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11.发明授权Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof 有权含有低亮度明胶的微胶囊和乳液及其制备和使用方法公开(公告)号：US08034450B2
公开(公告)日：2011-10-11
申请号：US11227961
申请日：2005-09-15
Applicant: Jonathan Michael Curtis , Wei Zhang , Yulai Jin , Colin James Barrow
Inventor： Jonathan Michael Curtis , Wei Zhang , Yulai Jin , Colin James Barrow
CPC classification number: B01J13/10 , A23L29/281 , A23P10/30 , A23P10/35 , A23V2002/00 , Y10S514/962 , Y10S514/963 , Y10T428/2984 , Y10T428/2985 , Y10T428/2991 , A23V2200/224 , A23V2250/5432 , A23V2250/1882
Abstract: Described herein are microcapsules and emulsions prepared from low Bloom gelatin and methods of making and using thereof.
Abstract translation: 本文描述的是由低Bloom明胶制备的微胶囊和乳液及其制备和使用方法。
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公开(公告)号：US20090117194A1
公开(公告)日：2009-05-07
申请号：US11916781
申请日：2006-06-07
Applicant: Adam M. Burja , Helia Radianingtyas , Colin James Barrow , Anthony James Windust
Inventor： Adam M. Burja , Helia Radianingtyas , Colin James Barrow , Anthony James Windust
CPC classification number: C12P7/6427 , A21D8/04 , A23K10/18 , A23K20/158 , A23L29/065 , A23L33/115 , A23L33/12 , A23L33/135 , A23P10/30 , A23V2002/00 , A61K9/4875 , A61K31/20 , C12R1/00 , A23V2200/3262 , A23V2200/332 , A23V2200/328 , A23V2200/02
Abstract: Disclosed are compositions and methods related to eukaryotic microorganisms that can produce unsaturated fatty acids which can be purified and use.
Abstract translation: 公开了与真核微生物相关的组合物和方法，其可以产生可纯化和使用的不饱和脂肪酸。
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公开(公告)号：US20080280994A1
公开(公告)日：2008-11-13
申请号：US11660275
申请日：2005-08-15
Applicant: Junzeng Zhang , Harry Stephen Ewart , Jing Kai Shen , Colin James Barrow
Inventor： Junzeng Zhang , Harry Stephen Ewart , Jing Kai Shen , Colin James Barrow
CPC classification number: A61K36/03 , A23L17/60 , A61K31/05 , A61K31/09 , A61K31/737
Abstract: The invention provides extracts of brown seaweed of the genus Ascophyllum that have valuable pharmacological properties. In particular, compositions of the invention are useful for e.g.: inhibiting alpha-glucosidase activity; preventing or treating conditions mediated by alpha-glucosidase activity; reducing blood glucose levels; preventing or treating diabetes; modulating glucose uptake in adipocytes; preventing or treating obesity; scavenging free radicals; stimulating the immune system; activating macrophages; preventing or treating condition mediated by macrophage activation; and modulating nitric oxide production by macrophages. Methods for using the Ascophyllum extracts of the invention are provided, as are kits comprising Ascophyllum extracts of the invention and instructions for using the extracts.
Abstract translation: 本发明提供了具有有价值的药理学性质的褐藻属褐藻的提取物。 特别地，本发明的组合物可用于例如：抑制α-葡糖苷酶活性; 预防或治疗由α-葡萄糖苷酶活性介导的病症; 降低血糖水平; 预防或治疗糖尿病; 调节脂肪细胞中的葡萄糖摄取; 预防或治疗肥胖症; 清除自由基; 刺激免疫系统; 激活巨噬细胞; 预防或治疗由巨噬细胞活化介导的病症; 并调节巨噬细胞产生的一氧化氮。 提供了使用本发明的伞菌素提取物的方法，以及包含本发明的叶黄素提取物和使用提取物的说明书的试剂盒。
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公开(公告)号：US20120202852A1
公开(公告)日：2012-08-09
申请号：US13500097
申请日：2010-10-25
Applicant: James Barrow , Kelly-Ann Schlegel , Yoheng Shu , Zhi-Qiang Yang
Inventor： James Barrow , Kelly-Ann Schlegel , Yoheng Shu , Zhi-Qiang Yang
IPC: A61K31/4439 , C07D249/04 , A61K31/4192 , C07D277/30 , A61K31/426 , C07D263/34 , A61K31/421 , C07D257/04 , A61K31/41 , C07D413/04 , A61P25/08 , A61P25/00 , A61P25/14 , A61P25/16 , A61P25/28 , A61P25/18 , A61P25/22 , A61P25/30 , C07D401/06
CPC classification number: C07D401/06 , C07D233/64 , C07D249/04 , C07D257/04 , C07D263/32 , C07D271/10 , C07D271/113 , C07D277/28 , C07D413/04 , C07D413/06 , C07D417/14
Abstract: The present invention is directed to heterocycle amide compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T-type calcium channels are involved.
Abstract translation: 本发明涉及作为T型钙通道拮抗剂的杂环酰胺化合物，其可用于治疗或预防涉及T型钙通道的疾病和疾病。 本发明还涉及包含这些化合物的药物组合物以及这些化合物和组合物在预防或治疗涉及T型钙通道的疾病中的用途。
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公开(公告)号：US08163515B2
公开(公告)日：2012-04-24
申请号：US11916781
申请日：2006-06-07
Applicant: Adam M. Burja , Helia Radianingtyas , Colin James Barrow , Anthony James Windust
Inventor： Adam M. Burja , Helia Radianingtyas , Colin James Barrow , Anthony James Windust
IPC: C12P1/00
CPC classification number: C12P7/6427 , A21D8/04 , A23K10/18 , A23K20/158 , A23L29/065 , A23L33/115 , A23L33/12 , A23L33/135 , A23P10/30 , A23V2002/00 , A61K9/4875 , A61K31/20 , C12R1/00 , A23V2200/3262 , A23V2200/332 , A23V2200/328 , A23V2200/02
Abstract: Disclosed are compositions and methods related to eukaryotic microorganisms that can produce unsaturated fatty acids which can be purified and use.
Abstract translation: 公开了与真核微生物相关的组合物和方法，其可以产生可纯化和使用的不饱和脂肪酸。
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Patent Agency Ranking
公开(公告)号：US20110045555A1
公开(公告)日：2011-02-24
申请号：US12668533
申请日：2008-07-11
Applicant: Jaroslav A. Kralovec , Weijie Wang , Colin James Barrow
Inventor： Jaroslav A. Kralovec , Weijie Wang , Colin James Barrow
CPC classification number: C12P7/6409 , C11C1/045 , C12P7/6418 , C12P7/6445 , C12P7/6472 , C12P7/649 , Y02E50/13
Abstract: The disclosed subject matter relates generally to a method for modifying oil, and specifically to a process for increasing the concentration of polyunsaturated fatty acid in an oil composition.
Abstract translation: 所公开的主题一般涉及油的改性方法，具体涉及提高油组合物中多不饱和脂肪酸浓度的方法。
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17.发明申请2,3,4,6-Substituted Pyridyl Derivative Compounds Useful As Beta-Secretase Inhibitors For The Treatment Of Alzheimer's Disease 有权用作治疗阿尔茨海默病的β-分泌酶抑制剂的2,3,4,6-取代的吡啶衍生化合物公开(公告)号：US20070293497A1
公开(公告)日：2007-12-20
申请号：US11791204
申请日：2005-11-18
Applicant: Philippe Nantermet , Hemaka Rajapakse , Harold Selnick , James Barrow , Shaun Stauffer , Joseph Vacca , Keith Moore , Shawn Stachel , Mattahew Stanton
Inventor： Philippe Nantermet , Hemaka Rajapakse , Harold Selnick , James Barrow , Shaun Stauffer , Joseph Vacca , Keith Moore , Shawn Stachel , Mattahew Stanton
IPC: A61K31/44 , A61K31/497 , A61K31/5377 , A61P25/28 , C07D413/14
CPC classification number: C07D413/04 , C07D413/14
Abstract: The present invention is directed to 2,3,4,6-substituted pyridyl derivative compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
Abstract translation: 本发明涉及2,3,4,6-取代的吡啶基衍生物化合物，其是β-分泌酶的抑制剂并且可用于治疗涉及β-分泌酶的疾病，例如阿尔茨海默病 。 本发明还涉及包含这些化合物的药物组合物以及这些化合物和组合物在治疗涉及β-分泌酶的疾病中的用途。
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公开(公告)号：US10166196B2
公开(公告)日：2019-01-01
申请号：US12522826
申请日：2008-01-09
Applicant: Cuie Yan , Wei Zhang , Yulai Jin , Lesek Alexa Demont , Colin James Barrow
Inventor： Cuie Yan , Wei Zhang , Yulai Jin , Lesek Alexa Demont , Colin James Barrow
IPC: A61L9/16 , A61K9/50 , A61K8/11 , A61K8/64 , A61K8/65 , A61K8/73 , A61Q19/00 , A23P10/30 , A23L33/115 , A23L33/12
Abstract: Disclosed are microcapsules with shells that are not animal by-products and methods for preparing and using such microcapsules.
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公开(公告)号：US08987310B2
公开(公告)日：2015-03-24
申请号：US13500097
申请日：2010-10-25
Applicant: James Barrow , Kelly-Ann Schlegel , Yoheng Shu , Zhi-Qiang Yang
Inventor： James Barrow , Kelly-Ann Schlegel , Yoheng Shu , Zhi-Qiang Yang
IPC: C07D401/12 , A61K31/4439 , C07D401/06 , C07D233/64 , C07D249/04 , C07D257/04 , C07D271/10 , C07D277/28 , C07D413/04 , C07D413/06 , C07D417/14 , C07D263/32
CPC classification number: C07D401/06 , C07D233/64 , C07D249/04 , C07D257/04 , C07D263/32 , C07D271/10 , C07D271/113 , C07D277/28 , C07D413/04 , C07D413/06 , C07D417/14
Abstract: The present invention is directed to heterocycle amide compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T-type calcium channels are involved.
Abstract translation: 本发明涉及作为T型钙通道拮抗剂的杂环酰胺化合物，其可用于治疗或预防涉及T型钙通道的疾病和疾病。 本发明还涉及包含这些化合物的药物组合物以及这些化合物和组合物在预防或治疗涉及T型钙通道的疾病中的用途。
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公开(公告)号：US20100173002A1
公开(公告)日：2010-07-08
申请号：US12308045
申请日：2007-06-04
Applicant: Jin Yulai , Colin James Barrow , Wei Zhang , Cuie Yan , Jonathan Michael Curtis , Shawn Moulton , Nancy Beatrice Diogbenou , Lesek Alexa Webber
Inventor： Jin Yulai , Colin James Barrow , Wei Zhang , Cuie Yan , Jonathan Michael Curtis , Shawn Moulton , Nancy Beatrice Diogbenou , Lesek Alexa Webber
IPC: A61K9/16 , A61K31/202 , A61K31/232 , A61K31/575 , A61P35/00 , A61P37/08 , A61P19/02 , A61P9/00 , A61P9/10
CPC classification number: A61K9/5057 , A23L33/10 , A23L33/105 , A23L33/115 , A23L33/16 , A23L33/19 , A23P10/30 , A23V2002/00 , A61K9/1658 , A23V2250/54252 , A23V2250/1868 , A23V2200/224 , A23V2250/187 , A23V2250/1642
Abstract: Disclosed are microcapsules and methods for preparing and using them, as well as methods for improving various properties of microcapsules like impermeability.
Abstract translation: 公开了用于制备和使用它们的微胶囊和方法，以及用于改善微胶囊如不渗透性的各种性质的方法。
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