公开(公告)号：US20080084595A1

公开(公告)日：2008-04-10

申请号：US11907121

申请日：2007-10-09

申请人： Hideki Chouji ,  Shigeo Maeda ,  Hidetoshi Kotera ,  Isaku Kanno

发明人： Hideki Chouji ,  Shigeo Maeda ,  Hidetoshi Kotera ,  Isaku Kanno

IPC分类号： G02B26/08

CPC分类号： G11B7/13925 ,  G02B26/06 ,  G02B26/0825 ,  G11B7/1362

摘要： A variable shape mirror is composed of a substrate, a lower electrode film which is disposed on the substrate, a piezoelectric film which is disposed on the lower electrode film, an upper electrode film which is disposed on the piezoelectric film, an insulating film which is disposed on the upper electrode film, and a mirror film which is disposed on the insulating film. The lower electrode film, the piezoelectric film, and the upper electrode film function as a driving portion to deform the mirror film. The upper electrode film is divided into a plurality of divided electrodes and the driving portion includes a part which performs main deformation of the mirror film and a part which performs fine adjustment of deformation of the mirror film.

摘要翻译： 可变形状镜由基板，设置在基板上的下电极膜，设置在下电极膜上的压电膜，设置在压电膜上的上电极膜，绝缘膜， 设置在上电极膜上，镜面膜设置在绝缘膜上。 下电极膜，压电膜和上电极膜用作使镜面膜变形的驱动部。 上电极膜被分成多个分开的电极，并且驱动部分包括执行镜膜的主要变形的部分和执行镜膜的变形的微调的部分。

公开(公告)号：US20070222998A1

公开(公告)日：2007-09-27

申请号：US11724681

申请日：2007-03-15

申请人： Syo Sasaki ,  Tomohiro Matsushita ,  Takeo Nishikawa ,  Natsuko Horiguchi ,  Hidetoshi Kotera ,  Hiroo Iwata

发明人： Syo Sasaki ,  Tomohiro Matsushita ,  Takeo Nishikawa ,  Natsuko Horiguchi ,  Hidetoshi Kotera ,  Hiroo Iwata

IPC分类号： G01N21/55

CPC分类号： G01N21/553 ,  G06K9/0004

摘要： A surface plasmon sensor includes a light guide reflection plate, a surface plasmon resonance layer formed on a first surface of the light guide reflection plate, a light emitting unit having a light source disposed on an end surface of the light guide reflection plate, and a light receiving element. The surface plasmon resonance layer includes a metal layer. The light guide reflection plate includes at least one first reflection surface inclined against the first surface. The light guide reflection plate is configured to transmit light emitted by the light source. The at least one first reflection surface is configured reflect the light to the surface plasmon resonance layer. The metal layer is configured to reflect the light reflected by the at least one first reflection surface. The light receiving element is configured to receive the light reflected by the metal layer.

摘要翻译： 表面等离子体激元传感器包括导光反射板，形成在导光反射板的第一表面上的表面等离子体共振层，具有设置在导光反射板的端面上的光源的发光单元和 光接收元件。 表面等离子体共振层包括金属层。 光导反射板包括至少一个倾斜抵靠第一表面的第一反射表面。 导光反射板被配置为透射由光源发射的光。 所述至少一个第一反射表面被配置为将光反射到表面等离子体共振层。 金属层被配置为反射由至少一个第一反射表面反射的光。 光接收元件被配置为接收由金属层反射的光。

公开(公告)号：US5315233A

公开(公告)日：1994-05-24

申请号：US699513

申请日：1991-05-14

申请人： Kazuyuki Sakiyama ,  Akira Ahagon ,  Hidetoshi Kotera ,  Hiromi Kita

发明人： Kazuyuki Sakiyama ,  Akira Ahagon ,  Hidetoshi Kotera ,  Hiromi Kita

IPC分类号： G01R33/00 ,  G01R29/08 ,  G01R33/10 ,  G06F17/50 ,  G06J1/02 ,  G21K1/00 ,  G01R33/02 ,  H01J25/00

CPC分类号： G01R29/0892

摘要： In order to take into account the effect of load resistance applied to an electromagnetic field in analyzing an electromagnetic wave oscillator, the present invention arranges a resistance equivalent to the load resistance in the analytical region, and converts a voltage applied to the load and the current flowing therein into an electric field component and a magnetic field component to analyze the electromagnetic field distribution of the entire analytical region. The motion of an electrical charge is thus analyzed taking into account a force applied to the electric charge by the electromagnetic field distribution. This compound analysis of both the electric charge motion and the electromagnetic field is alternately and repeatedly performed.

摘要翻译： 为了考虑在分析电磁波振荡器时对电磁场施加的负载电阻的影响，本发明在分析区域中设置与负载电阻相当的电阻，并且将施加到负载的电压和电流 在其中流入电场分量和磁场分量以分析整个分析区域的电磁场分布。 因此，考虑到通过电磁场分布施加到电荷的力，分析电荷的运动。 这种电荷运动和电磁场的复合分析交替重复执行。

公开(公告)号：US07692795B2

公开(公告)日：2010-04-06

申请号：US11724681

申请日：2007-03-15

申请人： Syo Sasaki ,  Tomohiko Matsushita ,  Takeo Nishikawa ,  Natsuko Horiguchi ,  Hidetoshi Kotera ,  Hiroo Iwata

发明人： Syo Sasaki ,  Tomohiko Matsushita ,  Takeo Nishikawa ,  Natsuko Horiguchi ,  Hidetoshi Kotera ,  Hiroo Iwata

IPC分类号： G01N21/55

CPC分类号： G01N21/553 ,  G06K9/0004

摘要： A surface plasmon sensor includes a light guide reflection plate, a surface plasmon resonance layer formed on a first surface of the light guide reflection plate, a light emitting unit having a light source disposed on an end surface of the light guide reflection plate, and a light receiving element. The surface plasmon resonance layer includes a metal layer. The light guide reflection plate includes at least one first reflection surface inclined against the first surface. The light guide reflection plate is configured to transmit light emitted by the light source. The at least one first reflection surface is configured reflect the light to the surface plasmon resonance layer. The metal layer is configured to reflect the light reflected by the at least one first reflection surface. The light receiving element is configured to receive the light reflected by the metal layer.

摘要翻译： 表面等离子体激元传感器包括导光反射板，形成在导光反射板的第一表面上的表面等离子体共振层，具有设置在导光反射板的端面上的光源的发光单元和 光接收元件。 表面等离子体共振层包括金属层。 光导反射板包括至少一个倾斜抵靠第一表面的第一反射表面。 导光反射板被配置为透射由光源发射的光。 所述至少一个第一反射表面被配置为将光反射到表面等离子体共振层。 金属层被配置为反射由至少一个第一反射表面反射的光。 光接收元件被配置为接收由金属层反射的光。

公开(公告)号：US20070192075A1

公开(公告)日：2007-08-16

申请号：US10590016

申请日：2005-02-14

申请人： Tetsuya Matsuda ,  Akira Amano ,  Hidetoshi Kotera ,  Kenta Hori ,  Jianyin Lu ,  Nobuaki Sarai ,  Satoshi Matsuoka ,  Akinori Noma ,  Takao Shimayoshi

发明人： Tetsuya Matsuda ,  Akira Amano ,  Hidetoshi Kotera ,  Kenta Hori ,  Jianyin Lu ,  Nobuaki Sarai ,  Satoshi Matsuoka ,  Akinori Noma ,  Takao Shimayoshi

IPC分类号： G06G7/48 ,  G06G7/58

CPC分类号： G16H50/50

摘要： With conventional simulation devices, the assumption was that only cells would be simulated, and thus the simulation devices had the problem that simulations on the level of tissue, organs, or individual organisms, which are collections of cells, were not possible. The present invention is an organism simulation device that is provided with two or more different simulator parts that calculate the behavior of organism structural elements, a data output part that visually outputs simulation results, and a simulation controller that controls the transfer of data between the two or more different simulator parts and the data output part based on simulation scenario information, which is information on the flow of data and the operation sequence. With this organism simulation device, an environment in which simulation of an organism can be performed more comprehensively and with higher precision can be provided with ease.

摘要翻译： 使用传统的模拟装置，假设只有细胞被模拟，因此仿真装置的问题在于，不可能对作为细胞集合的组织，器官或个体生物体的水平进行模拟。 本发明是一种生物模拟装置，其具有计算生物体结构要素的行为的两个或多个不同的模拟器部分，可视地输出模拟结果的数据输出部分，以及控制两者之间的数据传送的模拟控制器 或更多不同的模拟器部分和数据输出部分，其基于模拟情景信息，其是关于数据流和操作序列的信息。 利用这种有机体模拟装置，可以容易地提供可以更全面地和更高精度地进行生物体的模拟的环境。

公开(公告)号：US20070091482A1

公开(公告)日：2007-04-26

申请号：US11585861

申请日：2006-10-25

申请人： Hideki Chouji ,  Shigeo Maeda ,  Hidetoshi Kotera ,  Isaku Kanno

发明人： Hideki Chouji ,  Shigeo Maeda ,  Hidetoshi Kotera ,  Isaku Kanno

IPC分类号： G02B5/08

CPC分类号： G11B7/13927 ,  G02B26/0825 ,  G11B7/1362

摘要： A variable-shape mirror has a substrate, a lower electrode film formed on the substrate, a piezoelectric film formed on the lower electrode film, an upper electrode film formed on the piezoelectric film, and a mirror film formed directly on the substrate and arranged to be surrounded by a driver portion constituted by the lower electrode film, the piezoelectric film, and the upper electrode film. The mirror film is arranged on a movable portion provided in the substrate, and at least part of the driver portion is arranged on the movable portion.

摘要翻译： 可变形反射镜具有基板，形成在基板上的下电极膜，形成在下电极膜上的压电膜，形成在压电膜上的上电极膜，以及直接形成在基板上的镜膜， 被由下电极膜，压电膜和上电极膜构成的驱动部分包围。 镜膜布置在设置在基板中的可移动部分上，并且驱动器部分的至少一部分布置在可动部分上。

公开(公告)号：US08876361B2

公开(公告)日：2014-11-04

申请号：US12934030

申请日：2009-03-27

申请人： Hidetoshi Kotera ,  Takaaki Suzuki ,  Kensuke Kanda ,  Yuichiro Noda

发明人： Hidetoshi Kotera ,  Takaaki Suzuki ,  Kensuke Kanda ,  Yuichiro Noda

IPC分类号： B01F11/00 ,  B01F11/02 ,  G01N33/49

CPC分类号： B01F11/0266 ,  G01N33/49

摘要： A fluid agitation method is provided, whereby a swirling flow is generated in a trace amount of fluid, thereby agitating the fluid. The fluid agitation method includes introducing the fluid into an agitation chamber (3) including a wall having an uneven mass distribution, and applying oscillation (F) to the wall with frequencies varying in a predetermined frequency range. The uneven mass distribution of the wall is attained, for example, by arranging a plurality of thickened portions (11 to 18) of different thicknesses in a ring.

摘要翻译： 提供流体搅拌方法，由此在微量流体中产生旋流，从而搅动流体。 流体搅拌方法包括将流体引入包括具有不均匀质量分布的壁的搅拌室（3）中，并且在预定频率范围内变化的频率向壁施加振荡（F）。 壁的质量分布不均匀，例如通过在环中布置不同厚度的多个增厚部（11〜18）来实现。

公开(公告)号：US20090107909A1

公开(公告)日：2009-04-30

申请号：US12227400

申请日：2007-05-22

申请人： Hidetoshi Kotera ,  Masao Washizu ,  Hidehiro Oana

发明人： Hidetoshi Kotera ,  Masao Washizu ,  Hidehiro Oana

IPC分类号： B01D17/025

CPC分类号： G01N33/491 ,  B01L3/502753 ,  B01L3/502761 ,  B01L2200/0652 ,  B01L2200/0668 ,  B01L2300/0809 ,  B01L2300/0864 ,  B01L2400/0457 ,  B01L2400/086 ,  Y10T137/2082 ,  Y10T137/212 ,  Y10T137/218

摘要： It is intended to provide a microchannel for separating blood plasma whereby blood plasma can be conveniently separated on a microchip.A microchannel comprising: a substrate body (10a); a separation channel (11) which is formed within the substrate body (10a) and extended in the direction parallel to the longitudinal direction of the substrate body (10a); at least two (first and second) connection ports (13a, 14a) which are formed at one end of the separation channel (11) close to the thickness direction perpendicular to the longitudinal direction of the substrate body (10a); and first and second branch channels (13, 14) which are formed within the substrate body (10a) and connected respectively to the first and second connection ports (13a, 14a). In the state where the substrate body (10a) is extended perpendicular to the direction of gravitational force, a blood sample containing blood cells and plasma is flown from one end (11a) side of the separation channel (11). Before the blood sample attains the other end (11b) of the separation channel (11), the blood cells in the blood sample settle out. The blood cells having settled out are then introduced into the branch channel (14) that is located lower in the direction of gravitational force between the first and second branch channels. On the other hand, the major portion of the blood plasma is introduced into the other branch channel (13) located upper in the direction of gravitational force.

摘要翻译： 旨在提供用于分离血浆的微通道，从而可以在微芯片上方便地分离血浆。 一种微通道，包括：衬底主体（10a）; 分离通道（11），其形成在所述基板主体（10a）内并沿与所述基板主体（10a）的纵向方向平行的方向延伸; 至少两个（第一和第二）连接端口（13a，14a），其形成在与所述基板主体（10a）的纵向方向垂直的厚度方向上的分离通道（11）的一端处; 以及第一和第二分支通道（13,14），其形成在所述基板主体（10a）内并分别连接到所述第一和第二连接端口（13a，14a）。 在基板主体（10a）垂直于重力方向延伸的状态下，含有血细胞和血浆的血液样本从分离通道（11）的一端（11a）侧流出。 在血液样本达到分离通道（11）的另一端（11b）之前，血液样品中的血细胞沉降。 然后将沉淀出的血细胞引入位于第一和第二分支通道之间的重力方向下方较低的分支通道（14）中。 另一方面，等离子体的主要部分被引入位于重力方向上方的另一个分支通道（13）中。

公开(公告)号：US08871433B2

公开(公告)日：2014-10-28

申请号：US13501897

申请日：2010-10-14

申请人： Takaaki Suzuki ,  Hidetoshi Kotera ,  Isaku Kanno ,  Daisuke Hiramaru

发明人： Takaaki Suzuki ,  Hidetoshi Kotera ,  Isaku Kanno ,  Daisuke Hiramaru

IPC分类号： G03F7/20 ,  G03F7/00 ,  B81C1/00 ,  B81C99/00 ,  G03F1/00 ,  G03F1/38

CPC分类号： G03F7/0037 ,  B81C1/00126 ,  B81C99/002 ,  G03F1/14 ,  G03F1/38 ,  G03F1/50 ,  G03F7/2002 ,  G03F7/201

摘要： The disclosed method for producing a microstructure can form a complicated three-dimensionally formed microstructure with few steps.A first mask pattern (22) containing a light transmitting section and a light blocking section is disposed along an unexposed photosensitive resin (42), and a second mask pattern (32) containing a light transmitting section and a light blocking section is disposed on the reverse side of the first mask pattern (22) from the photosensitive resin (42). Additionally, by means of integrally rotating the photosensitive resin (42) and the first mask pattern (22) around a central axis (Z) that passes through the photosensitive resin (42) and the first mask pattern (22), and at the same time radiating exposure light from the reverse side of the second mask pattern (32) from the photosensitive resin (42) and the first mask pattern (22) in a direction that is inclined obliquely with respect to the direction of the central axis (Z), the light beam of the exposure light that is transmitted through the light transmitting section of the second mask pattern (32) and the light transmitting section of the first mask pattern (22) exposes the photosensitive resin (42).

摘要翻译： 所公开的微结构制造方法可以以几步形成复杂的三维形成的微结构。 沿着未曝光的感光性树脂（42）设置包含透光部和遮光部的第一掩模图案（22），将含有透光部和遮光部的第二掩模图案（32）配置在 第一掩模图案（22）与感光性树脂（42）的反面。 此外，通过使感光性树脂（42）和第一掩模图案（22）围绕通过感光性树脂（42）和第一掩模图案（22）的中心轴（Z）一体地旋转，并且在同一 在相对于中心轴线（Z）的方向倾斜倾斜的方向上，从第二掩模图案的背面照射来自感光性树脂（42）和第一掩模图案（22）的曝光光， 通过第二掩模图案（32）的透光部分透射的曝光光的光束和第一掩模图案（22）的透光部分暴露感光性树脂（42）。

公开(公告)号：US20140099243A1

公开(公告)日：2014-04-10

申请号：US14119724

申请日：2012-05-16

申请人： Hidetoshi Kotera ,  Atsuhito Okonogi ,  Masataka Ohoka ,  Katsuya Maruo

发明人： Hidetoshi Kotera ,  Atsuhito Okonogi ,  Masataka Ohoka ,  Katsuya Maruo

IPC分类号： G03F7/004 ,  B01L3/00

CPC分类号： G03F7/0045 ,  B01J2219/00637 ,  B01J2219/00743 ,  B01L3/508 ,  C08G59/24 ,  C08G59/3218 ,  C08L63/00 ,  C08L2205/02 ,  G03F7/038

摘要： It is intended to obtain a photosensitive resin composition that is capable of forming a highly fine pattern with a high aspect ratio while attaining the high adhesion of the pattern to a substrate, having low autofluorescence, and being exceedingly suitable for producing a biochip that causes exceedingly low damage on cultured cells. The photosensitive resin composition for forming a biochip of the present invention contains: an epoxy compound (A1) of a particular structure having an oxycyclohexane skeleton having an epoxy group; an epoxy compound (A2) of a particular structure which is a polyvalent carboxylic acid derivative having an epoxidized cyclohexenyl group; a cationic photoinitiator (B); and a solvent (C).

摘要翻译： 旨在获得能够形成具有高纵横比的高精细图案的感光性树脂组合物，同时获得图案对基材的高粘附性，具有低自发荧光，并且非常适合于生产极其重要的生物芯片 培养细胞损伤小。 本发明的生物芯片形成用感光性树脂组合物含有具有环氧基的氧基环己烷骨架的具体结构的环氧化合物（A1） 具有环氧化环己烯基的多价羧酸衍生物的具体结构的环氧化合物（A2） 阳离子光引发剂（B）; 和溶剂（C）。