公开(公告)号：US20230236181A1

公开(公告)日：2023-07-27

申请号：US17702898

申请日：2022-03-24

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: G01N33/543 ,  B01L3/00 ,  G01N21/65 ,  B01D21/26 ,  B01D21/28 ,  B01D21/00

CPC classification number: G01N33/54373 ,  B01D21/0018 ,  B01D21/265 ,  B01D21/283 ,  B01L3/502753 ,  G01N21/658 ,  B01L2200/0647 ,  B01L2300/087 ,  B01L2300/0654 ,  B01L2300/0681 ,  B01L2300/0883 ,  G01N2201/06113

Abstract: A liquid refining apparatus is disclosed. The liquid refining apparatus includes a substrate, a loader which is formed on the substrate and configured to receive a first liquid, a filter which is configured to reduce a concentration of at least one substance contained in the first liquid to obtain a second liquid with a reduced concentration of the at least one substance, a reactor which is configured to mix the second liquid with a reactant for target substance detection to obtain a third liquid containing, among a plurality of substances contained in the second liquid, a first substance which undergoes a predetermined reaction with the reactant and a second substance which does not undergo the predetermined reaction with the reactant, and a separator which is configured to separate the first substance and the second substance.

公开(公告)号：US10857377B2

公开(公告)日：2020-12-08

申请号：US15948545

申请日：2018-04-09

Applicant: Speclipse, Inc.

Inventor： Sung Hyun Pyun ,  Wanki Min ,  Hyoung Soo Shin

IPC: A61N5/06 ,  A61B18/20 ,  A61N5/067 ,  A61B18/00 ,  A61B17/00

Abstract: The present disclosure relates to a method and a device for controlling a laser output. According to an embodiment, there are provided a method for controlling a laser output of a laser device, provided with a laser generator and a handpiece for radiating a laser generated at the laser generator onto a target, and a device performing the method. The method includes the steps of: measuring, by a plurality of distance sensors arranged along a circumference of one end of the handpiece from which the laser is outputted, distances between the plurality of distance sensors and the target; based on the distances between the distance sensors and the target, calculating an effective area which is a region of the target onto which the laser is really radiated; and increasing or reducing the laser output to radiate the laser onto the effective area with a predetermined energy density.

公开(公告)号：USD861164S1

公开(公告)日：2019-09-24

申请号：US29611429

申请日：2017-07-21

Applicant: Speclipse, Inc.

Designer： Sung Hyun Pyun ,  Wanki Min ,  Jin Woo Lee

公开(公告)号：US11892353B2

公开(公告)日：2024-02-06

申请号：US17883724

申请日：2022-08-09

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun Pyun ,  Wan Ki Min

IPC: G01J3/30 ,  G01J3/443 ,  B63B25/16 ,  B63J2/14 ,  F02M21/02 ,  F17C6/00 ,  F17C9/02 ,  F17C9/04 ,  G01J3/42 ,  G01N21/71

CPC classification number: G01J3/443 ,  B63B25/16 ,  B63J2/14 ,  F02M21/0215 ,  F17C6/00 ,  F17C9/02 ,  F17C9/04 ,  F17C2221/033 ,  F17C2227/0164 ,  F17C2227/0185 ,  F17C2227/0339 ,  F17C2227/0348 ,  F17C2227/0358 ,  F17C2265/033 ,  F17C2265/034 ,  F17C2265/037 ,  F17C2265/038 ,  F17C2265/066 ,  F17C2270/0105 ,  G01J2003/423 ,  G01N21/718

Abstract: Disclosed herein are a method for diagnosing a disease of a body tissue by using LIBS (Laser-Induced Breakdown Spectroscopy) comprising: preparing a laser device including: a laser projection module, outputting the laser to a suspicious region of the body tissue, a light receiving module, receiving a plurality of light, a spectrum measurement module, and a guide unit; and projecting the laser to generate plasma by inducing tissue ablation in the suspicious region; wherein the laser projected to the suspicious region has a target area, and wherein the target area has smaller size than the suspicious region such that the target area is located inside the suspicious region.

公开(公告)号：US20190246971A1

公开(公告)日：2019-08-15

申请号：US16043689

申请日：2018-07-24

Applicant: Speclipse, Inc.

Inventor： Sung Hyun PYUN ,  Wanki MIN

IPC: A61B5/00

CPC classification number: A61B5/444 ,  A61B5/0075 ,  A61B5/7267

Abstract: According to an embodiment of the present disclosure, a non-transitory computer readable storage medium which stores one or more non-discrete spectrum analysis programs for lesion tissue detection based on laser spectroscopy is provided. The one or more programs cause an electronic device provided with one or more processors to execute a lesion tissue detection method, and the lesion tissue detection method includes a step of determining whether there is lesion tissue by applying a lesion tissue detection learning model to a result of non-discrete spectrum measurement. The result of the non-discrete spectrum measurement is a result of measuring spectra of all generated light that is generated from a time when a laser is projected onto a sample until the generated light is no longer generated.

公开(公告)号：US20190015681A1

公开(公告)日：2019-01-17

申请号：US15948545

申请日：2018-04-09

Applicant: Speclipse, Inc.

Inventor： Sung Hyun PYUN ,  Wanki MIN ,  Hyoung Soo SHIN

IPC: A61N5/06

Abstract: The present disclosure relates to a method and a device for controlling a laser output. According to an embodiment, there are provided a method for controlling a laser output of a laser device, provided with a laser generator and a handpiece for radiating a laser generated at the laser generator onto a target, and a device performing the method. The method includes the steps of: measuring, by a plurality of distance sensors arranged along a circumference of one end of the handpiece from which the laser is outputted, distances between the plurality of distance sensors and the target; based on the distances between the distance sensors and the target, calculating an effective area which is a region of the target onto which the laser is really radiated; and increasing or reducing the laser output to radiate the laser onto the effective area with a predetermined energy density.

公开(公告)号：US20180098726A1

公开(公告)日：2018-04-12

申请号：US15540364

申请日：2017-04-04

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: A61B5/00 ,  A61N5/06 ,  A61B18/20

CPC classification number: A61B5/441 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0082 ,  A61B5/4836 ,  A61B18/203 ,  A61B2017/00061 ,  A61B2018/00452 ,  A61B2018/00785 ,  A61N5/0616 ,  A61N2005/0626 ,  A61N2005/067

Abstract: An aesthetic or medical laser system is disclosed. The laser system includes: a spectrometer configured to measure a spectrum of light which is generated when body tissue is irradiated with a laser for beauty or medical care; a spectrum data comparison unit configured to compare the spectrum of the generated light measured by the spectrometer and a disease diagnosis reference spectrum data DB; and a disease diagnosis unit configured to determine whether there exists a disease in the body tissue based on a result of comparing by the spectrum data comparison unit.

公开(公告)号：US20180085004A1

公开(公告)日：2018-03-29

申请号：US15540366

申请日：2017-04-04

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: A61B5/00 ,  A61B5/103

CPC classification number: A61B5/0095 ,  A61B5/1032 ,  A61B5/1075 ,  A61B5/444 ,  A61B5/4887 ,  A61B5/7278

Abstract: According to one embodiment, a system for diagnosing a pigmented lesion is provided. The system includes: a sound detector configured to detect a photoacoustic wave which is generated when a first laser is irradiated onto a target having a pigmented lesion; a disease diagnosis unit configured to determine a type of the pigmented lesion based on generated light which is generated when a second laser is irradiated onto the target; and a pigmented lesion diagnosis unit configured to calculate at least one of a depth and a thickness of the pigmented lesion based on a time at which the photoacoustic wave is detected and laser irradiation time information on the first laser irradiated onto the target.

公开(公告)号：US20170281077A1

公开(公告)日：2017-10-05

申请号：US15477995

申请日：2017-04-03

Applicant: Speclipse, Inc.

Inventor： Sung Hyun PYUN ,  Wanki MIN

IPC: A61B5/00 ,  A61N5/06 ,  A61B18/20

CPC classification number: A61B5/4836 ,  A61B5/0013 ,  A61B5/0075 ,  A61B5/0082 ,  A61B5/441 ,  A61B18/203 ,  A61B2017/00061 ,  A61B2018/0047 ,  A61B2018/00785 ,  A61B2018/0091 ,  A61N5/0616 ,  A61N2005/0626 ,  A61N2005/0644 ,  A61N2005/067

Abstract: An aesthetic or medical system is provided. The aesthetic or medical system includes: a laser irradiation device configured to generate a laser and project the laser onto body tissue; a probe configured to collect light which is generated when the laser is projected onto the body tissue; and an analysis unit configured to diagnose a disease by analyzing a spectrum of the light collected by the probe, and the probe is detachably connected to the laser irradiation device.

公开(公告)号：US20240219383A1

公开(公告)日：2024-07-04

申请号：US18113108

申请日：2023-02-23

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN ,  Chang Su JEON ,  In Su KIM ,  Eun Yeong SONG

IPC: G01N33/543 ,  G01N33/58

CPC classification number: G01N33/54373 ,  G01N33/588 ,  G01N2470/06

Abstract: A method of measuring a concentration of an analyte in a bodily fluid sample is provided. The method includes introducing the bodily fluid sample containing the analyte into a test strip for a lateral flow assay (LFA) by a first volume to react the analyte with a metal nano probe for surface-enhanced Raman scattering (SERS), introducing a washing liquid into the test strip by a second volume after a first predetermined time interval has elapsed from the introduction of the bodily fluid sample, and performing a surface-enhanced Raman scattering (SERS)-based spectroscopic analysis on at least one of a test area and a control area of the test strip using a spectroscopic device.