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公开(公告)号:US08883185B2
公开(公告)日:2014-11-11
申请号:US13115049
申请日:2011-05-24
申请人: Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Saumya Banerjee , Timothy Sargeant , Joshua Stopek
发明人: Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Saumya Banerjee , Timothy Sargeant , Joshua Stopek
CPC分类号: A61L27/16 , A61K9/06 , A61K31/00 , A61K47/08 , A61K47/18 , A61K47/32 , A61K47/34 , A61L27/18 , A61L27/52 , A61L27/54 , A61L31/145 , A61L2430/38
摘要: The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
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公开(公告)号:US08591929B2
公开(公告)日:2013-11-26
申请号:US13115066
申请日:2011-05-24
申请人: Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla
发明人: Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla
CPC分类号: A61K31/00 , A61L31/145 , A61L31/16 , A61L2300/00
摘要: The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
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公开(公告)号:US20110293699A1
公开(公告)日:2011-12-01
申请号:US13115079
申请日:2011-05-24
申请人: Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Timothy Sargeant , Joshua Stopek
发明人: Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Timothy Sargeant , Joshua Stopek
IPC分类号: A61K47/30 , A61K9/00 , A61K9/127 , A61P31/00 , A61P29/00 , A61P1/00 , A61P25/08 , A61P9/00 , A61P21/02 , A61P35/00 , A61P37/06 , A61K47/32 , A61P23/00
CPC分类号: A61K31/00 , A61K9/0024 , A61K9/06 , A61K47/34 , C08J3/075 , C08J3/246 , C08J2371/02 , A61K2300/00
摘要: The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
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公开(公告)号:US20100298870A1
公开(公告)日:2010-11-25
申请号:US12848691
申请日:2010-08-02
申请人: Ahmad R. Hadba , Walter Skalla
发明人: Ahmad R. Hadba , Walter Skalla
IPC分类号: A61B17/064
CPC分类号: A61B17/064 , A61B2017/00004 , A61B2017/00831 , A61B2017/00893 , A61L31/022 , A61L31/148
摘要: The present disclosure provides absorbable surgical fasteners.
摘要翻译: 本公开提供了可吸收外科紧固件。
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公开(公告)号:US20100048946A1
公开(公告)日:2010-02-25
申请号:US12544457
申请日:2009-08-20
申请人: Ahmad R. Hadba , Walter Skalla , Nadya Belcheva
发明人: Ahmad R. Hadba , Walter Skalla , Nadya Belcheva
IPC分类号: C07C53/50
CPC分类号: C08G18/4252 , A61L24/0042 , A61L24/046 , C08G18/12 , C08G63/672 , C08G63/6856 , C08G63/916 , C08G2190/00 , C08G2230/00 , C09J175/06 , C08L71/02 , C08G18/42
摘要: Compounds are provided which can form bioabsorbable compositions useful as adhesives or sealants for medical/surgical applications.
摘要翻译: 可以提供可形成用作医疗/外科应用的粘合剂或密封剂的生物可吸收组合物的化合物。
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公开(公告)号:US08968783B2
公开(公告)日:2015-03-03
申请号:US13115017
申请日:2011-05-24
申请人: Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla
发明人: Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla
IPC分类号: A61K47/34 , A61K9/00 , A61L27/52 , A61P7/04 , A61P9/00 , A61K47/32 , A61K9/06 , A61K31/00 , A61L24/00 , A61L24/04 , A61L27/18 , A61L31/06 , A61L31/14
CPC分类号: A61K47/10 , A61K9/06 , A61K31/00 , A61K47/32 , A61K47/34 , A61L24/0031 , A61L24/046 , A61L27/18 , A61L27/52 , A61L31/06 , A61L31/145
摘要: The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
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公开(公告)号:US08591950B2
公开(公告)日:2013-11-26
申请号:US13115079
申请日:2011-05-24
申请人: Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Timothy Sargeant , Joshua Stopek
发明人: Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Timothy Sargeant , Joshua Stopek
IPC分类号: A61K47/30 , A61K9/00 , A61K9/127 , A61P31/00 , A61P29/00 , A61P1/00 , A61P25/08 , A61P9/00 , A61P21/02 , A61P35/00 , A61P37/06 , A61K47/32 , A61P23/00
CPC分类号: A61K31/00 , A61K9/0024 , A61K9/06 , A61K47/34 , C08J3/075 , C08J3/246 , C08J2371/02 , A61K2300/00
摘要: The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
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公开(公告)号:US20120064299A1
公开(公告)日:2012-03-15
申请号:US13222801
申请日:2011-08-31
申请人: Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Timothy Sargeant , Joshua Stopek
发明人: Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Timothy Sargeant , Joshua Stopek
摘要: The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
摘要翻译: 本公开涉及水凝胶组合物及其使用方法。 水凝胶组合物可包括在接触时彼此反应的前体以及与引发剂接触时反应的前体。 在实施方案中,所得到的水凝胶可具有不同密度和较不致密区域的交联水平。
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公开(公告)号:US20110293687A1
公开(公告)日:2011-12-01
申请号:US13115049
申请日:2011-05-24
申请人: Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Saumya Banerjee , Timothy Sargeant , Joshua Stopek
发明人: Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Saumya Banerjee , Timothy Sargeant , Joshua Stopek
CPC分类号: A61L27/16 , A61K9/06 , A61K31/00 , A61K47/08 , A61K47/18 , A61K47/32 , A61K47/34 , A61L27/18 , A61L27/52 , A61L27/54 , A61L31/145 , A61L2430/38
摘要: The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
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公开(公告)号:US20110081397A1
公开(公告)日:2011-04-07
申请号:US12888084
申请日:2010-09-22
申请人: Walter Skalla , Nathaniel Mast
发明人: Walter Skalla , Nathaniel Mast
CPC分类号: A61F2/0063 , A61L31/145 , A61L31/146 , A61L31/148
摘要: The present disclosure relates to implants including a porous substrate, a first hydrogel precursor, a second hydrogel precursor and a mesh. The first and second hydrogel precursors are applied to the porous substrate. The mesh has a first portion in contact with the porous substrate and a second portion exposed for tissue contact.
摘要翻译: 本公开涉及包括多孔底物,第一水凝胶前体,第二水凝胶前体和网的植入物。 将第一和第二水凝胶前体施加到多孔基材上。 网状物具有与多孔基底接触的第一部分和暴露于组织接触的第二部分。
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