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公开(公告)号：US20090082623A1
公开(公告)日：2009-03-26
申请号：US11810850
申请日：2007-06-07
IPC分类号： A61B1/04
CPC分类号： A61B1/3137 , A61B1/00082 , A61B1/00089 , A61B1/00147 , A61B17/0057 , A61B17/064 , A61B2017/00243 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/0061 , A61B2017/00615 , A61B2017/00623 , A61B2017/0641
摘要： Visualization and treatment of tissue regions via percutaneous access methods and devices are described herein. The system may include a deployment catheter and an expandable imaging hood. In use, the hood may be introduced from outside the patient body through a percutaneous incision and advanced through a subxiphoid pathway, for example, to the heart where entry may be accomplished via an incision through the left atrial appendage. Once within the heart, the hood can be advanced to any chamber to visualize and/or treat tissue by placing the hood against the tissue to be imaged and pumping translucent fluids into the hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for treating the tissue of interest.
摘要翻译： 本文描述了通过经皮访问方法和装置对组织区域的可视化和治疗。 该系统可以包括展开导管和可扩展成像罩。 在使用中，引擎盖可以通过经皮切口从患者身体的外部引入，并穿过亚剑突途径，例如穿过左心耳通过切口进入心脏。 一旦在心脏内，通过将罩放置在待成像的组织上并将半透明流体泵入罩中直到流体移动任何血液，从而留下清晰的区域 要通过部署导管中的成像元件成像的组织。 此外，任何数量的治疗工具也可以通过展开导管并进入成像罩以用于感兴趣的组织。
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公开(公告)号：US10064540B2
公开(公告)日：2018-09-04
申请号：US11763399
申请日：2007-06-14
IPC分类号： A61B1/00 , A61B1/005 , A61B1/313 , A61B8/12 , A61B1/015 , A61B1/018 , A61B1/04 , A61B5/02 , A61B8/00
CPC分类号： A61B1/00089 , A61B1/0008 , A61B1/00082 , A61B1/00085 , A61B1/005 , A61B1/015 , A61B1/018 , A61B1/04 , A61B1/3137 , A61B5/02007 , A61B8/12 , A61B8/4472
摘要： Visualization apparatus and methods for transseptal access are described herein where intravascular access across a septal wall is facilitated via devices which provide for direct visual viewing of tissue area. Such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to the tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid can be pumped into the imaging hood until the fluid displaces any blood leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Any number of therapeutic tools or a guidewire can be passed through the catheter and into the imaging hood for crossing the septal wall and passing the guidewire or instruments therethrough.
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公开(公告)号：US09220402B2
公开(公告)日：2015-12-29
申请号：US11810850
申请日：2007-06-07
CPC分类号： A61B1/3137 , A61B1/00082 , A61B1/00089 , A61B1/00147 , A61B17/0057 , A61B17/064 , A61B2017/00243 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/0061 , A61B2017/00615 , A61B2017/00623 , A61B2017/0641
摘要： Visualization and treatment of tissue regions via percutaneous access methods and devices are described herein. The system may include a deployment catheter and an expandable imaging hood. In use, the hood may be introduced from outside the patient body through a percutaneous incision and advanced through a subxiphoid pathway, for example, to the heart where entry may be accomplished via an incision through the left atrial appendage. Once within the heart, the hood can be advanced to any chamber to visualize and/or treat tissue by placing the hood against the tissue to be imaged and pumping translucent fluids into the hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for treating the tissue of interest.
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公开(公告)号：US06494844B1
公开(公告)日：2002-12-17
申请号：US09598124
申请日：2000-06-21
申请人： Kevin H. Van Bladel , Seth Stabinsky , Lisa Zindel , Glenn Foy , Paul Mikus
发明人： Kevin H. Van Bladel , Seth Stabinsky , Lisa Zindel , Glenn Foy , Paul Mikus
IPC分类号： A61B1000
CPC分类号： A61B18/02 , A61B10/0041 , A61B10/0283 , A61B2018/00291
摘要： A device for diagnosis and treatment of tumors and lesions within the body. A cannula adapted to apply suction through the lumen of the catheter to the tumor or lesion is described. The lumen has a self sealing valve through which a cryoprobe is inserted while the suction is being applied. The cryoprobe is then inserted into the lesion, and operated to ablate the lesion.
摘要翻译： 用于诊断和治疗体内肿瘤和病变的装置。 描述了适于将吸引通过导管的内腔的套管到肿瘤或病变。 管腔具有自密封阀，当施加抽吸时通过该自封闭阀插入冷冻探针。 然后将冷冻探针插入病变，并操作以烧蚀病变。
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公开(公告)号：US5902832A
公开(公告)日：1999-05-11
申请号：US700170
申请日：1996-08-20
CPC分类号： A61L27/26 , A61L27/52 , Y10S524/916
摘要： A synthesis method is set forth for forming a physiologically acceptable composition comprising a plurality of physiologically acceptable hydrogel particles which have been swollen in a water solution containing a low molecular weight water soluble organic compound, the solution having the ability to swell the particles. The concentration of the organic compound is such that the resulting particles can be inserted, without use of a carrier liquid utilizing a hand driven hypodermic syringe. The swollen hydrogel particles are substantially insoluble in body fluids. The method comprises contacting not fully swollen hydrogel particles with the organic compound and with water.
摘要翻译： 阐述了一种用于形成生理上可接受的组合物的合成方法，所述组合物包含在含有低分子量水溶性有机化合物的水溶液中溶胀的多个生理上可接受的水凝胶颗粒，该溶液具有使颗粒膨胀的能力。 有机化合物的浓度使得所得颗粒可以插入，而不使用手动皮下注射器的载体液体。 溶胀的水凝胶颗粒基本上不溶于体液。 该方法包括使完全溶胀的水凝胶颗粒与有机化合物和水接触。
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公开(公告)号：US5674241A
公开(公告)日：1997-10-07
申请号：US680717
申请日：1996-07-15
CPC分类号： A61F2/07 , A61L31/10 , A61F2/0077 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2250/0067
摘要： The present invention is a medical device such as a stent in the form of an expandable mesh with an expandable polymer layer thereon. The mesh is metal or plastic. The polymer may be any of a variety of expandable polymers, which either expand upon hydration, or expand without significant resistance. The invention may be used, for example, as an expandable biliary, vascular, endotracheal, esophageal, or prostatic device.
摘要翻译： 本发明是一种医疗装置，例如其上具有可膨胀聚合物层的可扩张网状的支架。 网格是金属或塑料。 聚合物可以是各种可膨胀聚合物中的任何一种，其在水合时膨胀或膨胀而没有显着的阻力。 本发明可以用作例如可扩张的胆管，血管，气管内，食管或前列腺装置。
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公开(公告)号：US20110066075A1
公开(公告)日：2011-03-17
申请号：US12883572
申请日：2010-09-16
IPC分类号： A61B10/00
CPC分类号： A61B10/0266 , A61B18/02 , A61B2010/0208 , A61B2018/0262 , A61B2018/0293 , H04L41/147 , H04L47/11 , H04L47/14
摘要： A device and method of use for securing and coring of tumors within the body during a biopsy of the tumor, specifically breast tumors. An adhesion probe for securing the tumor is described. The probe secures the tumor by piercing the tumor and providing a coolant to the distal tip to cool the tip. The cooled tip adheres to the tumor. A coring instrument adapted for cutting a core sample of the tumor is described. The instrument is provided with a cannula that can cut a core sample of the tumor. The instrument is adapted for use with the probe with the probe fitting within the cannula. The instrument can be used in conjunction with the probe to secure and core a sample of the tumor for biopsy.
摘要翻译： 用于在肿瘤活检期间，特别是乳腺肿瘤中用于确保和取出体内肿瘤的装置和方法。 描述了用于固定肿瘤的粘附探针。 探针通过刺穿肿瘤固定肿瘤，并向远端提供冷却剂以冷却末端。 冷却的尖端附着于肿瘤。 描述适于切割肿瘤的核心样本的取芯器械。 该仪器设置有可以切割肿瘤的核心样本的套管。 该仪器适用于带探头接头的探头与套管内的接头。 该仪器可以与探头一起使用，以固定和核心肿瘤样本进行活检。
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公开(公告)号：US06241744B1
公开(公告)日：2001-06-05
申请号：US09216629
申请日：1998-12-16
申请人： Mir A. Imran , Theodore C. Ormsby , Carole M. Sykes , Jeffrey S. Frisbie , Kevin H. Van Bladel , Scott A. McGill , Osamu Katoh
发明人： Mir A. Imran , Theodore C. Ormsby , Carole M. Sykes , Jeffrey S. Frisbie , Kevin H. Van Bladel , Scott A. McGill , Osamu Katoh
IPC分类号： A61B1722
CPC分类号： A61B8/4461 , A61B8/0833 , A61B8/0841 , A61B8/12 , A61B17/22 , A61B90/36 , A61B2017/00106 , A61B2017/22051 , A61B2017/22072 , A61M25/09041 , Y10S128/916
摘要： An apparatus for deploying a guidewire across a complex lesion in a vessel formed by a wall and normally having a lumen extending therethrough including an elongate flexible catheter having proximal and distal extremities and having a plurality of separate spaced apart lumens therein extending from the proximal extremity into a location at least adjacent the distal extremity. A handle is mounted on the proximal extremity of the flexible elongate catheter. A flexible elongate sheath is mounted on the catheter and has a proximal portion, a transition portion and a distal portion with the transition portion being in the vicinity of the distal extremity of the catheter. The sheath has a lumen therein extending from the proximal portion through the transition portion and through the distal portion. First and second devices are slidably mounted in the spaced-apart lumens of said catheter. The lumen in the distal portion of said sheath has a size so that it can accommodate only one at a time of the at least two devices.
摘要翻译： 一种用于在由壁形成的容器中的复杂病变部分上布置导丝的装置，并且通常具有延伸穿过其中的内腔，其包括具有近端和远端的细长柔性导管，并且具有多个独立间隔开的腔，其从近端延伸到第 至少邻近远端的位置。 手柄安装在柔性细长导管的近端上。 柔性细长护套安装在导管上并且具有近端部分，过渡部分和远端部分，其中过渡部分位于导管的远端附近。 护套具有内腔，其从近端部分延伸穿过过渡部分并且穿过远端部分。 第一和第二装置可滑动地安装在所述导管的间隔开的内腔中。 所述护套的远端部分中的内腔具有这样的尺寸，使得其仅能容纳至少两个装置中的一个。
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公开(公告)号：US5913818A
公开(公告)日：1999-06-22
申请号：US925967
申请日：1997-09-09
申请人： Fred H. Co , Kevin H. Van Bladel
发明人： Fred H. Co , Kevin H. Van Bladel
CPC分类号： A61B17/02 , A61B17/00008 , A61B17/0218 , A61B2017/00778 , A61B2017/320044 , A61B90/30 , A61B90/50
摘要： A self-supporting retractor for holding open an anatomic space for performing endoscopic surgical procedures. The retractor includes a substantially rigid elongate member, having proximal and distal ends, and having an arch shape or "C" cross-section, defining a passage and longitudinal working window along the retractor. The distal end is preferably rounded or streamlined to facilitate insertion along a dissected space with minimized tissue trauma, and may include a hooded portion enclosing the passage at the distal end. The elongate member may include radially-cooperating segments or self-retaining edges to maximize the area of the space held open by the retractor. The retractor may include a handle or a pivotable finger grip on the proximal end to manipulate the retractor during use, and/or a curved handle to tent the incision providing access to the dissected space. The retractor may also include a channel member for an endoscope, integrally formed or pivotally attached to the retractor.
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公开(公告)号：US5855615A
公开(公告)日：1999-01-05
申请号：US660127
申请日：1996-06-07
摘要： A composition for injecting into tissues surrounding the urethra or ureter. It comprises a plurality of physiologically acceptable solid polymer particles dispersed in a physiologically acceptable biodissipatable liquid carrier. The polymer comprises a hydrophilic component. The solid polymer particles are a glycerine insoluble poly(ethylene oxide) (PEO) polymer or copolymer or a mineral oil insoluble polyvinylpyrrolidone polymer or copolymer. The plurality of solid polymer particles are capable of hydrating and upon hydration of absorbing at least about 30% water and of swelling to a predetermined volume. The solid particles are substantially insoluble in body fluids and substantially insoluble in and non-swellable by the liquid carrier. The composition is especially suitable in treating patients with urinary incontinence and patients with vesicoureteral reflux via injection into the tissues around the urethra or ureter.
摘要翻译： 用于注射到尿道或输尿管周围组织的组合物。 它包含分散在生理上可接受的生物可分解液体载体中的多个生理可接受的固体聚合物颗粒。 聚合物包含亲水组分。 固体聚合物颗粒是甘油不溶性聚（环氧乙烷）（PEO）聚合物或共聚物或矿物油不溶性聚乙烯吡咯烷酮聚合物或共聚物。 多个固体聚合物颗粒能够水合并在水合时吸收至少约30％的水并膨胀至预定体积。 固体颗粒基本上不溶于体液，并且基本上不溶于液体载体并且不溶于液体载体。 该组合物特别适用于通过注射到尿道或输尿管周围的组织中治疗尿失禁患者和膀胱输尿管反流患者。
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