公开(公告)号：US08128568B2

公开(公告)日：2012-03-06

申请号：US12238091

申请日：2008-09-25

申请人： Shih-Ping Wang ,  Douglas G. Summers ,  Jiayu Chen ,  Tor C. Anderson

发明人： Shih-Ping Wang ,  Douglas G. Summers ,  Jiayu Chen ,  Tor C. Anderson

IPC分类号： A61B8/00

CPC分类号： A61B10/0233 ,  A61B8/4427 ,  A61B8/4455 ,  A61B8/4461 ,  A61B8/483 ,  A61B90/11 ,  A61B2090/378

摘要： An apparatus and related methods for ultrasonically scanning a tissue volume are described, the apparatus being particularly advantageous in the context of freehand ultrasound assisted biopsy of the breast although readily applied to non-biopsy contexts and other body parts. The apparatus comprises a casing configured and dimensioned for single-handed manipulation relative to a surface of the tissue, and a texturably couplant-porous material sheet extending across an opening of the casing. The texturably couplant-porous material sheet has an outer side and an inner side relative to the casing, the outer side for compressively contacting the tissue surface. The apparatus further comprises an ultrasound transducer positioned against the inner side of the texturably couplant-porous material sheet and being mechanically translatable thereacross for volumetrically scanning the tissue volume therethrough.

摘要翻译： 描述了用于超声扫描组织体积的装置和相关方法，该装置在乳房的手写超声辅助活检的上下文中特别有利，尽管容易地应用于非活检上下文和其他身体部位。 该装置包括一个外壳，其被配置和尺寸设计成相对于该组织的表面进行单手操作，以及一个横跨该外壳的开口延伸的可变形的耦合剂 - 多孔材料片。 可变形的联合多孔材料片具有相对于外壳的外侧和内侧，用于压缩地接触组织表面的外侧。 该装置还包括一个超声波换能器，该超声波换能器抵靠着可柔软的耦合剂 - 多孔材料片的内侧，并可在其上机械平移，用于体积扫描组织体积。

公开(公告)号：US20110098566A1

公开(公告)日：2011-04-28

申请号：US12890374

申请日：2010-09-24

申请人： Wei ZHANG ,  Shih-Ping Wang ,  Jiayu Chen ,  Zengpin Yu ,  Tommy Earl Cupples ,  Thomas P. Neff ,  Michael E. Reed

发明人： Wei ZHANG ,  Shih-Ping Wang ,  Jiayu Chen ,  Zengpin Yu ,  Tommy Earl Cupples ,  Thomas P. Neff ,  Michael E. Reed

IPC分类号： A61B8/14 ,  G06T15/20

CPC分类号： A61B8/5238 ,  A61B6/463 ,  A61B6/502 ,  A61B6/5247 ,  A61B6/563 ,  A61B8/0825 ,  A61B8/13 ,  A61B8/406 ,  A61B8/4281 ,  A61B8/4405 ,  A61B8/462 ,  A61B8/463 ,  A61B8/465 ,  A61B8/466 ,  A61B8/467 ,  A61B8/565

摘要： Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.

摘要翻译： 描述了在交互式用户界面上显示乳房超声信息，用户界面在辅助超声乳腺X线照相术环境和/或仅超声乳腺X线照相术环境中有用。 通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。 描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。 在一个优选实施例中，乳头标记被显示为表示其上的乳头位置的投影的冠状厚片图像。 还显示方便的胸部图标，包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。 优选地，乳房图标被配置为至少大致类似于时钟面，时钟面的中心表示乳头标记位置。 还描述了厚片图像内和书签中心和CAD标记为中心的导航。

公开(公告)号：US20080269613A1

公开(公告)日：2008-10-30

申请号：US11587078

申请日：2005-04-26

申请人： Douglas G. Summers ,  Shih-Ping Wang ,  Jiayu Chen ,  Tor C. Anderson

发明人： Douglas G. Summers ,  Shih-Ping Wang ,  Jiayu Chen ,  Tor C. Anderson

IPC分类号： A61B8/00

CPC分类号： A61B8/0825 ,  A61B8/406 ,  A61B8/4218 ,  A61B8/4281 ,  A61B8/4405 ,  A61B8/4455 ,  A61B8/4472 ,  A61B8/461 ,  A61B8/467 ,  A61B8/483

摘要： Versatile ultrasound scanning of a breast is described using an apparatus (1202) including a hand-manipulable compression/scanning assembly (1208). The compression/scanning assembly (1208) comprises an ultrasound transducer (1304) and a compressive member comprising an at least partially conformable membrane (1218) in a substantially taut state, the membrane (1218) having a first surface compressing the breast in a generally chestward direction and a second surface opposite the first surface. The compression/scanning assembly (1208) further comprises a transducer translation mechanism coupled to the ultrasound transducer (1304) and configured to sweep the ultrasound transducer across the second surface of the membrane to scan the breast while compressed in the generally chestward direction. Systemized and/or standardized ultrasonic scanning of a breast based on hand-manipulable scanners (1208, 1508) having substantially planar scanning surfaces is also described.

摘要翻译： 使用包括可手动操纵的压缩/扫描组件（1208）的装置（1202）来描述乳房的多功能超声扫描。 压缩/扫描组件（1208）包括超声换能器（1304）和包括基本拉紧状态的至少部分适形膜（1218）的压缩构件，所述膜（1218）具有第一表面，以一般地压缩乳房 胸前方向和与第一表面相对的第二表面。 压缩/扫描组件（1208）还包括耦合到超声换能器（1304）的换能器平移机构，并被配置成扫过超声波换能器穿过膜的第二表面，以在大致向胸部方向压缩的同时扫描乳房。 还描述了基于具有基本上平面扫描表面的可手动操纵的扫描仪（1208,1508）的乳房的系统化和/或标准化的超声波扫描。

公开(公告)号：US20080177163A1

公开(公告)日：2008-07-24

申请号：US12017969

申请日：2008-01-22

申请人： Shih-Ping Wang ,  Xuefeng Cheng ,  Zengpin Yu

发明人： Shih-Ping Wang ,  Xuefeng Cheng ,  Zengpin Yu

IPC分类号： A61B5/1455

CPC分类号： A61B5/0073 ,  A61B5/14553 ,  A61B5/4064 ,  A61B5/6814 ,  A61B2562/0233 ,  A61B2562/046

摘要： Methods, systems, and related computer program products for non-invasive monitoring of a biological volume, such as a human brain, are described. In one preferred embodiment, each of a plurality of optical sources emits optical radiation into the biological volume each of a plurality of optical detectors detects optical radiation impinging thereupon from the biological volume. The optical measurements are processed to compute a requisite property value associated with each source-detector pair. For each source-detector pair, a volumetric basis region corresponding thereto is weighted by the requisite property value, the volumetric basis region being predetermined and representative of an estimated subvolume of the biological volume encountered by optical radiation emitted from that source and propagating to that detector. The weighted volumetric basis regions are accumulated into a volumetric cumulative array, and a display output is generated based at least in part on the volumetric cumulative array.

摘要翻译： 描述了用于非侵入性监测生物体积的方法，系统和相关的计算机程序产品，例如人类大脑。 在一个优选实施例中，多个光源中的每一个将光辐射发射到生物体积中，多个光学检测器中的每一个检测器从生物体积检测入射的光辐射。 处理光学测量以计算与每个源 - 检测器对相关联的必要属性值。 对于每个源 - 检测器对，与其对应的体积基础区域由所需的属性值加权，体积基础区域是预定的，并且代表从该源发射并传播到该检测器的光辐射遇到的生物体积的估计子体积 。 加权体积基础区域被累积到体积累积阵列中，并且至少部分地基于体积累积阵列生成显示输出。

公开(公告)号：US20080130833A1

公开(公告)日：2008-06-05

申请号：US12012257

申请日：2008-01-31

申请人： Shih-Ping Wang

发明人： Shih-Ping Wang

IPC分类号： H05G1/64

CPC分类号： A61B6/463 ,  A61B5/055 ,  A61B6/00 ,  A61B6/032 ,  A61B6/502 ,  A61B6/5205 ,  G06F19/321 ,  G06T19/00 ,  G06T2210/41 ,  G06T2219/028 ,  G16H50/20

摘要： A method and associated systems for processing and displaying three-dimensional medical imaging data of a subject anatomical volume is described in which a plurality of thick-slice images is computed and displayed, each thick-slice image corresponding to a thick-slice or slab-like subvolume of the anatomical volume substantially parallel to a standard x-ray view plane for that anatomical volume. The thick-slice or slab-like subvolumes have a thickness generally related to a lesion size to be detected and/or examined. The described thick-slice processing and display is generally applicable for any anatomical volume (e.g. chest, head, abdomen, breast, etc.) having associated standard x-ray views (e.g., PA, lateral, CC, MLO, etc.) that is also amenable to one or more three-dimensional imaging modalities (e.g., MRI, CT, SPECT, PET, ultrasound, etc.). According to one preferred embodiment in which the particular three-dimensional imaging modality is CT imaging, thick-slice processing and display is used to facilitate reduced screening radiation dosage.

摘要翻译： 描述了一种用于处理和显示主题解剖体积的三维医学成像数据的方法和相关系统，其中计算和显示多个厚片图像，每个厚片图像对应于厚片或板状图像， 解剖体积的像体积基本上平行于该解剖体积的标准X射线视野平面。 厚切片或板状子体积具有通常与待检测和/或检查的病变大小有关的厚度。 所描述的厚切片处理和显示通常适用于具有相关联的标准x射线视图（例如，PA，横向，CC，MLO等）的任何解剖体积（例如胸部，头部，腹部，乳房等）， 也适用于一种或多种三维成像模式（例如MRI，CT，SPECT，PET，超声等）。 根据其中特定三维成像模式是CT成像的一个优选实施例，使用厚切片处理和显示来促进减少的筛选辐射剂量。

公开(公告)号：US07018333B2

公开(公告)日：2006-03-28

申请号：US10466568

申请日：2001-11-20

申请人： Shih-Ping Wang ,  Tommy Earl Cupples ,  Xiangyong Cheng

发明人： Shih-Ping Wang ,  Tommy Earl Cupples ,  Xiangyong Cheng

IPC分类号： A61B8/00

CPC分类号： G01S15/8993 ,  A61B8/0833 ,  A61B10/0096 ,  A61B2090/378 ,  G01N29/0609 ,  G01N29/223 ,  G01N29/28 ,  G01N2291/02466 ,  G01S7/52017

摘要： An apparatus and related methods for ultrasound-assisted surgical removal of a tumor or other biological object from a patient, the tumor requiring complete removal such that no portion thereof remains inside the patient, is described. According to a preferred embodiment, a specimen containing the tumor is extracted from the patient and suspended in a container holding an acoustically conductive fluid. An ultrasound probe is brought into acoustic communication with the fluid and scans the specimen, preferably at an acoustic power setting higher than a maximum ultrasonic power permitted on live human tissue. Resulting two-dimensional and/or three-dimensional ultrasound images of the specimen, which have a higher quality due to the increased acoustic power of the scan, are viewed on an output display for examining whether any portion of the tumor comes into contact with a surface of the specimen. Preferably, the ultrasound images are segmented and processed by the ultrasound system in a manner that further assists in the determination of whether the specimen contains the entire tumor.

摘要翻译： 描述了用于从患者超声辅助手术切除肿瘤或其他生物体的装置和相关方法，所述肿瘤需要完全去除，使得其中没有部分残留在患者体内。 根据优选实施方案，从患者中提取含有肿瘤的样本，并将其悬浮在容纳声导电液体的容器中。 将超声波探头与流体进行声学连通，并扫描样本，优选地在高于活体组织允许的最大超声功率的声功率设定。 在输出显示器上观察由于扫描增加的声功率而具有较高质量的样本的所得到的二维和/或三维超声图像，用于检查肿瘤的任何部分是否与 试样表面。 优选地，超声图像被分段和超声系统处理，以进一步有助于确定样本是否包含整个肿瘤的方式。

公开(公告)号：US06477262B2

公开(公告)日：2002-11-05

申请号：US09891676

申请日：2001-06-26

申请人： Shih-Ping Wang

发明人： Shih-Ping Wang

IPC分类号： G06K900

CPC分类号： G06T5/50 ,  G06F19/00 ,  G06F19/321 ,  G06K2209/053 ,  G06T7/0012 ,  G06T2207/10116 ,  G06T2207/30068 ,  G16H15/00 ,  G16H40/63 ,  G16H50/20 ,  H05G1/60

摘要： A computer-aided diagnostic (CAD) method and system provide image annotation information that can include an assessment of the probability, likelihood or predictive value of the CAD-detected suspected abnormalities as an additional aid to the radiologist. More specifically, probability values, in numerical form and/or analog form, are added to the locational markers of the CAD-detected suspected abnormalities. The task of a physician using a CAD system is believed to be made easier by displaying two different markers representing different probability thresholds. An additional threshold can be used to display “extra view markers” as an additional aid or guide to the radiologic technician to take extra views of a patient before the patient is released or discharged. A control device is added to allow the user to select and vary the probability threshold for the display of locational markers.

公开(公告)号：US4953189A

公开(公告)日：1990-08-28

申请号：US256846

申请日：1988-10-12

申请人： Shih-Ping Wang

发明人： Shih-Ping Wang

IPC分类号： A61B6/03 ,  G21K1/04 ,  H05G1/36 ,  H05G1/44 ,  H05G1/60

CPC分类号： A61B6/032 ,  A61B6/06 ,  A61B6/4035 ,  A61B6/544 ,  G21K1/04 ,  G21K1/046 ,  H05G1/36 ,  H05G1/44 ,  H05G1/60

摘要： A method and device for producing flux equalized x-ray images for medical radiography through the use of a scanning fan shaped x-ray beam and a feedback control system which regulates the beam intensity at a multiple number of points along the fan beam to compensate for the x-ray attenuation variations of the patient.

摘要翻译： 一种用于通过使用扫描扇形X射线束产生用于医学放射照相的磁通均衡x射线图像的方法和装置，以及反馈控制系统，其调节沿着扇形束的多个点处的光束强度以补偿 患者的x射线衰减变化。

公开(公告)号：US4255666A

公开(公告)日：1981-03-10

申请号：US18127

申请日：1979-03-07

申请人： Shih-Ping Wang ,  Charles D. Robbins

发明人： Shih-Ping Wang ,  Charles D. Robbins

IPC分类号： H01J29/38 ,  H01J29/92 ,  H01J31/50 ,  G01T1/00 ,  G01T1/20

CPC分类号： H01J29/385 ,  H01J29/92 ,  H01J31/505

摘要： A panel shaped, proximity type, multi-stage x-ray image intensifier tube for medical x-ray diagnostic use having all linear components and yet a high brightness gain, the tube being comprised of a rugged metallic tube envelope, an inwardly concave, metallic input window, a full size output display screen, a planar, activated alkali-halide scintillator photocathode screen, a fiberoptic plate between the scintillator-photocathode screen and the output display screen, the plate having an intermediate display screen on one flat side facing the scintillator-photocathode screen and a second photocathode on the otherside, which faces the output display screen, and with the scintillator-photocathode screen and the fiberoptic plate being suspended on insulators within the envelope and in between the input window and the output screen. Separate, high, negative electrostatic potentials are applied between the scintillator-photocathode screen and the intermediate display screen and between the second photocathode and the output display screen. The tube can be used in a direct view, photofluorographic mode, in a radiographic camera system and with a remote view T.V. system.

摘要翻译： 一种用于医疗x射线诊断用途的面板形，接近型，多级X射线图像增强管，具有所有线性分量并具有高亮度增益，该管由坚固的金属管外壳，向内凹的金属 输入窗口，全尺寸输出显示屏幕，平面激活的碱卤化物闪烁体光电阴极屏幕，闪烁体 - 光电阴极屏幕和输出显示屏幕之间的光纤板，该板在面向闪烁体的一个平坦侧上具有中间显示屏 在另一侧面对输出显示屏，并且闪烁体 - 光电阴极屏幕和光纤板悬挂在封套内的绝缘体之间并且在输入窗口和输出屏幕之间的第二光电阴极。 在闪烁体 - 光电阴极屏幕和中间显示屏幕之间以及第二光电阴极和输出显示屏幕之间施加独立的高负的静电电位。 管可以直接使用，光学照相模式，放射照相机系统和远程视图T.V.系统。

公开(公告)号：US11020086B2

公开(公告)日：2021-06-01

申请号：US15975544

申请日：2018-05-09

申请人： Shih-Ping Wang

发明人： Shih-Ping Wang

IPC分类号： A61B8/08 ,  A61B8/00 ,  A61B8/14

摘要： A method and apparatus for acquisition of volumetric breast images for screening and/or diagnosing breast cancers using a rotary scanning template and transducer.