-
公开(公告)号:US20170274092A1
公开(公告)日:2017-09-28
申请号:US15438418
申请日:2017-02-21
申请人: GENENTECH, INC.
发明人: Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC分类号: A61K47/48 , C07K16/00 , A61K39/395 , C07K16/32 , A61K31/5517 , C07K19/00 , C07D487/16
CPC分类号: A61K31/5517 , A61K39/39558 , A61K47/6803 , A61K47/6855 , A61K47/6869 , C07K16/005 , C07K16/32 , C07K2317/24 , C07K2317/92
摘要: The invention provides immunoconjugates comprising anti-HER2 antibodies and methods of using the same.
-
公开(公告)号:US11732054B2
公开(公告)日:2023-08-22
申请号:US16790656
申请日:2020-02-13
申请人: Genentech, Inc.
发明人: Xiaocheng Chen , Mark S. Dennis , Allen J. Ebens, Jr. , Teemu T. Junttila , Robert F. Kelley , Mary A. Mathieu
IPC分类号: C07K16/28 , C07K16/32 , A61K39/395 , C07K16/30 , A61K45/06 , A61K31/573 , A61K47/68 , A61K39/00
CPC分类号: C07K16/32 , A61K31/573 , A61K39/39558 , A61K45/06 , A61K47/6881 , C07K16/283 , C07K16/2809 , C07K16/2827 , C07K16/2863 , C07K16/2887 , C07K16/2896 , C07K16/30 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/622 , C07K2317/71 , C07K2317/73 , C07K2317/92
摘要: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
-
公开(公告)号:US10174124B2
公开(公告)日:2019-01-08
申请号:US14574132
申请日:2014-12-17
申请人: Genentech, Inc.
发明人: Xiaocheng Chen , Mark S. Dennis , Allen J. Ebens, Jr. , Robert F. Kelley , Mary A. Mathieu , Liping L. Sun
IPC分类号: A61K39/395 , C07K16/32 , C07K16/28 , C07K16/30 , A61K45/06 , A61K31/573 , A61K47/68 , A61K39/00
摘要: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
-
公开(公告)号:US20180000964A1
公开(公告)日:2018-01-04
申请号:US15618467
申请日:2017-06-09
申请人: Genentech, Inc.
发明人: Christine Tan , Ryan J. Watts , Joy Yu Zuchero , Xiaocheng Chen , Mark S. Dennis
CPC分类号: A61K47/6849 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K16/18 , C07K16/26 , C07K16/2803 , C07K16/2896 , C07K16/40 , C07K2317/31 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/92 , C12Y304/23046
摘要: The present invention relates to antibodies that bind to receptors expressed on the blood brain barrier and methods of using the same.
-
公开(公告)号:US09803191B2
公开(公告)日:2017-10-31
申请号:US13934570
申请日:2013-07-03
申请人: Genentech, Inc.
发明人: Devin Tesar , Xiaocheng Chen , Mark Dennis , Isidro Hotzel
CPC分类号: C12N15/1037 , C07K16/00 , C07K2319/02 , C07K2319/40 , C07K2319/735 , C12N15/70 , C12N15/74 , C12N15/85 , C12N2820/10 , C12N2820/55 , C12N2820/85 , C12N2830/42 , C12N2830/55 , C12N2830/85 , C12P21/02
摘要: The invention provides an expression and secretion system, and methods of using the same, for the expression and secretion of one fusion protein in prokaryotic cells and a second fusion protein in eukaryotic cells. Also provided herein are nucleic acid molecules, vectors and host cells comprising such vectors and nucleic acid molecules.
-
公开(公告)号:US09518118B2
公开(公告)日:2016-12-13
申请号:US14851001
申请日:2015-09-11
申请人: Genentech, Inc.
发明人: Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC分类号: C07K16/28 , A61K47/48 , C07K16/32 , A61K39/395 , G01N33/574
CPC分类号: C07K16/32 , A61K31/5517 , A61K31/675 , A61K31/704 , A61K39/3955 , A61K47/68 , A61K47/6809 , A61K47/6849 , A61K47/6855 , A61K47/6863 , A61K49/00 , C07K16/2863 , C07K16/3015 , C07K2317/24 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/92 , G01N33/57415 , G01N33/57446 , G01N33/57492 , G01N2333/82
摘要: The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
摘要翻译: 本发明提供抗HER2抗体和免疫缀合物及其使用方法。
-
公开(公告)号:US20150376265A1
公开(公告)日:2015-12-31
申请号:US14577991
申请日:2014-12-19
申请人: Genentech, Inc.
发明人: Xiaocheng Chen , Mark Dennis , Becket L. Feierbach , Ashley Fouts , Isidro Hotzel , Bing Li , Jo-Anne S. Hongo , Rajesh Vij
CPC分类号: C07K16/088 , A61K39/42 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K2317/24 , C07K2317/30 , C07K2317/51 , C07K2317/515 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
摘要: The invention provides compositions comprising anti-gH antibodies and anti-Complex I antibodies as well as methods of using the same.
摘要翻译: 本发明提供了包含抗-GH抗体和抗复合物I抗体的组合物以及使用该组合物的方法。
-
公开(公告)号:US20140011981A1
公开(公告)日:2014-01-09
申请号:US13934570
申请日:2013-07-03
申请人: Genentech, Inc.
发明人: Devin Tesar , Xiaocheng Chen , Mark Dennis , Isidro Hotzel
CPC分类号: C12N15/1037 , C07K16/00 , C07K2319/02 , C07K2319/40 , C07K2319/735 , C12N15/70 , C12N15/74 , C12N15/85 , C12N2820/10 , C12N2820/55 , C12N2820/85 , C12N2830/42 , C12N2830/55 , C12N2830/85 , C12P21/02
摘要: The invention provides an expression and secretion system, and methods of using the same, for the expression and secretion of one fusion protein in prokaryotic cells and a second fusion protein in eukaryotic cells. Also provided herein are nucleic acid molecules, vectors and host cells comprising such vectors and nucleic acid molecules.
摘要翻译: 本发明提供了表达和分泌系统及其使用方法,用于在真核细胞中的原核细胞和第二融合蛋白中表达和分泌一种融合蛋白。 本文还提供了包含这种载体和核酸分子的核酸分子,载体和宿主细胞。
-
公开(公告)号:US11939396B2
公开(公告)日:2024-03-26
申请号:US16916822
申请日:2020-06-30
申请人: Genentech, Inc.
发明人: Xiaocheng Chen , Mark Dennis , Janet Jackman , James T. Koerber , Mason Lu , Henry R. Maun , Kathila Rajapaksa , Saroja Ramanujan , Tracy Staton , Lawren Wu , Tangsheng Yi
IPC分类号: C07K16/40 , A61K39/395 , C07K16/24 , A61K39/00 , A61K45/06 , A61K47/10 , A61K47/18 , A61K47/22 , A61K47/26
CPC分类号: C07K16/40 , A61K39/3955 , A61K39/39591 , C07K16/244 , C12Y304/21059 , A61K2039/505 , A61K45/06 , A61K47/10 , A61K47/183 , A61K47/22 , A61K47/26 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
-
公开(公告)号:US11530275B2
公开(公告)日:2022-12-20
申请号:US16790616
申请日:2020-02-13
申请人: Genentech, Inc.
发明人: Xiaocheng Chen , Mark S. Dennis , Allen J. Ebens, Jr. , Teemu T. Junttila , Robert F. Kelley , Mary A. Mathieu
IPC分类号: C07K16/28 , C07K16/32 , A61K39/395 , C07K16/30 , A61K45/06 , A61K31/573 , A61K47/68 , A61K39/00
摘要: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
-
-
-
-
-
-
-
-
-