公开(公告)号：US20180348106A1

公开(公告)日：2018-12-06

申请号：US15770453

申请日：2016-02-27

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Viktor SHKOLNIKOV ,  Anita ROGACS

IPC: G01N1/40 ,  B01L3/00 ,  G01N21/65

CPC classification number: G01N1/4044 ,  B01L3/5027 ,  B01L2200/0678 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2400/0478 ,  B01L2400/0487 ,  G01N21/648 ,  G01N21/658 ,  G01N2001/4088

Abstract: A sample preparation system includes a sample input, a first chamber fluidly coupled to the sample input and containing a sample preparation reagent, a second chamber containing a surface enhanced Raman spectroscopy (SERS) sensor structure and a third chamber containing a sensor preparation solution. The sample input, the first chamber and the second chamber are fluidly coupled to one another in a series and the third chamber is fluidly coupled to the third chamber outside of the series so as to sequentially direct a sample received by the sample input through the first chamber to the second chamber and out of the second chamber and so as to direct the sensor preparation solution into the second chamber following discharge of the sample out of the second chamber.

公开(公告)号：US20180321155A1

公开(公告)日：2018-11-08

申请号：US15764880

申请日：2016-01-29

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Charles M. SANTORI ,  James William STASIAK ,  Francesco AIETA ,  Anita ROGACS ,  Mineo YAMAKAWA ,  Kenneth WARD

IPC: G01N21/65

CPC classification number: G01N21/658 ,  G01N2201/0635

Abstract: Optical readers are disclosed in examples herein. An example optical reader including a light source to emit a light beam; and a spot pattern generator to receive the light beam and to generate a two-dimensional spot array from the light beam, the two-dimensional spot array to be directed toward a substrate having nanostructures, the two-dimensional spot array to be sensed to detect a presence or an absence of a substance of interest on the substrate.

公开(公告)号：US20180318833A1

公开(公告)日：2018-11-08

申请号：US15764305

申请日：2015-10-30

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Steven BARCELO ,  Ning GE ,  Anita ROGACS

IPC: B01L3/00

CPC classification number: B01L3/502707 ,  B01L3/5025 ,  B01L3/502753 ,  B01L2200/027 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2400/0415

Abstract: In an example implementation, a method of fabricating a microfluidic channel filter, includes depositing an imprintable material in a microfluidic channel, pressing an imprint stamp with a filter pattern into the imprintable material, curing the imprintable material, and removing the imprint stamp from the imprintable material.

公开(公告)号：US20210215611A1

公开(公告)日：2021-07-15

申请号：US16076077

申请日：2017-01-31

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Fausto D'APUZZO ,  Aleksandr POLYAKOV ,  Anita ROGACS

IPC: G01N21/65 ,  G01N21/552

Abstract: A surface enhanced infrared absorption stage may include a substrate, a static island extending from the substrate and a movable nano finger extending from the substrate. The static island may have a plasmonically active island cap and a dimension parallel to the substrate of at least one micrometer. The movable nano finger may be aligned with the dimension. The movable nano finger may have a plasmonicaly active finger cap closable to less than or equal to 5 nm of the island cap.

公开(公告)号：US20210208079A1

公开(公告)日：2021-07-08

申请号：US16077334

申请日：2017-07-17

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Raghuvir N. SENGUPTA ,  Anita ROGACS

IPC: G01N21/65 ,  B82Y15/00

Abstract: A surface enhanced luminescence system may include a laser and a controller to output control signals causing the laser to irradiate the pre-analyte exposed plasmonic surface while maintaining a profile of the pre-analyte exposed plasmonic surface.

公开(公告)号：US20210190694A1

公开(公告)日：2021-06-24

申请号：US16074298

申请日：2016-04-20

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Ning GE ,  Anita ROGACS ,  Viktor SHKOLNIKOV ,  Alexander GOVYADINOV

IPC: G01N21/65

Abstract: A surface enhanced Raman scattering (SERS) sensor may include a substrate, an electrically conductive layer having a first portion spaced from a second portion by a gap, an electrically resistive layer in contact with and extending between the first portion and the second portion of the electrically conductive layer to form an electrically resistive bridge across the gap that heats the nano fingers in response to electrical current flowing across the bridge from the first portion to the second portion and nano fingers extending upward from the bridge.

公开(公告)号：US20210172874A1

公开(公告)日：2021-06-10

申请号：US16076345

申请日：2017-07-20

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Milo OVERBAY ,  Anita ROGACS ,  Devin A. MOUREY

IPC: G01N21/64 ,  G01J3/44 ,  G01N21/65

Abstract: A surface enhanced luminescence analyte interrogation stage may include a substrate and an array of pillars projecting from the substrate. Each of the pillars may include a polymeric post formed from a first material and a cap on the polymeric post. The cap has a plasmonic surface and is formed from a second material different than the first. A sacrificial coating covers the cap of each of the pillars.

公开(公告)号：US20200309705A1

公开(公告)日：2020-10-01

申请号：US16628745

申请日：2017-07-13

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Caitlin DeJONG ,  Anita ROGACS

IPC: G01N21/65 ,  G01N1/40 ,  B01L3/00 ,  B01L9/06

Abstract: An analysis assembly is provided. The analysis assembly includes an analysis chip disposed on a supporting platform aligned in an x-y plane, wherein an active surface of the analysis chip is aligned along a z-axis opposite the supporting platform. A mounting assembly joined to the supporting platform is configured to hold the analysis chip in an analysis vessel, and wherein the z-axis is in alignment with a longitudinal axis of the analysis vessel.

公开(公告)号：US20190003892A1

公开(公告)日：2019-01-03

申请号：US15748611

申请日：2015-08-31

Applicant: Hewlett-Packard Development Company ,L.P.

Inventor： Francesco AIETA ,  Charles M. SANTORI ,  Anita ROGACS

IPC: G01J3/30 ,  G01J3/02 ,  G01J3/44 ,  G01N15/14 ,  G01N21/64 ,  G02B21/16

CPC classification number: G01J3/30 ,  G01J3/0208 ,  G01J3/0248 ,  G01J3/0256 ,  G01J3/2803 ,  G01J3/4406 ,  G01N15/1434 ,  G01N15/147 ,  G01N21/6458 ,  G01N21/658 ,  G01N2015/0053 ,  G01N2015/1006 ,  G01N2015/149 ,  G01N2021/6421 ,  G02B21/0008 ,  G02B21/0096 ,  G02B21/16

Abstract: In one implementation, a spectral microscope may comprise a substrate with a planar lens, the planar lens including a phase profile including an axial focus and an oblique focus, a light source to excite a signal of a particle among a plurality of particles, and a detector to receive light generated from the light source from the axial focus of the planar lens and a spectral color component of the excited signal of the particle from the oblique focus of the planar lens.