公开(公告)号：US07087896B2

公开(公告)日：2006-08-08

申请号：US11023234

申请日：2004-12-27

Applicant: Christopher H. Becker ,  Curtis A. Hastings ,  Scott M. Norton ,  Sushmita Mimi Roy ,  Weixun Wang ,  Haihong Zhou ,  Thomas Andrew Shaler ,  Praveen Kumar ,  Markus Anderle ,  Hua Lin

Inventor： Christopher H. Becker ,  Curtis A. Hastings ,  Scott M. Norton ,  Sushmita Mimi Roy ,  Weixun Wang ,  Haihong Zhou ,  Thomas Andrew Shaler ,  Praveen Kumar ,  Markus Anderle ,  Hua Lin

IPC: B01D59/44 ,  H01J49/00

CPC classification number: H01J49/0036

Abstract: Relative quantitative information about components of chemical or biological samples can be obtained from mass spectra by normalizing the spectra to yield peak intensity values that accurately reflect concentrations of the responsible species. A normalization factor is computed from peak intensities of those inherent components whose concentration remains constant across a series of samples. Relative concentrations of a component occurring in different samples can be estimated from the normalized peak intensities. Unlike conventional methods, internal standards or additional reagents are not required. The methods are particularly useful for differential phenotyping in proteomics and metabolomics research, in which molecules varying in concentration across samples are identified. These identified species may serve as biological markers for disease or response to therapy.

Abstract translation: 通过对光谱进行归一化，可以从质谱中获得关于化学或生物样品成分的相对定量信息，以产生准确反映负责物种浓度的峰值强度值。 归一化因子是由浓度在一系列样品中保持不变的那些固有成分的峰值强度计算出来的。 发生在不同样品中的组分的相对浓度可以从标准化峰强度估计。 与传统方法不同，不需要内标或附加试剂。 该方法对于蛋白质组学和代谢组学研究中的差异表型特别有用，其中鉴定了样品浓度变化的分子。 这些鉴定的物种可以作为疾病或治疗反应的生物标志物。

公开(公告)号：US20050172204A1

公开(公告)日：2005-08-04

申请号：US11038267

申请日：2005-01-21

Applicant: Hua Lin

Inventor： Hua Lin

IPC: H03M13/13 ,  H03M13/29 ,  H03M13/39 ,  H03M13/41 ,  H03M13/45 ,  H03M13/00 ,  H03M13/03

CPC classification number: H03M13/3972 ,  H03M13/2957 ,  H03M13/3723 ,  H03M13/3905

Abstract: A turbo decoding method is provided which is capable of realizing high-speed and highly accurate decoding operations by improving initialization of path metric values for parallel decoding processing. Turbo encoded code data is divided into a first to an N-th sub-code blocks and parallel decoding processing on these sub-code blocks is performed. “A priori initialization processing unit”s are provided which employ an initial value for calculation of a path metric value of each sub-code block excluding the first sub-code block in a forward direction as a final calculated value in a preceding sub-code block and an initial value for calculation of a path metric value of each sub-code block excluding the N-th sub-code block in a backward direction as a final calculated value in a following sub-code block. After the a priori initialization processing of path metric values, parallel decoding processing on each sub-code block is performed.

Abstract translation: 提供一种turbo解码方法，其能够通过改进用于并行解码处理的路径度量值的初始化来实现高速和高精度的解码操作。 Turbo编码代码数据被划分为第一到第N子代码块，并且对这些子代码块进行并行解码处理。 “提供了一种先验初始化处理单元，其采用用于计算除正向前的第一子代码块之外的每个子代码块的路径度量值的初始值作为前一子代码中的最终计算值 块和用于计算除了后向方向上的第N个子代码块的每个子代码块的路径度量值的初始值作为后续子代码块中的最终计算值。 在路径度量值的先验初始化处理之后，执行对每个子代码块的并行解码处理。

公开(公告)号：US20050024901A1

公开(公告)日：2005-02-03

申请号：US10901573

申请日：2004-07-27

Applicant: Jianping Ying ,  Hua Lin ,  Qiuhua Zhu ,  Wen-Yin Tsai

Inventor： Jianping Ying ,  Hua Lin ,  Qiuhua Zhu ,  Wen-Yin Tsai

IPC: H02M3/335 ,  H02M7/519

CPC classification number: H02M3/33569 ,  H02M3/33592 ,  H02M2001/0048 ,  Y02B70/1475 ,  Y02B70/1491 ,  Y10T307/625

Abstract: The push-pull converter for zero-voltage switching of the switches on the primary side of the transformer to have a relatively lower loss is proposed. Which includes: a transformer having a primary winding with a center tap and a secondary winding, an electrical energy storage device having a first terminal coupled to the center tap of the primary winding and a second terminal coupled to a ground, a first switch having a first terminal coupled to a first terminal of the primary winding and a second terminal coupled to the ground, a second switch having a first terminal coupled to the ground and a second terminal coupled to a second terminal of the primary winding, and a rectifier circuit coupled to the secondary winding for transforming an AC output of the secondary winding to a DC output.

Abstract translation: 提出了用于变压器初级侧的开关零电压开关的推挽转换器具有相对较低的损耗。 其包括：具有具有中心抽头和次级绕组的初级绕组的变压器，具有耦合到所述初级绕组的中心抽头的第一端子和耦合到地的第二端子的电能存储装置，具有第一开关的第一开关， 第一端子，其耦合到初级绕组的第一端子和耦合到地的第二端子，第二开关，其具有耦合到地的第一端子和耦合到初级绕组的第二端子的第二端子，以及整流器电路耦合 到次级绕组，用于将次级绕组的AC输出转换成DC输出。

公开(公告)号：US08781032B2

公开(公告)日：2014-07-15

申请号：US13319249

申请日：2010-04-08

Applicant: Hua Lin

Inventor： Hua Lin

IPC: H04L27/06 ,  H04L27/08

CPC classification number: H04B1/406 ,  H04B1/7115 ,  H04W52/0274 ,  Y02D70/1244 ,  Y02D70/40

Abstract: A communication apparatus includes two or more receiving units differing in characteristics. The apparatus further includes a data detecting unit detecting data to be received, in an input signal, and a selecting unit that selects one out of the two or more receiving units, depending upon detected result and characteristics of receiving units. In case data to be received is not contained in the input signal, the selecting unit selects a receiving unit whose power consumption during a period of time of not receiving the data is smaller than that of the other receiving unit(s) during a period of time of not receiving the data. In case the data to be received is contained in the input signal, the selecting unit selects a receiving unit from which a most satisfactory receiving quality is expected depending upon propagation environments of the input signal.

Abstract translation: 通信装置包括两个或更多个特性不同的接收单元。 该装置还包括数据检测单元，其根据检测到的接收单元的结果和特性，在输入信号中检测要接收的数据和选择单元，其选择两个或更多个接收单元中的一个。 在接收到的数据不包含在输入信号中的情况下，选择单元选择在不接收数据的时间段内的功率消耗小于其它接收单元的功率消耗的接收单元， 没有收到数据的时间。 在要接收的数据被包含在输入信号中的情况下，选择单元根据输入信号的传播环境选择期望最令人满意的接收质量的接收单元。

公开(公告)号：US20100235722A1

公开(公告)日：2010-09-16

申请号：US11997526

申请日：2006-07-31

Applicant: Hua Lin

Inventor： Hua Lin

IPC: H03M13/23 ,  G06F11/10 ,  H03M13/27

CPC classification number: H04L1/005 ,  H04B2201/70707 ,  H04L1/0068 ,  H04L1/08 ,  H04L1/1819 ,  H04L1/1845

Abstract: The second rate de-matching unit carries out a second rate de-matching step in parallel to each of two data defining the received data Rx for removing bits having been repeated in a second rate matching step having been carried out in a base station, or de-removing bits having been punctured in the second rate matching step having been carried out in a base station. The adders carry out a combining step in parallel in which data stored in the IR buffer is added to associated data among the two data. The first rate de-matching/turbo-decoding unit carries out a first rate de-matching step in which bits having been punctured in a first rate matching step having been carried out in a base station are repeated to data having been output from the input buffers, and simultaneously, repeatedly carries out a turbo-decoding step to the data.

Abstract translation: 第二速率去匹配单元与定义接收数据Rx的两个数据中的每一个并行执行第二速率去匹配步骤，用于在基站中执行的第二速率匹配步骤中去除已被重复的比特，或 在基站中执行的第二速率匹配步骤中去除已经被穿孔的比特。 加法器并行地执行组合步骤，其中将存储在IR缓冲器中的数据添加到两个数据中的相关联的数据。 第一速率去匹配/ turbo解码单元执行第一速率去匹配步骤，其中已经在基站中执行的第一速率匹配步骤中已被穿孔的比特重复到从输入端输出的数据 缓冲器，并且同时重复地对数据进行turbo解码步骤。

公开(公告)号：US20100062471A1

公开(公告)日：2010-03-11

申请号：US12088228

申请日：2006-09-29

Applicant: Aaron B. Kantor ,  Susan Goelz ,  Jun Deng ,  Hua Lin ,  Christopher Becker

Inventor： Aaron B. Kantor ,  Susan Goelz ,  Jun Deng ,  Hua Lin ,  Christopher Becker

IPC: C12Q1/02

CPC classification number: G01N33/5091 ,  G01N33/5008 ,  G01N33/5023 ,  G01N33/5047 ,  G01N33/564 ,  G01N2500/00 ,  G01N2500/10 ,  G01N2800/285 ,  G01N2800/52

Abstract: Biomarkers useful for identifying treatments for and monitoring treatment of patients with multiple sclerosis (MS) are provided, as well as methods for their identification, methods of diagnosing MS, relapse of MS patients and disease progression in MS patients.

Abstract translation: 提供了用于识别多发性硬化症（MS）患者治疗和监测治疗的生物标志物，以及其鉴定方法，MS诊断方法，MS患者复发和MS患者疾病进展。

公开(公告)号：US07543213B2

公开(公告)日：2009-06-02

申请号：US10850659

申请日：2004-05-21

Applicant: Hua Lin

Inventor： Hua Lin

IPC: H03M13/00

CPC classification number: H03M13/2975

Abstract: To provide a turbo decoding method capable of significantly improving efficiency of a determination as to whether or not to end decoding.If the decoding by a turbo decoder is started, a soft decision value of an element decoder is derived, and an ECR of a current frame is estimated from the soft decision value by an ECR criterion deriving portion. If determined to be an end as a result of an end determination of the decoding by the turbo decoder from a result of comparison with a last ECR value and the maximum number of times of repetition of decoding, a hard decision result and a decoding result are outputted, and if not determined to be the end, the number of times of repetition is counted up so as to repeat the above process.

Abstract translation: 提供能够显着提高关于是否结束解码的判定效率的turbo解码方法。 如果turbo解码器的解码开始，则导出元素解码器的软判决值，并且通过ECR准则导出部分从软判决值估计当前帧的ECR。 作为由turbo解码器从与最后的ECR值的比较结果和解码的重复次数的最大次数进行的解码结束确定结果的结果，硬判定结果和解码结果为 输出，如果不确定为结束，则重复的次数被计数，以重复上述处理。

公开(公告)号：US07049712B2

公开(公告)日：2006-05-23

申请号：US10901573

申请日：2004-07-29

Applicant: Jianping Ying ,  Hua Lin ,  Qiuhua Zhu ,  Wen-Yin Tsai

Inventor： Jianping Ying ,  Hua Lin ,  Qiuhua Zhu ,  Wen-Yin Tsai

IPC: H02J7/00

CPC classification number: H02M3/33569 ,  H02M3/33592 ,  H02M2001/0048 ,  Y02B70/1475 ,  Y02B70/1491 ,  Y10T307/625

Abstract: The push-pull converter for zero-voltage switching of the switches on the primary side of the transformer to have a relatively lower loss is proposed. Which includes: a transformer having a primary winding with a center tap and a secondary winding, an electrical energy storage device having a first terminal coupled to the center tap of the primary winding and a second terminal coupled to a ground, a first switch having a first terminal coupled to a first terminal of the primary winding and a second terminal coupled to the ground, a second switch having a first terminal coupled to the ground and a second terminal coupled to a second terminal of the primary winding, and a rectifier circuit coupled to the secondary winding for transforming an AC output of the secondary winding to a DC output.

Abstract translation: 提出了用于变压器初级侧的开关零电压开关的推挽转换器具有相对较低的损耗。 其包括：具有具有中心抽头和次级绕组的初级绕组的变压器，具有耦合到所述初级绕组的中心抽头的第一端子和耦合到地的第二端子的电能存储装置，具有第一开关的第一开关， 第一端子，其耦合到初级绕组的第一端子和耦合到地的第二端子，第二开关，其具有耦合到地的第一端子和耦合到初级绕组的第二端子的第二端子，以及整流器电路耦合 到次级绕组，用于将次级绕组的AC输出转换成DC输出。

公开(公告)号：US06265716B1

公开(公告)日：2001-07-24

申请号：US09515357

申请日：2000-02-29

Applicant: Joanna M. Hunter ,  Hua Lin ,  Christopher H. Becker

Inventor： Joanna M. Hunter ,  Hua Lin ,  Christopher H. Becker

IPC: H01J4404

CPC classification number: H01J49/164 ,  G01N1/22 ,  H01J49/0468

Abstract: A sample preparation method is disclosed for volatilization and mass spectrometric analysis of nonvolatile high molecular weight molecules. Photoabsorbing molecules having significant sublimation rates at room temperature under vacuum, and preferably containing hydroxy functionalities, are disclosed for use as matrices in matrix-assisted laser desorption/ionization mass spectrometry. The samples are typically cooled in the mass spectrometer to temperatures significantly below room temperature.

Abstract translation: 公开了用于非挥发性高分子量分子的挥发和质谱分析的样品制备方法。 公开了在真空下，优选含有羟基官能团的具有显着升华速率的光吸收分子，用作基质辅助激光解吸/电离质谱法中的基质。 样品通常在质谱仪中冷却至明显低于室温的温度。

公开(公告)号：US6104028A

公开(公告)日：2000-08-15

申请号：US86993

申请日：1998-05-29

Applicant: Joanna M. Hunter ,  Hua Lin ,  Christopher H. Becker

Inventor： Joanna M. Hunter ,  Hua Lin ,  Christopher H. Becker

IPC: G01N1/00 ,  H01J49/04 ,  H01J49/16 ,  H01J44/04

CPC classification number: H01J49/164 ,  H01J49/0468 ,  G01N1/22

Abstract: A sample preparation method is disclosed for volatilization and mass spectrometric analysis of nonvolatile high molecular weight molecules. Photoabsorbing molecules having significant sublimation rates at room temperature under vacuum, and preferably containing hydroxy functionalities, are disclosed for use as matrices in matrix-assisted laser desorption/ionization mass spectrometry. The samples are typically cooled in the mass spectrometer to temperatures significantly below room temperature.

Abstract translation: 公开了用于非挥发性高分子量分子的挥发和质谱分析的样品制备方法。 公开了在真空下，优选含有羟基官能团的具有显着升华速率的光吸收分子，用作基质辅助激光解吸/电离质谱法中的基质。 样品通常在质谱仪中冷却至明显低于室温的温度。