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57 条记录 (耗时 0.034 秒)

    Automatic necleic acid purification apparatus and method for aerosol-protecting
    11.
    发明授权
    Automatic necleic acid purification apparatus and method for aerosol-protecting 有权
    自动碳酸净化装置及气溶胶保护方法

    公开(公告)号：US09273306B2

    公开(公告)日：2016-03-01

    申请号：US13885556

    申请日：2011-11-18

    申请人： Han Oh Park ,  Byung Rae Jeong ,  Kwon Sic Kim

    发明人： Han Oh Park ,  Byung Rae Jeong ,  Kwon Sic Kim

    IPC分类号： C12Q1/68 ,  B01L3/00 ,  C12N15/10

    CPC分类号： C12N15/1013 ,  C12Q1/68

    摘要： Disclosed is an automatic nucleic acid purification apparatus which can prevent pollution due to aerosol generated from a biological sample containing high concentration target nucleic acid when the biological sample containing the high concentration target nucleic acid is mixed with other biological sample containing low concentration target nucleic acid or not containing the target nucleic acid. Further, disclosed is an automatic nucleic acid purification apparatus which can be applied to all kinds of nucleic acid purification equipments for purifying a plurality of biological samples using a magnet rode or a multi-pipette block moving in two or three axial directions, and which can minimize pollution due to the aerosol generated from the biological sample containing high concentration target nucleic acid and also can obtain accurate results.

    摘要翻译： 公开了一种自动核酸纯化装置，当含有高浓度靶核酸的生物样品与含有低浓度靶核酸的其他生物样品混合时，可以防止由含有高浓度靶核酸的生物样品产生的气溶胶引起的污染，或 不含靶核酸。 此外，公开了一种自动核酸纯化装置，其可以应用于使用磁珠或多个移液管块在两个或三个轴向移动的多个生物样品的各种核酸纯化设备，并且其可以 尽可能减少由含有高浓度靶核酸的生物样品产生的气溶胶引起的污染，并可获得准确的结果。

    METHOD OF IDENTIFYING NUCLEIC ACID-CONTAINING OBJECT
    14.
    发明申请
    METHOD OF IDENTIFYING NUCLEIC ACID-CONTAINING OBJECT 审中-公开
    识别含有核酸的物体的方法

    公开(公告)号：US20140087377A1

    公开(公告)日：2014-03-27

    申请号：US14005213

    申请日：2012-03-13

    申请人： Han Oh Park ,  Jung Young Choi ,  Eun Su Han ,  Gu Young Song ,  Won Seok Jang

    发明人： Han Oh Park ,  Jung Young Choi ,  Eun Su Han ,  Gu Young Song ,  Won Seok Jang

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/6816 ,  C12Q1/6818 ,  C12Q2521/327 ,  C12Q2525/121 ,  C12Q2563/185

    摘要： The present invention relates to a method of identifying nucleic acid-containing object, more precisely a method of identifying nucleic acid-containing object which comprises the following steps: (1) preparing nucleic acid-containing object having the nucleotide sequence complementary to the nucleotide sequence of RNA-dual probe; (2) reacting the nucleic acid included in the object with the buffer containing the RNA-dual probe conjugated with a reporter and a quencher respectively and RNase; and (3) detecting fluorescence generated from the reporter. The method of identifying an object of the present invention provides labeling sensitivity 100 times as high as that of the conventional method using sequencing or labeling with fluorescent materials, takes advantages of shorter analysis time, facilitates different labeling on a variety of products according to fluorescent materials, and makes possible unlimited product administration by product group and batch in real production process by differentiating the nucleotide sequence of each oligonucleotide.

    摘要翻译： 本发明涉及鉴定含核酸物质的方法，更准确地说，一种鉴定含核酸物质的方法，包括以下步骤：（1）制备具有与核苷酸序列互补的核苷酸序列的含核酸物质 的RNA双探针; （2）将包含在物体中的核酸与分别与报告子和猝灭剂结合的RNA双重探针的缓冲液和RNase分别反应; 和（3）检测从报告物产生的荧光。 识别本发明的目的的方法提供了使用荧光材料进行测序或标记的常规方法的100倍的标签灵敏度，具有较短的分析时间的优点，便于根据荧光材料对各种产品进行不同的标记 并通过区分每个寡核苷酸的核苷酸序列，在实际生产过程中使产品组和批次无限制地进行产品管理。

    Real-time PCR monitoring apparatus
    18.
    发明授权
    Real-time PCR monitoring apparatus 有权
    实时PCR监测仪

    公开(公告)号：US08427643B2

    公开(公告)日：2013-04-23

    申请号：US12598061

    申请日：2008-06-17

    申请人： Hanee Park ,  Il kyu Choi ,  Han Oh Park

    发明人： Hanee Park ,  Il kyu Choi ,  Han Oh Park

    IPC分类号： G01J4/00

    CPC分类号： G01N21/6445 ,  G01J3/0224 ,  G01J3/4406 ,  G01N21/6452 ,  G01N2021/6478 ,  G01N2021/6484 ,  G01N2201/0631 ,  G01N2201/0636

    摘要： The present invention relates to a real-time PCR monitoring apparatus for real-time monitoring production of reaction product produced during the reaction while performing nucleic acid amplification such as PCR for various kinds of trace samples. Specifically, the present invention relates to an apparatus for real-time monitoring biochemical reaction for efficiently dividing interference between an excitation light and a fluorescence, which includes a polarizer, a polarizing beam splitter, a polarization converter and so on.

    摘要翻译： 本发明涉及一种用于实时监测在反应过程中产生的反应产物的实时PCR监测装置，同时对各种痕量样品进行核酸扩增如PCR。 具体地说，本发明涉及一种用于实时监测生化反应的装置，用于有效地分离激发光和荧光之间的干扰，其包括偏振器，偏振分束器，偏振转换器等。

    Miniaturized apparatus for real-time monitoring
    19.
    发明授权
    Miniaturized apparatus for real-time monitoring 有权
    用于实时监控的小型化设备

    公开(公告)号：US08329106B2

    公开(公告)日：2012-12-11

    申请号：US11661410

    申请日：2005-09-01

    申请人： Han Oh Park ,  Hanee Park ,  Jong Soo Baek

    发明人： Han Oh Park ,  Hanee Park ,  Jong Soo Baek

    IPC分类号： G01N21/64 ,  B01J19/00

    CPC分类号： G01N21/645 ,  B01L3/5025 ,  B01L7/525 ,  B01L2300/0838 ,  B01L2300/0841 ,  B01L2300/087

    摘要： The present invention relates to a apparatus for quantitative continuous real-time monitoring to monitor a continuous reaction of biochemical reagent and the reaction, such as DNA. More particularly, the present invention is directed to a miniaturized apparatus for real-time monitoring of biochemical reaction, which comprises capillary tubes (100) wherein biochemical reaction mixture flow; a thermal conduction block (120) which is coiled with capillary tube several rounds in order and composed of several blocks for temperature control of which temperatures are different from each other for heating or cooling the biochemical reaction mixture which flow in capillary tube, and a temperature controller which controls the temperature of above temperature control block; a radiation part (130) to radiate the reaction mixture flowing through the capillary tube and a light receiving section (140) which receives and measures the intensity of the fluorescence generated from the capillary tubes.

    摘要翻译： 本发明涉及用于定量连续实时监测的装置，用于监测生物化学试剂和反应如DNA的连续反应。 更具体地，本发明涉及一种用于实时监测生物化学反应的小型化装置，其包括其中生物化学反应混合物流动的毛细管（100） 热传导块（120），其顺序地由毛细管螺旋成几圈，并且由用于温度彼此不同的温度控制的几个块组成，用于加热或冷却在毛细管中流动的生物化学反应混合物，温度 控制器控制上述温度控制块的温度; 用于辐射流过毛细管的反应混合物的辐射部分（130）和接收并测量从毛细管产生的荧光强度的光接收部分（140）。

    LACTIC ACID BACTERIA ISOLATED FROM MOTHER'S MILK WITH PROBIOTIC ACTIVITY AND INHIBITORY ACTIVITY AGAINST BODY WEIGHT AUGMENTATION
    20.
    发明申请
    LACTIC ACID BACTERIA ISOLATED FROM MOTHER'S MILK WITH PROBIOTIC ACTIVITY AND INHIBITORY ACTIVITY AGAINST BODY WEIGHT AUGMENTATION 有权
    从母乳中分离的乳酸菌具有抗生素活性和抑制体重反应的活性

    公开(公告)号：US20100203025A1

    公开(公告)日：2010-08-12

    申请号：US12376368

    申请日：2007-05-14

    申请人： Ji Hee Kang ,  Byeung Il You ,  Sung Il Yun ,  Han Oh Park

    发明人： Ji Hee Kang ,  Byeung Il You ,  Sung Il Yun ,  Han Oh Park

    IPC分类号： A61K35/74 ,  C12N1/20 ,  A23L1/28 ,  A23K3/00 ,  C07K14/335 ,  C07H21/04 ,  C12N15/63 ,  A61P3/04

    CPC分类号： C12R1/225 ,  A23C9/1234 ,  A23L33/135 ,  A23L33/18 ,  A23Y2220/37 ,  A61K38/00 ,  C07K14/335 ,  C12N1/20

    摘要： The present invention relates to a lactic acid bacterium isolated from human mother's milk, more precisely a Lactobacillus gasseri BNR17 strain that is isolated from Korean mother's milk and has excellent probiotic activity including acid resistance, bile acid resistance and antimicrobial activity and weight gaining inhibitory effect as well Again, the Lactobacillus gasseri BNR17 of the present invention has excellent acid resistance, bile acid resistance, enteric absorption activity and antimicrobial activity against pathogenic microorganisms, in addition to the weight gaining inhibitory effect by synthesizing indigestible polysaccharides from monosaccharides included in food taken and releasing the synthesized polysaccharides out of the body. Therefore, the strain of the invention, owing to such beneficiary effects, can be effectively used not only for the production of fermented milk, other fermented food products and animal feeds but also for the production of live cell products and food additives for preventing weight gaining.

    摘要翻译： 本发明涉及从人母乳分离的乳酸菌，更准确地说是从韩国母乳中分离的加氏乳杆菌BNR17菌株，具有优异的益生菌活性，包括耐酸性，耐胆汁酸性和抗微生物活性和增重抑制作用 另外，本发明的加氏乳杆菌BNR17除了通过合成不可消化的多糖外，还包括在食物摄取和释放中包含的单糖，而且具有优异的抗酸性，耐胆汁酸性，肠吸收活性和抗病原微生物的抗微生物活性 合成的多糖出体外。 因此，由于这种受益效应，本发明的菌株不仅可以有效地用于生产发酵乳，其他发酵食品和动物饲料，而且可用于生产活细胞产品和食品添加剂，以防止体重增加 。