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    Antibodies Against Bacterial Antigens and Their Use in the Generation of Immune Responses Against Apoptotic Cells
    11.
    发明申请
    Antibodies Against Bacterial Antigens and Their Use in the Generation of Immune Responses Against Apoptotic Cells 审中-公开
    抗细菌抗原的抗体及其在产生针对凋亡细胞的免疫应答中的应用

    公开(公告)号：US20070258897A1

    公开(公告)日：2007-11-08

    申请号：US11630444

    申请日：2005-06-23

    Applicant: Andrew Devitt ,  Christopher Gregory

    Inventor： Andrew Devitt ,  Christopher Gregory

    IPC: A61K39/395 ,  A61K48/00 ,  A61P43/00 ,  G01N33/53 ,  G01N33/567 ,  G01N33/574

    CPC classification number: C07K16/30 ,  A61K2039/505 ,  C07K16/1203 ,  C07K2317/82

    Abstract: The present invention provides a method of enhancing an immune response to apoptotic cells, the method comprising administration of a specific binding member which specifically binds to a microbial antigen. Also provided are pharmaceutical compositions comprising such antibodies and assays to identify specific binding members capable of enhancing an immune response to apoptotic cells. Also described are methods for the treatment of cancer using antibodies which bind to an apoptotic cell intracellular antigen.

    Abstract translation: 本发明提供增强对凋亡细胞的免疫应答的方法，所述方法包括施用特异性结合微生物抗原的特异性结合成员。 还提供了包含这种抗体和测定以鉴定能够增强对凋亡细胞的免疫应答的特异性结合成员的药物组合物。 还描述了使用结合凋亡细胞细胞内抗原的抗体治疗癌症的方法。

    Stoma plug
    13.
    发明申请
    Stoma plug 有权
    口袋塞

    公开(公告)号：US20060058576A1

    公开(公告)日：2006-03-16

    申请号：US10939846

    申请日：2004-09-13

    Applicant: Geraint Davies ,  John Cline ,  Christopher Gregory ,  Alan Cucknell ,  Julian Scarfe ,  Pete Cauwood

    Inventor： Geraint Davies ,  John Cline ,  Christopher Gregory ,  Alan Cucknell ,  Julian Scarfe ,  Pete Cauwood

    IPC: A61F2/02

    CPC classification number: A61F5/445

    Abstract: An ostomy plug is described comprising first and second chambers having adjacent ends coupled to, and in fluid communication with, each other. The first chamber may be for insertion into a stoma. The second chamber may contain fluid for inflating the first chamber when the second chamber is squeezed or otherwise compressed. The plug may have a figure-of-eight configuration. The plug may be configured to permit venting of flatus while obstructing escape of other body waste from the stoma. The plug may incorporate an insertion aid for aiding insertion into a stoma. The plug may also incorporate a device for regulating the inflation pressure of the fluid to avoid undesirably high inflation pressures in the stoma.

    Abstract translation: 描述了一种造口术塞子，其包括具有彼此联接并彼此流体连通的相邻端部的第一和第二腔室。 第一腔可以插入造口。 当第二室被挤压或以其它方式被压缩时，第二室可以包含用于使第一室膨胀的流体。 插头可能具有八位配置。 塞子可以被配置为允许排气，同时阻止其他身体废物从造口排出。 插塞可以包括用于辅助插入造口的插入辅助件。 插塞还可以包括用于调节流体的充气压力的装置，以避免造口中不期望的高的充气压力。

    Operational frequency range of latch circuits
    14.
    发明申请
    Operational frequency range of latch circuits 失效
    锁存电路的工作频率范围

    公开(公告)号：US20050280460A1

    公开(公告)日：2005-12-22

    申请号：US10502438

    申请日：2004-06-18

    Applicant: Christopher Gregory

    Inventor： Christopher Gregory

    IPC: H03K3/012 ,  H03K3/2885 ,  H03K3/356

    CPC classification number: H03K3/012 ,  H03K3/2885

    Abstract: Described herein is a latch circuit (110) which has an improved maximum toggle rate or frequency. The latch circuit (110) comprises a first portion (116) and a second portion (62) in which input clock signals (52, 54) are applied to respective input transistors (118, 78). The input transistor (118) for the first portion (116) has an emitter area which is double that of the input transistor (78) for the second portion (62). This ‘imbalance’ between the two input transistors (118, 78) provides an increase in the ‘hold period/follow period’ ratio such that it is greater than 1, the self-resonance of the latch circuit (110) and also maximum toggle rate or frequency.

    Abstract translation: 这里描述的是具有改进的最大切换速率或频率的锁存电路（110）。 锁存电路（110）包括第一部分（116）和第二部分（62），其中将输入时钟信号（52,54）施加到相应的输入晶体管（118,78）。 用于第一部分（116）的输入晶体管（118）具有与用于第二部分（62）的输入晶体管（78）的两倍的发射极面积。 两个输入晶体管（118,78）之间的“不平衡”提供了“保持周期/跟随周期”比例的增加，使得其大于1，锁存电路（110）的自谐振以及最大切换 速率或频率。

    System and method for early breast cancer detection using electrical property enhanced tomography
    15.
    发明授权
    System and method for early breast cancer detection using electrical property enhanced tomography 有权
    使用电性能增强断层扫描的早期乳腺癌检测的系统和方法

    公开(公告)号：US09066671B2

    公开(公告)日：2015-06-30

    申请号：US12425567

    申请日：2009-04-17

    Applicant: William D. Gregory ,  Christopher Gregory

    Inventor： William D. Gregory ,  Christopher Gregory

    IPC: A61B5/05 ,  A61B5/053 ,  A61B5/00 ,  A61B6/00

    CPC classification number: A61B5/0536 ,  A61B5/053 ,  A61B5/4312 ,  A61B6/502 ,  A61B2562/0209 ,  A61B2562/046

    Abstract: A system and method for detecting cancerous tissue in a subject is provided. More specifically, the present invention provides a system and method for non-invasively identifying cancerous regions in breast tissue. The system includes a sensor system, a drive system, and a processor. The sensor system includes a sensor plate and, similarly, the drive system includes a drive plate. A time-varying voltage is applied to the drive plate and induced currents are subsequently measured by the sensor plate. Signals indicative of an induced current are then acquired and analyzed by the processor to determine the spatial location of anomalous regions. Subsequently, the anomalous regions are characterized as either cancerous or non-cancerous.

    Abstract translation: 提供了一种用于检测受试者中的癌组织的系统和方法。 更具体地，本发明提供了用于非侵入性地鉴定乳腺组织中的癌性区域的系统和方法。 该系统包括传感器系统，驱动系统和处理器。 传感器系统包括传感器板，并且类似地，驱动系统包括驱动板。 时变电压被施加到驱动板，感应电流随后由传感器板测量。 然后由处理器获取并分析指示感应电流的信号，以确定异常区域的空间位置。 随后，异常区域被表征为癌性或非癌性。

    Joint Compound Application Assembly
    19.
    发明申请
    Joint Compound Application Assembly 有权

    公开(公告)号：US20250129619A1

    公开(公告)日：2025-04-24

    申请号：US18382488

    申请日：2023-10-21

    Applicant: Christopher Gregory

    Inventor： Christopher Gregory

    IPC: E04F21/165 ,  B05C17/02 ,  B62B3/00

    Abstract: A joint compound application assembly for evenly applying joint compound to drywall includes a cart and a box disposed on the cart. A pan is positionable in the box thereby facilitating the box to restrain the pan and the pan can contain joint compound. A roller mount has a first engagement element fixed to the roller mount and a second engagement element movably attached to the roller mount. The second engagement element is positionable in an engaging position or a disengaging position. A pair of rollers is provided and a respective one of the pair of rollers is rotatably attachable to the first engagement element and the second engagement element. In this way the respective roller can apply the joint compound to a wall.

    Cell separation technique
    20.
    发明授权
    Cell separation technique 有权
    细胞分离技术

    公开(公告)号：US09435790B2

    公开(公告)日：2016-09-06

    申请号：US13142046

    申请日：2009-12-23

    Applicant: Christopher Gregory ,  John Pound

    Inventor： Christopher Gregory ,  John Pound

    IPC: G01N33/50

    CPC classification number: G01N33/5032 ,  G01N2400/22

    Abstract: In a first aspect, the present invention provides a method of removing non-viable cells from a cell population, said method comprising contacting a cell population with a compound under conditions suitable to permit binding between the compound and any non-viable cells present in the cell culture and removing at least some of the compound from said cell population. The invention further provides compositions suitable for use in these methods, further uses of such compositions and various other systems and kits.

    Abstract translation: 在第一方面，本发明提供从细胞群体中除去非活细胞的方法，所述方法包括使细胞群与化合物在适于允许化合物与存在于细胞中的任何非存活细胞之间结合的条件下接触化合物 细胞培养并从所述细胞群中除去至少一些化合物。 本发明还提供适用于这些方法的组合物，这种组合物和各种其它体系和试剂盒的进一步用途。

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