and a second drain terminal, the second transistor being an enhancement mode transistor, a gate-source interconnect forming an electrical connection between the first gate terminal and the second source terminal, and a drain-source interconnect forming an electrical connection between the first source terminal and the second drain terminal. The first transistor and the second transistor are fabricated on the same wafer or substrate.
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147.
公开(公告)号:US11914954B2
公开(公告)日:2024-02-27
申请号:US17113880
申请日:2020-12-07
Applicant: VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.
Inventor: Edward A. Fox , Saurabh Chakravarty , Raja Venkata Satya Phanindra Chava , Maanav Mehrotra
IPC: G06F40/205 , G06F40/279 , G06N3/044 , G06N20/00 , G06Q30/018 , G06Q50/26
CPC classification number: G06F40/205 , G06F40/279 , G06N3/044 , G06N20/00 , G06Q30/018 , G06Q50/265
Abstract: Described herein are systems and methods to enable generation of high-quality summaries of documents that have questions and answers. To help summarize such documents, parsing methods are disclosed that account for different document formats. Methods are disclosed to anonymize personal and identifying information present in the documents. An ontology is defined to categorize dialog acts for the questions and answers present. Classifiers are disclosed based on this ontology. Methods are also disclosed to transform a question-answer pair to a canonical form. Based on the dialog acts for the question and answer combination, transformation methods were developed that build upon each of traditional NLP, and deep learning, techniques.
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公开(公告)号:US11912819B2
公开(公告)日:2024-02-27
申请号:US17284717
申请日:2019-11-13
Inventor: Monica Lotz , Kapil Kandel , Michael Salciccioli , Stephen Cohn , Alan A. Galuska , Javier Guzman , S. Richard Turner , Hans Eliot Edling , Edward E. Paschke
IPC: C08G63/185 , C08G63/199 , C08G63/80 , C08G63/85
CPC classification number: C08G63/185 , C08G63/199 , C08G63/80 , C08G63/85 , C08G2120/00 , C08G2250/00
Abstract: Semicrystalline polyethylene-2,2′-bifuran-5,5′-dicarboxylate (PEBF) homopolyester or copolyester with up to 5 mole percent isophthalate or up to 2.7 mole percent terephthalate, based on the diacid component, or up to 2.5 mole percent 1,4-cyclohexanedimethanol (CHDM), based on the diol component, prepared by esterifying or transesterifying the diacid and the diol components with a catalyst including about 10 to about 50 ppm wt metal, and polycondensation, wherein the bifuran polyester has an intrinsic viscosity of at least 0.4 g/dL and a semicrystalline melting peak (Tm) with ΔHf equal to or greater than 5 J/g on the second heating ramp.
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公开(公告)号:US20240053415A1
公开(公告)日:2024-02-15
申请号:US18332248
申请日:2023-06-09
Applicant: VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.
Inventor: Zachary Daniel Hileman , Daniel Homa , Gary Pickrell , Eileen Martin
IPC: G01R33/09
CPC classification number: G01R33/091
Abstract: A magnetic field sensor in the form of a multi-material optical fiber is described. The magnetic sensing optical fiber of the present disclosure can leverage optics and magnetostriction to sense an external magnetic field adjacent to the fiber. The magnetic sensing optical fiber can be customized to achieve various desired sensing sensitivities for various applications, including measuring while drilling and unconventional oil and gas applications. In one example, an optical fiber can include a cladding that can extend from a first end to a second end of the optical fiber. The optical fiber can further include an optical core within the cladding. The optical core can extend along the optical fiber between the first end and the second end. The optical fiber can also include a magnetostrictive element within the cladding. The magnetostrictive element can extend along the optical fiber between the first end and the second end.
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150.
公开(公告)号:US11894778B2
公开(公告)日:2024-02-06
申请号:US17511753
申请日:2021-10-27
Applicant: VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.
Inventor: Xin Lou , Qiang Li , Fred C. Lee
IPC: H02M3/335
CPC classification number: H02M3/33592
Abstract: Aspects of direct current (DC)-DC converters with an integrated matrix transformer and multiphase current doubler rectifiers are described. In some examples, a DC-DC converter can include a matrix transformer that has multiple magnetically integrated transformer components that are magnetically integrated using transformer components that share a top plate and a bottom plate. A multiphase current doubler rectifier can include multiple synchronous rectifiers corresponding to the plurality of transformer components of the matrix transformer.
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