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公开(公告)号:US20160215306A1
公开(公告)日:2016-07-28
申请号:US14915208
申请日:2014-08-15
Applicant: EVOLVA SA
Inventor: Richard Jan Steven Baerends , Ernesto Simon , Jean Phillippe Meyer , Carlos Casado Vazquez
CPC classification number: C12P7/22 , C12N9/1007 , C12N9/1051 , C12P7/62 , C12P19/44 , C12Y201/00 , C12Y201/01 , C12Y204/00
Abstract: Methods for producing glycosylated and methylated resveratrol in a genetically engineered cell, by bioconversion, and in vitro are disclosed herein.
Abstract translation: 本文公开了通过生物转化和体外在遗传工程细胞中产生糖基化和甲基化的白藜芦醇的方法。
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公开(公告)号:US20230279459A1
公开(公告)日:2023-09-07
申请号:US18052477
申请日:2022-11-03
Applicant: EVOLVA SA
Inventor: Michael Dalgaard Mikkelsen , Jorgen Hansen , Ernesto Simon , Federico Brianza , Angelika Semmler , Kim Olsson , Simon Carlsen , Louis Düring , Alexei Ouspenski , Paula Hicks
CPC classification number: C12P19/56 , C12N9/0071 , C12N9/90 , A23L2/60 , C12Y204/01 , C12N9/1051 , C12N9/1081 , C12N9/1085 , C12N15/81 , A23L27/36 , C12Y204/99 , A23V2002/00
Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.
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公开(公告)号:US11530431B2
公开(公告)日:2022-12-20
申请号:US16799541
申请日:2020-02-24
Applicant: EVOLVA SA
Inventor: Michael Dalgaard Mikkelsen , Jorgen Hansen , Ernesto Simon , Federico Brianza , Angelika Semmler , Kim Olsson , Simon Carlsen , Louis Düring , Alexei Ouspenski , Paula Hicks
Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.
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公开(公告)号:US20220228185A1
公开(公告)日:2022-07-21
申请号:US17471615
申请日:2021-09-10
Applicant: EVOLVA SA
Inventor: Jens Houghton-Larsen , Paula Hicks , Michael Naesby , Thomas Tange Ostergaard , Jorgen Hansen , Michael Mikkelsen Dalgaard , Esben Hansen Halkjaer , Ernesto Simon , Sabina De Andrade Periera Tavares
IPC: C12P19/56 , C12N9/88 , C12N9/06 , C12N9/02 , C12N9/10 , C12N9/90 , C12N15/81 , C12N15/82 , C12P19/44 , C12N15/63
Abstract: Recombiant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorgansims, plants, or plant cells can produce steviol glycosides, e.g., Rebaudioside A and/or Rebaudioside D, which can be used as natural sweeteners in food products and dietary supplements.
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公开(公告)号:US20200308617A1
公开(公告)日:2020-10-01
申请号:US16799541
申请日:2020-02-24
Applicant: EVOLVA SA
Inventor: Michael Dalgaard Mikkelsen , Jorgen Hansen , Ernesto Simon , Federico Brianza , Angelika Semmler , Kim Olsson , Simon Carlsen , Louis Düring , Alexei Ouspenski , Paula Hicks
Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.
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公开(公告)号:US10017804B2
公开(公告)日:2018-07-10
申请号:US14764898
申请日:2014-02-11
Applicant: Evolva SA
Inventor: Ernesto Simon , Iben Nordmark Anderson , Michael Dalgaard Mikkelsen , Jorgen Hansen , Veronique Douchin
CPC classification number: C12P19/56 , C07K14/395 , C12N9/0042 , C12N9/0073 , C12N9/1048 , C12N9/1051 , C12N9/1062 , C12N9/1085 , C12N9/88 , C12N9/90 , C12P15/00 , C12Y106/02004 , C12Y114/13078 , C12Y204/00 , C12Y204/01013 , C12Y204/01035 , C12Y205/01029 , C12Y402/03 , C12Y402/03019 , C12Y505/01013
Abstract: Recombinant microorganisms are disclosed that produce steviol glycosides and have altered expression of one or more endogenous transporter or transcription factor genes, or that overexpress one or more heterologous transporters, leading to increased excretion of steviol glycosides of interest.
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公开(公告)号:US20240026409A1
公开(公告)日:2024-01-25
申请号:US18450950
申请日:2023-08-16
Applicant: EVOLVA SA
Inventor: Kim Olsson , Ernesto Simon , Michael Dalgaard Mikkelsen , Simon Carlsen , Veronique Douchin , Swee Chuang Lim , Louis During
IPC: C12P19/56 , C12N9/10 , C12P15/00 , C07H15/256
CPC classification number: C12P19/56 , C12N9/1051 , C12Y204/01 , C12P15/00 , C07H15/256
Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
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公开(公告)号:US20230407360A1
公开(公告)日:2023-12-21
申请号:US18132027
申请日:2023-04-07
Applicant: EVOLVA SA
Inventor: Jens Houghton-Larsen , Paula Hicks , Michael Naesby , Thomas Tange Ostergaard , Jorgen Hansen , Michael Mikkelsen Dalgaard , Esben Hansen-Halkjaer , Ernesto Simon , Sabina Tavares
IPC: C12P19/56 , C12N9/88 , C12N9/06 , C12N9/02 , C12N9/10 , C12N9/90 , C12N15/81 , C12N15/82 , C12P19/44 , C12N15/63
CPC classification number: C12P19/56 , C12N9/88 , C12N9/0032 , C12N9/0073 , C12N9/0071 , C12N9/1051 , C12N9/1085 , C12N9/90 , C12N15/81 , C12N15/8243 , C12P19/44 , C12N15/63 , Y02P20/52
Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol glycosides, e.g., Rebaudioside A and/or Rebaudioside D, which can be used as natural sweeteners in food products and dietary supplements.
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公开(公告)号:US11807888B2
公开(公告)日:2023-11-07
申请号:US17243904
申请日:2021-04-29
Applicant: EVOLVA SA
Inventor: Kim Olsson , Ernesto Simon , Michael Dalgaard Mikkelsen , Simon Carlsen , Veronique Douchin , Swee Chuang Lim , Louis During
IPC: C12P19/56 , C12N9/10 , C12P15/00 , C07H15/256
CPC classification number: C12P19/56 , C07H15/256 , C12N9/1051 , C12P15/00 , C12Y204/01
Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
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公开(公告)号:US20230033436A1
公开(公告)日:2023-02-02
申请号:US17243904
申请日:2021-04-29
Applicant: EVOLVA SA
Inventor: Kim Olsson , Ernesto Simon , Michael Dalgaard Mikkelsen , Simon Carlsen , Veronique Douchin , Swee Chuang Lim , Louis During
IPC: C12P19/56 , C12N9/10 , C12P15/00 , C07H15/256
Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
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