公开(公告)号：US20100150341A1

公开(公告)日：2010-06-17

申请号：US12336568

申请日：2008-12-17

申请人： David Dodgson ,  Joseph Neill ,  Ralph Farina ,  Edward Chin ,  Albert French ,  Scott Summers ,  Robert Johnson

发明人： David Dodgson ,  Joseph Neill ,  Ralph Farina ,  Edward Chin ,  Albert French ,  Scott Summers ,  Robert Johnson

IPC分类号： H04L9/28 ,  H04L9/00 ,  H04L9/06

CPC分类号： G06F21/805 ,  H04L9/085 ,  H04L9/0894

摘要： Methods and systems for securing data in a data storage network are disclosed. One method includes receiving at a secure storage appliance a block of data for storage on a volume, the volume associated with a plurality of shares distributed across a plurality of physical storage devices. The method further includes cryptographically splitting the block of data received by the secure storage appliance into a plurality of secondary data blocks, and cryptographically splitting the session key into a plurality of session key fragments. The method further includes encrypting each of the plurality of secondary data blocks with a different session key, each session key associated with at least one of the plurality of shares, and encrypting each of the plurality of session key fragments with a workgroup key associated with a source of the block of data.

摘要翻译： 公开了用于在数据存储网络中保护数据的方法和系统。 一种方法包括在安全存储设备处接收用于存储在卷上的数据块，所述数据块与多个物理存储设备上分布的多个共享相关联。 该方法还包括将由安全存储设备接收的数据块加密地分割成多个辅助数据块，以及将会话密钥加密地分割成多个会话密钥片段。 该方法还包括用不同的会话密钥加密多个辅助数据块中的每一个，每个会话密钥与多个共享中的至少一个共享相关联，并且利用与该多个会话密钥相关联的工作组密钥加密每个会话密钥片段 源数据块。

公开(公告)号：US20090240090A1

公开(公告)日：2009-09-24

申请号：US12404130

申请日：2009-03-13

申请人： Daniel C. Merkel ,  Hsueh Sung Tung ,  Konstantin A. Pokrovski ,  Selma Bektesevic ,  Robert Johnson ,  Haiyou Wang

发明人： Daniel C. Merkel ,  Hsueh Sung Tung ,  Konstantin A. Pokrovski ,  Selma Bektesevic ,  Robert Johnson ,  Haiyou Wang

IPC分类号： C07C17/20

CPC分类号： C07C21/18 ,  C01B7/035 ,  C01B7/0706 ,  C01B7/195 ,  C07C17/087 ,  C07C17/10 ,  C07C17/206 ,  C07C17/25 ,  C07C17/383 ,  Y02P20/125 ,  Y02P20/582 ,  C07C19/10

摘要： A method for preparing 2,3,3,3-tetrafluoroprop-1-ene comprising (a) providing a starting composition comprising at least one compound having a structure selected from Formulae I, II and III: CX2═CCl—CH2X  (Formula I) CX3—CCl═CH2  (Formula II) CX3—CHCl—CH2X  (Formula III) wherein X is independently selected from F, Cl, Br, and I, provided that at least one X is not fluorine; (b) contacting said starting composition with a first fluorinating agent to produce a first intermediate composition comprising 2-chloro-3,3,3-trifluoropropene and a first chlorine-containing byproduct; (c) contacting said first intermediate composition with a second fluorinating agent to produce a second intermediate composition comprising 2-chloro-1,1,1,2-tetrafluoropropane and a second chlorine-containing byproduct; and (d) catalytically dehydrochlorinating at least a portion of said 2-chloro-1,1,1,2-tetrafluoropropane to produce a reaction product comprising 2,3,3,3-tetrafluoroprop-1-ene.

摘要翻译： 一种制备2,3,3,3-四氟丙-1-烯的方法，包括（a）提供起始组合物，其包含至少一种具有选自式I，II和III的结构的化合物： =“直线公式”end =“lead”？> CX2-CCl-CH2X（式I）<？in-line-formula description =“In-line Formulas”end =“tail”？> <？in-line -formulae description =“In-line Formulas”end =“lead”？> CX3-CCl-CH2（式II）<？in-line-formula description =“In-line Formulas”end =“tail”？> in-line-formula description =“In-line Formulas”end =“lead”？> CX3-CHCl-CH2X（式III）<？in-line-formula description =“In-line Formulas”end =“tail”？ >其中X独立地选自F，Cl，Br和I，条件是至少一个X不是氟; （b）使所述起始组合物与第一氟化剂接触以产生包含2-氯-3,3,3-三氟丙烯和第一含氯副产物的第一中间体组合物; （c）使所述第一中间体组合物与第二氟化剂接触以产生包含2-氯-1,1,1,2-四氟丙烷和第二含氯副产物的第二中间体组合物; 和（d）将至少一部分所述2-氯-1,1,1,2-四氟丙烷催化脱氯化氢以产生包含2,3,3,3-四氟丙-1-烯的反应产物。

公开(公告)号：US20090197852A9

公开(公告)日：2009-08-06

申请号：US11542960

申请日：2006-10-03

申请人： Robert Johnson ,  Alison Hannah ,  Gillian Cropp ,  Yiqing Zhou ,  J. Sherrill

发明人： Robert Johnson ,  Alison Hannah ,  Gillian Cropp ,  Yiqing Zhou ,  J. Sherrill

IPC分类号： A61K31/395

CPC分类号： A61K31/395 ,  A61K39/39558 ,  A61K2039/545 ,  C07K16/32 ,  A61K2300/00

摘要： A method for treating a breast cancer in a subject by administering 17-allylamino-17-demethoxy-geldanamycin (17-AAG) or 17-amino-17-demethoxygeldanamycin (17-AG), or a prodrug of either 17-AAG or 17-AG, in combination with a HER2 inhibitor.

摘要翻译： 通过给予17-烯丙基氨基-17-去甲氧基 - 格尔德霉素（17-AAG）或17-氨基-17-去甲氧基格尔德霉素（17-AG）或17-AAG或17 -AG，与HER2抑制剂组合。

公开(公告)号：US20080171924A9

公开(公告)日：2008-07-17

申请号：US10852415

申请日：2004-05-24

申请人： Trent Ridder ,  John Maynard ,  Russell Abbink ,  Robert Johnson ,  Edward Hull ,  Andrew Meigs ,  Alan Ross ,  Dashiell Birnkrant

发明人： Trent Ridder ,  John Maynard ,  Russell Abbink ,  Robert Johnson ,  Edward Hull ,  Andrew Meigs ,  Alan Ross ,  Dashiell Birnkrant

IPC分类号： A61B5/00

CPC分类号： A61B5/1455 ,  A61B5/0059 ,  A61B5/0075 ,  A61B5/14546

摘要： An apparatus and method for non-invasive determination of attributes of human tissue by quantitative infrared spectroscopy. The system includes subsystems optimized to contend with the complexities of the tissue spectrum, high signal-to-noise ratio and photometric accuracy requirements, tissue sampling errors, calibration maintenance problems, and calibration transfer problems. The subsystems include an illumination subsystem, a tissue sampling subsystem, a spectrometer subsystem, a data acquisition subsystem, and a processing subsystem. The invention is applicable, as examples, to determining the concentration or change of concentration of alcohol in human tissue.

摘要翻译： 一种用于通过定量红外光谱非侵入式确定人体组织属性的装置和方法。 该系统包括优化的子系统，以应对组织光谱的复杂性，高信噪比和光度精度要求，组织采样误差，校准维护问题和校准转移问题。 子系统包括照明子系统，组织采样子系统，光谱仪子系统，数据采集子系统和处理子系统。 作为实例，本发明可用于确定人体组织中酒精浓度或浓度的变化。

公开(公告)号：US20070264206A1

公开(公告)日：2007-11-15

申请号：US11302992

申请日：2006-05-11

申请人： Rameshbabu Boga ,  Robert Johnson

发明人： Rameshbabu Boga ,  Robert Johnson

IPC分类号： A61K8/46 ,  A61K31/685

CPC分类号： A61K9/127 ,  A61K31/565 ,  A61K31/685 ,  A61K2300/00

摘要： A mucosal formulation for administration to mucosal membranes, such as in the mouth, nasal passage, stomach, vagina, etc., is disclosed. The mucosal formulation contains a lipid-pharmaceutical agent complex formed from phospholipids possessing a hydrophobic moiety that orients into a hydrophobic phase and a polar head moiety that orients towards the aqueous phase (i.e., “amphipathic” lipids). When placed in an aqueous medium (e.g., vaginal fluid), the phospholipids form liposomes or other small lipid vesicles (e.g., micelles) that may then be used to deliver pharmaceutical agents into a living organism.

摘要翻译： 公开了用于施用于粘膜的粘膜制剂，例如在口腔，鼻腔，胃，阴道等中。 粘膜制剂包含由具有疏水部分的磷脂形成的脂质 - 药剂复合物，所述疏水部分定位于疏水相和朝向水相定向的极性头部分（即“两亲性”脂质）。 当放置在水性介质（例如阴道液）中时，磷脂形成脂质体或其它小脂质囊泡（例如胶束），然后可以将其用于将药剂递送到生物体内。

公开(公告)号：US20070217128A1

公开(公告)日：2007-09-20

申请号：US11378054

申请日：2006-03-17

申请人： Robert Johnson

发明人： Robert Johnson

IPC分类号： H02B1/26

CPC分类号： H05K7/1492 ,  H02J9/06

摘要： A modular electronic equipment system includes a plurality of equipment racks. Each equipment rack includes a equipment rack frame configured to receive and support electronic equipment, a power input cable having a first end fixedly attached to the equipment rack frame and configured to be electrically coupled to electronic equipment supported by the equipment rack frame to provide power thereto and a first connector attached to a second end of the power input cable. The system further includes a power distribution rack. The power distribution rack includes a power distribution rack frame and a plurality of second connectors supported by the power distribution rack frame and configured to pluggably mate with the first connectors of the equipment racks.

摘要翻译： 模块化电子设备系统包括多个设备机架。 每个设备机架包括被配置为接收和支持电子设备的设备机架框架，电源输入电缆，其具有固定地连接到设备机架框架的第一端，并且被配置为电耦合到由设备机架框架支撑以向其供电的电子设备 以及附接到所述电力输入电缆的第二端的第一连接器。 该系统还包括配电架。 配电架包括配电架框架和由配电架框架支撑并被配置为可插拔地与设备机架的第一连接器配合的多个第二连接器。

公开(公告)号：US20070164156A1

公开(公告)日：2007-07-19

申请号：US11709548

申请日：2007-02-22

申请人： James Henley ,  Robert Johnson ,  Darrel Santala ,  Samuel Feist ,  Trevor Laib ,  Bradley Mitchell ,  Kevin Callahan

发明人： James Henley ,  Robert Johnson ,  Darrel Santala ,  Samuel Feist ,  Trevor Laib ,  Bradley Mitchell ,  Kevin Callahan

IPC分类号： B64D11/06

CPC分类号： B64D11/0624 ,  B64D11/06 ,  B64D2221/00 ,  H01R4/26 ,  H01R25/14 ,  H02G3/00

摘要： A method of providing power and/or data to a seat in a seating area. A power distribution system having a continuous power bus is used to supply power and/or data to seats in a mobile platform or fixed structure. The power distribution system generally includes a bus strip that, in a mobile platform, extends along a length of a passenger cabin and a connector operable to provide a connection between the bus strip and the passenger seats. Power and/or data can be transmitted between the bus strip and the passenger seats, via the connector, at any point along the bus strip, thus eliminating the need to run separate connections between the power and/or data source and each seat.

摘要翻译： 向休息区的座椅提供动力和/或数据的方法。 具有连续功率总线的配电系统用于向移动平台或固定结构中的座椅供电和/或数据。 配电系统通常包括总线条，其在移动平台中沿着客舱的长度延伸，以及可操作以在总线带和乘客座之间提供连接的连接器。 电源和/或数据可以在总线条和乘客座位之间通过连接器沿着总线条的任何点传输，因此不需要在电源和/或数据源与每个座位之间运行单独的连接。

公开(公告)号：US20070153553A1

公开(公告)日：2007-07-05

申请号：US11323627

申请日：2005-12-30

申请人： George Cebry ,  Ernest Graetz ,  Robert Johnson ,  Robert Tomlinson

发明人： George Cebry ,  Ernest Graetz ,  Robert Johnson ,  Robert Tomlinson

IPC分类号： H02M3/335

CPC分类号： H02M3/33592 ,  H02M2001/0048 ,  Y02B70/1475 ,  Y02B70/1491

摘要： A DC-to-DC converter comprises a converter section and a controller section. The converter section comprises a primary section and a secondary section. The primary and secondary section includes MOSFET switches. The controller section is coupled to the converter section and comprises a pulse width modulation (PWM) section and a delay section. The PWM section comprises an error amplifier configured to generate an error signal representative of a variance between an output voltage of the converter section and a reference voltage and a PWM configured to produce a PWM signal based on the error signal. The delay section comprises of delay circuits configured to generate delayed output signals from the PWM signal and power switching device drivers coupled to the delay circuits and configured to receive the delay output signals and generate a controlled signals to control the on/off state of the MOSFET switches.

摘要翻译： DC-DC转换器包括转换器部分和控制器部分。 转换器部分包括初级部分和次级部分。 初级和次级部分包括MOSFET开关。 控制器部分耦合到转换器部分，并且包括脉宽调制（PWM）部分和延迟部分。 PWM部分包括误差放大器，其被配置为产生代表转换器部分的输出电压和参考电压之间的差异的误差信号，以及配置为基于误差信号产生PWM信号的PWM。 延迟部分包括被配置为从PWM信号产生延迟的输出信号的延迟电路和耦合到延迟电路的功率开关器件驱动器，并且被配置为接收延迟输出信号并产生受控信号以控制MOSFET的导通/截止状态 开关。

公开(公告)号：US20070099154A1

公开(公告)日：2007-05-03

申请号：US11266452

申请日：2005-11-03

申请人： Robert Johnson

发明人： Robert Johnson

IPC分类号： A61C1/00 ,  A61C5/00

CPC分类号： A61C19/06 ,  A61C1/0046 ,  A61C1/088 ,  A61C3/00 ,  A61C3/02 ,  A61N5/0603 ,  A61N2005/0606 ,  A61N2005/0644 ,  A61N2005/0661

摘要： A method of treating a dental patient includes applying ultraviolet C radiation to the mouth of the patient for a time and at a proximity and intensity sufficient to have a bacteriocidal effect. With this method, the risk of bacterial infection to both the patient and the dentist/oral surgeon can be reduced.

摘要翻译： 一种治疗牙科患者的方法包括将紫外线C辐射施加到患者的口腔上一段时间，接近度和强度足以具有杀菌作用。 通过这种方法，可以减少对患者和牙医/口腔外科医生的细菌感染的风险。

公开(公告)号：US20070088205A1

公开(公告)日：2007-04-19

申请号：US11561380

申请日：2006-11-17

申请人： Edward Hull ,  Marwood Ediger ,  Christopher Brown ,  John Maynard ,  Robert Johnson

发明人： Edward Hull ,  Marwood Ediger ,  Christopher Brown ,  John Maynard ,  Robert Johnson

IPC分类号： A61B5/00

CPC分类号： A61B5/1455 ,  A61B5/0059 ,  A61B5/0064 ,  A61B5/0066 ,  A61B5/0068 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/14532 ,  A61B5/412 ,  A61B5/441

摘要： A method of detefnnining a measure of a tissue state (e.g., glycation end-product or disease state) in an individual. A portion of the tissue of the individual is illuminated with excitation light, then light emitted by the tissue due to fluorescence of a chemical with the tissue responsive to the excitation light is detected. The detected light can be combined with a model relating fluorescence with a measure of tissue state to determine a tissue state. The invention can comprise single wavelength excitation light, scanning of excitation light (illuminating the tissue at a plurality of waveliengths), detection at a single wavelength, scanning of detection wavelengths (detecting emitted light at a plurality of wavelengths), and combinations thereof. The invention also can comprise correction techniques that reduce determination errors due to detection of light other than that from fluorescence of a chemical in the tissue. For example, the reflectance of the tissue can lead to errors if appropriate correction is not employed. The invention can also comprise a variety of models relating fluorescence to a measure of tissue state, including a variety of methods for generating such models. Other biologic information can be used in combination with the fluorescence properties to aid in the determination of a measure of tissue state. The invention also comprises apparatuses suitable for carrying out the method, including appropriate light sources, detectors, and models (for example, implemented on computers) used to relate detected fluorescence and a measure of tissue state.

摘要翻译： 确定个体中组织状态（例如，糖基化终产物或疾病状态）的量度的方法。 用激发光照射个体组织的一部分，然后检测由组织响应于激发光的化学物质的荧光而由组织发出的光。 检测到的光可以与将荧光与组织状态的测量相关联的模型组合以确定组织状态。 本发明可以包括单波长激发光，激发光的扫描（以多个波长照射组织），单个波长的检测，检测波长的扫描（检测多个波长的发射光）及其组合。 本发明还可以包括校正技术，其减少由于检测到除了组织中的化学物质的荧光以外的光的测定误差。 例如，如果不采用适当的校正，组织的反射率可能导致错误。 本发明还可以包括将荧光与组织状态的测量相关联的各种模型，包括用于产生这种模型的各种方法。 其他生物信息可与荧光性质结合使用，有助于测定组织状态。 本发明还包括适于执行该方法的装置，包括用于检测荧光和组织状态测量的适当的光源，检测器和模型（例如，在计算机上实现）。