公开(公告)号：US5183300A

公开(公告)日：1993-02-02

申请号：US826465

申请日：1992-01-27

申请人： Andreas Bonne ,  Klaus Claar ,  Jurgen Schrader

发明人： Andreas Bonne ,  Klaus Claar ,  Jurgen Schrader

IPC分类号： E05B85/24

CPC分类号： E05B85/243 ,  Y10S292/05 ,  Y10T292/1047

摘要： A fastening arrangement for a movable part especially a folding top or a roof of a motor vehicle. The arrangement includes a rotary latch which serves for securing a fastening pin of the movable part and is rotatable by means of an actuating device for a blocking and release of the fastening pin which can be retained by means of a detent pawl. In the locked position of the fastening, the detent pawl rests in an undercut principal notch of the rotary latch. High frictional forces and disturbing noises therefore are avoided during the unlocking operation. The rotary latch is rotatable through a specific angle oppositely to the blocking direction of the detent pawl by means of a control device activatable by the actuating device.

摘要翻译： 用于可移动部件，特别是机动车辆的折叠顶部或屋顶的紧固装置。 该装置包括旋转闩锁，其用于固定可移动部件的紧固销，并且可通过致动装置旋转，以阻止和释放紧固销，该销可借助于止动爪保持。 在紧固的锁定位置，止动爪位于旋转闩锁的底切主要凹口中。 因此，在解锁操作期间避免了高摩擦力和干扰噪声。 旋转闩锁可通过由致动装置激活的控制装置旋转穿过与止动爪的阻挡方向相反的特定角度。

公开(公告)号：US4936626A

公开(公告)日：1990-06-26

申请号：US330900

申请日：1989-03-31

申请人： Gunter Gmeiner ,  Christian Grabner ,  Klaus Claar ,  Jurgen Schrader ,  Hermann Moeller

发明人： Gunter Gmeiner ,  Christian Grabner ,  Klaus Claar ,  Jurgen Schrader ,  Hermann Moeller

IPC分类号： B60J7/12

CPC分类号： B60J7/1273

摘要： For swivel-assistance to a roof-skin holding bow forming the lower end of a folding canopy, lateral limbs of the holding bow being affixed to associated canopy struts of a main hoop, there is provided a rod element, the length of which can be altered, which is articulated at both ends and is arranged in the side wall region of the folding canopy. Since on end of the rod element is connected to the facing lateral limb of the roof-skin holding bow and the second end of the rod element is connected in articulated fashion to the associated canopy strut, the rod element can be arranged in space-saving manner in the side board.

摘要翻译： 为了对构成折叠冠的下端的屋顶皮肤保持弓的旋转辅助，保持弓的侧肢被固定到主箍的相关的冠层支柱上，提供了一个杆元件，其长度可以是 改变，其在两端铰接并布置在折叠冠层的侧壁区域中。 由于杆元件的端部连接到屋顶皮肤保持弓的相对的侧肢，并且杆元件的第二端以铰接的方式连接到相关联的顶盖支柱，所以杆元件可以节省空间 方式在侧板。

公开(公告)号：US5253575A

公开(公告)日：1993-10-19

申请号：US923447

申请日：1992-08-03

申请人： Klaus-Peter Claar ,  Frank van de Poel ,  Kurt Schaible ,  Jurgen Schrader ,  Holger Seel

发明人： Klaus-Peter Claar ,  Frank van de Poel ,  Kurt Schaible ,  Jurgen Schrader ,  Holger Seel

IPC分类号： B60J7/12 ,  B60J7/20 ,  E05B51/02 ,  E05F15/50 ,  F15B15/26

CPC分类号： B60J7/202 ,  E05B51/02 ,  E05F15/50 ,  E05Y2900/508 ,  E05Y2900/548

摘要： A drive system for a lid or a flap of a convertible car body in which the control effort for the drive system is reduced by configuring the working cylinder as a control valve which releases the lid or the like after unlocking of the lock for lifting by the lifting cylinder, and is connected between the control device and the lifting cylinder.

摘要翻译： 一种用于可转换车体的盖子或挡板的驱动系统，其中通过将工作缸构造为控制阀来减小驱动系统的控制力，所述控制阀在解锁锁之后释放盖子等 提升缸，并连接在控制装置和提升缸之间。

公开(公告)号：US5045657A

公开(公告)日：1991-09-03

申请号：US478833

申请日：1990-02-08

申请人： Klaus Claar ,  Jurgen Schrader ,  Josef Berger

发明人： Klaus Claar ,  Jurgen Schrader ,  Josef Berger

IPC分类号： H01H21/06 ,  E05B17/22 ,  H01H3/16 ,  H01H3/46 ,  H01H21/36 ,  H01H27/06

CPC分类号： E05B17/22 ,  H01H3/161 ,  H01H3/46

摘要： An actuating device for the mechanical positive actuation of a pressure-responsive switch utilizes a pivotably movable spring-loaded switch lever which, when activated by a control component movable in relation to the switch, is pivotable out of a lift-off position separate from the switch into a switch-triggering position bearing on the switch which is thereafter maintained in the bearing position. The switch lever is motionally coupled to the control component by spring force until the switch-triggering position is reached. It is possible to trigger the switch at an exact point, the switch lever is made bend-resistant and is pivotable about a joint and spring-loaded in the direction of its switch-triggering actuating advance. Since the switch lever is maintained in its switch-triggering position by the spring force, the control component can be moved further, uncoupled from the switch lever, after the latter has reached the switch-triggering position and moved through an additional angle to effect an additional mechanical function.

摘要翻译： 用于压力响应开关的机械正致动的致动装置利用可枢转运动的弹簧加载的开关杆，当开关相对于可移动的控制部件启动时，该开关杆可从与 切换到位于开关上的开关触发位置，此后保持在轴承位置。 开关杆通过弹簧力动作地联接到控制部件，直到达到开关触发位置。 可以在一个确切的点触发开关，开关杆被制成抗弯曲的并且可以围绕接头枢转，并且在其开关触发启动方向上弹簧加载。 由于开关杆通过弹簧力保持在其开关触发位置，所以控制部件可以在开关杆已经到达开关触发位置并进一步移动到另外的角度之后进一步移动，与开关杆脱开 额外的机械功能。

公开(公告)号：US6146887A

公开(公告)日：2000-11-14

申请号：US123708

申请日：1998-07-28

申请人： Jurgen Schrader ,  Axel Godecke

发明人： Jurgen Schrader ,  Axel Godecke

IPC分类号： C12N15/09 ,  A61K31/70 ,  A61K38/00 ,  A61K47/48 ,  A61K48/00 ,  A61P9/00 ,  A61P9/10 ,  A61P9/12 ,  C12N9/00 ,  C12N9/02 ,  C12N15/85 ,  C12R1/91 ,  C12N15/00

CPC分类号： C12N9/0075 ,  A61K47/48776 ,  C12N15/85 ,  A61K38/00 ,  A61K48/00 ,  C12N2800/108 ,  C12N2830/42

摘要： A DNA expression vector is described which is characterized in that it comprises a DNA sequence that codes a protein which possesses the biological activity of nitrogen monoxide synthase (NOS) and eukaryotic regulation elements, wherein said eukaryotic regulation elements result in the expression of said DNA sequence in eukaryotic cells, as well as the use of the expression vector for treatment or prevention of vascular disorders.

摘要翻译： 描述了DNA表达载体，其特征在于其包含编码具有一氧化氮合酶（NOS）和真核调节元件的生物活性的蛋白质的DNA序列，其中所述真核调节元件导致所述DNA序列的表达 在真核细胞中，以及使用表达载体治疗或预防血管疾病。

公开(公告)号：US5052740A

公开(公告)日：1991-10-01

申请号：US404191

申请日：1989-09-07

申请人： Theodor Bauer ,  Jurgen Schrader

发明人： Theodor Bauer ,  Jurgen Schrader

IPC分类号： B60J7/12 ,  B60J7/185 ,  B60J7/20

CPC分类号： B60J7/1204 ,  B60J7/1856

摘要： A folding top for vehicles has a common pivoting drive of a main strut and of a roof-skin retaining bow via mechanical drive members, by means of which pivoting drive of the folding top can be transferred from a stowed position retracted into a top box into a closed position, in which the roof-skin retaining bow rests on the top-box lid located in a covering position thereof. An automatically controlled lock of the main strut relative to the vehicle body in its erected end position is provided and associated with its uncoupling from the driving movement of the drive members. For locking the main strut fixedly to the vehicle body, there are catch devices which are assigned to the top columns and the catching advance of the which starts only after the erected end position of the main strut has already been reached, and the uncoupling from the driving movement of the drive members is activated via the catching advance of the catch means only when the main strut has been locked.

摘要翻译： 用于车辆的折叠顶部具有主支柱和通过机械驱动构件的屋顶皮肤保持弓的共同的枢转驱动，通过该折叠顶部的折叠顶部的枢转驱动可以从缩回到顶盒中的收起位置转移到 关闭位置，其中屋顶护皮弓搁置在位于其覆盖位置的顶盒盖上。 提供了主支柱相对于其竖立端部位置处的车身的自动控制的锁定，并且与其与驱动构件的驱动运动的分离相关联。 为了将主支柱固定地固定在车体上，存在被分配到顶部列的抓持装置，并且仅在已经到达主支柱的竖立终点位置之后才开始抓取装置，并且从 驱动构件的驱动运动仅在主支柱被锁定时通过捕捉装置的捕捉提前被激活。

公开(公告)号：US20100048501A1

公开(公告)日：2010-02-25

申请号：US12293983

申请日：2007-03-21

申请人： Jurgen Schrader ,  Christa Muller ,  All El-Tayeb ,  Jamshed Iqbal

发明人： Jurgen Schrader ,  Christa Muller ,  All El-Tayeb ,  Jamshed Iqbal

IPC分类号： A61K31/7076 ,  C07H19/20 ,  G01N33/53 ,  A61P19/00 ,  A61P25/00

CPC分类号： C07H19/20

摘要： A phosphorylated A2A receptor agonist providing agonist properties on the A2A receptor after dephosphorylation the phosphorylated A2A receptor agonist comprises a ribosyl moiety and a purine moiety and being phosphorylated at the 5′-position of the ribose moiety except adenosine monophosphate (AMP), adenosine diphosphate (ADP) or adenosine triphosphate (ATP), a medicament containing the compound of the invention including ADP and the use of the compound of the invention including ATP and ADP for several medical indications e. g. inflammatory events. In particular, compounds of formula (I) are also disclosed.

摘要翻译： 在磷酸化A2A受体激动剂脱磷酸化后，在A2A受体上提供激动剂性质的磷酸化A2A受体激动剂包含核糖基部分和嘌呤部分，并且在核糖部分的5'-位被磷酸化，除了腺苷一磷酸（AMP），二磷酸腺苷 ADP）或三磷酸腺苷（ATP），含有包含ADP的本发明化合物的药物，以及包括ATP和ADP在内的多种医学适应症的本发明化合物的用途。 G。 炎性事件。 特别地，还公开了式（I）的化合物。

公开(公告)号：US06200304B1

公开(公告)日：2001-03-13

申请号：US09112519

申请日：1998-07-09

申请人： Jurgen Schrader

发明人： Jurgen Schrader

IPC分类号： A61M3100

CPC分类号： C12N15/86 ,  A61K48/00 ,  C12N9/0075 ,  C12N2750/14143

摘要： The present invention relates to a transfection system comprising one or more Infiltrator catheters, one or more non-viral nucleic acids, and, where appropriate, suitable ancillary substances and/or additives, and to its preparation and use in somatic gene therapy.

摘要翻译： 本发明涉及一种转染系统，其包含一种或多种浸润器导管，一种或多种非病毒核酸，以及适当的合适的辅助物质和/或添加剂，以及其在体细胞基因治疗中的制备和用途。

公开(公告)号：US6149936A

公开(公告)日：2000-11-21

申请号：US123624

申请日：1998-07-28

申请人： Jurgen Schrader ,  Axel Godecke

发明人： Jurgen Schrader ,  Axel Godecke

IPC分类号： C12N15/09 ,  A61K31/70 ,  A61K38/00 ,  A61K47/48 ,  A61K48/00 ,  A61P9/00 ,  A61P9/10 ,  A61P9/12 ,  C12N9/00 ,  C12N9/02 ,  C12N15/85 ,  C12R1/91 ,  A61K3/127 ,  A61K31/7088

CPC分类号： C12N9/0075 ,  A61K47/48776 ,  C12N15/85 ,  A61K38/00 ,  A61K48/00 ,  C12N2800/108 ,  C12N2830/42

摘要： A DNA expression vector is described which is characterized in that it comprises a DNA sequence that codes a protein which possesses the biological activity of nitrogen monoxide synthase (NOS) and eukaryotic regulation elements, wherein said eukaryotic regulation elements result in the expression of said DNA sequence in eukaryotic cells, as well as the use of the expression vector for treatment or prevention of vascular disorders.

摘要翻译： 描述了DNA表达载体，其特征在于其包含编码具有一氧化氮合酶（NOS）和真核调节元件的生物活性的蛋白质的DNA序列，其中所述真核调节元件导致所述DNA序列的表达 在真核细胞中，以及使用表达载体治疗或预防血管疾病。

公开(公告)号：US5707099A

公开(公告)日：1998-01-13

申请号：US718936

申请日：1996-09-24

申请人： Jurgen Schrader ,  Martin Lorenz ,  Stephan Orth

发明人： Jurgen Schrader ,  Martin Lorenz ,  Stephan Orth

IPC分类号： B60J7/22 ,  B60N2/90 ,  B62D35/00

CPC分类号： B60N2/44 ,  B60J7/223

摘要： On the cross traverse of at least one convertible automobile rollover bar, a wind net is supported on a span at least approximately the surface between the lateral members of the rollover bar. The upper edge of the wind net rests on an exterior side of the cross traverse in a tensioned manner, and the wind net itself extends down only to approximately the level of the vehicle edge.

摘要翻译： 在至少一个可转换的汽车翻车杆的横向横移上，风网至少在翻转杆的横向构件之间的表面上支撑在跨距上。 风网的上边缘以张紧的方式搁置在横向横移的外侧上，并且风网本身仅向下延伸到车辆边缘的大致水平。