专利检索 ap:("Lain-Yen Hu" OR "Thomas Charles Malone" OR "Laszlo Nadasdi" OR "Michael Francis Rafferty" OR "Todd Robert Ryder" OR "Diego F. Silva" OR "Yuntao Song" OR "Balazs G. Szoke" OR "Laszlo Urge") AND inv:"Yuntao Song" 第 2 页

11.

发明授权
Pyrrole-based HMG-CoA reductase inhibitors 失效
标题翻译：基于吡咯的HMG-CoA还原酶抑制剂

公开(公告)号：US07250444B2

公开(公告)日：2007-07-31

申请号：US10862844

申请日：2004-06-07

申请人： Robert Michael Kennedy , William Keun-Chan Park , Bruce David Roth , Yuntao Song , Bharat K. Trivedi

发明人： Robert Michael Kennedy , William Keun-Chan Park , Bruce David Roth , Yuntao Song , Bharat K. Trivedi

IPC分类号： A61K31/40 , C07D207/00

CPC分类号： C04B35/632 , C07C303/40 , C07C311/13 , C07D207/33 , C07D207/34 , C07D207/36 , C07D319/06 , C07D401/04 , C07D401/12 , C07D403/12 , C07D405/06 , C07D405/12 , C07D405/14 , C07D413/12 , C07D413/14

摘要： HMGCo-A reductase inhibitor compounds useful as hypocholesterolemic and hypolipidemic compounds are provided. Also provided are pharmaceutical compositions of the compounds. Methods of making and methods of using the compounds are also provided.

摘要翻译： 提供了可用作低胆固醇血症和降血脂化合物的HMGCo-A还原酶抑制剂化合物。还提供了化合物的药物组合物。还提供了制备方法和使用该化合物的方法。

12.

发明申请
Novel pyrroles and imidazoles 审中-公开
标题翻译：新颖的吡咯和咪唑

公开(公告)号：US20060287378A1

公开(公告)日：2006-12-21

申请号：US11389664

申请日：2006-03-24

申请人： Gary Bolton , Daniel Bowles , David Boyles , Walter Howard , Richard Hutchings , Robert Kennedy , William Park , Yuntao Song , Bharat Trivedi

发明人： Gary Bolton , Daniel Bowles , David Boyles , Walter Howard , Richard Hutchings , Robert Kennedy , William Park , Yuntao Song , Bharat Trivedi

IPC分类号： A61K31/4178 , A61K31/4172 , C07D405/02 , C07D233/54

CPC分类号： C07D413/14 , A61K31/4172 , A61K31/4178 , A61K45/06 , C07D207/34 , C07D207/36 , C07D233/64 , C07D233/66 , C07D233/84 , C07D233/90 , C07D401/04 , C07D401/12 , C07D403/06 , C07D405/06 , C07D405/14 , C07D413/12 , A61K2300/00

摘要： Novel imidazoles and novel pyrroles are provided. Also provided are pharmaceutical compositions, methods of making and methods of using the compounds.

摘要翻译： 提供了新颖的咪唑和新颖的吡咯。还提供了药物组合物，制备方法和使用该化合物的方法。

13.

发明申请
Novel imidazoles 审中-公开
标题翻译：新型咪唑

公开(公告)号：US20050239857A1

公开(公告)日：2005-10-27

申请号：US11105288

申请日：2005-04-13

申请人： Gary Bolton , Daniel Bowles , David Boyles , Walter Howard , Richard Hutchings , Robert Kennedy , William Park , Toni-Jo Poel , Yuntao Song

发明人： Gary Bolton , Daniel Bowles , David Boyles , Walter Howard , Richard Hutchings , Robert Kennedy , William Park , Toni-Jo Poel , Yuntao Song

IPC分类号： A61K31/4172 , A61K31/4178 , A61K45/06 , C07D233/54 , C07D233/66 , C07D233/84 , C07D233/90 , C07D401/04 , C07D401/12 , C07D403/06 , C07D405/06 , C07D405/14 , C07D413/12 , C07D413/14 , C07D43/02

CPC分类号： C07D413/14 , A61K31/4172 , A61K31/4178 , A61K45/06 , C07D207/34 , C07D207/36 , C07D233/64 , C07D233/66 , C07D233/84 , C07D233/90 , C07D401/04 , C07D401/12 , C07D403/06 , C07D405/06 , C07D405/14 , C07D413/12 , A61K2300/00

摘要： Novel imidazoles are provided. The compounds are useful as HMGCo-A Reductase Inhibitor. Also provided are pharmaceutical compositions of the compounds. Methods of making and methods of using the compounds are also provided.

摘要翻译： 提供新的咪唑。该化合物可用作HMGCo-A还原酶抑制剂。还提供了化合物的药物组合物。还提供了制备方法和使用该化合物的方法。

14.

发明申请
N-alkyl pyrroles as HMG-CoA reductase inhibitors 审中-公开
标题翻译： N-烷基吡咯酮作为HMG-CoA还原酶抑制剂

公开(公告)号：US20050154042A1

公开(公告)日：2005-07-14

申请号：US11002821

申请日：2004-12-02

申请人： Larry Bratton , Xue-Min Cheng , Chitase Lee , Steven Miller , Jeffrey Pfefferkorn , Toni-Jo Poel , Roderick Sorenson , Yuntao Song , Kuai-Lin Sun , Bharat Trivedi , Paul Unangst

发明人： Larry Bratton , Xue-Min Cheng , Chitase Lee , Steven Miller , Jeffrey Pfefferkorn , Toni-Jo Poel , Roderick Sorenson , Yuntao Song , Kuai-Lin Sun , Bharat Trivedi , Paul Unangst

IPC分类号： A61K31/40 , C07D207/34 , C07D207/46 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/06 , C07D403/12 , C07D405/06 , C07D413/12

CPC分类号： C07D207/34 , C04B35/632 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/06 , C07D403/12 , C07D405/06 , C07D413/12

摘要： HMGCo-A reductase inhibitor compounds useful as hypocholesterolemic and hypolipidemic compounds are provided. Also provided are pharmaceutical compositions of the compounds. Methods of making and methods of using the compounds are also provided.

摘要翻译： 提供了可用作低胆固醇血症和降血脂化合物的HMGCo-A还原酶抑制剂化合物。还提供了化合物的药物组合物。还提供了制备方法和使用该化合物的方法。

15.

发明申请
Novel pyrrole-based HMG-CoA reductase inhibitors 失效
标题翻译：新型吡咯基HMG-CoA还原酶抑制剂

公开(公告)号：US20050043364A1

公开(公告)日：2005-02-24

申请号：US10862844

申请日：2004-06-07

申请人： Robert Kennedy , William Park , Bruce Roth , Yuntao Song , Bharat Trivedi

发明人： Robert Kennedy , William Park , Bruce Roth , Yuntao Song , Bharat Trivedi

IPC分类号： C07C303/40 , C07C311/13 , C07D207/32 , C07D207/33 , C07D207/34 , C07D207/36 , C07D319/06 , C07D401/04 , C07D401/12 , C07D403/12 , C07D405/06 , C07D405/12 , C07D405/14 , C07D413/12 , C07D413/14 , A61K31/4439 , A61K31/4015 , C07D43/02

CPC分类号： C04B35/632 , C07C303/40 , C07C311/13 , C07D207/33 , C07D207/34 , C07D207/36 , C07D319/06 , C07D401/04 , C07D401/12 , C07D403/12 , C07D405/06 , C07D405/12 , C07D405/14 , C07D413/12 , C07D413/14

摘要： 50 HMGCo-A reductase inhibitor compounds useful as hypocholesterolemic and hypolipidemic compounds are provided. Also provided are pharmaceutical compositions of the compounds. Methods of making and methods of using the compounds are also provided.

摘要翻译： 提供了可用作低胆固醇血症和降血脂化合物的50种HMGCo-A还原酶抑制剂化合物。还提供了化合物的药物组合物。还提供了制备方法和使用该化合物的方法。

16.

发明授权
MCP-1 receptor antagonists and methods of use thereof 失效
标题翻译： MCP-1受体拮抗剂及其使用方法

公开(公告)号：US07067538B2

公开(公告)日：2006-06-27

申请号：US10442917

申请日：2003-05-21

申请人： Larry D. Bratton , Alexander J. Bridges , David T. Connor , Steven R. Miller , Yuntao Song , Kuai-Lin Sun , Bharat K. Trivedi , Paul C. Unangst

发明人： Larry D. Bratton , Alexander J. Bridges , David T. Connor , Steven R. Miller , Yuntao Song , Kuai-Lin Sun , Bharat K. Trivedi , Paul C. Unangst

IPC分类号： A01N43/40 , A61K31/44

CPC分类号： C07C311/03 , C07C311/27 , C07C317/18 , C07C317/24 , C07C317/28 , C07C317/44 , C07D213/50 , C07D233/64 , C07D239/26 , C07D261/08 , C07D263/32 , C07D277/10 , C07D277/26 , C07D307/46 , C07D307/71 , C07D307/80 , C07D333/22 , C07D333/38 , C07D333/44 , C07D413/04

摘要： The present invention relates to sulfones that are useful in the treatment of chemokine-mediated disorders. In certain embodiments, the present invention concerns the compounds that are MCP-1 receptor antagonists.

摘要翻译： 本发明涉及可用于治疗趋化因子介导的病症的砜。在某些实施方案中，本发明涉及作为MCP-1受体拮抗剂的化合物。

17.

发明授权
Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor 有权
标题翻译：功能化杂环作为趋化因子受体功能的调节剂及其使用方法

公开(公告)号：US06951848B2

公开(公告)日：2005-10-04

申请号：US10096361

申请日：2002-03-12

申请人： Geraldine C. B. Harriman , Kenneth G. Carson , Daniel L. Flynn , Michael E. Solomon , Yuntao Song , Bharat K. Trivedi , Bruce D. Roth , Christine N. Kolz , Ly Pham , Kuai-lin Sun

发明人： Geraldine C. B. Harriman , Kenneth G. Carson , Daniel L. Flynn , Michael E. Solomon , Yuntao Song , Bharat K. Trivedi , Bruce D. Roth , Christine N. Kolz , Ly Pham , Kuai-lin Sun

IPC分类号： A61P31/18 , C07D209/42 , C07D235/26 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D487/04 , C07D491/04 , C07D491/08 , A61K31/33 , A61K31/40 , A61K31/405 , C07D209/04

CPC分类号： C07D401/04 , C07D209/42 , C07D235/26 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D487/04 , C07D491/04 , C07D491/08

摘要： Disclosed are novel compounds having the formula or a physiologically acceptable salt, amide, ester or prodrug thereof. The compounds can be used to modulate (antagonize, agonize) chemokine receptor function. Also disclosed is a method for treating a patient having an inflammatory disease and/or viral infection comprising administering an effective amount of a compound of Formula I. In particular embodiments, the invention is a method for treating a patient infected with HIV.

摘要翻译： 公开了具有下式的新化合物或其生理上可接受的盐，酰胺，酯或前药。该化合物可用于调节（拮抗，激动）趋化因子受体功能。还公开了一种治疗患有炎性疾病和/或病毒感染的患者的方法，其包括施用有效量的式I化合物。在具体实施方案中，本发明是用于治疗感染HIV的患者的方法。

18.

发明授权
Fused pyridine derivatives 有权
标题翻译：融合吡啶衍生物

公开(公告)号：US08680089B2

公开(公告)日：2014-03-25

申请号：US13522304

申请日：2011-01-17

申请人： Zhenhua Huang , Yan Zhang , Yuntao Song

发明人： Zhenhua Huang , Yan Zhang , Yuntao Song

IPC分类号： C07D471/04 , A61K31/437 , A61K31/4545 , A61K31/4745 , A61K31/496 , A61K31/5377 , A61K31/55 , A61K31/551 , A61P3/06 , A61P3/08 , A61P3/10 , C07D498/04 , C07D513/04

CPC分类号： C07D471/04 , C07D498/04 , C07D513/04

摘要： Fused pyridine derivatives shown as the general formula (I), and their pharmaceutically acceptable salts, stereoisomers or solvates thereof are disclosed, which belong to the technical field of medicines. The R1, R2, R3, Q, X and Y substituents in formula (I) are defined as in the description. Also disclosed are the preparation methods, pharmaceutical compositions comprising the compounds and uses of the compounds in the manufacture of the medicine for the treatment and/or prevention of noninsulin-dependent diabetes, hyperglycemia, hyperlipidemia and insulin resistance.

摘要翻译： 公开了以通式（I）表示的稠合吡啶衍生物及其药学上可接受的盐，立体异构体或溶剂化物，属于药物技术领域。式（I）中的R 1，R 2，R 3，Q，X和Y取代基如描述中所定义。还公开了制备方法，包含该化合物的药物组合物和该化合物在制备用于治疗和/或预防非胰岛素依赖型糖尿病，高血糖，高脂血症和胰岛素抵抗的药物中的用途。