公开(公告)号：US07695493B2

公开(公告)日：2010-04-13

申请号：US10865736

申请日：2004-06-09

申请人： Vahid Saadat ,  Richard C. Ewers ,  Tracy D. Maahs ,  Alexander Khairkhahan ,  Kenneth J. Michlitsch

发明人： Vahid Saadat ,  Richard C. Ewers ,  Tracy D. Maahs ,  Alexander Khairkhahan ,  Kenneth J. Michlitsch

IPC分类号： A61B17/08 ,  A61D1/00

CPC分类号： A61B17/0401 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/0644 ,  A61B2017/00867 ,  A61B2017/0454 ,  A61B2017/0464 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2090/037

摘要： Systems for optimizing anchoring force are described herein. In securing tissue folds, over-compression of the tissue directly underlying the anchors is avoided by utilizing tissue anchors having expandable arms configured to minimize contact area between the anchor and tissue. When the anchor is in its expanded configuration, a load is applied to the anchor until it is optimally configured to accommodate a range of deflections while the anchor itself exerts a substantially constant force against the tissue. Various devices, e.g., stops, spring members, fuses, strain gauges, etc., can be used to indicate when the anchor has been deflected to a predetermined level within the optimal range. Moreover, other factors to affect the anchor characteristics include, e.g., varying the number of arms or struts of the anchor, positioning of the arms, configuration of the arms, the length of the collars, etc.

摘要翻译： 这里描述了用于优化锚固力的系统。 在固定组织褶皱时，通过利用具有可扩张臂的组织锚来避免直接位于锚固件正下方的组织的过度压缩，所述组织锚构造成使锚和组织之间的接触面积最小化。 当锚固件处于其膨胀构型时，将负载施加到锚固件，直到其被最佳地构造成适应一定范围的偏转，同时锚固件本身对组织施加基本恒定的力。 可以使用各种装置，例如止动件，弹簧构件，保险丝，应变计等来指示锚固件何时被偏转到最佳范围内的预定水平。 此外，影响锚固特征的其他因素包括例如改变锚的臂或支柱的数量，臂的定位，臂的构型，套环的长度等。

公开(公告)号：US20100042115A1

公开(公告)日：2010-02-18

申请号：US12579295

申请日：2009-10-14

申请人： Vahid Saadat ,  Chris Rothe ,  Richard C. Ewers

发明人： Vahid Saadat ,  Chris Rothe ,  Richard C. Ewers

IPC分类号： A61B17/10

CPC分类号： A61B17/0401 ,  A61B17/0469 ,  A61B17/0487 ,  A61B17/06066 ,  A61B17/064 ,  A61B17/08 ,  A61B17/10 ,  A61B17/29 ,  A61B2017/00349 ,  A61B2017/00867 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0445 ,  A61B2017/0446 ,  A61B2017/045 ,  A61B2017/0451 ,  A61B2017/0454 ,  A61B2017/0456 ,  A61B2017/0458 ,  A61B2017/0459 ,  A61B2017/0461 ,  A61B2017/0462 ,  A61B2017/0464 ,  A61B2017/0475 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/081 ,  A61B2017/3488

摘要： Needle assemblies for tissue manipulation are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. A needle deployment assembly is deployable through the tissue manipulation assembly via a handle assembly, through the tubular member, and into or through tissue. An elongate pusher is translationally disposed within a sheath of the needle deployment assembly and can be urged distally for deploying an anchor assembly from the sheath distal end. The anchor assembly is positioned distally of the pusher within the sheath.

摘要翻译： 用于组织操作的针组件在本文中描述。 在组织折叠在患者体内产生时，组织操作组件通常可以具有细长的管状构件，可滑动地设置穿过管状构件的接合构件和适于通过螺旋构件接合组织的远端，组织稳定构件 所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。 针部署组件可经由手柄组件穿过组织操纵组件展开，穿过管状构件，并且进入或穿过组织。 细长的推动器平移地设置在针展开组件的护套内，并且可以向远侧推动以从护套远端展开锚固组件。 锚固组件位于鞘内的推动器的远侧。

公开(公告)号：US07601159B2

公开(公告)日：2009-10-13

申请号：US10955244

申请日：2004-09-30

申请人： Richard C. Ewers ,  Tracy D. Maahs ,  Cang C. Lam ,  Vahid Saadat ,  Chris Rothe

发明人： Richard C. Ewers ,  Tracy D. Maahs ,  Cang C. Lam ,  Vahid Saadat ,  Chris Rothe

IPC分类号： A61B17/03

CPC分类号： A61B17/0401 ,  A61B17/0469 ,  A61B17/0487 ,  A61B17/06066 ,  A61B17/064 ,  A61B17/08 ,  A61B17/10 ,  A61B17/29 ,  A61B2017/00867 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0445 ,  A61B2017/0446 ,  A61B2017/045 ,  A61B2017/0451 ,  A61B2017/0454 ,  A61B2017/0456 ,  A61B2017/0458 ,  A61B2017/0459 ,  A61B2017/0461 ,  A61B2017/0462 ,  A61B2017/0464 ,  A61B2017/0475 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/081 ,  A61B2017/3488

摘要： Interlocking tissue anchor apparatus and methods are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. Anchor assemblies can be delivered via the tissue manipulation assembly into or through the tissue. The anchors can incorporate various temporary interlocking features or spacing elements between one another to ensure that an anchor is not prematurely ejected from the needle assembly. This allows the anchor assembly to be advanced distally as well as withdrawn proximally within a deployment sheath while avoiding inadvertently ejecting an anchor.

摘要翻译： 本文描述了联锁组织锚装置和方法。 在组织折叠在患者体内产生时，组织操作组件通常可以具有细长的管状构件，可滑动地设置穿过管状构件的接合构件和适于通过螺旋构件接合组织的远端，组织稳定构件 所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。 锚固组件可以经由组织操纵组件输送到组织或穿过组织。 锚固件可以在彼此之间结合各种临时互锁特征或间隔元件，以确保锚不会从针组件过早地弹出。 这允许锚固组件在部署护套内远端地向远侧推进，同时避免无意中弹出锚固件。

公开(公告)号：US07520884B2

公开(公告)日：2009-04-21

申请号：US10841233

申请日：2004-05-07

申请人： Lee L. Swanstrom ,  Richard C. Ewers ,  Tracy D. Maahs ,  Eugene G. Chen ,  Vahid Saadat

发明人： Lee L. Swanstrom ,  Richard C. Ewers ,  Tracy D. Maahs ,  Eugene G. Chen ,  Vahid Saadat

IPC分类号： A61B17/08

CPC分类号： A61B17/00234 ,  A61B17/0401 ,  A61B17/085 ,  A61B17/1114 ,  A61B2017/0496 ,  A61B2017/081 ,  A61F5/0086

摘要： Methods for performing gastroplasty include reducing the effective volume or cross-sectional area of the stomach via approximation of gastric tissue. Such reduction preferably is achieved endoluminally, either with or without laparoscopic ports. In one variation, a sleeve, pouch, Magenstrasse and Mill, Vertical Banded Gastroplasty (“VBG”), etc.,is formed within the stomach by approximating opposing anterior and posterior segments or ridges of the stomach wall at locations inferior to the gastroesophageal junction. In another variation, opposing walls of the stomach are approximated at a plurality of substantially random locations to reduce an effective volume of the stomach. In yet another variation, both a sleeve and random approximations are formed, the random approximations preferably disposed in a portion of the stomach excluded by the sleeve. In still another variation, opposing walls of the stomach are approximated over significant lengths at random or specified locations.

摘要翻译： 进行胃成形术的方法包括通过胃组织的近似来减小胃的有效体积或横截面积。 这种减少优选是在腹腔镜下或腹腔镜下进行的。 在一个变型中，通过在胃壁下方的胃壁的相邻的前部和后部区段或脊部近似形成在胃内形成套筒，袋，Magenstrasse和Mill，垂直带状胃成形术（“VBG”）等 。 在另一个变型中，胃的相对壁在多个基本上随机的位置近似，以减少胃的有效体积。 在另一个变型中，形成套筒和随机近似，随机近似优选地设置在由套筒排除的胃的一部分中。 在另一个变体中，胃的相对的壁在随机或指定的位置处以相当长的长度近似。

公开(公告)号：US20090082623A1

公开(公告)日：2009-03-26

申请号：US11810850

申请日：2007-06-07

申请人： Chris A. Rothe ,  Vahid Saadat ,  Kevin H. Van Bladel

发明人： Chris A. Rothe ,  Vahid Saadat ,  Kevin H. Van Bladel

IPC分类号： A61B1/04

CPC分类号： A61B1/3137 ,  A61B1/00082 ,  A61B1/00089 ,  A61B1/00147 ,  A61B17/0057 ,  A61B17/064 ,  A61B2017/00243 ,  A61B2017/00579 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/0061 ,  A61B2017/00615 ,  A61B2017/00623 ,  A61B2017/0641

摘要： Visualization and treatment of tissue regions via percutaneous access methods and devices are described herein. The system may include a deployment catheter and an expandable imaging hood. In use, the hood may be introduced from outside the patient body through a percutaneous incision and advanced through a subxiphoid pathway, for example, to the heart where entry may be accomplished via an incision through the left atrial appendage. Once within the heart, the hood can be advanced to any chamber to visualize and/or treat tissue by placing the hood against the tissue to be imaged and pumping translucent fluids into the hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for treating the tissue of interest.

摘要翻译： 本文描述了通过经皮访问方法和装置对组织区域的可视化和治疗。 该系统可以包括展开导管和可扩展成像罩。 在使用中，引擎盖可以通过经皮切口从患者身体的外部引入，并穿过亚剑突途径，例如穿过左心耳通过切口进入心脏。 一旦在心脏内，通过将罩放置在待成像的组织上并将半透明流体泵入罩中直到流体移动任何血液，从而留下清晰的区域 要通过部署导管中的成像元件成像的组织。 此外，任何数量的治疗工具也可以通过展开导管并进入成像罩以用于感兴趣的组织。

公开(公告)号：US20080200821A1

公开(公告)日：2008-08-21

申请号：US12110585

申请日：2008-04-28

申请人： Vahid Saadat

发明人： Vahid Saadat

IPC分类号： A61B5/1495 ,  A61B5/0215

CPC分类号： A61B5/14542 ,  A61B5/1459 ,  A61B5/6848

摘要： Left atrial access apparatus and methods are described herein. Different parameters, such as oxygen saturation difference, between the left and right atrial chambers is utilized to guide a needle or catheter into a desired position within the heart. Various sensing elements can be utilized to detect the physiological parameter difference, such as oxygen levels, in the left atrium. The sensor can be carried by the needle, at its tip or along its body, and can measure the physiological parameter levels contained in the blood, fluid, or tissue.

摘要翻译： 本文描述了左心房接入装置和方法。 使用左心房和右心房之间的不同参数（例如氧饱和度差异）将针或导管引导到心脏内的期望位置。 可以使用各种感测元件来检测左心房中的生理参数差异，例如氧水平。 传感器可以由针头，其尖端或沿其身体携带，并且可以测量包含在血液，流体或组织中的生理参数水平。

公开(公告)号：US20080051812A1

公开(公告)日：2008-02-28

申请号：US11461740

申请日：2006-08-01

申请人： Greg Schmitz ,  Jefferey Bleam ,  Jefffrey L. Bleich ,  Roy Leguidleguid ,  Vahid Saadat

发明人： Greg Schmitz ,  Jefferey Bleam ,  Jefffrey L. Bleich ,  Roy Leguidleguid ,  Vahid Saadat

IPC分类号： A61B17/32

CPC分类号： A61B17/320016 ,  A61B17/1604 ,  A61B17/1611 ,  A61B17/1671 ,  A61B2017/003 ,  A61B2017/32004 ,  A61B2017/320069 ,  A61B2017/32007

摘要： A device for cutting tissue in a human body may include an elongate, hollow shaft having a proximal portion and a distal portion, a bundle of flexible wires slidably disposed within at least a portion of the shaft and having a proximal end and a distal end, and an actuator coupled with the proximal portion of the shaft and the proximal end of the bundle of wires. The distal end of the bundle may be configured to facilitate cutting of tissue, and the wires of the bundle may be at least partially free to move, relative to one another, to allow a cross-sectional shape of the bundle to differ along a length from the proximal to the distal end. The actuator may be configured to move the wires back and forth through the hollow shaft to cause the distal ends of the wires to cut tissue.

摘要翻译： 用于在人体中切割组织的装置可以包括具有近端部分和远侧部分的细长的中空轴，可滑动地设置在所述轴的至少一部分内并具有近端和远端的柔性线束， 以及与所述轴的近侧部分和所述电线束的近端耦合的致动器。 束的远端可以被配置为便于切割组织，并且束的线可以至少部分地相对于彼此自由移动，以允许束的横截面形状沿长度方向不同 从近端到远端。 致动器可以被配置为通过空心轴来回移动电线，以使电线的远端切割组织。

公开(公告)号：US20070287886A1

公开(公告)日：2007-12-13

申请号：US11687597

申请日：2007-03-16

申请人： Vahid Saadat

发明人： Vahid Saadat

IPC分类号： A61B1/04

CPC分类号： A61B1/005 ,  A61B1/0008 ,  A61B1/00082 ,  A61B1/00085 ,  A61B1/00089 ,  A61B1/015 ,  A61B1/018 ,  A61B1/04 ,  A61B5/0031 ,  A61B5/02007 ,  A61B5/6882 ,  A61B8/12 ,  A61B8/445 ,  A61B2018/0212

摘要： Tissue visualization and manipulation systems are described herein. Such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for treating the tissue region of interest.

摘要翻译： 本文描述了组织可视化和操纵系统。 这样的系统可以包括部署导管和可展开成扩展配置的附接成像罩。 在使用中，成像罩被放置在通常填充有不透明体液如血液的体腔中的待成像组织区域附近或邻近。 半透明或透明的液体（例如盐水）可被泵送到成像罩中，直到流体移动任何血液，从而留下通过展开导管中的成像元件成像的组织的清晰区域。 此外，任何数量的治疗工具也可以通过展开导管并进入成像罩以用于治疗感兴趣的组织区域。

公开(公告)号：US20070286440A1

公开(公告)日：2007-12-13

申请号：US11754823

申请日：2007-05-29

申请人： Amir Abolfathi ,  Vahid Saadat ,  Loc Phan

发明人： Amir Abolfathi ,  Vahid Saadat ,  Loc Phan

IPC分类号： H04R25/00

CPC分类号： H04R25/606 ,  A61C5/00 ,  A61C8/0093 ,  A61C8/0098 ,  B33Y70/00 ,  B33Y80/00 ,  H04R1/46 ,  H04R3/04 ,  H04R25/554 ,  H04R25/602 ,  H04R25/604 ,  H04R2225/31 ,  H04R2225/67 ,  H04R2420/07 ,  H04R2460/01 ,  H04R2460/13

摘要： Methods and apparatus for transmitting vibrations via an electronic and/or transducer assembly through a tooth or teeth are disclosed herein. The assembly may be attached, adhered, or otherwise embedded into or upon a removable oral appliance to form a hearing aid assembly. Such an oral appliance may be a custom-made device. The electronic and transducer assembly may receive incoming sounds either directly or through a receiver to process and amplify the signals and transmit the processed sounds via a vibrating transducer element coupled to a tooth or other bone structure, such as the maxillary, mandibular, or palatine bone structure.

摘要翻译： 本文公开了通过电子和/或换能器组件通过齿或齿传递振动的方法和装置。 组件可以附接，粘附或以其它方式嵌入到可移除的口腔器具中或之上，以形成助听器组件。 这种口腔器具可以是定制的装置。 电子和换能器组件可以直接或通过接收器接收输入声音，以处理和放大信号，并经由耦合到牙齿或其它骨结构（例如上颌骨，下颌骨或腭骨）的振动换能器元件传送经处理的声音 结构体。

公开(公告)号：US20070079924A1

公开(公告)日：2007-04-12

申请号：US11245538

申请日：2005-10-06

申请人： Vahid Saadat ,  Arvin Chang

发明人： Vahid Saadat ,  Arvin Chang

IPC分类号： B32B37/00

CPC分类号： B29C53/50 ,  A61B1/0011 ,  A61B1/00142 ,  A61B1/31 ,  B29C53/82 ,  B29C65/16 ,  B29C65/18 ,  B29C65/224 ,  B29C65/48 ,  B29C65/5042 ,  B29C65/5092 ,  B29C65/7847 ,  B29C66/1122 ,  B29C66/1142 ,  B29C66/14 ,  B29C66/4322 ,  B29C66/49 ,  B29C66/61 ,  B29C66/63 ,  B29C66/632 ,  B29C66/71 ,  B29C66/8122 ,  B29C66/81821 ,  B29C66/81871 ,  B29C66/8322 ,  B29C66/83411 ,  B29C66/83413 ,  B29C66/836 ,  B29C2793/009 ,  B29K2995/0092 ,  B29L2031/753 ,  Y10T156/1013 ,  Y10T156/1038 ,  Y10T428/13 ,  B29K2909/02

摘要： Flexible tubular liner coating systems are described herein. A method for coating and forming the flexible tubular inner liner may comprise, in one example, coating at least a first surface of a flexible elongate strip having a first and a second edge and then bringing the first and second edges of the flexible elongate strip into proximity of one another. Once the edges are brought towards one another, they may be joined such that a flexible tubular liner is formed having the coated first surface formed as an inner surface of the flexible tubular liner. Flexible tubular liner coating systems are described herein. A method for coating and forming the flexible tubular inner liner may comprise, in one example, coating at least a first surface of a flexible elongate strip having a first and a second edge and then bringing the first and second edges of the flexible elongate strip into proximity of one another. Once the edges are brought towards one another, they may be joined such that a flexible tubular liner is formed having the coated first surface formed as an inner surface of the flexible tubular liner.

摘要翻译： 本文描述了柔性管状衬里涂覆系统。 在一个实例中，涂覆和形成柔性管状内衬的方法可以包括具有第一和第二边缘的柔性细长带的至少第一表面，然后将柔性细长带的第一和第二边缘带入 彼此接近。 一旦边缘彼此接合，它们可以被接合，使得形成柔性管状衬垫，其具有形成为柔性管状衬垫的内表面的涂覆的第一表面。 本文描述了柔性管状衬里涂覆系统。 在一个实例中，涂覆和形成柔性管状内衬的方法可以包括具有第一和第二边缘的柔性细长带的至少第一表面，然后将柔性细长带的第一和第二边缘带入 彼此接近。 一旦边缘彼此接合，它们可以被接合，使得形成柔性管状衬垫，其具有形成为柔性管状衬垫的内表面的涂覆的第一表面。