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11.发明授权公开(公告)号：US12019079B2
公开(公告)日：2024-06-25
申请号：US16966197
申请日：2018-09-24
申请人： ECOLE CENTRALE DE LYON , UNIVERSITE PARIS-SACLAY , UNIVERSITE DE PARIS , ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
CPC分类号： G01N33/6893 , G01N21/8851 , G06T7/0012 , G01N2021/887 , G01N2800/10 , G06T2207/30008
摘要： The invention relates to a non-invasive process for evaluating the quality of one or more dense connective tissue(s) in a patient, comprising the following steps: a) Analyzing the profile of the microrelief of a cutaneous replica of a portion of the skin of said patient by at least one of the following step: a1. visually assessing on picture(s) of said cutaneous replica the line shape and the anisotropy of the lines; and/or a2. Determining, on picture(s) of said cutaneous replica, the roughness index of the microrelief with an optical sensor, b) identifying cutaneous replica of “stage 1”, representative of healthy skins, and cutaneous replica of “stage 2” representative of altered skins, a cutaneous replica of stage 2 being indicative of low quality of the one or more dense connective tissue(s) in the patients body.
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12.发明公开公开(公告)号：US20240016445A1
公开(公告)日：2024-01-18
申请号：US18251927
申请日：2021-11-05
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , ECOLE CENTRALE DE LYON , ECOLE NATIONALE DES TRAVAUX PUBLICS DE L'ETAT
IPC分类号： A61B5/00
CPC分类号： A61B5/442 , A61B5/0059 , A61B5/0053 , A61B5/7235
摘要： A non-invasive method for measuring a physical quantity representative of the elasticity of a material, including: determining the phase velocities of the fundamental mode of the various components of a shear wave generated at the surface of the material, along a measurement axis, the set of pairs, each formed by a frequency f, and the phase velocity Vi of the fundamental mode determined for the frequency fi, forming a dispersion curve of the fundamental mode in a measurement direction parallel to the measurement axis, wherein the index i is an order number of the frequency fi and of the phase velocity Vi, and transforming the dispersion curve into a profile of phase velocities as a function of depth, the phase velocity at a given depth being a physical quantity representative of the elasticity of a material at the depth.
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公开(公告)号：US11769894B2
公开(公告)日：2023-09-26
申请号：US16972928
申请日：2019-05-31
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , UNIVERSITÉ GRENOBLE ALPES , ECOLE CENTRALE DE LYON , UNIVERSITÉ CLAUDE BERNARD LYON 1
IPC分类号： H01M8/16 , H01M50/491 , C12N9/04 , C12N9/02 , H01M4/86 , H01M4/96 , H01M8/04186 , H01M8/04082 , H01M8/04858 , B82Y30/00 , B82Y40/00
CPC分类号： H01M8/16 , C12N9/001 , C12N9/0006 , H01M4/8657 , H01M4/96 , H01M8/04186 , H01M8/04216 , H01M8/04902 , H01M50/491 , B82Y30/00 , B82Y40/00 , C12Y101/03004 , C12Y101/05 , C12Y103/03005
摘要： The invention relates to a biocell (1) with a biofuel reservoir intended to be brought into contact with a liquid medium and with a fluid medium comprising an oxidant. Said biocell comprises a first electrochemical cell having: an anode (5) comprising a first enzyme capable of catalyzing the oxidation of the biofuel; —a cathode (7) comprising a second enzyme capable of catalyzing the reduction of the oxidant; and —a separating and porous membrane (3), electrically insulating, and permeable to said liquid medium, placed between the anode (5) and the cathode (7). Said biocell (1) being characterized in that it comprises a means for storing the biofuel (3) and for providing the liquid medium to the anode (5), said means comprising a hydrophilic porous material in contact with said anode (5)) and having a basis weight of 500 to 900 g/m2.
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14.发明申请公开(公告)号：US20220317031A1
公开(公告)日：2022-10-06
申请号：US17616925
申请日：2020-06-04
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , CPE LYON FORMATION CONTINUE ET RECHERCHE , ECOLE CENTRALE DE LYON , INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON , UNIVERSITE CLAUDE BERNARD LYON 1 , COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES
发明人： Mathieu DUPOY , Maryse FOURNIER , Taha BENYATTOU , Cécile JAMOIS , Lotfi BERGUIGA , Nicolas GAIGNEBET , Thomas GEHIN
IPC分类号： G01N21/35
摘要： A method for analysing a sample uses a resonant support. The sample extends on the support having a surface on which a plurality of separated photonic crystals extend. The sample extends between a light source and the crystals, wherein a resonance wavelength is associated with each crystal addressing the analyte and the wavelengths of the crystals define a resonance spectral band extending between 2 μm and 20 μm. The transmission or reflection of light by each crystal addressing the analyte is maximum at the associated resonance wavelength. The method includes illuminating the support by the light source, the light source emitting an illumination lightwave defining an illumination spectral band which at least partially covers the resonance spectral band, such that a plurality of crystals are simultaneously illuminated; acquiring an image of the support, and then determining the presence of the analyte in the sample from the image.
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公开(公告)号：US20220091018A1
公开(公告)日：2022-03-24
申请号：US17448254
申请日：2021-09-21
申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , CPE LYON FORMATION CONTINUE ET RECHERCHE , ECOLE CENTRALE DE LYON , INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON , UNIVERSITE CLAUDE BERNARD LYON 1
IPC分类号： G01N15/14
摘要： An optical particle detector including at least one channel intended to receive a fluid carrying at least one particle, and across which light rays are intended to pass such that the light rays are partially scattered by the at least one particle, a plurality of photodetectors capable of receiving said scattered light rays, wherein the detector includes at least one optical waveguide configured to collect, at least at one entrance of the waveguide, light rays that were not scattered by the at least one particle and having crossed the channel, and to reinject the unscattered light rays into the channel through at least one exit of the waveguide.
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公开(公告)号：US20210364660A1
公开(公告)日：2021-11-25
申请号：US16982429
申请日：2019-03-20
申请人： UNIVERSITE CLAUDE BERNARD LYON 1 , INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , HOSPICES CIVILS DE LYON , CPE LYON FORMATION CONTINUE ET RECHERCHE , ECOLE CENTRALE DE LYON
发明人： Patrick PITTET , Guo-Neng LU , Patrice JALADE , Jean-Marc GALVAN
IPC分类号： G01T1/20
摘要： A multilayer scintillation detector, includes at least three layers superposed on one another, and each extending parallel to a plane, called the detection plane, wherein each layer is formed by a first material, called a scintillation material, capable of interacting with an ionizing radiation and of forming, following the interaction, a scintillation light in a scintillation spectral band; each layer has a plurality of light guides, respectively extending parallel to the detection plane, according to a length, the light guides being disposed, over all or part of their length, parallel to an axis of orientation; the axis of orientation of the light guides of each layer is oriented, in the detection plane, according to an orientation, the orientations of the respective axes of orientation of at least three layers being different from one another, such that each layer has an associated orientation; and the scintillation material has a first refractive index.
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17.发明授权公开(公告)号：US11121549B2
公开(公告)日：2021-09-14
申请号：US16630732
申请日：2018-07-13
发明人： Selle Toure , Florent Morel , Serge Poullain
摘要： A power flow control device intended to be used in a mesh network. The device includes a first voltage source connected between a first terminal (B1) and a third terminal (B3). A second voltage source is connected between a second terminal (B2) and the third terminal (B3). A current source is connected alternately to the first voltage source and the second voltage source and configured to ensure a transfer of energy between the first voltage source and the second voltage source. A switching means is arranged to allow the current source to be connected alternately in parallel with the first voltage source or in parallel with the second current source.
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公开(公告)号：US11045907B2
公开(公告)日：2021-06-29
申请号：US15762482
申请日：2016-09-22
申请人： Manutech-USD , Ecole Nationale d'Ingenieurs de Saint-Etienne , Ecole Centrale de Lyon , Centre National de la Recherche Scientifique (C.N.R.S.)
IPC分类号： B33Y10/00 , B33Y30/00 , B33Y40/00 , B29C64/153 , B23K26/354 , B29C64/30 , B23K26/34 , B28B1/00
摘要： A system of additive-manufacturing by laser melting of a powder bed. The system includes a first laser unit selectively emitting a first laser beam to form at least one layer of material by melting the powder bed; a second laser unit selectively emitting a second laser beam to machine at least a portion of the layer of material; and an optical unit enabling to focus the first laser beam on the powder bed to be melted and the second laser beam on the layer of material to be machined. The system is able to produce a part by successive stacking of melted then machined layers of material. A process of additive-manufacturing by laser melting of a powder bed is also contemplated.
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公开(公告)号：US20200088712A1
公开(公告)日：2020-03-19
申请号：US16466877
申请日：2017-11-22
申请人： ECOLE CENTRALE DE LYON , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) , ECOLE NATIONALE D'INGENIEURS DE SAINT ETIENNE , INSTITUT ENSEIGNEMENT SUPERIEUR ET RECHERCHE EN ALIMENTATION, SANTE ANIMALE, AGRONOMIQUES ET
IPC分类号： G01N33/487 , G01N21/65 , G01N1/28
摘要： The present invention concerns an in vitro process for diagnosing joint disease in a mammal and/or determining the type of joint disease and/or determining the stage of said disease and/or predicting the course of said disease, comprising the following steps: a) depositing a drop of a synovial fluid sample from said mammal onto a flat substrate made of an inorganic material, such as glass; b) drying the drop deposited in step a); c) measuring at least one parameter indicative of the morphological features of the drop dried in step b), whereby a value for said parameter is obtained, and d) comparing each value measured in step c) with a reference value representative of a reference synovial fluid, characterized in that said parameter is selected from (i) the maximum height (H) of the bead formed on the surface of the drop, (ii) the area of the drop and (iii) the surface profile (Z) of the drop.
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公开(公告)号：US10480972B2
公开(公告)日：2019-11-19
申请号：US15949999
申请日：2018-04-10
申请人： EFS SA , ECOLE CENTRALE DE LYON , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , UNIVERSITE CLAUDE BERNARD LYON 1 , INSTITUT NATIONAL des SCIENCES APPLIQUEES DE LYON
摘要： A control method for an apparatus for ultrasonically measuring the flow rate of a fluid in a measuring channel, including a measuring channel whose one end is equipped with a first transducer and the other end is equipped with a second transducer, each transducer emitting ultrasonic waves to the other transducer, and receiving waves generated by the other transducer, where, in a first step, the first transducer emits waves to the second transducer, and in a second step, which can be simultaneous with the first one, the second transducer emits waves prior to the reception of the waves emitted by the first transducer.
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