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    COLLECTING GAIT INFORMATION FOR EVALUATION AND CONTROL OF THERAPY
    17.
    发明申请
    COLLECTING GAIT INFORMATION FOR EVALUATION AND CONTROL OF THERAPY 审中-公开
    收集评估和治疗控制的评估信息

    公开(公告)号：US20140249600A1

    公开(公告)日：2014-09-04

    申请号：US14278821

    申请日：2014-05-15

    Applicant: Medtronic, Inc.

    Inventor： Kenneth T. Heruth ,  Keith A. Miesel ,  Gregory F. Molnar

    IPC: A61N1/36

    CPC classification number: A61B5/4836 ,  A61B5/0022 ,  A61B5/0031 ,  A61B5/031 ,  A61B5/0488 ,  A61B5/1038 ,  A61B5/112 ,  A61B5/1123 ,  A61B5/4082 ,  A61B5/4094 ,  A61B5/7246 ,  A61B5/7275 ,  A61B5/7282 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/7455 ,  A61B2562/0219 ,  A61M5/1723 ,  A61N1/36003 ,  A61N1/36067 ,  A61N1/36082 ,  A61N1/3615 ,  G06F19/00

    Abstract: A medical device delivers a therapy to a patient. The medical device or another device may periodically determine an activity level or gait parameter of the patient, and associate each determined level or parameter with a current therapy parameter set. A value of at least one activity metric is determined for each of a plurality of therapy parameter sets based on the activity levels or parameters associated with that therapy parameter set. Whether the patient is currently experiencing or anticipated to experience gait freeze caused by their neurological disorder, such as Parkinson's disease, may also be determined. Gait freeze events may be associated with current therapy parameters and used to determine activity metric values. In some examples, the activity metric associated with certain therapy parameters may be presented to a user.

    Abstract translation: 医疗设备向患者传递治疗。 医疗装置或另一装置可以周期性地确定患者的活动水平或步态参数，并将每个确定的水平或参数与当前治疗参数组相关联。 基于与该治疗参数组相关联的活动水平或参数，确定多个治疗参数组中的每一个的至少一个活动度量的值。 患者目前是否经历或预期会经历由神经障碍引起的步态冻结，如帕金森病，也可能被确定。 步态冻结事件可能与当前治疗参数相关联，并用于确定活动度量值。 在一些示例中，可以向用户呈现与某些治疗参数相关联的活动度量。

    Urgency Therapy with Neuromodulation and C-Afferent Nerve Desensitization
    18.
    发明申请
    Urgency Therapy with Neuromodulation and C-Afferent Nerve Desensitization 有权
    紧急治疗与神经调节和C传入神经脱敏

    公开(公告)号：US20140142549A1

    公开(公告)日：2014-05-22

    申请号：US13817486

    申请日：2011-08-16

    Applicant: Medtronic, Inc.

    Inventor： Xin Su ,  Gregory F. Molnar ,  Nelson E. Dwight

    IPC: A61N1/36 ,  A61K31/165

    CPC classification number: A61N1/36007 ,  A61K31/165 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2205/054 ,  A61M2210/1085 ,  A61N1/36057 ,  A61N1/3606 ,  A61N1/36071 ,  A61N1/36171 ,  G06F19/00 ,  G06F19/3468 ,  G06F19/3481

    Abstract: Systems (10), devices (16), and methods may be used for treating bladder dysfunction, such as urgency and pelvic pain. In one example, a method includes administering a pharmacological agent to a patient (14) in a dosage sufficient to desensitize a C-afferent nerve fiber of the patient. Additionally, the method includes delivering stimulation to activate a nerve fiber proximate to the C-afferent nerve fiber via an electrode (19A, 19B, 21A, 21B, 29A-29D) electrically coupled to an implantable medical device (16). In some examples, the nerve fiber may be different than the C-afferent nerve fiber, the stimulation of the nerve fiber may elicit an inhibitory physiological response related to voiding in the patient, and/or the stimulation substantially may not activate the C-afferent nerve fiber after desensitization of the nerve fiber via the administration of the pharmacological agent.

    Abstract translation: 系统（10），装置（16）和方法可用于治疗膀胱功能障碍，如紧急和盆腔疼痛。 在一个实例中，一种方法包括以足以使患者的C型传入神经纤维脱敏的剂量向患者（14）施用药理学试剂。 另外，该方法包括递送刺激以通过电耦合到可植入医疗装置（16）的电极（19A，19B，21A，21B，29A-29D）激活靠近C型传入神经纤维的神经纤维。 在一些实例中，神经纤维可能与C传入神经纤维不同，神经纤维的刺激可能引起与患者排尿有关的抑制性生理反应，和/或刺激基本上不能激活C传入 神经纤维通过施用药理学神经纤维脱敏后。

    PATIENT DIRECTED THERAPY CONTROL
    19.
    发明申请
    PATIENT DIRECTED THERAPY CONTROL 审中-公开
    患者指导治疗

    公开(公告)号：US20130131755A1

    公开(公告)日：2013-05-23

    申请号：US13740860

    申请日：2013-01-14

    Applicant: Medtronic, Inc.

    Inventor： Eric J. Panken ,  Timothy J. Denison ,  Gregory F. Molnar

    IPC: A61N1/36

    CPC classification number: A61N1/36139 ,  A61B5/048 ,  A61B5/4082 ,  A61B5/7475 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2210/0693 ,  A61N1/36014 ,  A61N1/36017 ,  A61N1/36021 ,  A61N1/36025 ,  A61N1/3605 ,  A61N1/3606 ,  A61N1/36071 ,  A61N1/36082 ,  A61N1/37252 ,  G06F3/015

    Abstract: A patient controls the delivery of therapy through volitional inputs that are detected by a biosignal within the brain. The volitional patient input may be directed towards performing a specific physical or mental activity, such as moving a muscle or performing a mathematical calculation. In one embodiment, a biosignal detection module monitors an electroencephalogram (EEG) signal from within the brain of the patient and determines whether the EEG signal includes the biosignal. In one embodiment, the biosignal detection module analyzes one or more frequency components of the EEG signal. In this manner, the patient may adjust therapy delivery by providing a volitional input that is detected by brain signals, wherein the volitional input may not require the interaction with another device, thereby eliminating the need for an external programmer to adjust therapy delivery. Example therapies include electrical stimulation, drug delivery, and delivery of sensory cues.

    Abstract translation: 患者通过由大脑内的生物信号检测到的输入量来控制治疗的传递。 患者的输入可以指向执行特定的身体或精神活动，例如移动肌肉或执行数学计算。 在一个实施例中，生物信号检测模块监测来自患者脑内的脑电图（EEG）信号，并确定EEG信号是否包括生物信号。 在一个实施例中，生物信号检测模块分析EEG信号的一个或多个频率分量。 以这种方式，患者可以通过提供由脑信号检测到的输入量来调节治疗递送，其中，该输入可能不需要与另一个装置的相互作用，从而消除了外部程序员调整治疗递送的需要。 示例治疗包括电刺激，药物递送和感觉线索的递送。

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