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公开(公告)号：US20210190778A1
公开(公告)日：2021-06-24
申请号：US17132380
申请日：2020-12-23
发明人： Anahit AGHVANYAN , Eli N. GLEZER , John KENTEN , George SIGAL , Martin STENGELIN
IPC分类号： G01N33/543 , G01N33/569 , G01N33/53 , G01N33/533 , C12Q1/6804 , G01N21/66 , G01N21/76 , G01N21/77 , G01N33/58
摘要： The present invention is directed to methods for improving assay specificity and performance in binding assays.
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公开(公告)号：US20230407380A1
公开(公告)日：2023-12-21
申请号：US18320411
申请日：2023-05-19
发明人： Eli N. GLEZER , John H. KENTEN
IPC分类号： C12Q1/6844 , G01N33/543 , C12Q1/682 , C12Q1/6837 , C12Q1/6848 , C12Q1/6804 , G01N33/542
CPC分类号： C12Q1/6844 , G01N33/54306 , C12Q1/682 , C12Q1/6837 , G01N2458/10 , C12Q1/6804 , G01N33/542 , C12Q2531/125 , C12Q2533/107 , C12Q1/6848
摘要： The present invention is directed to methods for reducing cross-reactivity between species employed in multiplexed immunoassays.
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公开(公告)号：US20220357318A1
公开(公告)日：2022-11-10
申请号：US17813965
申请日：2022-07-21
发明人： Anahit AGHVANYAN , Eli N. GLEZER , John KENTEN , George SIGAL , Martin STENGELIN , David ROUTENBERG
IPC分类号： G01N33/543 , C12Q1/6832 , C12Q1/6837 , C12Q1/6844
摘要： The present invention is directed to methods for improving assay specificity and performance in binding assays.
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公开(公告)号：US20210339243A1
公开(公告)日：2021-11-04
申请号：US17378294
申请日：2021-07-16
发明人： Eli N. GLEZER , Bandele Jeffrey-Coker , Jeffery D. Debad , Sudeep M. Kumar , George B. Sigal , Bisbert Spieles , Michael Tsionsky , Michael Warnock
IPC分类号： B01L3/00 , G01N33/543 , G01N33/53
摘要： We describe assay modules (e.g., assay plates, cartridges, multi-well assay plates, reaction vessels, etc.), processes for their preparation, and method of their use for conducting assays. Reagents may be present in free form or supported on solid phases including the surfaces of compartments (e.g., chambers, channels, flow cells, wells, etc.) in the assay modules or the surface of colloids, beads, or other particulate supports. In particular, dry reagents can be incorporated into the compartments of these assay modules and reconstituted prior to their use in accordance with the assay methods. A desiccant material may be used to maintain and stabilize these reagents in a dry state.
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公开(公告)号：US20190277855A1
公开(公告)日：2019-09-12
申请号：US16420724
申请日：2019-05-23
发明人： Charles M. CLINTON , Eli N. GLEZER , Bandele JEFFREY-COKER , Sandor L. KOVACS , Sudeep M. KUMAR , George SIGAL , Carl STEVENS , Michael VOCK
摘要： We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
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公开(公告)号：US20190187060A1
公开(公告)日：2019-06-20
申请号：US16270062
申请日：2019-02-07
发明人： Charles M. CLINTON , Eli N. GLEZER , Sharon WEST , George SIGAL , Carl STEVENS , Michael L. VOCK
CPC分类号： G01N21/76 , G01N21/69 , G01N35/0092 , G01N35/028 , G01N35/1079 , G01N2035/0425 , Y10T436/114165
摘要： We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
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公开(公告)号：US20170089892A1
公开(公告)日：2017-03-30
申请号：US15311309
申请日：2015-05-15
发明人： Anahit AGHVANYAN , Eli N. GLEZER , John KENTEN , George SIGAL , Martin STENGELIN , David ROUTENBERG
IPC分类号： G01N33/543 , C12Q1/68
CPC分类号： G01N33/54306 , C12Q1/6804 , C12Q1/6832 , C12Q1/6837 , C12Q1/6844 , C12Q2525/197 , C12Q2531/125 , C12Q2563/107 , C12Q2565/514
摘要： The present invention is directed to methods for improving assay specificity and performance in binding assays.
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