公开(公告)号：US20090177089A1

公开(公告)日：2009-07-09

申请号：US11969504

申请日：2008-01-04

Applicant: Assaf Govari ,  Andres Claudio Altmann ,  Yaron Ephrath ,  Yitzhack Schwartz

Inventor： Assaf Govari ,  Andres Claudio Altmann ,  Yaron Ephrath ,  Yitzhack Schwartz

IPC: A61B8/14

CPC classification number: A61B8/543 ,  A61B6/541 ,  A61B8/12 ,  A61B8/14 ,  G06T7/13 ,  G06T7/564 ,  G06T2207/10012 ,  G06T2207/10132 ,  G06T2207/30048

Abstract: A method for imaging of an anatomical structure includes acquiring a plurality of ultrasonic images of the anatomical structure. At least one of the images includes Doppler information. One or more contours of the anatomical structure are generated from the Doppler information. A three-dimensional image of the anatomical structure is reconstructed from the plurality of ultrasonic images, using the one or more contours.

Abstract translation: 用于对解剖结构进行成像的方法包括获取解剖结构的多个超声图像。 至少一幅图像包括多普勒信息。 解剖结构的一个或多个轮廓由多普勒信息产生。 使用一个或多个轮廓，从多个超声波图像重建解剖结构的三维图像。

公开(公告)号：US07536218B2

公开(公告)日：2009-05-19

申请号：US11182272

申请日：2005-07-15

Applicant: Assaf Govari ,  Andres Claudio Altmann ,  Yitzhack Schwartz ,  Yaron Ephrath

Inventor： Assaf Govari ,  Andres Claudio Altmann ,  Yitzhack Schwartz ,  Yaron Ephrath

IPC: A61B5/05

CPC classification number: A61B5/063 ,  A61B5/0035 ,  A61B5/0538

Abstract: A position sensing system includes a probe adapted to be introduced into a body cavity of a subject. The probe includes a magnetic field transducer and at least one probe electrodes. A control unit is configured to measure position coordinates of the probe using the magnetic field transducer. The control unit also measures an impedance between the at least one probe electrodes and one or more points on a body surface of the subject. Using the measured position coordinates, the control unit calibrates the measured impedance.

Abstract translation: 位置感测系统包括适于被引入被检体体腔的探头。 探头包括磁场换能器和至少一个探针电极。 控制单元被配置为使用磁场换能器来测量探头的位置坐标。 控制单元还测量至少一个探针电极与被检体的身体表面上的一个或多个点之间的阻抗。 使用测量的位置坐标，控制单元校准测量的阻抗。

公开(公告)号：US07367970B2

公开(公告)日：2008-05-06

申请号：US10706299

申请日：2003-11-11

Applicant: Assaf Govari ,  Yitzhack Schwartz

Inventor： Assaf Govari ,  Yitzhack Schwartz

IPC: A61B18/18

CPC classification number: A61B18/14 ,  A61B2017/00004 ,  A61B2018/00375

Abstract: A resonant circuit is incorporated in a stent, which implantable in a pulmonary vein using known cardiac catheterization techniques. When an external RF field is generated at the resonant frequency of the stent, RF energy is re-radiated by the stent toward electroconductive tissue in the wall of the pulmonary vein, and produces a circumferential conduction block. The stent can be made of biodegradable materials, so that it eventually is resorbed. Following an ablation procedure, the stent may be left in situ. Repeated ablation can be performed using the inserted stent until it has been determined that the desired lesions have been formed. Furthermore, the same stent can potentially be used even years after being inserted should the treated arrhythmia reoccur or a new arrhythmia develop, thereby possibly obviating the need for an invasive procedure at that future time.

Abstract translation: 谐振电路并入支架中，其可以使用已知的心脏导管插入技术植入肺静脉。 当在支架的共振频率处产生外部RF场时，RF能量被支架重新辐射到肺静脉壁中的导电组织，并产生周向传导阻滞。 支架可以由可生物降解的材料制成，使其最终被吸收。 在消融手术之后，支架可以留在原位。 可以使用插入的支架进行重复消融，直到确定已经形成所需的损伤为止。 此外，如果治疗的心律失常复发或新的心律失常发展，则在插入后几年可以使用相同的支架，从而可能消除在未来时间对侵入性手术的需要。

公开(公告)号：US20070043296A1

公开(公告)日：2007-02-22

申请号：US11195123

申请日：2005-08-02

Applicant: Yitzhack Schwartz

Inventor： Yitzhack Schwartz

IPC: A61B8/14

CPC classification number: A61B8/12 ,  A61B6/503 ,  A61B6/504 ,  A61B8/0891

Abstract: A method for treating atrial fibrillation in a heart of a patient includes placing an ultrasonic catheter in a first chamber of the heart; acquiring two-dimensional ultrasonic images of a second chamber of the heart and at least a portion of surrounding structures of the second chamber using the ultrasonic catheter placed in the first chamber; reconstructing a three-dimensional ultrasonic image based on the two-dimensional ultrasonic images; displaying the reconstructed three-dimensional ultrasonic image; identifying at least one key landmark on the reconstructed three-dimensional ultrasonic image; marking the least one key landmark on the reconstructed three-dimensional ultrasonic image; penetrating the septum for accessing the second chamber of the heart while using the marked at least one key landmark for guidance; positioning a sheath through the penetrated septum and within the second chamber of the heart; inserting an ablation catheter through the sheath and into the second chamber of the heart; and ablating a portion of the second chamber of the heart using the ablation catheter while under observation with the ultrasound catheter located in the first chamber of the heart.

Abstract translation: 用于治疗患者心脏中的心房颤动的方法包括将超声导管放置在心脏的第一腔室中; 使用放置在所述第一腔室中的超声波导管获取心脏的第二腔室的二维超声图像和所述第二腔室的至少一部分周围结构; 基于二维超声图像重建三维超声图像; 显示重建的三维超声图像; 识别所述重建的三维超声图像上的至少一个键标记; 标记重建的三维超声图像上的至少一个关键标记; 在使用标记的至少一个关键地标进行引导时穿透隔膜以进入心脏的第二腔室; 将鞘穿过穿透的隔膜并在心脏的第二腔内; 将消融导管穿过所述护套插入心脏的第二腔中; 以及在使用位于心脏的第一腔室内的超声导管进行观察的同时，使用消融导管消融心脏的第二腔室的一部分。

公开(公告)号：US06997924B2

公开(公告)日：2006-02-14

申请号：US10245613

申请日：2002-09-17

Applicant: Yitzhack Schwartz ,  Assaf Govari ,  Shlomo Ben-Haim ,  Uri Yaron ,  Marcia Leatham

Inventor： Yitzhack Schwartz ,  Assaf Govari ,  Shlomo Ben-Haim ,  Uri Yaron ,  Marcia Leatham

IPC: A61B18/18

CPC classification number: A61B18/24 ,  A61B2017/22051 ,  A61B2018/2272

Abstract: A catheter introduction apparatus provides an optical assembly for emission of laser light energy. In one application, the catheter and the optical assembly are introduced percutaneously, and transseptally advanced to the ostium of a pulmonary vein. An anchoring balloon is expanded to position a mirror near the ostium of the pulmonary vein, such that light energy is reflected and directed circumferentially around the ostium of the pulmonary vein when a laser light source is energized. A circumferential ablation lesion is thereby produced, which effectively blocks electrical propagation between the pulmonary vein and the left atrium.

Abstract translation: 导管引入装置提供用于发射激光能量的光学组件。 在一个应用中，导管和光学组件经皮引入，经皮递送到肺静脉的口。 锚固气囊被扩张以在靠近肺静脉的口处定位镜子，使得当激光源被激发时，光能被反射并周向地环绕肺静脉的口引导。 从而产生圆周消融损伤，其有效阻止肺静脉与左心房之间的电传播。

公开(公告)号：US06652464B2

公开(公告)日：2003-11-25

申请号：US09739062

申请日：2000-12-18

Applicant: Yitzhack Schwartz ,  Assaf Govari ,  Shlomo Ben-Haim ,  Joel Zilberstein ,  Louis J. Capezzuto

Inventor： Yitzhack Schwartz ,  Assaf Govari ,  Shlomo Ben-Haim ,  Joel Zilberstein ,  Louis J. Capezzuto

IPC: A61B502

CPC classification number: A61B5/6882 ,  A61B5/0031 ,  A61B5/0215 ,  A61B5/076 ,  A61B2560/0219 ,  A61B2562/0233 ,  A61B2562/046 ,  Y10S128/903

Abstract: A method for telemetrically measuring a parameter in a patient's heart comprises the steps of imaging the heart and identifying an implantation site in the heart. An opening is created in the tissue at the implantation site. A sensor comprising a housing, a membrane at one end of the housing wherein the membrane is deformable in response to the parameter, and a microchip positioned within the housing and operatively communicating with the membrane for transmitting a signal indicative of the parameter is provided. The sensor is placed in the opening and the parameter is telemetrically measured from outside of the patient's body based on the transmitted signal by the sensor. The sensor is also telemetrically powered from outside of the patient's body. A signal charging and reading device is placed outside of the patient's body for telemetric powering and signal reading with respect to the sensor. In an alternative embodiment, the sensor has a tapered distal end and a tissue piercing tip for direct implantation into tissue. Alternative embodiments of this sensor include helical threads on the tapered distal end for threading the sensor into tissue and a plurality of tissue barbs for direct and firm anchoring of the sensor in tissue.

公开(公告)号：US09370312B2

公开(公告)日：2016-06-21

申请号：US11845973

申请日：2007-08-28

Applicant: Yitzhack Schwartz ,  Meir Bar-Tal ,  Joshua Porath

Inventor： Yitzhack Schwartz ,  Meir Bar-Tal ,  Joshua Porath

IPC: A61B5/042 ,  A61B5/0408 ,  A61B5/053 ,  A61B5/00 ,  A61B18/00

CPC classification number: A61B5/0422 ,  A61B5/04085 ,  A61B5/0538 ,  A61B5/6805 ,  A61B2018/00839

Abstract: A reliable endocardial map is obtained by constructing a matrix relationship between a small number of endocardial points and a large number of external receiving points using a multi-electrode chest panel. Inversion of the matrix yields information allowing the endocardial map to be constructed. Subsequent maps are obtained noninvasively using the multi-electrode chest panel, applying new electrical signals to the matrix relationship, and again inverting the matrix to generate new endocardial electrical maps.

Abstract translation: 通过使用多电极胸板在少量心内膜点和大量外部接收点之间构建矩阵关系来获得可靠的心内膜图。 矩阵的反演产生允许构建心内膜图的信息。 使用多电极胸板非侵入性地获得随后的图，将新的电信号应用于矩阵关系，并且再次反转矩阵以产生新的心内膜电图。

公开(公告)号：US09101333B2

公开(公告)日：2015-08-11

申请号：US13295594

申请日：2011-11-14

Applicant: Yitzhack Schwartz

Inventor： Yitzhack Schwartz

IPC: A61B18/00 ,  A61B5/00 ,  A61N7/02 ,  A61B18/14 ,  A61B18/24 ,  A61B19/00 ,  A61B5/0452

CPC classification number: A61B5/7285 ,  A61B5/0452 ,  A61B5/046 ,  A61B18/1492 ,  A61B18/24 ,  A61B34/20 ,  A61B34/25 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2034/252 ,  A61B2090/065 ,  A61B2090/364 ,  A61N7/022

Abstract: Cardiac tissue ablation is carried out by defining first regions containing first locations including ganglionated plexi in a heart of a living subject, and inserting a probe into the heart. The method is further carried out by detecting electrical activity in the heart via electrodes on the distal portion of the probe, defining second regions having second locations, wherein the electrical activity exhibits a dominant frequency that is higher than a predefined threshold, defining third regions having third locations, wherein the electrical activity exhibits complex fractionated atrial electrograms, constructing an electroanatomical map of the heart that defines intersections of the first regions and at least one of the second regions and the third regions, selecting ablation sites within the intersections, and ablating cardiac tissue at the ablation sites.

Abstract translation: 通过在生物体的心脏中限定含有神经节丛的第一位置的第一区域，并将探针插入心脏来进行心脏组织消融。 通过在探针的远端部分上的电极检测心脏中的电活动来限定该方法，限定具有第二位置的第二区域，其中电活动表现出高于预定义阈值的主频率，限定第三区域具有 第三位置，其中所述电活动显示复杂的分级心房电图，构建定义所述第一区域和所述第二区域和所述第三区域中的至少一个的交叉点的心脏的电解剖图，选择所述交叉点内的消融位点，以及消融心脏 消融部位的组织。

公开(公告)号：US07996059B2

公开(公告)日：2011-08-09

申请号：US11370666

申请日：2006-03-08

Applicant: Joshua Porath ,  Yitzhack Schwartz

Inventor： Joshua Porath ,  Yitzhack Schwartz

IPC: A61B5/05 ,  A61B18/04 ,  A61H1/00

CPC classification number: A61B5/06 ,  A61B5/061 ,  A61B5/4233 ,  A61B5/6885 ,  A61B6/12 ,  A61B8/0833 ,  A61B2562/164

Abstract: A device for enhancing visualization of an esophagus when imaged by a visualization system includes a structure including material that is clearly visible when imaged by the visualization system. The structure is arranged, when inserted into the esophagus, to expand so as to conform to an inner surface of the esophagus in order to enhance a visualization quality of the surface when imaged by the visualization system. A cord attached to the structure is arranged to extend out of the esophagus so as to assist a removal of the device from the esophagus.

Abstract translation: 用于增强由可视化系统成像时食管可视化的装置包括包括当由可视化系统成像时清晰可见的材料的结构。 当插入到食道中时，该结构被布置成扩展以便与食管的内表面一致，以便在由可视化系统成像时增强表面的可视化质量。 安装在该结构上的绳索被布置成延伸出食道以协助从食道中移除该装置。

公开(公告)号：US20100069763A1

公开(公告)日：2010-03-18

申请号：US12211592

申请日：2008-09-16

Applicant: Assaf Govari ,  Yaron Ephrath ,  Yitzhack Schwartz

Inventor： Assaf Govari ,  Yaron Ephrath ,  Yitzhack Schwartz

IPC: A61B5/0215

CPC classification number: A61B5/0215 ,  A61B5/6846

Abstract: Pressure-sensing apparatus includes a sensor die, which is configured for percutaneous insertion through a wall of a blood vessel of a patient so as to generate an electrical signal that is responsive to a pressure in the blood vessel. A wire has a first end connected to the sensor die and a second end connected to an electronics package, which is configured for subcutaneous implantation and is connected via the wire to receive and process the electrical signal that is generated by the sensor die in order to provide an output that is indicative of the pressure.

Abstract translation: 压力感测装置包括传感器管芯，其被配置为经皮穿过患者的血管的壁，以产生响应于血管中的压力的​​电信号。 线具有连接到传感器管芯的第一端和连接到电子封装的第二端，电子封装构造成用于皮下植入，并且经由导线连接以接收和处理由传感器裸片产生的电信号，以便 提供一个表示压力的输出。