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    VENTILATORY ASSISTANCE FOR TREATMENT OF CARDIAC FAILURE AND CHEYNE-STOKES BREATHING
    15.
    发明申请
    VENTILATORY ASSISTANCE FOR TREATMENT OF CARDIAC FAILURE AND CHEYNE-STOKES BREATHING 审中-公开
    治疗心脏病失败和呼吸道呼吸的通气辅助

    公开(公告)号：US20150013679A1

    公开(公告)日：2015-01-15

    申请号：US14476953

    申请日：2014-09-04

    Applicant: ResMed Limited

    Inventor： Michael Berthon-Jones

    IPC: A61M16/00

    CPC classification number: A61M16/0003 ,  A61M16/00 ,  A61M16/0051 ,  A61M16/0057 ,  A61M16/0069 ,  A61M16/024 ,  A61M16/0858 ,  A61M2016/0039 ,  A61M2205/3303 ,  A61M2230/42

    Abstract: Method and apparatus for the treatment of cardiac failure, Cheyne Stokes breathing or central sleep apnea are disclosed. A subject is provided with ventilatory support. Respiratory airflow is determined. From the respiratory airflow are derived a measure of instantaneous ventilation (for example half the absolute value of the respiratory airflow) and a measure of longterm average ventilation. A target ventilation is taken as 95% of the longterm average ventilation. The instantaneous ventilation is fed as the input signal to a clipped integral controller, with the target ventilation as the reference signal. The output of the controller determines the degree of ventilatory support. A third measure of ventilation, for example instantaneous ventilation low pass filtered with a time constant of 5 seconds, is calculated. Ventilatory support is in phase with the subject's respiratory airflow to the fuzzy extent that this ventilation is above target, and at a preset rate conversely.

    Abstract translation: 公开了用于治疗心力衰竭，Cheyne Stokes呼吸或中枢性睡眠呼吸暂停的方法和装置。 受试者提供通气支持。 确定呼吸气流。 从呼吸气流得出瞬时通气量（例如呼吸气流的绝对值的一半）和长期平均通气量的测量。 目标通气量为长期平均通气量的95％。 瞬时通风作为输入信号输入到夹紧积分控制器，目标通风作为参考信号。 控制器的输出决定通气支持的程度。 计算第三种通气量，例如用5秒的时间常数过滤的瞬时通风低通量。 通气支持与受试者的呼吸气流同步，模糊程度是这种通气高于目标，并且以相反的预设速率。

    Administration of CPAP treatment pressure in presence of apnea
    18.
    发明授权
    Administration of CPAP treatment pressure in presence of apnea 有权
    呼吸暂停治疗CPAP治疗压力

    公开(公告)号：US09526855B2

    公开(公告)日：2016-12-27

    申请号：US14187919

    申请日：2014-02-24

    Applicant: ResMed Limited

    Inventor： Michael Berthon-Jones ,  Steven Paul Farrugia

    IPC: A61M16/00 ,  A61M16/06 ,  A61B5/0205 ,  A61B5/00 ,  A61M16/08

    CPC classification number: A61M16/0069 ,  A61B5/0205 ,  A61B5/4818 ,  A61B5/4836 ,  A61M16/00 ,  A61M16/0003 ,  A61M16/0051 ,  A61M16/024 ,  A61M16/06 ,  A61M16/0875 ,  A61M2016/0036

    Abstract: CPAP treatment apparatus is disclosed having a controllable flow generator (34, 38, 40) operable to produce breathable gas at a treatment pressure elevated above atmosphere to a patient by a delivery tube (32) coupled to a mask (30) having connection with a patient's airway. A sensor (44, 50, 56, 58) generates a signal representative of patient respiratory flow, that is provided to a controller (54, 62, 64). The controller (54, 62, 64) is operable to determine the occurrence of an apnea from a reduction in respiratory airflow below a threshold, and if an apnea has occurred, to determine the duration of the apnea and to cause the flow generator (34, 38) to increase the treatment pressure. In one preferred form the increase in pressure is zero if the treatment pressure before the apnea exceeds a pressure threshold. Below the pressure threshold the increase in pressure is an increasing of the duration of the apnea multiplied by the between the pressure threshold and the current function difference treatment pressure.

    Abstract translation: 公开了一种CPAP治疗装置，其具有可操作的流量发生器（34,38,40），其可操作以通过耦合到具有与一个或多个连接器的连接的掩模（30）的输送管（32）在处于高于大气的处理压力下向患者产生可呼吸气体 病人的气道。 传感器（44,50,56,58）产生代表患者呼吸流量的信号，其提供给控制器（54,62,64）。 控制器（54,62,64）可操作以从呼吸气流减少到阈值以下来确定呼吸暂停的发生，并且如果发生呼吸暂停，则确定呼吸暂停的持续时间并使流量发生器（34 ，38）以增加治疗压力。 在一个优选形式中，如果呼吸暂停之前的治疗压力超过压力阈值，则压力增加为零。 在压力阈值以下，压力的增加是呼吸暂停的持续时间乘以压力阈值与当前功能差异治疗压力之间的增加。

    Ventilatory assistance for treatment of cardiac failure and cheyne-stokes breathing
    19.
    发明授权
    Ventilatory assistance for treatment of cardiac failure and cheyne-stokes breathing 有权
    呼吸辅助治疗心力衰竭和犬蹄呼吸

    公开(公告)号：US08857430B2

    公开(公告)日：2014-10-14

    申请号：US13962493

    申请日：2013-08-08

    Applicant: ResMed Limited

    Inventor： Michael Berthon-Jones

    IPC: A61M11/00 ,  A61M16/00

    CPC classification number: A61M16/0003 ,  A61M16/00 ,  A61M16/0051 ,  A61M16/0057 ,  A61M16/0069 ,  A61M16/024 ,  A61M16/0858 ,  A61M2016/0039 ,  A61M2205/3303 ,  A61M2230/42

    Abstract: Method and apparatus for the treatment of cardiac failure, Cheyne Stokes breathing or central sleep apnea are disclosed. A subject is provided with ventilatory support Respiratory airflow is determined. From the respiratory airflow are derived a measure of instantaneous ventilation and a measure of longterm average ventilation. A target ventilation is taken as 95% of the longterm average ventilation. The instantaneous ventilation is fed as the input signal to a clipped integral controller, with the target ventilation as the reference signal. The output of the controller determines the degree of ventilatory support. A third measure of ventilation, for example instantaneous ventilation low pass filtered with a time constant of 5 seconds, is calculated. Ventilatory support is in phase with the subject's respiratory airflow to the fuzzy extent that this ventilation is above target, and at a preset rate conversely.

    Abstract translation: 公开了用于治疗心力衰竭，Cheyne Stokes呼吸或中枢性睡眠呼吸暂停的方法和装置。 受试者提供通气支持确定呼吸气流。 从呼吸气流得出瞬时通气的度量和长期平均通气量的测量。 目标通气量为长期平均通气量的95％。 瞬时通风作为输入信号输入到夹紧积分控制器，目标通风作为参考信号。 控制器的输出决定通气支持的程度。 计算第三种通气量，例如用5秒的时间常数过滤的瞬时通风低通量。 通气支持与受试者的呼吸气流同步，模糊程度是这种通气高于目标，并且以相反的预设速率。

    ADMINISTRATION OF CPAP TREATMENT PRESSURE IN PRESENCE OF APNEA
    20.
    发明申请
    ADMINISTRATION OF CPAP TREATMENT PRESSURE IN PRESENCE OF APNEA 有权
    APNEA存在的CPAP治疗压力的管理

    公开(公告)号：US20140166014A1

    公开(公告)日：2014-06-19

    申请号：US14187919

    申请日：2014-02-24

    Applicant: ResMed Limited

    Inventor： Michael Berthon-Jones ,  Steven Paul Farrugia

    IPC: A61M16/00 ,  A61M16/08 ,  A61M16/06 ,  A61B5/00 ,  A61B5/0205

    CPC classification number: A61M16/0069 ,  A61B5/0205 ,  A61B5/4818 ,  A61B5/4836 ,  A61M16/00 ,  A61M16/0003 ,  A61M16/0051 ,  A61M16/024 ,  A61M16/06 ,  A61M16/0875 ,  A61M2016/0036

    Abstract: CPAP treatment apparatus is disclosed having a controllable flow generator (34, 38, 40) operable to produce breathable gas at a treatment pressure elevated above atmosphere to a patient by a delivery tube (32) coupled to a mask (30) having connection with a patient's airway. A sensor (44, 50, 56, 58) generates a signal representative of patient respiratory flow, that is provided to a controller (54, 62, 64). The controller (54, pressure. In one preferred form the increase in pressure is zero if the treatment pressure before the apnea exceeds a pressure threshold. Below the pressure threshold the increase in pressure is an increasing function of the duration of the apnea multiplied by the difference between the pressure threshold and the current treatment pressure.

    Abstract translation: 公开了一种CPAP治疗装置，其具有可操作的流量发生器（34,38,40），其可操作以通过耦合到具有与一个或多个连接器的连接的掩模（30）的输送管（32）在处于高于大气的处理压力下向患者产生可呼吸气体 病人的气道。 传感器（44,50,56,58）产生代表患者呼吸流量的信号，其提供给控制器（54,62,64）。 控制器（54，压力）在一个优选形式中，如果呼吸暂停之前的治疗压力超过压力阈值，则压力的增加为零。低于压力阈值时，压力的增加是呼吸暂停持续时间的乘积乘以 压力阈值与当前治疗压力之间的差异。

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