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11.发明申请PHOSPHOLIPASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 审中-公开磷脂，核酸编码及其制备与使用方法公开(公告)号：US20120100581A1
公开(公告)日：2012-04-26
申请号：US13090682
申请日：2011-04-20
申请人： SVETLANA GRAMATIKOVA , GEOFF HAZLEWOOD , DAVID LAM , NELSON R. BARTON , BLAKE G. STURGIS , DAN E. ROBERTSON , JINCAI LI , JOEL A. KREPS , RODERICK JAMES FIELDING , ROBERT C. BROWN , AMIT VASAVADA , XUQIU TAN , ADRIAN BADILLO , WILHELMUS P. VAN HOEK , GISELLE JANSSEN , CHARLES ISAAC , MARK J. BURK
发明人： SVETLANA GRAMATIKOVA , GEOFF HAZLEWOOD , DAVID LAM , NELSON R. BARTON , BLAKE G. STURGIS , DAN E. ROBERTSON , JINCAI LI , JOEL A. KREPS , RODERICK JAMES FIELDING , ROBERT C. BROWN , AMIT VASAVADA , XUQIU TAN , ADRIAN BADILLO , WILHELMUS P. VAN HOEK , GISELLE JANSSEN , CHARLES ISAAC , MARK J. BURK
IPC分类号： C12P7/64 , C12N9/20 , C12S99/00 , C12S3/00 , C12P41/00 , C12N5/10 , C07C53/00 , C12N15/63 , C12N1/21 , C12N1/15 , C12N1/19 , C07H21/00 , C12S1/00
CPC分类号： C12N9/16 , C07K2319/00 , C12N9/18 , C12N9/20 , C12N15/8242 , C12N15/8247 , C12P7/6418 , C12P7/6445 , C12P7/6481
摘要： The invention provides novel polypeptides having phospholipase activity, including, e.g., phospholipase A, B, C and D activity, patatin activity, phosphatidic acid phosphatases (PAP)) and/or lipid acyl hydrolase (LAH) activity, nucleic acids encoding them and antibodies that bind to them. Industrial methods, e.g., oil degumming, and products comprising use of these phospholipases are also provided.
摘要翻译： 本发明提供具有磷脂酶活性的新型多肽，包括例如磷脂酶A，B，C和D活性，patatin活性，磷脂酸磷酸酶（PAP））和/或脂质酰基水解酶（LAH）活性，编码它们的核酸和抗体 绑定到他们。 还提供了工业方法，例如油脱胶，以及包含使用这些磷脂酶的产品。
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12.发明授权Xylanases, nucleic acids encoding them and methods for making and using them 有权木聚糖酶，编码它们的核酸以及制备和使用它们的方法公开(公告)号：US08043839B2
公开(公告)日：2011-10-25
申请号：US12279326
申请日：2007-02-14
申请人： David Weiner , David Blum , Alexander Varvak , Shaun Healey , Kristine Chang , Geoff Hazlewood , Thomas Todaro , Grace Desantis , Hwai Chang , Connie Jo Hansen , Scott W. Beaver , Thomas Woodward , Charles Hancock
发明人： David Weiner , David Blum , Alexander Varvak , Shaun Healey , Kristine Chang , Geoff Hazlewood , Thomas Todaro , Grace Desantis , Hwai Chang , Connie Jo Hansen , Scott W. Beaver , Thomas Woodward , Charles Hancock
IPC分类号： C12N9/24 , C12N1/20 , C12N1/15 , C12N1/16 , C12N1/19 , C12N15/70 , C12P21/06 , C07H21/04 , A01H5/00
CPC分类号： C12N9/248 , A23K10/12 , A23K20/163 , A23L5/00 , A23L7/00 , A23L29/30 , A23L31/00 , A23L31/10 , A23L33/125 , A23V2002/00 , C12N9/2405 , C12N9/2437 , C12N9/2482 , C12N9/2488 , C12N9/2494 , C12P19/02 , C12P19/14 , C12Y302/01008 , D06L4/40 , D06L4/70 , D21C3/003 , D21C9/10 , D21H17/005 , Y02E50/16
摘要： The invention relates to enzymes having xylanase, mannanase and/or glucanase activity, e.g., catalyzing hydrolysis of internal β-1,4-xylosidic linkages or endo-β-1,4-ghicanase linkages; and/or degrading a linear polysaccharide beta-1,4-xylan into xylose. Thus, the invention provides methods and processes for breaking down hemicellulose, which is a major component of the cell wall of plants, including methods and processes for hydrolyzing hemicelluloses in any plant or wood or wood product, wood waste, paper pulp, paper product or paper waste or byproduct. In addition, methods of designing new xylanases, mannanases and/or glucanases and methods of use thereof are also provided. The xylanases, mannanases and/or glucanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及具有木聚糖酶，甘露聚糖酶和/或葡聚糖酶活性的酶，例如催化内部-1,4-木糖苷键或内切-1,4-羟基化酶键的水解; 和/或将线性多糖β-1,4-木聚糖降解成木糖。 因此，本发明提供了分解作为植物细胞壁的主要成分的半纤维素的方法和方法，包括在任何植物或木材或木制品，木材废料，纸浆，纸制品中水解半纤维素的方法和方法， 废纸或副产品。 此外，还提供了设计新的木聚糖酶，甘露聚糖酶和/或葡聚糖酶的方法及其使用方法。 木聚糖酶，甘露聚糖酶和/或葡聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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13.发明申请XYLANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 有权XYLANASES，核酸编码它们及其制备和使用方法公开(公告)号：US20090221051A1
公开(公告)日：2009-09-03
申请号：US12402421
申请日：2009-05-07
申请人： Brian STEER , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
发明人： Brian STEER , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及木聚糖酶和编码木聚糖酶的多核苷酸。 此外，还提供了设计新的木聚糖酶的方法及其使用方法。 木聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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14.发明申请XYLANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 有权XYLANASES，核酸编码它们及其制备和使用方法公开(公告)号：US20090155238A1
公开(公告)日：2009-06-18
申请号：US12279326
申请日：2007-02-14
申请人： David Weiner , David Blum , Alexander Varvak , Shaun Healey , Kristine Chang , Geoff Hazlewood , Thomas Todaro , Grace Desantis , Hwai Chang , Connie Jo Hansen , Scott W. Beaver , Thomas Woodward , Charles Hancock
发明人： David Weiner , David Blum , Alexander Varvak , Shaun Healey , Kristine Chang , Geoff Hazlewood , Thomas Todaro , Grace Desantis , Hwai Chang , Connie Jo Hansen , Scott W. Beaver , Thomas Woodward , Charles Hancock
IPC分类号： A61K38/47 , C12N15/11 , C07H21/04 , C12N15/00 , C12N5/06 , C12N1/21 , C12N1/19 , C12P7/02 , A23K1/165 , D06L3/11 , C12P7/10 , D21C3/00 , C12N5/04 , A01K67/027 , A01H5/00 , C12N9/24 , C12P21/04
CPC分类号： C12N9/248 , A23K10/12 , A23K20/163 , A23L5/00 , A23L7/00 , A23L29/30 , A23L31/00 , A23L31/10 , A23L33/125 , A23V2002/00 , C12N9/2405 , C12N9/2437 , C12N9/2482 , C12N9/2488 , C12N9/2494 , C12P19/02 , C12P19/14 , C12Y302/01008 , D06L4/40 , D06L4/70 , D21C3/003 , D21C9/10 , D21H17/005 , Y02E50/16
摘要： The invention relates to enzymes having xylanase, mannanase and/or glucanase activity, e.g., catalyzing hydrolysis of internal β-1,4-xylosidic linkages or endo-β-1,4-ghicanase linkages; and/or degrading a linear polysaccharide beta-1,4-xylan into xylose. Thus, the invention provides methods and processes for breaking down hemicellulose, which is a major component of the cell wall of plants, including methods and processes for hydrolyzing hemicelluloses in any plant or wood or wood product, wood waste, paper pulp, paper product or paper waste or byproduct. In addition, methods of designing new xylanases, mannanases and/or glucanases and methods of use thereof are also provided. The xylanases, mannanases and/or glucanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及具有木聚糖酶，甘露聚糖酶和/或葡聚糖酶活性的酶，例如催化内部β-1,4-木糖苷键或内-A-1,4-ghicanase键的水解; 和/或将线性多糖β-1,4-木聚糖降解成木糖。 因此，本发明提供了分解作为植物细胞壁的主要成分的半纤维素的方法和方法，包括在任何植物或木材或木制品，木材废料，纸浆，纸制品中水解半纤维素的方法和方法， 废纸或副产品。 此外，还提供了设计新的木聚糖酶，甘露聚糖酶和/或葡聚糖酶的方法及其使用方法。 木聚糖酶，甘露聚糖酶和/或葡聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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公开(公告)号：US07547534B2
公开(公告)日：2009-06-16
申请号：US10517939
申请日：2003-06-16
申请人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
发明人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及木聚糖酶和编码木聚糖酶的多核苷酸。 此外，还提供了设计新的木聚糖酶的方法及其使用方法。 木聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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16.发明申请公开(公告)号：US20090053191A1
公开(公告)日：2009-02-26
申请号：US11625765
申请日：2007-01-22
申请人： Svetlana GRAMATIKOVA , Geoff Hazlewood , David Lam , Nelson R. Barton , Blake G. Sturgis , Dan E. Robertson , Jincai Li , Joel A. Kreps , Roderick James Fielding , Robert C. Brown , Amit Vasavada , Xuqiu Tan , Adrian Badillo , Wilhelmus P. Van Hoek , Giselle Janssen , Charles Isaac , Mark J. Burk
发明人： Svetlana GRAMATIKOVA , Geoff Hazlewood , David Lam , Nelson R. Barton , Blake G. Sturgis , Dan E. Robertson , Jincai Li , Joel A. Kreps , Roderick James Fielding , Robert C. Brown , Amit Vasavada , Xuqiu Tan , Adrian Badillo , Wilhelmus P. Van Hoek , Giselle Janssen , Charles Isaac , Mark J. Burk
IPC分类号： A61K38/46 , C12N15/11 , C07H21/04 , C12P19/34 , C12P21/04 , C12N15/00 , C12N1/20 , C12N5/06 , C12N1/19 , C12N5/04 , A01K67/027 , A01H5/00 , C07H21/02 , C12N9/20 , C12N11/14 , C40B40/10 , C12N11/08 , C07K16/18 , G06F19/00 , C11D7/42 , C11D3/386 , C12N15/82 , C12P7/64 , C10G32/00 , A61K31/7088 , A61K38/00 , C12Q1/44
CPC分类号： C12N9/16 , C07K2319/00 , C12N9/18 , C12N9/20 , C12N15/8242 , C12N15/8247 , C12P7/6418 , C12P7/6445 , C12P7/6481
摘要： The invention provides novel polypeptides having phospholipase activity, including, e.g., phospholipase A, B, C and D activity, patatin activity, lipid acyl hydrolase (LAH) activity, nucleic acids encoding them and antibodies that bind to them. Industrial methods, e.g., oil degumming, and products comprising use of these phospholipases are also provided.
摘要翻译： 本发明提供具有磷脂酶活性的新型多肽，包括例如磷脂酶A，B，C和D活性，patatin活性，脂质酰基水解酶（LAH）活性，编码它们的核酸和与它们结合的抗体。 还提供了工业方法，例如油脱胶，以及包含使用这些磷脂酶的产品。
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公开(公告)号：US20060003433A1
公开(公告)日：2006-01-05
申请号：US10517939
申请日：2003-06-16
申请人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
发明人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
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18.发明申请Phosholipases, nucleic acids encoding them and methods for making and using them 有权磷脂酶，编码它们的核酸和制备和使用它们的方法公开(公告)号：US20050108789A1
公开(公告)日：2005-05-19
申请号：US10796907
申请日：2004-03-08
CPC分类号： C12N15/8242 , C07K2319/00 , C12N9/16 , C12N9/18 , C12N9/20 , C12N15/8247 , C12P7/6418 , C12P7/6481
摘要： The invention provides novel polypeptides having phospholipase activity, including, e.g., phospholipase A, B, C and D activity, patatin activity, lipid acyl hydrolase (LAH) activity, nucleic acids encoding them and antibodies that bind to them. Industrial methods, e.g., oil degumming, and products comprising use of these phospholipases are also provided.
摘要翻译： 本发明提供具有磷脂酶活性的新型多肽，包括例如磷脂酶A，B，C和D活性，patatin活性，脂质酰基水解酶（LAH）活性，编码它们的核酸和与它们结合的抗体。 还提供了工业方法，例如油脱胶，以及包含使用这些磷脂酶的产品。
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