公开(公告)号：US06645746B1

公开(公告)日：2003-11-11

申请号：US09890821

申请日：2001-11-19

申请人： Noriyuki Kizaki ,  Yukio Yamada ,  Yoshihiko Yasohara ,  Junzo Hasegawa

发明人： Noriyuki Kizaki ,  Yukio Yamada ,  Yoshihiko Yasohara ,  Junzo Hasegawa

IPC分类号： C12N902

CPC分类号： C12N9/0006 ,  C12P7/62 ,  C12P41/00 ,  C12P41/002

摘要： A novel polypeptide for producing tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate, a gene encoding the polypeptide, and a method of using the polypeptide, are provided. The polypeptide has an enzyme activity to asymmetrically reduce tert-butyl (S)-6-chloro-5-hydroxy-3-oxohexanoate to tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate. The polypeptide comprises the amino acid sequence represented by SEQ ID NO. 1 in the Sequence Listing, or the amino acid sequence having at least one amino acid substitution, insertion, deletion, or addition thereof.

摘要翻译： 提供了一种用于生产（3R，5S）-6-氯-3,5-二羟基己酸叔丁酯，编码该多肽的基因以及使用该多肽的方法的新型多肽。 该多肽具有不对称地将（S）-6-氯-5-羟基-3-氧代己酸叔丁酯转化为（3R，5S）-6-氯-3,5-二羟基己酸叔丁酯的酶活性。 多肽包含SEQ ID NO：1所示的氨基酸序列。 或序列表中具有至少一个氨基酸取代，插入，缺失或添加的氨基酸序列。

公开(公告)号：US06221638B1

公开(公告)日：2001-04-24

申请号：US09064750

申请日：1998-04-23

申请人： Yukio Yamada ,  Akira Iwasaki ,  Noriyuki Kizaki ,  Yasuhiro Ikenaka ,  Masahiro Ogura ,  Junzo Hasegawa

发明人： Yukio Yamada ,  Akira Iwasaki ,  Noriyuki Kizaki ,  Yasuhiro Ikenaka ,  Masahiro Ogura ,  Junzo Hasegawa

IPC分类号： C12P1300

CPC分类号： C12P13/001 ,  C12N9/1096 ,  C12P13/005 ,  C12P13/008 ,  C12P13/04 ,  C12P41/006 ,  Y10S435/83

摘要： The method for preparing an optically active (R)-amino compound characterized by the method comprising stereoselectively carrying out amino group transfer by action of an (R)-form-specific transaminase in the co-presence of a ketone compound (amino acceptor), and an amino compound (amino donor) of a racemic form or an (R)-form, to give an optically active (R)-amino compound. According to the present invention, it is made possible to easily prepare at a high yield the optically active (R)-amino compounds and the like having an aryl group and the like at their 1-position, which have been conventionally difficult to prepare.

摘要翻译： 制备光学活性（R） - 氨基化合物的方法，其特征在于在酮化合物（氨基受体）的共存下通过（R） - 形式 - 特异性转氨酶的作用立体选择性地进行氨基转移的方法， 和外消旋形式的氨基化合物（氨基供体）或（R） - 形式，得到光学活性（R） - 氨基化合物。 根据本发明，可以容易地容易地制备其1-位上具有芳基等的光学活性（R） - 氨基化合物等，其通常难以制备。

公开(公告)号：US6083752A

公开(公告)日：2000-07-04

申请号：US876398

申请日：1997-06-16

申请人： Yasuhiro Ikenaka ,  Hirokazu Nanba ,  Masayuki Takano ,  Kazuyoshi Yajima ,  Yukio Yamada ,  Satomi Takahashi

发明人： Yasuhiro Ikenaka ,  Hirokazu Nanba ,  Masayuki Takano ,  Kazuyoshi Yajima ,  Yukio Yamada ,  Satomi Takahashi

IPC分类号： C12N9/80 ,  C12N15/55 ,  C12N15/72 ,  C12P13/06 ,  C12P13/08 ,  C12P13/22 ,  C12N15/00 ,  C12N5/10 ,  C12N9/14

CPC分类号： C12N15/72 ,  C12N9/80 ,  C12P13/06 ,  C12P13/08 ,  C12P13/22

摘要： A DNA fragment coding for a decarbamylase protein improved in thermostability as the result of replacement of at least one base of a DNA fragment coding for a decarbamylase protein derived from a microorganism with another base and the resultant replacement of at least one of the corresponding amino acids, and its production process; a vector containing the DNA fragment; a transformant obtained by transformation with the vector; as well as a decarbamylase improved in thermostability and its production process. Also disclosed is a process for producing a D-.alpha.-amino acid, which comprises converting an N-carbamoyl-D-.alpha.-amino acid into the corresponding D-.alpha.-amino acid in an aqueous medium by the action of a decarbamylase having a thermostable temperature of 65.degree. C. or higher; and collecting the D-.alpha.-amino acid produced.

摘要翻译： 由于将来自微生物的脱氨基甲酰酶蛋白质的至少一个碱基替换为另一碱基的氨基酸残基的至少一个碱基，所以替代了至少一个相应的氨基酸 ，及其生产工艺; 含有DNA片段的载体; 通过用载体转化获得的转化体; 以及改进了热稳定性的脱氨基甲酰酶及其制备方法。 还公开了一种制备D-α-氨基酸的方法，该方法包括通过脱氨基甲酰酶的作用将N-氨基甲酰基-D-α-氨基酸转化成水性介质中的相应的D- 耐热温度在65℃以上; 并收集产生的D-α-氨基酸。

公开(公告)号：US6020059A

公开(公告)日：2000-02-01

申请号：US121055

申请日：1998-07-23

申请人： Yukio Yamada ,  Masao Saito ,  Junji Shinozaki ,  Motohide Takeichi

发明人： Yukio Yamada ,  Masao Saito ,  Junji Shinozaki ,  Motohide Takeichi

IPC分类号： C09J7/00 ,  C09J9/02 ,  C09J163/00 ,  C09J201/00 ,  H01B1/20 ,  H01L21/60 ,  H05K3/32 ,  B32B7/12

CPC分类号： H05K3/323 ,  C09J7/00 ,  C09J9/02 ,  H01L24/29 ,  C09J2201/134 ,  C09J2201/36 ,  H01L2924/07802 ,  H01L2924/07811 ,  H01L2924/14 ,  H05K2201/10674 ,  H05K2203/1189 ,  Y10S428/901 ,  Y10T428/256 ,  Y10T428/287 ,  Y10T428/2991

摘要： A multilayer anisotropic electroconductive adhesive, comprises an anisotropic electroconductive adhesive layer and laminated to at least one side thereof an insulating adhesive layer. The anisotropic electroconductive adhesive layer comprises a film-forming resin and electroconductive particles and has a melt viscosity at 150.degree. C. of 100 poise or higher, and the insulating adhesive layer comprises a latent curing agent and a resin having a functional group and has a melt viscosity at 150.degree. C. of less than 100 poise.

摘要翻译： 多层各向异性导电粘合剂包括各向异性导电粘合剂层，并且在其至少一个侧面层压有绝缘粘合剂层。 各向异性导电粘合剂层包括成膜树脂和导电颗粒，并且在150℃下的熔体粘度为100泊或更高，并且绝缘粘合剂层包含潜在性固化剂和具有官能团的树脂，并且具有 在150℃下的熔融粘度小于100泊。

公开(公告)号：US5998198A

公开(公告)日：1999-12-07

申请号：US981352

申请日：1997-12-19

申请人： Mika Nakayama ,  Chie Miyazaki ,  Osamu Asami ,  Yukio Yamada ,  Koichi Numata ,  Yasushi Oda

发明人： Mika Nakayama ,  Chie Miyazaki ,  Osamu Asami ,  Yukio Yamada ,  Koichi Numata ,  Yasushi Oda

IPC分类号： A62D3/02 ,  B09C1/10 ,  C02F3/34 ,  C12P1/04 ,  B09B3/00

CPC分类号： C12R1/38 ,  B09C1/10 ,  C02F3/34 ,  C12P1/04 ,  C12R1/01 ,  Y10S435/874

摘要： Microorganisms belonging to the genus Burkholderia and having the ability to decompose halogenated hydrocarbon, which are able to decompose 50% or more of 100 ppm of trichloroethylene in 2 days, or decompose 100% of 30 ppm of trichloroethylene in 18 hours, as well as providing a process for decomposing halogenated hydrocarbons in water or soil using those microorganisms.

摘要翻译： PCT No.PCT / JP97 / 01359 Sec。 371 1997年12月19日第 102（e）1997年12月19日PCT PCT 1997年4月18日PCT公布。 WO97 / 40136 PCT公开号 日期：1997年10月30日属于伯克霍尔德氏菌属的微生物，具有分解卤代烃的能力，其能够在2天内分解50ppm或更多的100ppm三氯乙烯，或在18小时内分解100ppm的三氯乙烯100％ ，以及提供使用这些微生物分解水或土壤中的卤代烃的方法。

公开(公告)号：US5565344A

公开(公告)日：1996-10-15

申请号：US917111

申请日：1992-08-07

申请人： Hirokazu Nanba ,  Yukio Yamada ,  Masayuki Takano ,  Yasuhiro Ikenaka ,  Satomi Takahashi ,  Kazuyoshi Yajima

发明人： Hirokazu Nanba ,  Yukio Yamada ,  Masayuki Takano ,  Yasuhiro Ikenaka ,  Satomi Takahashi ,  Kazuyoshi Yajima

IPC分类号： C12N1/21 ,  C12N9/80 ,  C12N15/55 ,  C12P13/04 ,  C12P41/00 ,  C07H19/00 ,  C12N1/12 ,  C12N9/14

CPC分类号： C12P41/009 ,  C12N9/80 ,  C12P13/04

摘要： The present invention is directed to a gene which is related to a D-N-carbamoyl-.alpha.-amino acid amidohydrolase which is an enzyme capable of converting D-N-carbamoyl-.alpha.-amino acids into D-.alpha.-amino acids; a recombinant plasmid in which a DNA fragment containing the gene is incorporated into a vector; a microorganism belonging to the genus Escherichia, Pseudomonas, Flavobacterium, Bacillus, Serratia, Corynebacterium, or Brevibacterium, which is transformed by incorporating the recombinant plasmid thereinto; a process for the production of D-N-carbamoyl-.alpha.-amino acid amidohydrolases, comprising the steps of cultivating the transformed microorganism and collecting the desired product therefrom; a D-N-carbamoyl-.alpha.-amino acid amidohydrolase obtained by the method; and a process for the production of D-.alpha.-amino acids with the aid of an action of the enzyme.The D-N-carbamoyl-.alpha.-amino acid amidohydrolase can be fixed on a support for immobilization and used as an immobilized enzyme.

摘要翻译： PCT No.PCT / JP91 / 01696 Sec。 371日期：1992年8月7日 102（e）日期1992年8月7日PCT 1991年12月6日PCT PCT。 出版物WO92 / 10579 日期1992年6月25日本发明涉及与能够将D-N-氨基甲酰基-α-氨基酸转化为D-氨基酸的酶的D-N-氨基甲酰基-α-氨基酸酰胺水解酶相关的基因。 将含有该基因的DNA片段并入载体的重组质粒; 通过将重组质粒并入而转化的属于埃希氏杆菌属，假单胞菌属，黄杆菌属，芽孢杆菌属，沙雷氏菌属，棒状杆菌属或短杆菌属的微生物; 制备D-N-氨基甲酰基-α-氨基酸酰胺水解酶的方法，包括培养转化的微生物并从其中收集所需产物的步骤; 通过该方法获得的D-N-氨基甲酰基-α-氨基酸酰胺水解酶; 以及借助于酶的作用生产D-氨基酸的方法。 D-N-氨基甲酰基-α-氨基酸酰胺水解酶可以固定在用于固定的载体上并用作固定化酶。

公开(公告)号：US5150166A

公开(公告)日：1992-09-22

申请号：US423770

申请日：1989-10-18

申请人： Yasuhiro Matsuura ,  Hiroaki Kojima ,  Hirofumi Hasegawa ,  Naoto Ohmori ,  Yukio Yamada

发明人： Yasuhiro Matsuura ,  Hiroaki Kojima ,  Hirofumi Hasegawa ,  Naoto Ohmori ,  Yukio Yamada

IPC分类号： B41J11/58 ,  B65H3/44

CPC分类号： B65H3/44 ,  B41J11/58

摘要： An image forming system for copiers, printers and the like having a main body which forms images on sheets of paper inserted therein and a plurality of sheet feeding units selectively attachable to the main body. The main body has a timing roller set which transports the papers to an image forming position with an appropriate timing, and each of the sheet feeding units has a paper feeding system with a take-up roller for supplying papers from the unit directly to the timing roller set without intermediate rollers in the main body. The system further includes side and bottom sheet feeding units selectively attachable to the main body and the side unit includes a guide for guiding sheets from the bottom unit into the main body. The system further includes a separate sheet guide mountable on the bottom unit for guiding sheets into the main body when the side unit is absent from the system. The invention permits the paper feeding construction of the image forming systems to be easily and freely changed as a whole.

摘要翻译： 一种用于复印机，打印机等的图像形成系统，其具有在插入其中的纸张上形成图像的主体和可选择性地附接到主体的多个供纸单元。 主体具有定时辊组，其将纸张以适当的时间运送到成像位置，并且每个送纸单元具有带有卷取辊的送纸系统，该卷取辊用于将纸从该单元直接提供到定时 滚筒在主体中没有中间辊。 该系统还包括可选择性地附接到主体的侧片和底片进给单元，并且侧单元包括用于将片材从底部单元引导到主体中的引导件。 该系统还包括可安装在底部单元上的单独的片材导板，用于当侧面单元不在系统中时将片材引导到主体中。 本发明允许图像形成系统的供纸结构整体上容易且自由地改变。

公开(公告)号：US5017961A

公开(公告)日：1991-05-21

申请号：US374289

申请日：1989-06-29

申请人： Hirofumi Hasegawa ,  Naoto Ohmori ,  Yukio Yamada ,  Narutaka Yoshida

发明人： Hirofumi Hasegawa ,  Naoto Ohmori ,  Yukio Yamada ,  Narutaka Yoshida

IPC分类号： G03G15/04 ,  G03G15/22 ,  G06K15/12

CPC分类号： G03G15/221 ,  G03G15/04 ,  G06K15/1276 ,  G03G15/0435

摘要： An image forming apparatus includes a laser beam radiating unit utilized as a light source, and an optical system that the surface of an original reflects a laser beam radiated from the radiating unit to project an image reflected from the original onto a photosensitive member. In this apparatus, an image is formed selectively in a print mode that an image results from turning on and off the laser beam, in a copy mode that a copy of an original results from exposure of the photosensitive member to the laser beam reflected from the surface of an original or in a composite mode that a composite image is formed of a copy of an original and an image resulting from turning on and off the laser beam. Also, this apparatus comprises a reflector for directing the laser beam to the photosensitive member, and the reflector is automatically set at the reflecting position when the original cover is open or the print mode is selected. Further, this apparatus comprises a lock system for locking an original cover; the lock system works to lock the original cover when the copy mode or the composite mode is selected and to unlock the cover when the print mode is selected.

摘要翻译： 图像形成装置包括用作光源的激光束照射单元以及原稿的表面反射从辐射单元辐射的激光束以将从原稿反射的图像突出到感光构件上的光学系统。 在该装置中，以复印模式选择性地以打印和关闭激光束的图像形成图像，该复制模式是由感光构件的曝光引起的反射的激光束的原稿复制 原稿的表面或复合模式，合成图像由原稿的副本和从打开和关闭激光束产生的图像形成。 此外，该装置包括用于将激光束引导到感光构件的反射器，并且当原始盖打开或选择打印模式时，反射器被自动设置在反射位置。 此外，该装置包括用于锁定原始盖的锁定系统; 当选择复印模式或复合模式时，锁定系统用于锁定原稿盖，并且在选择打印模式时解锁盖。

公开(公告)号：US4978977A

公开(公告)日：1990-12-18

申请号：US376826

申请日：1989-07-07

申请人： Naoto Ohmori ,  Yasuhiro Matsuura ,  Hirofumi Hasegawa ,  Hiroaki Kojima ,  Yukio Yamada

发明人： Naoto Ohmori ,  Yasuhiro Matsuura ,  Hirofumi Hasegawa ,  Hiroaki Kojima ,  Yukio Yamada

IPC分类号： G02B26/10 ,  G02B26/12 ,  H04N1/113 ,  H04N1/23

CPC分类号： G02B26/127

摘要： A laser scanning optical system including a rotatable polygonal mirror for scanning the photosensitive surface with the laser beam in a scanning direction, a lens unit for converging the laser beam reflected by the polygonal mirror on the photosensitive surface, a first reflection mirror for reflecting the laser beam passed though the lens unit to the photosensitive surface, a second reflection mirror for reflecting the laser beam reflected by a part of the first reflection mirror, a sensor arranged to receive the laser beam which is reflected by the second reflection mirror and has passed through a specific position equivalent to the photosensitive surface for generating a synchronizing signal for commanding start of modulation of the laser beam, and first and second lens elements both interposed between the specific position and the sensor so as to keep a conjugate condition therebetween. The first lens element has a positive power only in the direction perpendicular to the scanning direction and provides a magnification smaller than 1 in the direction perpendicular to the scanning direction, while the second lens element has a positive power only in the scanning direction and provides a magnification greater than 1 in the scanning direction.

摘要翻译： 一种激光扫描光学系统，包括用于在扫描方向上用激光束扫描感光表面的可旋转多面镜，用于将由多面镜反射的激光束会聚在感光表面上的透镜单元，用于反射激光的第一反射镜 光束通过透镜单元通过感光表面，用于反射由第一反射镜的一部分反射的激光束的第二反射镜，布置成接收由第二反射镜反射并已经通过的激光束的传感器 相当于用于产生用于指示激光束的调制开始的同步信号的光敏表面的特定位置，以及插入在特定位置和传感器之间以便保持其之间的共轭条件的第一和第二透镜元件。 第一透镜元件仅在垂直于扫描方向的方向上具有正功率，并且在垂直于扫描方向的方向上提供小于1的倍率，而第二透镜元件仅在扫描方向上具有正功率，并且提供 扫描方向的倍数大于1。

公开(公告)号：US4974921A

公开(公告)日：1990-12-04

申请号：US268730

申请日：1988-11-08

申请人： Shin Miyata ,  Hiroaki Kojima ,  Yasuhiro Matsuura ,  Hirofumi Hasegawa ,  Yukio Yamada ,  Naoto Ohmori

发明人： Shin Miyata ,  Hiroaki Kojima ,  Yasuhiro Matsuura ,  Hirofumi Hasegawa ,  Yukio Yamada ,  Naoto Ohmori

IPC分类号： G02B26/12

CPC分类号： G02B26/126

摘要： An apparatus provided with a first reflector for reflecting a light beam deflected by a deflector in a light beam scanning apparatus and a second reflector for directing the light beam from the first reflector toward an image forming point after contacting again the first reflector. The light beam is reciprocated between the first and second reflectors thereby forming a light path of two times the space that they are disposed. A deflector is disposed on a side of the light path extending from the first reflector to the light beam image forming point together with a light beam emitting source which irradiate the light beam on the same level of the light path and make the light path length at both ends of the light beam scanning range equal to each other by arranging an angle between the first and second reflectors.

摘要翻译： 一种设备具有第一反射器，用于将由偏转器偏转的光束反射在光束扫描装置中，以及第二反射器，用于在再次接触第一反射器之后将来自第一反射器的光束引向图像形成点。 光束在第一和第二反射器之间往复运动，从而形成它们所设置的空间的两倍的光路。 偏转器设置在从第一反射器延伸到光束图像形成点的光路的一侧以及将光束照射在光路的同一水平上并使光路长度为 通过在第一和第二反射器之间布置角度，光束扫描范围的两端彼此相等。