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公开(公告)号:US20210264687A1
公开(公告)日:2021-08-26
申请号:US17256353
申请日:2018-10-03
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Yang Lei , Viktor Shkolnikov , Daixi Xin
Abstract: An example method includes capturing a plurality of images of a rotating object using an imaging device optically coupled to a microscope. The method removing a first portion of a model of the rotating object based on a first contour of the rotating object in a first image of the plurality of images. The method includes orienting the model based on an amount of rotation of the rotating object between capture of the first image and capture of a second image of the plurality of images. The method also includes removing a second portion of the model of the rotating object based on a second contour of the rotating object in the second image.
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公开(公告)号:US20210033842A1
公开(公告)日:2021-02-04
申请号:US16606239
申请日:2018-04-27
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Viktor Shkolnikov , Daixi Xin , Yang Lei
IPC: G02B21/36 , G06T17/00 , H04N5/232 , G01N33/483
Abstract: A three-dimensional object modeling method may include applying a nonrotating nonuniform electric field to apply a dielectrophoretic torque to a three-dimensional object to rotate the three-dimensional object, capturing images of the object at different angles during rotation of the object and forming a three-dimensional model of the object based on the captured images.
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公开(公告)号:US12204085B2
公开(公告)日:2025-01-21
申请号:US16606239
申请日:2018-04-27
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Viktor Shkolnikov , Daixi Xin , Yang Lei
IPC: G02B21/36 , G01N33/483 , G06T17/00 , H04N23/66
Abstract: A three-dimensional object modeling method may include applying a nonrotating nonuniform electric field to apply a dielectrophoretic torque to a three-dimensional object to rotate the three-dimensional object, capturing images of the object at different angles during rotation of the object and forming a three-dimensional model of the object based on the captured images.
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公开(公告)号:US20240411121A1
公开(公告)日:2024-12-12
申请号:US18273967
申请日:2021-01-25
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Yang Lei , Fausto D'APUZZO
IPC: G02B21/26 , G05B19/4155
Abstract: A single point sensing system may include a microscope having a field of view, a single-point sensor having a focal point, a stage to support a substance, an actuator to move at least one of the single-point sensor and the stage relative to one another, and in alignment controller. The alignment controller is to identify a location of the substance on the stage based upon signals from the microscope and output sensor alignment signals to the actuator to align the location of the substance on the stage with the focal point of the single-point sensor based upon the identified location of the substance.
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公开(公告)号:US11486814B2
公开(公告)日:2022-11-01
申请号:US17255761
申请日:2018-10-01
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Fausto D'Apuzzo , Viktor Shkolnikov , Yang Lei
Abstract: A system and a method for sorting particles are provided. An example of a particle sorting system includes an array that includes a number of microfluidic ejectors. An optical sensor is focused on the array. A controller is used to identify a target particle proximate to a microfluidic ejector, and activate the microfluidic ejector to eject the target particle into a collection vessel.
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公开(公告)号:US11481964B2
公开(公告)日:2022-10-25
申请号:US16605949
申请日:2018-04-27
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Yang Lei , Viktor Shkolnikov , Daixi Xin
Abstract: A three-dimensional volume modeling method may include rotating a three-dimensional biological object having a translucent outer surface to different angular positions, capturing different two-dimensional images of the three-dimensional biological object, each of the different two-dimensional images being at a different angular position, and modeling an exterior of the three-dimensional biological object based upon the different two-dimensional images. The method may further involve identifying a point of an internal structure of the three-dimensional biological object each of the two-dimensional images and modeling the internal structure of the three-dimensional biological object in three-dimensional space relative to the exterior of the three-dimensional biological object by triangulating the point amongst the different two-dimensional images using a three-dimensional volumetric template of the three-dimensional biological object.
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公开(公告)号:US20210403849A1
公开(公告)日:2021-12-30
申请号:US16606742
申请日:2018-04-27
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Viktor Shkolnikov , Daixi Xin , Yang Lei
Abstract: A cellular object imaging system may include a growth platform. The growth platform may include a body having a cellular fluid suspension region, a media supply passage extending within the body to the cellular object fluid suspension region, at least one fluid pump on the body to selectively deliver media to the cellular object fluid suspension region, a waste discharge passage extending within the body from the cellular object fluid suspension region and a cellular object rotator on the body adjacent the cellular object fluid suspension region to rotate a cellular object within the cellular object fluid suspension region. The cellular object fluid suspension region permits optical imaging of the cellular object suspended in a fluid during rotation by the cellular object rotator.
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公开(公告)号:US20240355423A1
公开(公告)日:2024-10-24
申请号:US18684138
申请日:2021-08-25
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Yiming Zuo , Anton Wiranata , Amy Devitt , Yang Lei , Steven James Barcelo , Brian John Keefe
IPC: G16B40/10 , C12Q1/6844 , G01N21/64 , G16B40/20
CPC classification number: G16B40/10 , C12Q1/6844 , G01N21/6408 , G16B40/20 , G01N2201/1296
Abstract: Examples of methods are described herein. In some examples, a method includes determining signal variation data of a fluorescence signal measured from an amplification procedure of a nucleic acid sample. In some examples, the method includes detecting, using a machine learning model, a target nucleic acid strand in the nucleic acid sample based on the signal variation data.
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公开(公告)号:US20240201130A1
公开(公告)日:2024-06-20
申请号:US18590723
申请日:2024-02-28
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Viktor Shkolnikov , Yang Lei , Daixi Xin
IPC: G01N27/447 , B03C5/00 , B03C5/02
CPC classification number: G01N27/44713 , B03C5/005 , B03C5/026 , B03C2201/26
Abstract: In example implementations, an apparatus is provided. The apparatus includes a dielectrophoresis (DEP) separator, an electrical field generator, a tracking system, and a controller. The DEP separator is to separate a plurality of different particles. The electrical field generator is coupled to the DEP separator to apply a frequency to the DEP separator. The tracking system is to track a movement of a type of particles in the DEP separator. The controller is in communication with the electrical field generator to control the frequency and the tracking system to track the separation. The controller is to calculate a cross-over frequency from a cross-over frequency distribution for the type of particles based on a frequency sweep performed on the type of particles and the movement of the type of particles that is tracked.
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公开(公告)号:US11946902B2
公开(公告)日:2024-04-02
申请号:US17056488
申请日:2018-10-11
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Viktor Shkolnikov , Yang Lei , Daixi Xin
IPC: G01N27/447 , B03C5/00 , B03C5/02
CPC classification number: G01N27/44713 , B03C5/005 , B03C5/026 , B03C2201/26
Abstract: In example implementations, an apparatus is provided. The apparatus includes a dielectrophoresis (DEP) separator, an electrical field generator, a tracking system, and a controller. The DEP separator is to separate a plurality of different particles. The electrical field generator is coupled to the DEP separator to apply a frequency to the DEP separator. The tracking system is to track a movement of a type of particles in the DEP separator. The controller is in communication with the electrical field generator to control the frequency and the tracking system to track the separation. The controller is to calculate a cross-over frequency from a cross-over frequency distribution for the type of particles based on a frequency sweep performed on the type of particles and the movement of the type of particles that is tracked.
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