PERCUTANEOUS REPAIR OF MITRAL PROLAPSE
    11.
    发明申请

    公开(公告)号:US20190083264A1

    公开(公告)日:2019-03-21

    申请号:US16135560

    申请日:2018-09-19

    Abstract: A mitral valve leaflet repair system may include a delivery catheter having at least one lumen extending proximally from a distal end of the delivery catheter, a plurality of anchor elements disposed within the at least one lumen, each of the plurality of anchor elements being configured to extend through one layer of mitral valve leaflet tissue, and a securing element configured to secure at least two of the plurality of anchor elements together on one side of the mitral valve leaflet tissue. The at least one lumen may include a suction lumen configured to grasp a mitral valve leaflet prior to extending the plurality of anchor elements through one layer of mitral valve leaflet tissue.

    Decalcifying heart valve
    12.
    发明授权

    公开(公告)号:US09987130B2

    公开(公告)日:2018-06-05

    申请号:US13708292

    申请日:2012-12-07

    Inventor: Jan Weber

    Abstract: Vascular valve systems for treating calcified vascular vessel valves by delivery of one or more calcium chelating agents are described. The vascular valve system includes an expandable stent; a valve with a plurality of leaflets, and a hydrogel layer disposed on an outer surface of the stent. The hydrogel layer includes a hydrogel, and a calcium-chelating agent and an acidifying agent disposed within the hydrogel. The calcium-chelating agent and the acidifying agent are covalently bonded to the hydrogel. The hydrogel layer is configured to capture loosened calcium deposits to form a calcium-chelating agent complex covalently bonded to the hydrogel layer. Methods of making the vascular valve systems are also described.

    APPARATUS AND METHOD FOR SEALING A VESSEL PUNCTURE OPENING
    14.
    发明申请
    APPARATUS AND METHOD FOR SEALING A VESSEL PUNCTURE OPENING 审中-公开
    用于密封容器开口的装置和方法

    公开(公告)号:US20160296217A1

    公开(公告)日:2016-10-13

    申请号:US15155589

    申请日:2016-05-16

    Abstract: A device for sealing a puncture opening may include a base frame having a delivery configuration wherein the base frame is retracted to have a relatively smaller overall profile, and a deployed configuration wherein the base frame is extended to have a relatively larger overall profile. The base frame is sized to engage an interior surface of the blood vessel wall in the deployed configuration. A sealing section is coupled to the base frame, the sealing section having an initial configuration wherein the sealing section permits fluid flow, and a barrier configuration wherein the sealing section prevents fluid flow. The sealing section in the barrier configuration is sized to block fluid flow through the puncture opening when the base frame is in the deployed configuration.

    Abstract translation: 用于密封穿刺开口的装置可以包括具有输送构型的基座框架,其中底架缩回以具有相对较小的总体轮廓,以及展开构型,其中底架被延伸以具有相对较大的整体轮廓。 基座的尺寸设计成在展开构型中接合血管壁的内表面。 密封部分联接到基部框架,密封部分具有初始构造,其中密封部分允许流体流动,以及阻挡构造,其中密封部分防止流体流动。 阻挡构造中的密封部分的尺寸被设计成当底架处于展开构型时阻止穿过穿刺孔的流体流动。

    Magnetic Device To Control Obesity And Related Method Of Use
    15.
    发明申请
    Magnetic Device To Control Obesity And Related Method Of Use 审中-公开
    控制肥胖的磁性装置及相关使用方法

    公开(公告)号:US20160030220A1

    公开(公告)日:2016-02-04

    申请号:US14884379

    申请日:2015-10-15

    Inventor: Jan Weber

    Abstract: A medical device includes an outer shell defining a cavity, wherein the shell is movable between a deformed and unstressed state, a magnet disposed within the cavity, and a filler material carried within the cavity conforming to the interior shape of the shell in the unstressed state and being capable of holding its shape in the deformed state. The filler material converts from the deformed state to the unstressed state at a temperature not greater than human body temperature.

    Abstract translation: 医疗装置包括限定空腔的外壳,其中壳体可在变形和不受应力状态之间移动,设置在空腔内的磁体和在空腔内承载的填充材料,其符合不受应力状态的壳体的内部形状 并且能够将其形状保持在变形状态。 填充材料在不大于人体温度的温度下从变形状态转变为不受应力状态。

    Medical devices and related methods

    公开(公告)号:US12213648B2

    公开(公告)日:2025-02-04

    申请号:US17663933

    申请日:2022-05-18

    Abstract: A medical device includes a handle including an axle, a device shaft extending from the handle to a distal end, and a control device. The control device is coupled to the handle, and the control device includes a knob. The knob is rotatable relative to the handle. The control device also includes a control shaft extending from the knob, at least one spring clutch including two legs, and a spool. The spool is rotatable relative to the axle. The control device also includes one or more wires coupled to the spool. Rotation of the knob is configured to rotate the control shaft, causing the at least one spring clutch to loosen, the spool to rotate, and the one or more wires to move.

    Prosthetic valves, valve leaflets and related methods

    公开(公告)号:US11559394B2

    公开(公告)日:2023-01-24

    申请号:US16526150

    申请日:2019-07-30

    Abstract: Examples herein include prosthetic valves, valve leaflets and related methods. In an example, a prosthetic valve is included having a plurality of leaflets. The leaflets can each have a root portion and an edge portion substantially opposite the root portion and movable relative to the root portion. The leaflets can include a fibrous matrix including polymeric fibers having an average diameter of about 10 nanometers to about 10 micrometers. A coating can surround the polymeric fibers within the fibrous matrix. The coating can have a thickness of about 3 to about 30 nanometers. The coating can be formed of a material selected from the group consisting of a metal oxide, a nitride, a carbide, a sulfide, or fluoride. In an example, a method of making a valve is included. Other examples are also included herein.

    Decalcifying heart valve
    18.
    发明授权

    公开(公告)号:US11357623B2

    公开(公告)日:2022-06-14

    申请号:US15954845

    申请日:2018-04-17

    Inventor: Jan Weber

    Abstract: Vascular valve systems for treating calcified vascular vessel valves by delivery of one or more calcium chelating agents are described. The vascular valve systems can include an expandable stent, a valve, and a material layer. The material layer includes a hydrogel, calcium chelating agent, and an acidifying agent. Methods of making the vascular valve systems are also described.

    MULTIPLE PUMP SYSTEM FOR INFLATABLE PENILE PROSTHESIS

    公开(公告)号:US20210393406A1

    公开(公告)日:2021-12-23

    申请号:US17447112

    申请日:2021-09-08

    Abstract: According to an aspect, an inflatable penile prosthesis includes a fluid reservoir configured to hold fluid, an inflatable member, and a pump assembly configured to transfer the fluid from the fluid reservoir to the inflatable member during an inflation cycle. The pump assembly includes a first pump configured to inject the fluid into the inflatable member according to a first flow rate, and a second pump configured to inject fluid into the inflatable member according to a second flow rate, where the second flow rate is less than the first flow rate.

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