公开(公告)号：US08354188B2

公开(公告)日：2013-01-15

申请号：US11887225

申请日：2006-03-10

申请人： Yasuo Takano ,  Naoki Imachi ,  Seiji Yoshimura ,  Shin Fujitani ,  Satoshi Nishikawa ,  Shinji Bessyo

发明人： Yasuo Takano ,  Naoki Imachi ,  Seiji Yoshimura ,  Shin Fujitani ,  Satoshi Nishikawa ,  Shinji Bessyo

IPC分类号： H01M2/16 ,  H01M2/08

CPC分类号： H01M10/0525 ,  H01M10/0565 ,  H01M10/058 ,  H01M10/0587 ,  H01M2300/0082 ,  Y02T10/7011 ,  Y10T29/49108

摘要： A polymer for bonding the positive electrode and negative electrode of a lithium secondary battery, which includes a positive electrode, a negative electrode and an electrolyte solution, with a separator arranged between the positive electrode and the negative electrode. The polymer contains a cationically polymerizable monomer unit (A), a monomer unit (B) providing affinity to the electrolyte solution, a monomer unit (C) providing poor solubility to the electrolyte solution, and a monomer unit (D) containing an anionic or nonionic hydrophilic group. This polymer can be obtained through radical polymerization such as emulsion polymerization or suspension polymerization, and is characterized by having a dissolution rate into a mixed solvent of ethylene carbonate (EC) and diethyl carbonate (DEC) [EC:DEC=5:5 (weight ratio)] of not more than 10% by weight.

摘要翻译： 一种用于将正极，负极和电解液溶解在锂二次电池的正极和负极上的聚合物，其中隔板配置在正极和负极之间。 聚合物含有阳离子聚合性单体单元（A），对电解质溶液提供亲和性的单体单元（B），对电解质溶液提供差的溶解度的单体单元（C）和含有阴离子或 非离子亲水基团。 该聚合物可以通过自由基聚合如乳液聚合或悬浮聚合获得，并且其特征在于具有在碳酸亚乙酯（EC）和碳酸二乙酯（DEC）的混合溶剂中的溶解速率[EC:DEC = 5:5（重量） 比）]为10重量％以下。

公开(公告)号：US08033271B2

公开(公告)日：2011-10-11

申请号：US12433963

申请日：2009-05-01

申请人： Seiji Yoshimura

发明人： Seiji Yoshimura

IPC分类号： F02M33/02 ,  F02M25/08

CPC分类号： F02M25/0809 ,  F02D41/0032 ,  F02D41/22 ,  F02D41/2422 ,  Y02T10/40

摘要： A diagnostic device for a fuel vapor treatment system having: a canister that captures fuel vapor generated in a fuel tank; a purge passage for purging fuel vapor from the canister to an intake passage of an internal combustion engine; a purge valve provided in the purge passage to adjust a flow rate of fuel vapor; a processing device that depressurize an fuel vapor path extending from the fuel tank to the purge valve via the canister by a pump and performs a diagnostic processing for diagnosing a leak of fuel vapor from the fuel vapor path based on a change in pressure in the fuel vapor path during depressurization; and an angle detection device that detects an angle of inclination of the vehicle. The processing device determines, based on an inclination angle of the vehicle detected by the angle detection device, whether the diagnostic processing can be performed.

摘要翻译： 一种用于燃料蒸汽处理系统的诊断装置，具有：罐，其捕获在燃料箱中产生的燃料蒸气; 吹扫通道，用于将燃料蒸气从罐排出到内燃机的进气通道; 设置在净化通道中以调节燃料蒸气的流量的净化阀; 一种处理装置，其通过泵将经由所述罐从所述燃料箱延伸到所述排放阀的燃料蒸气路径减压，并且执行用于基于所述燃料中的压力变化来诊断来自所述燃料蒸气路径的燃料蒸气泄漏的诊断处理 减压过程中的蒸气路径; 以及检测车辆的倾斜角度的角度检测装置。 处理装置基于角度检测装置检测到的车辆的倾斜角度来判定是否能够进行诊断处理。

公开(公告)号：US20090246635A1

公开(公告)日：2009-10-01

申请号：US11887225

申请日：2006-03-10

申请人： Yasuo Takano ,  Naoki Imachi ,  Seiji Yoshimura ,  Shin Fujitani ,  Satoshi Nishikawa ,  Shinji Bessyo

发明人： Yasuo Takano ,  Naoki Imachi ,  Seiji Yoshimura ,  Shin Fujitani ,  Satoshi Nishikawa ,  Shinji Bessyo

IPC分类号： H01M4/58 ,  H01M4/82

CPC分类号： H01M10/0525 ,  H01M10/0565 ,  H01M10/058 ,  H01M10/0587 ,  H01M2300/0082 ,  Y02T10/7011 ,  Y10T29/49108

摘要： A polymer for bonding the positive electrode and negative electrode of a lithium secondary battery, which includes a positive electrode, a negative electrode and an electrolyte solution, with a separator arranged between the positive electrode and the negative electrode. The polymer contains a cationically polymerizable monomer unit (A), a monomer unit (B) providing affinity to the electrolyte solution, a monomer unit (C) providing poor solubility to the electrolyte solution, and a monomer unit (D) containing an anionic or nonionic hydrophilic group. This polymer can be obtained through radical polymerization such as emulsion polymerization or suspension polymerization, and is characterized by having a dissolution rate into a mixed solvent of ethylene carbonate (EC) and diethyl carbonate (DEC)[EC:DEC=5:5 (weight ratio)] of not more than 10% by weight.

摘要翻译： 一种用于将正极，负极和电解液溶解在锂二次电池的正极和负极上的聚合物，其中隔板配置在正极和负极之间。 聚合物含有阳离子聚合性单体单元（A），对电解质溶液提供亲和性的单体单元（B），对电解质溶液提供差的溶解度的单体单元（C）和含有阴离子或 非离子亲水基团。 该聚合物可以通过自由基聚合如乳液聚合或悬浮聚合获得，并且其特征在于具有在碳酸亚乙酯（EC）和碳酸二乙酯（DEC）的混合溶剂中的溶解速率[EC:DEC = 5:5（重量） 比）]为10重量％以下。

公开(公告)号：US07371842B2

公开(公告)日：2008-05-13

申请号：US10511270

申请日：2003-04-28

申请人： Hidenori Nakajima ,  Mitsuru Ohkubo ,  Seiji Yoshimura ,  Nobuya Nishio ,  Kaori Nishio

发明人： Hidenori Nakajima ,  Mitsuru Ohkubo ,  Seiji Yoshimura ,  Nobuya Nishio ,  Kaori Nishio

IPC分类号： C07H21/04 ,  C12P21/06 ,  C12N15/00 ,  C07K14/00

CPC分类号： C12N9/88 ,  C07K14/4702 ,  G01N2500/00

摘要： It is intended to provide a protein participating in the regulation of sugar production, a polynucleotide encoding the same, a method of screening a compound participating in the regulation of sugar production and a drug for treating or preventing diabetes which contains the compound participating in the regulation of sugar production. A polynucleotide encoding a protein specifically binding to a substance WF00144 is found out from rat liver cells and thus a protein participating in the regulation of sugar production and a polynucleotide encoding the same are provided. Moreover, a method and a substance relating to a method of treating and preventing diabetes are found out and thus a method of treating diabetes relating to the regulation of sugar production relating to the method of treating and preventing diabetes is provided.

摘要翻译： 目的在于提供参与糖生产调节的蛋白质，编码糖蛋白的多核苷酸，筛选参与糖生产调节的化合物的方法和用于治疗或预防糖尿病的药物，其含有参与调节的化合物 的糖生产。 从大鼠肝细胞中发现编码与物质WF00144特异性结合的蛋白质的多核苷酸，因此提供了参与糖产​​生调节的蛋白质和编码该多核苷酸的多核苷酸。 此外，发现了与治疗和预防糖尿病的方法有关的方法和物质，因此提供了治疗和预防糖尿病的方法中关于糖生产调节的糖尿病的治疗方法。

公开(公告)号：US20070181449A1

公开(公告)日：2007-08-09

申请号：US10586615

申请日：2004-01-19

申请人： Keiji Hamamoto ,  Seiji Yoshimura ,  Shitomi Tamaoki

发明人： Keiji Hamamoto ,  Seiji Yoshimura ,  Shitomi Tamaoki

IPC分类号： B65D25/08

CPC分类号： A61J1/2089 ,  A61J1/1425 ,  A61J1/2031 ,  A61J1/2051 ,  A61J1/2065 ,  B65D81/3211

摘要： This invention provides a container set for mixing at the time of administration allowing a secure mixing operation in administration without dripping chemicals by maintaining the sealed state of the mouth of liquid container particularly until the containers are connected to each other for mixing while storing two contents in the containers, respectively, wherein a tuber plug 5 is detachably fitted to the mouth part 4 of a vial 1 and a cap 30 is fitted to the mouth part 22 of the liquid container 2. The cap 30 has a first structure 31 fitted liquid-tightly to the mouth part 22 and a second structure 32 fitted liquid-tightly to the first structure 31 and having a connection port part 32a connectable liquid-tightly to the mouth part 4. The second structure 32 is movable from a first position where the internal space of the liquid container 2 is sealed from the outside air to a second position on the axial inner side of the first position, and when the second structure is positioned at the second position, the vial 1 connected to the connection port part 32a is allowed to communicate with the internal space of the liquid container 2.

摘要翻译： 本发明提供了一种用于在给药时混合的容器组，其允许通过维持液体容器的口部的密封状态，直到容器彼此连接以进行混合，同时将两种内容物保存在 容器，其中块塞5可拆卸地装配到小瓶1的口部4，并且帽30装配到液体容器2的口部22。 盖30具有与口部22液密配合的第一结构31和与第一结构31液密配合的第二结构32，并且具有与口部4液密地连接的连接口部32a。 第二结构32可以从液体容器2的内部空间从外部空气密封到第一位置的轴向内侧的第二位置的第一位置移动，并且当第二结构位于第二位置时 连接到连接端口部分32a的小瓶1允许与液体容器2的内部空间连通。

公开(公告)号：US07115117B2

公开(公告)日：2006-10-03

申请号：US10370266

申请日：2003-02-19

申请人： Yasuyuki Shiraishi ,  Keiji Hamamoto ,  Seiji Yoshimura

发明人： Yasuyuki Shiraishi ,  Keiji Hamamoto ,  Seiji Yoshimura

IPC分类号： A61B19/00 ,  B65D25/08 ,  B65D1/24 ,  A61J1/00

CPC分类号： A61J1/2089 ,  A61J1/10 ,  A61J1/1443 ,  A61J1/1468 ,  A61J1/1475 ,  A61J1/201 ,  A61J1/2051 ,  A61J1/2096

摘要： The present invention provides an infusion vessel, which is capable of separately containing a drug and a infusion liquid in a sterile manner and mixing the drug with the infusion liquid in a sterile manner by a simple operation for use, while ensuring the sterility of a connector thereof. The infusion vessel according to the present invention comprises a bag (2) for containing a infusion liquid, a two-mouth vial (3) for containing a drug, and a joint (4) connecting the bag and the vial. A lower mouth portion (33) of the vial (3) is sealed with a rubber plug (7). The joint (4) is air-tightly connected to a liquid outlet port (21) provided in a bottom portion of the bag (2), and extends downward. The joint (4) has an opening (46) for communication between the inside and the outside thereof. An O-ring (6) and an intermediate rubber plug (5) are respectively attached to the joint (4) above and below the opening (46), and fitted in the upper mouth portion (32) of the vial (3) in an axially movable manner.

摘要翻译： 本发明提供了一种输注容器，其能够以无菌方式单独容纳药物和输注液体，并且通过简单的使用操作以无菌方式将药物与输注液体混合，同时确保连接器的无菌性 其中。 根据本发明的输注容器包括用于容纳输液的袋（2），用于容纳药物的双口小瓶（3）和连接袋和小瓶的接头（4）。 小瓶（3）的下口部分（33）用橡胶塞（7）密封。 接头（4）气密地连接到设置在袋（2）底部的液体出口（21），并向下延伸。 接头（4）具有用于其内部和外部之间连通的开口（46）。 O形环（6）和中间橡胶塞（5）分别安装在开口（46）上方和下方的接头（4）上，并装配在小瓶（3）的上口部分（32）中 轴向可移动的方式。

公开(公告)号：US06436577B1

公开(公告)日：2002-08-20

申请号：US09380215

申请日：1999-08-26

申请人： Yoshinori Kida ,  Ryuji Ohshita ,  Seiji Yoshimura ,  Toshiyuki Nohma ,  Koji Nishio

发明人： Yoshinori Kida ,  Ryuji Ohshita ,  Seiji Yoshimura ,  Toshiyuki Nohma ,  Koji Nishio

IPC分类号： H01M458

CPC分类号： H01M4/525 ,  H01M10/0525 ,  H01M10/0569 ,  H01M2300/004

摘要： In a non-aqueous electrolyte secondary battery provided with a positive electrode 1, a negative electrode 2, and a non-aqueous electrolyte solution, a lithium-containing composite nickel oxide is used as a chief component of the positive electrode material for the positive electrode, a lithium-containing titanium oxide is used as a chief component of the negative electrode material for the negative electrode, and the solvent of the non-aqueous electrolyte solution contains a cyclic carbonic ester and a chain carbonic ester in such a manner that the cyclic carbonic ester and chain carbonic ester are contained in amounts of not less than 10% by volume of the whole solvent, respectively, and the total content of the cyclic carbonic ester and the chain carbonic ester is not less than 60% by volume of the whole solvent.

摘要翻译： 在设置有正极1，负极2和非水电解质溶液的非水电解质二次电池中，使用含锂复合氧化镍作为正极用正极材料的主要成分 使用含锂的氧化钛作为负极用负极材料的主要成分，非水电解液的溶剂含有环状碳酸酯和链状碳酸酯，使环状 碳酸酯和链状碳酸酯的含量分别为全部溶剂的10体积％以上，环状碳酸酯和链状碳酸酯的总量不低于整体的60体积％ 溶剂。

公开(公告)号：US20110105460A1

公开(公告)日：2011-05-05

申请号：US13002373

申请日：2009-07-02

申请人： Seiji Yoshimura ,  Noriyuki Kawano ,  Tomoaki Kawano ,  Daisuke Sasuga ,  Takanori Koike ,  Hideyuki Watanabe ,  Hiroki Fukudome ,  Nobuyuki Shiraishi ,  Ryosuke Munakata ,  Hiroaki Hoshii ,  Kayoko Mihara

发明人： Seiji Yoshimura ,  Noriyuki Kawano ,  Tomoaki Kawano ,  Daisuke Sasuga ,  Takanori Koike ,  Hideyuki Watanabe ,  Hiroki Fukudome ,  Nobuyuki Shiraishi ,  Ryosuke Munakata ,  Hiroaki Hoshii ,  Kayoko Mihara

IPC分类号： A61K31/4196 ,  C07D401/12 ,  A61K31/4439 ,  C07D249/08 ,  C07D403/12 ,  A61K31/506 ,  C07D413/12 ,  A61K31/422 ,  A61K31/4245 ,  A61K31/5377 ,  C07D417/12 ,  A61K31/541 ,  C07D405/12 ,  A61K31/427 ,  C07D413/14 ,  C07D409/04 ,  C07D403/10 ,  C07D471/04 ,  A61K31/437 ,  A61P3/10 ,  A61P25/24 ,  A61P25/18 ,  A61P25/28

CPC分类号： C07D249/08 ,  C07D401/04 ,  C07D401/12 ,  C07D403/04 ,  C07D403/12 ,  C07D405/12 ,  C07D413/12 ,  C07D413/14 ,  C07D417/04 ,  C07D417/10 ,  C07D417/12

摘要： [Problem] A compound, which can be used for preventing or treating diseases, in which 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is concerned, in particular, diabetes, insulin resistance, dementia, schizophrenia and depression, is provided.[Means for Solution] It was found that a triazole derivative, in which one of the 3- and 5-positions of the triazole ring has (di)alkylmethyl or cycloalkyl, each of which is substituted with —O— (aryl or a heterocyclic group, each of which may be substituted, or lower alkylene-cycloalkyl), and the other thereof has aryl, a heterocyclic group or cycloalkyl, each of which may be substituted, or a pharmaceutically acceptable salt thereof exhibits potent 11β-HSD1 inhibitory action. From the above, the triazole derivative of the present invention can be used for preventing or treating diabetes, insulin resistance, dementia, schizophrenia and depression.

摘要翻译： [问题]提供了一种可用于预防或治疗疾病的化合物，其中涉及11种β-羟基类固醇脱氢酶（11＆bgr-HSD1），特别是糖尿病，胰岛素抵抗，痴呆，精神分裂症和抑郁症 。 [解决方案]发现三唑环的3-和5-位之一具有（二）烷基甲基或环烷基的三唑衍生物，其各自被-O-（芳基或杂环） 基团，其各自可以被取代，或低级亚烷基 - 环烷基），另一个具有可以被取代的芳基，杂环基或环烷基，或其药学上可接受的盐显示出有效的11β-HSD1抑制作用 。 由上可知，本发明的三唑衍生物可用于预防或治疗糖尿病，胰岛素抵抗，痴呆，精神分裂症和抑郁症。

公开(公告)号：US20090277427A1

公开(公告)日：2009-11-12

申请号：US12433963

申请日：2009-05-01

申请人： Seiji Yoshimura

发明人： Seiji Yoshimura

IPC分类号： F02M33/02 ,  G01M3/04

CPC分类号： F02M25/0809 ,  F02D41/0032 ,  F02D41/22 ,  F02D41/2422 ,  Y02T10/40

摘要： A diagnostic device for a fuel vapor treatment system having: a canister that captures fuel vapor generated in a fuel tank; a purge passage for purging fuel vapor from the canister to an intake passage of an internal combustion engine; a purge valve provided in the purge passage to adjust a flow rate of fuel vapor; a processing device that depressurize an fuel vapor path extending from the fuel tank to the purge valve via the canister by a pump and performs a diagnostic processing for diagnosing a leak of fuel vapor from the fuel vapor path based on a change in pressure in the fuel vapor path during depressurization; and an angle detection device that detects an angle of inclination of the vehicle. The processing device determines, based on an inclination angle of the vehicle detected by the angle detection device, whether the diagnostic processing can be performed.

摘要翻译： 一种用于燃料蒸汽处理系统的诊断装置，具有：罐，其捕获在燃料箱中产生的燃料蒸气; 吹扫通道，用于将燃料蒸气从罐排出到内燃机的进气通道; 设置在净化通道中以调节燃料蒸气的流量的净化阀; 一种处理装置，其通过泵将经由所述罐从所述燃料箱延伸到所述排放阀的燃料蒸气路径减压，并且执行用于基于所述燃料中的压力变化来诊断来自所述燃料蒸气路径的燃料蒸气泄漏的诊断处理 减压过程中的蒸气路径; 以及检测车辆的倾斜角度的角度检测装置。 处理装置基于角度检测装置检测到的车辆的倾斜角度来判定是否能够进行诊断处理。

公开(公告)号：US07022812B2

公开(公告)日：2006-04-04

申请号：US10910614

申请日：2004-08-04

申请人： Seiji Yoshimura ,  Hiroshi Nakajima ,  Maruo Kamino ,  Nobuhiro Nishiguchi ,  Masahiro Imanishi

发明人： Seiji Yoshimura ,  Hiroshi Nakajima ,  Maruo Kamino ,  Nobuhiro Nishiguchi ,  Masahiro Imanishi

IPC分类号： C08G65/34

CPC分类号： H01M2/145 ,  C08G61/02 ,  C08G61/12 ,  C08G64/06 ,  C08G75/23 ,  C08L69/00 ,  C08L71/00 ,  C08L71/12 ,  C08L73/02 ,  C08L81/02 ,  H01M2/0222 ,  H01M2/08 ,  H01M2/1653 ,  H01M6/16 ,  H01M10/052 ,  H01M2300/0025 ,  H01M2300/0037

摘要： A lithium battery employs for a battery separator and a battery insulating packing and the like a battery polymeric material comprising repeating units wherein p-phenylene is combined with one type of group selected from the group composed of oxygen, a methylene group, an isopropylidene group, a carbonyl group, a carbonyldioxy group, a carboxylic acid anhydride group, an amide group, an ureylene group and a sulfonyl group, or a polymeric material comprising at least two types of repeating units wherein p-phenylene is combined with one type of group selected from the group composed of oxygen, a methylene group, an isopropylidene group, a carbonyl group, a carbonyldioxy group, a carboxylic acid anhydride group, an amide group, an ureylene group, a sulfonyl group, sulfur and a carbonyloxy group.