Abstract:
A micro structure includes a silicon substrate, an adhesion layer on the silicon substrate, a bias layer on the adhesion layer, and structure layers on the adhesion layer. The two or more structure layers comprise different material compositions and a plurality of holes through at least two of the structure layers. Widths of the plurality of holes are in the range of 0.5-500 nm.
Abstract:
A four-port loop optical circulator includes a first, a second, a third and a fourth optical ports for receiving optical beam therein. The circulator further includes a plurality of optical components. The optical components include a walk-off crystal for generating a vertical optical path displacement for a vertical polarized optical beam and for passing a horizontally polarized optical beam therethrough maintaining a same optical path. The optical components also include a vertical displacement device for shifting an optical path along a vertical direction with a predefined vertical displacement for an optical beam transmitted with a particular polarization. The vertical displacement device is coupled to the walk-off crystal for guiding a beam received from the fourth port to project from the first port.
Abstract:
This invention discloses an optical collimator that includes a built-in tap-out projection optical arrangement for projecting a portion of an incoming beam to a tap-out beam-transmission fiber. In one of the preferred embodiments, the built-in tap-out projection optical arrangement further includes a front surface having an incline angle for projecting a portion of an incoming beam to a tap-out beam transmission fiber. In another preferred embodiment, the built-in tap-out projection optical arrangement further includes a prism having a pair of inclined front surfaces for projecting the incoming beam into an output beam and a tap out beam. In yet another preferred embodiment, the built-in tap-out projection optical arrangement further includes a partially reflective front surface and a reflective mirror projecting the incoming beam into an output beam and a tap out beam. This invention disclosure a dual beam collimator that provides two parallel each other beam with adjustable distance between them in the same diameter as single beam collimator. The dual beam collimator can be expanded into multiple beam collimator also.
Abstract:
A method for establishing an animal model of hepatocellular carcinoma (HCC) bone metastasis, the method including: 1) establishing 97H and LM3 cell clones with stable expression of firefly luciferase (LUC); 2) allowing HCC cells to form bone metastasis in nude mice via intratibial injection; 3) reproducing HCC bone metastasis in nude mice via intracardiac injection of tumor cells; and 4) isolating a sub-population of tumor cells that targets metastasis to bone. The 97H and the LM3 are highly metastatic HCC cell lines transfected with luciferase gene. BALB/cA-nu mice are 4-5 weeks old and maintained in laminar flow cabinets under SPF conditions and received human care throughout an entire study. A cell number for intratibial injection is 0.5×106, and a cell number for intracardiac injection is 1×106.
Abstract:
A micro structure for sensing a substance using light scattering includes a substrate, a first layer on the substrate, wherein the first layer comprises a metallic material, a second layer over the first layer, and a mask layer over the second layer. A plurality of nano holes are formed through the mask layer and the second layer, wherein the plurality of holes are defined in part by internal surfaces on the second layer and the mask layer. Two or more structure layers are formed on the mask layer and the internal surfaces in the plurality of holes. The two or more structure layers comprise different material compositions.
Abstract:
New and improved applications of Raman Scattering are disclosed. These applications may be implemented with or without using an enhanced nano-structured surface that is trademarked as the RamanNanoChip™ disclosed in a pending patent. As a RamanNanoChip™ provides much higher sensitivity in SERS compared with conventional enhance surface, broader scopes of applications are now enabled and can be practically implemented as now disclosed in this application. Furthermore, a wide range of applications is achievable as new and improved Raman sensing applications. By applying the analysis of Raman scattering spectrum, applications can be carried out to identify unknown chemical compositions to perform the tasks of homeland security; food, drug and drinking materials safety; early disease diagnosis environmental monitoring; industrial process monitoring, precious metal and gem authentications, etc.
Abstract:
An optical circulator has a first collimator; a first block of birefringent material; a first compound polarization rotator; a light angle deflector (e.g., Wollaston prism); a second compound polarization rotator; a second block of birefringent material; and a second collimator. Light from the first fiber exits the first collimator along a first path into a first collimated beam that first hits the central plane on a crossing line between the interface and the central plane such that the first collimated beam exits the light angle deflector along a second path substantially parallel to the longitudinal direction and is received by the second fiber. Light from the second fiber exits the second collimator along the second path into a second collimated beam that exits the light angle deflector along a third path and is received by the third fiber.
Abstract:
This invention discloses an optical interleaver that includes a first collimating lens for collimating an input optical signal into collimated beams and a second collimating lens for focusing the collimated parallel beams into an output optical fiber. The interleaver further includes a phase delay difference generating means for generating a phase-delay difference between portions of the collimated parallel beams for generating an interference in the second collimating lens for selectively enhance signal transmission of certain wavelengths. In a preferred embodiment, the phase delay difference generating means comprising a glass plate blocking a portion of the collimated parallel beams for generating a phase delay for a portion of the collimated parallel beams passing therethrough. In another preferred embodiment, the phase delay difference generating means comprising a glass plate having an upper portion covering an upper portion of the collimated parallel beams. The glass plate having a lower portion covering a lower portion of the collimated parallel beams for generating a phase delay difference between the upper portion and lower portion of the collimated parallel beams. In another preferred embodiment, the interleaver further includes a control means for controlling the phase delay difference generating means for selectively generating signal transmission at different wavelengths according to the interference generated in the second collimating lens.
Abstract:
This invention discloses a dual fiber optical component that includes a first holding tube for containing and holding a dual fiber capillary and a collimator lens. The dual fiber capillary has first optical fiber and a second optical fiber with the first optical fiber transmits an input light beam for projecting through the collimator lens as a collimated beam. The dual fiber component further includes a second holding tube containing and holding an optical filter for receiving the collimated beam from the collimator lens. The filter further projecting a portion of the collimated beam back through the collimator lens for transmitting to the second optical fiber of the dual fiber capillary. The first holding tube has a first interface tube end forming with a convex spherical profile and the second holding tube has a second interface tube end forming with a concave spherical profile corresponding to the convex spherical profile of the first interface tube end.
Abstract:
A method for establishing an animal model of hepatocellular carcinoma (HCC) bone metastasis, the method including: 1) establishing 97H and LM3 cell clones with stable expression of firefly luciferase (LUC); 2) allowing HCC cells to form bone metastasis in nude mice via intratibial injection; 3) reproducing HCC bone metastasis in nude mice via intracardiac injection of tumor cells; and 4) isolating a sub-population of tumor cells that targets metastasis to bone. The 97H and the LM3 are highly metastatic HCC cell lines transfected with luciferase gene. BALB/cA-nu mice are 4-5 weeks old and maintained in laminar flow cabinets under SPF conditions and received human care throughout an entire study. A cell number for intratibial injection is 0.5×106, and a cell number for intracardiac injection is 1×106.