摘要:
A combinatorial test device is configurable to contemporaneously test one or more sensors of output devices free from user intervention. A device under test such as a user device is placed in a test fixture of the combinatorial test device. Under the control and monitoring of a test controller testing takes place. The testing may be performed for quality assurance after assembly or repair, or to determine the reliability of the device such as by testing the device until a particular life cycle value is reached or a component in the device fails.
摘要:
Melanocortin receptor-specific cyclic peptides of the formula where R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and z are as defined in the specification, compositions and formulations including the peptides of the foregoing formula, and methods of preventing, ameliorating or treating melanocortin receptor-mediated diseases, indications, conditions and syndromes.
摘要:
A melanocortin receptor agonist cyclic peptide of the formula where R, x and y are as defined in the specification, compositions and formulations including the peptide of the foregoing formula, and methods of preventing, ameliorating or treating melanocortin receptor-mediated diseases, indications, conditions and syndromes, including sexual dysfunction such as male erectile dysfunction and female sexual dysfunction.
摘要:
Embodiments of the present disclosure provide for analyte sensors, methods for producing and using the analyte sensors, methods of detecting and/or measuring analyte activity, methods for characterizing analyte cellular activity, methods of detecting pH change in a system, method of controlling the concentration of an analyte in a system, fusion proteins, polynucleotides, and vectors corresponding to the analyte sensors, kits, and the like.
摘要:
Disclosed herein are methods relating to inhibiting or reducing proliferation of a cancer cell, for treating cancer in a subject in need of treatment, predicting the risk of progression of cancer to a more aggressive cancer, and screening for cancer in a subject, that comprise detecting and/or decreasing the levels of SUMO conjugated proteins and detecting and/or interfering with SUMO conjugation.
摘要:
Melanocortin receptor-specific linear peptides of the formula where R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are as defined in the specification, compositions and formulations including peptides of the foregoing formula or salts thereof, and pharmaceutical compositions for preventing, ameliorating or treating melanocortin-1 receptor-mediated or responsive diseases, indications, conditions and syndromes.
摘要:
A chip-scale ion-trap mass spectrometer driven by a monolithic photodiode array and a method of fabricating the same. A high-voltage photovoltaic source is located in proximity to the ion-trap mass spectrometer structure. The high-voltage photovoltaic source includes monolithically fabricated and serially connected photodiodes. An external light source illuminates the photodiodes to generate a high voltage across the photodiode array. An RF voltage modulation is attained by modulating the light source at a desired RF frequency. The high-voltage photodiode array may be monolithically fabricated in association with the ion-trap mass spectrometer. The photodiode array requires a small area compared to the ion-trap mass spectrometer size as the spectrometer typically possess a very small capacitance and a low power consumption.
摘要:
The present disclosure is related to thermostable Y-family polymerases, in particular several novel Y-family polymerases and chimeras made therefrom, as well as methods of identifying other Y-family polymerases, methods of generating other chimeric Y-family polymerases, methods of amplifying ancient or damaged DNA, and methods of incorporating fluorescent or modified nucleotides into a DNA molecule.
摘要:
A chip-scale ion-trap mass spectrometer driven by a monolithic photodiode array and a method of fabricating the same. A high-voltage photovoltaic source is located in proximity to the ion-trap mass spectrometer structure. The high-voltage photovoltaic source includes monolithically fabricated and serially connected photodiodes. An external light source illuminates the photodiodes to generate a high voltage across the photodiode array. An RF voltage modulation is attained by modulating the light source at a desired RF frequency. The high-voltage photodiode array may be monolithically fabricated in association with the ion-trap mass spectrometer. The photodiode array requires a small area compared to the ion-trap mass spectrometer size as the spectrometer typically possess a very small capacitance and a low power consumption.
摘要:
An apparatus includes a plurality of islands each carrying multiple cantilevers. The apparatus also includes a fluidic network having a plurality of channels separating the islands. The channels are configured to provide fluid to the islands, and the fluid at least partially fills spaces between the cantilevers and the islands. Heat from the islands vaporizes the fluid filling the spaces between the cantilevers and the islands to transfer the heat away from the islands while driving the cantilevers into oscillation. The apparatus may also include a casing configured to surround the islands and the fluidic network to create a vapor chamber, where the vapor chamber is configured to retain the vaporized fluid. The islands and the fluidic network could be formed in a single substrate, or the islands could be separate and attached together by a binder located within the channels of the fluidic network.