Apparatus for automatically performing analyses
    11.
    发明授权
    Apparatus for automatically performing analyses 有权
    用于自动执行分析的装置

    公开(公告)号:US09128072B2

    公开(公告)日:2015-09-08

    申请号:US13121581

    申请日:2009-09-24

    IPC分类号: G01N35/02 G01N35/00 G01N35/10

    摘要: The present invention relates to an apparatus and a method for automatically performing chemical, biochemical and biological analyses using the apparatus. The apparatus comprises: a plurality of subsystems for each performing different operations on microtiter plates; a transporting subsystem for automated movement of microtiter plates in three directions X, Y and Z in order to transport plates from one subsystem to another subsystem within the apparatus; a liquid handler comprising at least two liquid handling probes, wherein said liquid handler is integrated in the transporting subsystem; an insertion/removal subsystem for inserting, removing and storing microtiter plates and equipment for sampling and dilution operations, wherein said insertion/removal subsystem is mechanically operated, without the need for electrical components implemented in that subsystem.

    摘要翻译: 本发明涉及使用该装置自动进行化学,生物化学和生物分析的装置和方法。 该装置包括:多个子系统,用于每个在微量滴定板上执行不同的操作; 运输子系统,用于在三个方向X,Y和Z上自动移动微量滴定板,以便将板从一个子系统传送到设备内的另一个子系统; 液体处理器,其包括至少两个液体处理探针,其中所述液体处理器集成在所述输送子系统中; 用于插入,移除和存储用于取样和稀释操作的微量滴定板和设备的插入/移除子系统,其中所述插入/移除子系统是机械操作的,而不需要在该子系统中实现电气部件。

    Assay based on doped nanoparticles
    16.
    发明授权
    Assay based on doped nanoparticles 失效
    基于掺杂纳米粒子的测定

    公开(公告)号:US07410810B2

    公开(公告)日:2008-08-12

    申请号:US10494390

    申请日:2002-11-04

    IPC分类号: G01N33/551

    摘要: The invention relates to an assay based on resonance energy transfer (RET), comprising a first molecule grope A, which is marked with at least one energy donor, and at least one second molecule group B which is marked with at least one energy acceptor, the donor comprising a molecule or particle which can be energetically excited by an external radiation source and which is fluorescence enabled and the acceptor comprising a molecule or particle which can be excited by energy transfer via the donor with partial or complete quenching of the donor fluorescence, and the donor and/or acceptor comprise luminescing inorganic dope nanoparticles having an expansion of ≦50 nanometers, emitting electromagnetic radiation with stokes or anti-stokes scattering after energetic excitation.

    摘要翻译: 本发明涉及基于共振能量转移(RET)的测定法,其包括用至少一个能量给体标记的第一分子曲线A和至少一个第二分子组B,其被至少一个能量受体标记, 所述供体包含能够被外部辐射源能量激发并且是荧光使能的分子或颗粒,并且所述受体包含分子或颗粒,所述分子或颗粒可以通过供体荧光的部分或完全猝灭通过供体通过能量转移而被激发, 供体和/或受体包括具有<= 50纳米的扩张的发射无机掺杂纳米颗粒,在激发激发后发射具有斯托克斯或反斯托克斯散射的电磁辐射。