公开(公告)号：US20150183821A1

公开(公告)日：2015-07-02

申请号：US14645138

申请日：2015-03-11

Applicant: Genzyme Corporation

Inventor： Konstantin Konstantinov ,  Rahul Godawat ,  Veena Warikoo ,  Sujit Jain

IPC: C07K1/22 ,  C07K1/18 ,  C07K1/16 ,  B01D15/38 ,  C12N9/24 ,  B01D15/18 ,  B01D15/36 ,  B01D15/32 ,  C07K16/00 ,  C12N9/40

CPC classification number: C07K1/16 ,  B01D15/1807 ,  B01D15/1864 ,  B01D15/1871 ,  B01D15/327 ,  B01D15/34 ,  B01D15/362 ,  B01D15/363 ,  B01D15/3809 ,  B01D15/3814 ,  B01D15/422 ,  C07K1/18 ,  C07K1/22 ,  C07K1/36 ,  C07K16/00 ,  C07K2317/14 ,  C12M23/52 ,  C12M47/10 ,  C12M47/12 ,  C12N9/00 ,  C12N9/2402 ,  C12N9/2465 ,  C12P21/00 ,  C12P21/005 ,  C12Y302/01022 ,  C12Y302/01045

Abstract: Provided herein are integrated continuous biomanufacturing processes for producing a therapeutic protein drug substance. Also provided are systems that are capable of continuously producing a therapeutic protein drug substance.