公开(公告)号：US09320686B2

公开(公告)日：2016-04-26

申请号：US14343300

申请日：2012-09-10

申请人： Norbert Moszner ,  Thomas Hirt ,  Kai Rist ,  Ulrich Salz ,  Christoph Weder ,  Gina Fiore ,  Christian Heinzmann ,  Volker Rheinberger

发明人： Norbert Moszner ,  Thomas Hirt ,  Kai Rist ,  Ulrich Salz ,  Christoph Weder ,  Gina Fiore ,  Christian Heinzmann ,  Volker Rheinberger

IPC分类号： A61K6/083 ,  A61C7/00 ,  A61K6/00 ,  C07D239/47 ,  C07F3/06 ,  C08F122/22

CPC分类号： A61K6/0835 ,  A61K6/0002 ,  A61K6/0023 ,  A61K6/083 ,  C07D239/47 ,  C07F3/06 ,  C08F122/22 ,  C08L33/00

摘要： The invention relates to a dental restorative material which comprises a thermolabile compound of Formula I: [(Z1)m-Q1-X)]k-T-[Y-Q2-(Z2)n]l  Formula I, in which T represents a thermolabile unit which contains at least one thermolabile group based on non-covalent interactions, Z1 and Z2 in each case independently represent a polymerizable group selected from vinyl groups, CH2═CR1—CO—O— and CH2═CR1—CO—NR2— or an adhesive group selected from —Si(OR)3, —COOH, —O—PO(OH)2, —PO(OH)2, —SO2OH and —SH, Q1 in each case independently is missing or represents an (m+1)-valent linear or branched aliphatic C1-C20 radical which can be interrupted by —O—, —S—, —CO—O—, —O—CO—, —CO—NR3—, —NR3—CO—, —O—CO—NR3—, —NR3—CO—O— or —NR3—CO—NR3—, Q2 in each case independently is missing or represents an (n+1)-valent linear or branched aliphatic C1-C20 radical which can be interrupted by —O—, —S—, —CO—O—, —O—CO—, —CO—NR3—, —NR3—CO—, —O—CO—NR3—, —NR3—CO—O— or —NR3—CO—NR3—, X and Y in each case independently are missing or represent —O—, —S—, CO—O—, —O—CO—, —CO—NR3— or —NR3—CO—, R, R1, R2 and R3 in each case independently represent H or a C1-C7 alkyl radical, k and l in each case independently are 0, 1, 2 or 3 and m and n in each case independently are 1, 2 or 3.

公开(公告)号：US08367748B2

公开(公告)日：2013-02-05

申请号：US11292578

申请日：2005-12-02

申请人： Norbert Moszner ,  Simone Klapdohr ,  Ulrich Salz ,  Jorg Zimmermann ,  Volker M. Rheinberger

发明人： Norbert Moszner ,  Simone Klapdohr ,  Ulrich Salz ,  Jorg Zimmermann ,  Volker M. Rheinberger

IPC分类号： A61K6/083 ,  C08K9/06 ,  A61C5/00

CPC分类号： A61K6/083 ,  A61K6/0017 ,  A61K6/0023 ,  A61K6/0073 ,  A61K6/093 ,  Y10T428/29 ,  C08L33/14 ,  C08L43/02 ,  C08L83/06

摘要： A filler which is surface-modified with a compound of the formula [(PG)-R1—Z]n—SP—[Y—R2-(AG)]m is particularly suitable for use in dental materials, for the preparation of adhesives, coatings and composites.

摘要翻译： 用[（PG）-R1-Z] n-SP- [Y-R2-（AG）] m的化合物进行表面改性的填料特别适用于牙科材料，用于制备粘合剂 ，涂料和复合材料。

公开(公告)号：US07851515B2

公开(公告)日：2010-12-14

申请号：US11212065

申请日：2005-08-25

申请人： Ulrich Salz ,  Angela Mucke ,  Jorg Zimmermann ,  Norbert Moszner ,  Frank Zeuner ,  Volker Rheinberger

发明人： Ulrich Salz ,  Angela Mucke ,  Jorg Zimmermann ,  Norbert Moszner ,  Frank Zeuner ,  Volker Rheinberger

IPC分类号： C07F9/06 ,  C07F9/113 ,  C07F9/143 ,  A61K6/083 ,  A61K6/08 ,  A61K6/00 ,  A61C5/00 ,  C08F20/58 ,  C08F220/54

CPC分类号： A61K6/083 ,  A61K6/0017 ,  A61K6/0023 ,  A61K6/0835 ,  C08L33/00

摘要： Dental composition containing (i) at least one acid (meth)acrylamide monomer which has two or more polymerizable groups, (ii) at least one acid monomer which has only one polymerizable group and (iii) at least one polymerization initiator.

摘要翻译： 含有（i）至少一种具有两个或多个可聚合基团的酸（甲基）丙烯酰胺单体，（ii）至少一种仅具有一个可聚合基团的酸单体和（iii）至少一种聚合引发剂）的牙科组合物。

公开(公告)号：US20060135719A1

公开(公告)日：2006-06-22

申请号：US11211938

申请日：2005-08-25

申请人： Norbert Moszner ,  Iris Lamparth ,  Frank Zeuner ,  Ulrich Salz ,  Angela Mucke ,  Jorg Zimmermann ,  Jorg Angermann ,  Volker Rheinberger

发明人： Norbert Moszner ,  Iris Lamparth ,  Frank Zeuner ,  Ulrich Salz ,  Angela Mucke ,  Jorg Zimmermann ,  Jorg Angermann ,  Volker Rheinberger

IPC分类号： C08F120/54

CPC分类号： A61K6/0017 ,  A61K6/0023 ,  A61K6/0029 ,  A61K6/083 ,  A61K6/09 ,  C08L33/26 ,  C08L33/04 ,  C08L75/04

摘要： Polymerizable dental material, characterized in that it contains at least one (meth)acrylamide phosphate of the following general formula (I): in which R1 is H or CH3; R2 is H or a C1-C4 alkyl radical or forms together with the nitrogen atom to which it is bonded and one or more atoms which belong to R3 or R3′ a heterocyclic ring; R3, R3′ independently of each other are a linear or branched aliphatic C1-C50 radical with a valency of m+n or p+n, an aromatic C6-C18 radical with a valency of m+n or p+n, or a cycloaliphatic, araliphatic or heterocyclic C3-C18 radical with a valency of m+n or p+n, wherein the carbon chains of the radical or radicals can be interrupted by O, S, CONR4, OCONH, or form together with one or more atoms which belong to R2 and the nitrogen atom, to which the R2 is bonded a heterocyclic ring, R3′ being H if p=0, and R4 being H, C1-C10 alkyl, C6-C12 aryl, C6-C10 aralkyl or a bicylic C4-C12 radical; n is 1, 2, 3 or 4 if p=0, and is 1 or 2 if p≠0; m is 1, 2, 3 or 4; p is 0, 1, 2, 3 or 4; x is 0 or S.

摘要翻译： 可聚合的牙科材料，其特征在于它含有至少一种下列通式（I）的（甲基）丙烯酰胺磷酸酯：其中R 1是H或CH 3; R 2是H或C 1 -C 4烷基，或与其键合的氮原子一起形成一个或多个 属于R 3或R 3'杂原子的杂原子; R 3，R 3，R 3'彼此独立地是直链或支链的脂族C 1 -C 50 - 基团 具有m + n或p + n的化合价，m + n或p + n的芳族C 6 -C 18 - 基团，或脂环族基团， 芳烷基或杂环C 3 -C 18 - 基团，其价态为m + n或p + n，其中基团或基团的碳链可以被O， S，CONR 4，OCONH，或与一个或多个属于R 2的原子和氮原子一起形成，R 2 O 2 >键合杂环，如果p = 0，则R 3'为H，R 4为H，C 1 -C 3 C 10 -C 12烷基，C 6 -C 12芳基，C 6 -C 10芳烷基或C 6 -C 12烷基 二元C 4 -C 12 - 基团; 如果p = 0，则n为1,2,3或4，如果p <0，则为1或2; m为1,2,3或4; p是0，1，2，3或4; x是0或S.

公开(公告)号：US06900251B2

公开(公告)日：2005-05-31

申请号：US10606142

申请日：2003-06-25

申请人： Norbert Moszner ,  Ulrich Salz ,  Frank Zeuner ,  Jörg Zimmermann ,  Volker Rheinberger ,  Jorg Angermann ,  Urs Karl Fischer

发明人： Norbert Moszner ,  Ulrich Salz ,  Frank Zeuner ,  Jörg Zimmermann ,  Volker Rheinberger ,  Jorg Angermann ,  Urs Karl Fischer

IPC分类号： A61C13/087 ,  A61K6/00 ,  A61K6/083 ,  C07F9/38 ,  C08F30/02 ,  C08F220/54 ,  C08F230/02 ,  C09J4/00 ,  C09J4/02 ,  C09J11/04 ,  C09J11/06 ,  A61K8/00 ,  C07F9/09 ,  C08F2/46

CPC分类号： A61K6/0023 ,  A61K6/083 ,  C07F9/3808 ,  C08F30/02 ,  C08L33/00 ,  C08L43/02 ,  C08L39/06

摘要： Acrylic ester phosphonic acids of general formula (I), stereoisomers thereof and mixtures of these, wherein n is 1 or 2, on the condition that for n=1 R1 has the meaning and for n=2 R1 has the meaning R2 is a C1 to C12 alkylene radical, C4-C8 cycloalkylene radical or C7 to C15 alkylene phenylene radical; R3 is hydrogen, a C1 to C5 alkyl radical or a C1 to C5 O-alkyl radical; and R4, R5, independently of each other, each stand for a C1 to C5 alkyl radical or a C1 to C5 O-alkyl radical.

摘要翻译： 在通式（I）的丙烯酸酯膦酸，其立体异构体和它们的混合物，其中n为1或2，条件是对于n = 1的R 1具有含义，n = 2 R 1具有R 2是C 1至C 12亚烷基的C 1至C 4亚烷基，C 4 C 1 -C 8亚环烷基或C 7至C 15亚烷基亚苯基; R 3是氢，C 1至C 5烷基或C 1至C 6烷基， 5 O - 烷基; 和R 4，R 5，R 5彼此独立地代表C 1至C 5烷基 自由基或C 1至C 5 - O-烷基。

公开(公告)号：US06353039B1

公开(公告)日：2002-03-05

申请号：US09209905

申请日：1998-12-11

申请人： Volker Rheinberger ,  Ulrich Salz ,  Wolfram Höland ,  André Rumphorst ,  Kurt Grabher ,  Urs Karl Fischer ,  Marcel Schweiger ,  Norbert Moszner

发明人： Volker Rheinberger ,  Ulrich Salz ,  Wolfram Höland ,  André Rumphorst ,  Kurt Grabher ,  Urs Karl Fischer ,  Marcel Schweiger ,  Norbert Moszner

IPC分类号： A61K6083

CPC分类号： A61K6/0276 ,  A61K6/083 ,  A61K6/09 ,  C08F2/44 ,  C08K3/40 ,  C08K9/08 ,  C08L33/00 ,  C08L75/16

摘要： A composite material is described which contains polymerizable monomers plus a special transparent glass having high release of calcium ions and fluorine ions and, because of this release property and in particular of its optical properties, can be used as a restoration material in dentistry.

摘要翻译： 描述了一种复合材料，其包含可聚合单体加上具有高释放的钙离子和氟离子的特殊透明玻璃，并且由于该释放性质，特别是其光学性质，可用作牙科中的修复材料。

公开(公告)号：US5703249A

公开(公告)日：1997-12-30

申请号：US548104

申请日：1995-10-25

申请人： Volker Rheinberger ,  Norbert Moszner ,  Ulrich Salz ,  Thomas Voelkel

发明人： Volker Rheinberger ,  Norbert Moszner ,  Ulrich Salz ,  Thomas Voelkel

IPC分类号： C07D321/06 ,  A61C13/00 ,  A61C13/23 ,  A61K6/00 ,  A61K6/08 ,  A61K6/087 ,  C07D321/10 ,  C07D493/04 ,  C07D493/10 ,  C07D493/20 ,  C08G63/00 ,  C08L67/00 ,  C07D317/44 ,  C07D317/72

CPC分类号： C07D493/04 ,  A61K6/0023 ,  A61K6/087 ,  C07D493/10

摘要： The present invention relates to novel bicycloaliphatic 2-methylene-1,3-dioxepanes, which are suitable as starting materials for the preparation of polymers and copolymers, preferably of composite and dental materials. The 2-methylene-1,3-dioxepanes according to the invention, which can undergo radical polymerisation with ring opening with only very little volume shrinkage, can be prepared in a simple manner, are easy to purify and to modify chemically, and are characterised by lack of odour and advantageous physical properties.

摘要翻译： 本发明涉及新的双环脂族2-亚甲基-1,3-二氧杂环庚烯，它们适合作为制备聚合物和共聚物的起始材料，优选为复合材料和牙科材料。 根据本发明的2-亚甲基-1,3-二氧杂环庚烯可以以简单的方式制备，其可以以仅具有非常小的体积收缩率的开环进行自由基聚合，易于化学纯化和修饰，并且被表征 缺乏气味和有利的物理特性。

公开(公告)号：US07622538B2

公开(公告)日：2009-11-24

申请号：US11211938

申请日：2005-08-25

申请人： Norbert Moszner ,  Iris Lamparth ,  Frank Zeuner ,  Ulrich Salz ,  Angela Mucke ,  Jorg Zimmermann ,  Jorg Angermann ,  Volker M. Rheinberger

发明人： Norbert Moszner ,  Iris Lamparth ,  Frank Zeuner ,  Ulrich Salz ,  Angela Mucke ,  Jorg Zimmermann ,  Jorg Angermann ,  Volker M. Rheinberger

IPC分类号： C08F20/58 ,  C08F20/60

CPC分类号： A61K6/0017 ,  A61K6/0023 ,  A61K6/0029 ,  A61K6/083 ,  A61K6/09 ,  C08L33/26 ,  C08L33/04 ,  C08L75/04

摘要： Polymerizable dental material, characterized in that it contains at least one (meth)acrylamide phosphate of the following general formula (I): in which R1 is H or CH3; R2 is H or a C1-C4 alkyl radical or forms together with the nitrogen atom to which it is bonded and one or more atoms which belong to R3 or R3′ a heterocyclic ring; R3, R3′ independently of each other are a linear or branched aliphatic C1-C50 radical with a valency of m+n or p+n, an aromatic C6-C18 radical with a valency of m+n or p+n, or a cycloaliphatic, araliphatic or heterocyclic C3-C18 radical with a valency of m+n or p+n, wherein the carbon chains of the radical or radicals can be interrupted by O, S, CONR4, OCONH, or form together with one or more atoms which belong to R2 and the nitrogen atom, to which the R2 is bonded a heterocyclic ring, R3′ being H if p=0, and R4 being H, C1-C10 alkyl, C6-C12 aryl, C6-10 aralkyl or a bicylic C4-C12 radial; n is 1, 2, 3 or 4 if p=0, and is 1 or 2 if p ≠0; m is 1, 2, 3 or 4; p is 0, 1, 2, 3 or 4; x is 0 or S.

摘要翻译： 可聚合牙科材料，其特征在于其含有至少一种下列通式（I）的（甲基）丙烯酰胺磷酸酯：其中R1是H或CH3; R2是H或C1-C4烷基或与其键合的氮原子一起形成一个或多个属于R3或R3'杂原子的原子; R 3，R 3'彼此独立地为具有m + n或p + n价的直链或支链脂族C 1 -C 50基团，价数为m + n或p + n的芳族C 6 -C 18基团或 脂环族，芳脂族或杂环C 3 -C 18基，其价态为m + n或p + n，其中基团或基团的碳链可被O，S，CONR 4，OCONH中断，或与一个或多个原子一起形成 属于R2和氮原子，R 2与杂环结合，如果p = 0，则R3'为H，R4为H，C1-C10烷基，C6-C12芳基，C6-10芳烷基或双 C4-C12径向; 如果p = 0，则n为1,2,3或4，如果p为0，则为1或2; m为1,2,3或4; p是0，1，2，3或4; x是0或S.

公开(公告)号：US06939489B2

公开(公告)日：2005-09-06

申请号：US10107526

申请日：2002-03-25

申请人： Norbert Moszner ,  Armin Burgath ,  Rolf Mulhaupt ,  Ulrich Salz ,  Volker Rheinberger ,  Rudiger Landers

发明人： Norbert Moszner ,  Armin Burgath ,  Rolf Mulhaupt ,  Ulrich Salz ,  Volker Rheinberger ,  Rudiger Landers

IPC分类号： A61C13/00 ,  A61C19/00 ,  A61K6/083 ,  B29C67/00 ,  A61C13/20 ,  B29C35/08 ,  B29C41/02 ,  B29C41/22

CPC分类号： A61K6/083 ,  A61C13/0004 ,  A61C13/0019 ,  A61C19/003 ,  B29C64/165 ,  B29L2031/7536 ,  B33Y80/00 ,  C08L33/00 ,  C08L25/04

摘要： A process for fabricating dental form pieces for dental restoration and replacement parts is provided and includes the step of applying a material, on a firm support or a fluid medium, by a three dimensional plotting technology in a layer by layer manner. The material has micro cords and/or micro drops which include at least one of a meltable, polymerizable, polycondensable, and polyaddable constituent element that is an unfilled monomer, a reinforced monomer, oligomer, polymer, or a ceramic element. The process also includes the step of hardening the applied material by cooling of the material, chemical reaction, polymerization with thermal handling, or polymerization by irradiation of the material with UV or visible light.

摘要翻译： 提供了一种用于制造用于牙科修复和更换部件的牙形片的方法，并且包括通过三维绘图技术逐层施加材料在坚固的支撑物或流体介质上的步骤。 所述材料具有微丝和/或微滴，其包括作为未填充单体，增强单体，低聚物，聚合物或陶瓷元素的可熔化，可聚合，可缩聚和可共聚的构成元素中的至少一种。 该方法还包括通过材料的冷却，化学反应，热处理聚合或用UV或可见光照射材料进行聚合来硬化所施加的材料的步骤。

公开(公告)号：US6031015A

公开(公告)日：2000-02-29

申请号：US682327

申请日：1996-07-17

申请人： Helmut Ritter ,  Georg Draheim ,  Norbert Moszner ,  Ulrich Salz ,  Volker Rheinberger

发明人： Helmut Ritter ,  Georg Draheim ,  Norbert Moszner ,  Ulrich Salz ,  Volker Rheinberger

IPC分类号： A61C13/23 ,  A61K6/083 ,  C07C69/54 ,  C07C69/92 ,  C07J9/00 ,  C08F2/50 ,  C08F20/26 ,  C08F20/30 ,  C08G63/181 ,  C08G63/19 ,  C09J4/00 ,  C09J4/02 ,  C09K19/20 ,  C09K19/36 ,  C08K9/06 ,  C08L67/07

CPC分类号： A61K6/083 ,  C07C69/92 ,  C09K19/2007 ,  C09K19/36 ,  C09K2019/0448 ,  Y10S522/908

摘要： A dental material based on polymerizable monomers is described which contains at least one polymerizable monomer which has liquid crystalline properties. Compared with traditional materials, the dental material displays a lower decrease in volume upon polymerization and, because of its low viscosity, higher filler contents can be achieved.

摘要翻译： 描述了基于可聚合单体的牙科材料，其含有至少一种具有液晶性质的可聚合单体。 与传统材料相比，牙科材料在聚合时体积减小，粘度低，可以实现更高的填料含量。