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    Sodium and buffer source cartridges for use in a modular controlled compliant flow path
    142.
    发明授权
    Sodium and buffer source cartridges for use in a modular controlled compliant flow path 有权
    钠和缓冲源筒，用于模块化控制顺应流路

    公开(公告)号：US09526822B2

    公开(公告)日：2016-12-27

    申请号：US13757722

    申请日：2013-02-01

    Applicant: Medtronic, Inc.

    Inventor： Thomas E. Meyer ,  David B. Lura ,  Bryant J. Pudil ,  Martin T. Gerber

    IPC: A61M1/16 ,  A61M1/36

    CPC classification number: A61M1/3621 ,  A61M1/16 ,  A61M1/1605 ,  A61M1/165 ,  A61M1/1658 ,  A61M1/1666 ,  A61M1/3609 ,  A61M1/3627 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/505 ,  A61M2230/65

    Abstract: Systems and methods for using a sodium chloride source and a buffer source such as sodium bicarbonate in a controlled compliant flow path to generate from water a physiologically compatible fluid having a suitable level of a sodium ion and/or a buffer for use in hemodialysis, hemodiafiltration and hemofiltration. The system has a conditioning flow path that has at least a salination valve or salination pump, and at least one container has at least one solute in excess of the solubility of that solute. At least one of the solutes is a buffer source or sodium chloride. The conditioning flow path is in fluid communication with a controlled compliant flow path. The conditioning flow path can selectively meter fluid into and out of the controlled compliant flow path.

    Abstract translation: 在受控的顺应性流动路径中使用氯化钠源和缓冲源（例如碳酸氢钠）的系统和方法，从水中产生具有适合水平的钠离子和/或缓冲液的生理学相容的液体，用于血液透析，血液透析 和血液滤过。 该系统具有至少具有盐化阀或盐化泵的调节流动路径，并且至少一个容器具有超过该溶质的溶解度的至少一个溶质。 至少一种溶质是缓冲源或氯化钠。 调节流动路径与受控制的顺应流动路径流体连通。 调节流动路径可以选择性地将流体进入和流出被控制的顺应流动路径。

    CANNULA CONFIGURED TO DELIVER TEST STIMULATION
    143.
    发明申请
    CANNULA CONFIGURED TO DELIVER TEST STIMULATION 审中-公开
    CANNULA配置提供测试刺激

    公开(公告)号：US20160310751A1

    公开(公告)日：2016-10-27

    申请号：US15200275

    申请日：2016-07-01

    Applicant: Medtronic, Inc.

    Inventor： Eric H. Bonde ,  Martin T. Gerber

    IPC: A61N1/372 ,  A61N1/36 ,  A61N1/05 ,  A61B17/34 ,  A61B90/00

    CPC classification number: A61N1/37241 ,  A61B17/3415 ,  A61B90/39 ,  A61B2017/00039 ,  A61B2090/3937 ,  A61N1/0551 ,  A61N1/0558 ,  A61N1/08 ,  A61N1/36014 ,  A61N1/3605

    Abstract: The disclosure is directed to an implant tool and cannula used to facilitate the implantation of a medical device into a patient. The implant tool includes a housing that is held by a user and a needle attached to the housing. The cannula may be positioned over the needle and delivered to a target tissue within the patient. The cannula includes an electrode at a distal portion to deliver test stimulation to confirm the location of the target site or placement of the implant tool relative to the target site before removing the needle of the implant tool. In this manner, the cannula may be repositioned within the patient until the position of the implant tool and cannula relative to the target site is verified with the test stimulation.

    Abstract translation: 本公开涉及用于促进将医疗装置植入患者体内的植入物工具和套管。 植入物工具包括由使用者保持的壳体和附接到壳体的针。 套管可以定位在针上方并且被递送到患者体内的目标组织。 插管包括在远端部分处的电极，以在移除植入物工具的针之前递送测试刺激以确认目标部位的位置或植入物工具相对于目标部位的放置。 以这种方式，套管可以在患者体内重新定位，直到用测试刺激验证植入物工具和套管相对于目标部位的位置。

    REPLENISHING UREASE IN DIALYSIS SYSTEMS USING UREASE POUCHES
    144.
    发明申请
    REPLENISHING UREASE IN DIALYSIS SYSTEMS USING UREASE POUCHES 审中-公开
    使用UREASE POUCHES在透析系统中进行补救

    公开(公告)号：US20150367060A1

    公开(公告)日：2015-12-24

    申请号：US14644576

    申请日：2015-03-11

    Applicant: Medtronic, Inc.

    Inventor： Martin T. Gerber ,  Christopher M. Hobot

    IPC: A61M1/34 ,  B01D15/20 ,  A61M1/36

    CPC classification number: B01D15/203 ,  A61M1/1696 ,  A61M2202/0057 ,  A61M2205/18 ,  A61M2205/33

    Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis using urease pouches. The sorbent cartridge is configured to allow insertion of a urease pouch or injection of a urease solution into the sorbent cartridge containing a urease pouch. The sorbent module can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.

    Abstract translation: 用于在吸附剂盒中补充尿素酶的装置和方法，用于使用脲酶袋的吸附剂透析。 吸附剂盒构造成允许将脲酶袋插入或将尿素酶溶液注入含有脲酶袋的吸附剂盒中。 吸附剂模块还可以包含用于从废透析液中去除尿素以外的毒素的其它可再充电的吸附剂材料。

    SORBENT POUCH
    145.
    发明申请
    SORBENT POUCH 审中-公开

    公开(公告)号：US20150367052A1

    公开(公告)日：2015-12-24

    申请号：US14637606

    申请日：2015-03-04

    Applicant: Medtronic, Inc.

    Inventor： Martin T. Gerber ,  Christopher M. Hobot

    IPC: A61M1/14

    CPC classification number: B01J20/28052 ,  A61M1/1696

    Abstract: A sorbent pouch for use in sorbent dialysis. The sorbent pouch allows for fluid to freely pass into and through the sorbent materials, while keeping the sorbent materials inside the sorbent pouch.

    Abstract translation: 用于吸附剂透析的吸附剂袋。 吸附剂袋允许流体自由地进入和穿过吸附剂材料，同时将吸附剂材料保持在吸附剂袋内。

    IMPLANTABLE NEUROSTIMULATOR SUPPORTING TRIAL AND CHRONIC MODES
    147.
    发明申请
    IMPLANTABLE NEUROSTIMULATOR SUPPORTING TRIAL AND CHRONIC MODES 审中-公开
    可植入神经细胞支持试验和慢性模式

    公开(公告)号：US20130331909A1

    公开(公告)日：2013-12-12

    申请号：US13968290

    申请日：2013-08-15

    Applicant: Medtronic, Inc.

    Inventor： Martin T. Gerber

    IPC: A61N1/372

    CPC classification number: A61N1/37252 ,  A61N1/08 ,  A61N1/36007 ,  A61N1/36017 ,  A61N1/3605 ,  A61N1/36071 ,  A61N1/36107 ,  A61N1/37211 ,  A61N1/37241

    Abstract: In some examples, a chronic implantable neurostimulator supports trial and chronic modes of operation. In addition, in some examples, the neurostimulator can alternatively include one or more sensors that may or may not function differently in trial and chronic modes. The device may be designed to be used as both a trial neurostimulator and a permanent, or chronic, neurostimulator. A trial neurostimulation period can be used to evaluate the efficacy of the therapy. A percutaneous or implantable trial neurostimulator is used for the trial neurostimulation period. In most cases, the trial period is successful, in which case the trial stimulator is explanted and replaced with a permanent, i.e., “chronic,” implantable stimulator. In accordance with the disclosure, an implantable neurostimulator supports both trial neurostimulation and chronic neurostimulation in the event trial stimulation is successful.

    Abstract translation: 在一些实例中，慢性可植入神经刺激器支持试验和慢性手术方式。 此外，在一些示例中，神经刺激器可以替代地包括一种或多种在试验和慢性模式中可能或可能不起作用的传感器。 该装置可以被设计成既用于试验神经刺激器又可用作永久的或慢性的神经刺激器。 试验神经刺激期可用于评估治疗的疗效。 经皮或植入式试验神经刺激器用于试验神经刺激期。 在大多数情况下，试用期是成功的，在这种情况下，试用刺激器被移植，并被替换为永久的，即“慢性”植入式刺激器。 根据本公开，可植入神经刺激器在试验刺激成功的情况下支持试验神经刺激和慢性神经刺激。

    Peritoneal dialysis intracycle osmotic agent adjustment
    148.
    发明授权
    Peritoneal dialysis intracycle osmotic agent adjustment 有权

    公开(公告)号：US11883576B2

    公开(公告)日：2024-01-30

    申请号：US17024039

    申请日：2020-09-17

    Applicant: Medtronic, Inc.

    Inventor： Martin T. Gerber ,  Christopher M. Hobot

    IPC: A61M1/28 ,  A61K31/7004 ,  A61K31/718 ,  A61M1/16

    CPC classification number: A61M1/282 ,  A61K31/7004 ,  A61K31/718 ,  A61M1/1656 ,  A61M2202/0486 ,  A61M2205/3344 ,  A61M2205/50 ,  A61M2230/30

    Abstract: The invention relates to systems and methods for making intracycle adjustments to an osmotic agent concentration of peritoneal dialysate inside the peritoneal cavity of a patient. The systems and methods include osmotic agent sources, flow paths, and processors to adjust the osmotic agent concentration of dialysate in the peritoneal cavity of the patient. The method can include infusing peritoneal dialysate containing an osmotic agent into the peritoneal cavity of a patient; monitoring one or more patient parameters; and adjusting the osmotic agent concentration of the peritoneal dialysate in the peritoneal cavity of the patient by infusing a concentrated osmotic agent solution or by infusing sterile fluid into the peritoneal cavity of the patient using an on-line peritoneal dialysis machine. The system can include a peritoneal dialysis cycler.

    Determining nerve location relative to electrodes
    149.
    发明授权
    Determining nerve location relative to electrodes 有权

    公开(公告)号：US11589810B2

    公开(公告)日：2023-02-28

    申请号：US16595195

    申请日：2019-10-07

    Applicant: Medtronic, Inc.

    Inventor： Martin T. Gerber ,  Steven M. Goetz ,  Christopher Poletto

    IPC: A61B5/00 ,  A61N1/372 ,  A61N1/36 ,  A61N1/05

    Abstract: An implantable nerve stimulator is implanted in a patient near a nerve target. The implantable nerve stimulator has a plurality of electrodes through which stimulation is provided to the nerve target. The relative location of the nerve target and the electrodes may be determined by applying stimulation to the nerves via each of the electrodes, determining an effect of the stimulation for each of the electrodes, and mapping a location of the nerve relative to the electrodes based on the effect of the stimulation for each of the electrodes.

    Fluid sensor apparatus
    150.
    发明授权
    Fluid sensor apparatus 有权

    公开(公告)号：US11313804B2

    公开(公告)日：2022-04-26

    申请号：US15677261

    申请日：2017-08-15

    Applicant: Medtronic, Inc.

    Inventor： David B. Lura ,  Shawn Kelley ,  Martin T. Gerber

    IPC: G01N21/80 ,  G01N21/78 ,  G01N21/64 ,  G01N21/77

    Abstract: The invention relates to a fluid sensor apparatus and a related sensor card for determining and/or monitoring a pH and/or solute concentration in a fluid. The fluid sensor apparatus can be used in any application requiring the detection of fluid components or concentrations of solutes, and in an exemplary embodiment, is used to detect ammonia concentration and/or pH in dialysis fluid. The fluid sensor apparatus has a camera, a light source positioned opposite to the camera, and a receiving slot for positioning a removable sensor card between the camera and the light source such that both sides of the sensor card are exposed to the sampled fluid.

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