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公开(公告)号:US08816274B2
公开(公告)日:2014-08-26
申请号:US13262217
申请日:2009-03-31
申请人: Kiyoshi Ogawa , Mitsutoshi Setou
发明人: Kiyoshi Ogawa , Mitsutoshi Setou
CPC分类号: H01J49/0004 , G01N1/06 , G01N1/286 , H01J49/0459
摘要: A sample stage (2) on which a sample (4) is placed can be reciprocally moved along a guide (5) by a driving mechanism (6). A cutter (9) which is moved in an X-Y plane by a driving mechanism (10) is placed at a sample cutting position (B). When the sample stage (2) is moved to the sample cutting position (B) and the cutter is driven with the height of the sample stage (2) being appropriately adjusted, an upper portion of the sample 4 is horizontally cut off with a predetermined thickness and a new sample analysis surface which was inside the sample 4 is exposed. Hence, by repeating a mass analysis for a predetermined measurement area at an analysis position (C) and a partial cutting of the sample 4 at the sample cutting position (B), it is possible to achieve a three-dimensional mass analysis imaging of the sample (4) without removing the sample (4) from the sample stage (2).
摘要翻译: 其上放置有样品(4)的样品台(2)可以通过驱动机构(6)沿引导件(5)往复运动。 通过驱动机构(10)在X-Y平面中移动的切割器(9)被放置在样品切割位置(B)。 当样品台(2)移动到样品切割位置(B)并且在适当调节样品台(2)的高度的情况下驱动切割器时,样品4的上部以预定的 厚度和样品4内部的新的样品分析表面露出。 因此,通过在样本切断位置(B)的分析位置(C)和样本4的部分切割重复对于预定测量区域的质量分析,可以实现三维质量分析成像 样品(4),而不从样品台(2)中移除样品(4)。
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公开(公告)号:US07501620B2
公开(公告)日:2009-03-10
申请号:US11362526
申请日:2006-02-27
申请人: Kiyoshi Ogawa , Yoshikazu Yoshida , Kozo Shimazu , Mitsutoshi Setou , Shuichi Shimma , Michisato Toyoda
发明人: Kiyoshi Ogawa , Yoshikazu Yoshida , Kozo Shimazu , Mitsutoshi Setou , Shuichi Shimma , Michisato Toyoda
CPC分类号: H01J49/40 , H01J49/0004 , H01J49/004 , H01J49/164 , H01J49/424
摘要: The present invention provides a laser irradiation mass spectrometer capable of analyzing components of living tissue or living cells with high accuracy. It includes a laser unit for irradiating a sample with a beam of laser light and controlling the irradiation spot of the laser beam on the sample; and a mass analyzer for performing a mass analysis of the ions generated at the irradiation spot, where the mass analyzer uses a frequency-driven ion trap and a time-of-flight mass spectrometer to carry out the mass analysis. The ion trap of this system assuredly traps ions having large mass to charge ratios, and enables the system to carry out analyses on samples of large molecules. Preferably, a digital driving method is used to drive the aforementioned frequency-driven ion trap. Also, a multi-turn time-of-flight mass spectrometer may preferably be used as the aforementioned time-of-flight mass spectrometer.
摘要翻译: 本发明提供能够高精度地分析活体组织或活细胞的成分的激光照射质谱仪。 它包括用激光束照射样品的激光单元,并将激光束的照射点控制在样品上; 以及质量分析器,用于对照射点产生的离子进行质量分析,质量分析仪使用频率驱动离子阱和飞行时间质谱仪进行质量分析。 该系统的离子阱确实捕获具有大质量与电荷比的离子,并使系统能够对大分子样品进行分析。 优选地,使用数字驱动方法来驱动上述频率驱动的离子阱。 此外,可以优选使用多匝飞行时间质谱仪作为上述飞行时间质谱仪。
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公开(公告)号:US20110315874A1
公开(公告)日:2011-12-29
申请号:US13254136
申请日:2009-03-05
申请人: Masahiro Ikegami , Kiyoshi Ogawa , Takahiro Harada
发明人: Masahiro Ikegami , Kiyoshi Ogawa , Takahiro Harada
IPC分类号: H01J49/26
CPC分类号: G01N27/628 , H01J49/0004 , H01J49/0413
摘要: When specimen (4) is placed on specimen stage (2), controller (32)—via the stage driver (33) and drive mechanism (6)—moves the specimen stage (2) by a predetermined step pitch according to the magnification factor in the X-direction and the Y-direction, and the image pickup unit (7) acquires a microscopic observation image of the specimen (4) after each move. The microscopic observation image that is acquired and the position data of the specimen stage (2) when the image is acquired are stored in memory (321). When a plurality of microscopic observation images of the areas that are adjacent on the specimen (2) are obtained, the image integration processor (322) uses the position data to join the microscopic observation images. When a plurality of microscopic observation images that encompasses the entirety of the specimen (2) is all joined together to form a specimen observation image, the specimen observation image is displayed on a display unit 37. The user then specifies the desired measurement region based on the specimen observation image that is high in spatial resolution and covering a wide area. Because of this, there is no need to repeat the steps of image pickup and mass spectrometry even when performing a mass spectrometry over a wide area, allowing an efficient measurement.
摘要翻译: 当样本(4)放置在样本台(2)上时,控制器(32) - 通过平台驱动器(33)和驱动机构(6) - 根据放大系数将样品台(2)以预定的间距移动 在X方向和Y方向上,并且摄像单元(7)在每次移动之后获取样本(4)的显微镜观察图像。 获取的显微镜观察图像和获取图像时的样本台(2)的位置数据被存储在存储器(321)中。 当获得在样本(2)上相邻的区域的多个显微镜观察图像时,图像合成处理器(322)使用位置数据来连接显微镜观察图像。 当包含整个样本(2)的多个显微镜观察图像全部结合在一起以形成样本观察图像时,将样本观察图像显示在显示单元37上。然后,用户基于 空间分辨率高,覆盖面广的样本观察图像。 因此,即使在宽范围内进行质谱分析,也不需要重复图像拾取和质谱分析步骤,从而能够进行有效的测量。
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公开(公告)号:US20090230301A1
公开(公告)日:2009-09-17
申请号:US12355462
申请日:2009-01-16
申请人: Osamu furuhashi , Takahiro Harada , Hideaki Izumi , Kiyoshi Ogawa
发明人: Osamu furuhashi , Takahiro Harada , Hideaki Izumi , Kiyoshi Ogawa
CPC分类号: H01J49/4265
摘要: Disclosed is a mass spectrometry apparatus and method capable of providing enhanced analysis sensitivity in a mass spectrometric analysis for a small amount of ions. A quadrupole rod-type ion guide is employed to temporarily accumulate ions to be introduced into an ion trap, and ions are introduced into the ion guide in an amount less than a saturated ion amount in the ion guide, and accumulated in an exit end of the ion guide. As compared with an octopole rod-type ion guide, the quadrupole rod-type ion guide has a higher ion-converging capability, and therefore can confine and hold a small amount of ions around an ion optical axis, although it is inferior in ion-accumulating capability. This makes it possible to efficiently introduce the ions into the ion trap through two openings of an electric field-correcting electrode and an entrance endcap electrode, so as to perform a high-sensitive analysis.
摘要翻译: 公开了能够在少量离子的质谱分析中提供增强的分析灵敏度的质谱装置和方法。 采用四极杆型离子导向器暂时积聚离子以引入离子阱,并将离子以小于离子导向器中的饱和离子量的量引入离子导向器中,并且累积在 离子导向。 与八极杆型离子导向器相比,四极杆型离子导向器具有较高的离子收敛能力,因此可以限制和保持离子光轴周围的少量离子,尽管其离子 - 积累能力。 这使得可以通过电场校正电极和入口端帽电极的两个开口有效地将离子引入离子阱中,从而进行高灵敏度分析。
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公开(公告)号:US08650721B2
公开(公告)日:2014-02-18
申请号:US12676800
申请日:2008-09-11
申请人: Kiyoshi Ogawa , Goushu Kataoka , Katsuyasu Ono , Yuji Sakata , Hitoshi Futaki , Masanao Yamazaki
发明人: Kiyoshi Ogawa , Goushu Kataoka , Katsuyasu Ono , Yuji Sakata , Hitoshi Futaki , Masanao Yamazaki
CPC分类号: B60R22/12 , B60R22/22 , B60R2022/1806 , Y10T24/4047 , Y10T24/4086 , Y10T24/45241 , Y10T24/45623 , Y10T24/4736 , Y10T24/4745 , Y10T29/49826
摘要: A buckle device 10 for a seat belt includes: an anchor plate 11 that can be attached to a vehicle body side; a buckle 20 to which a tongue of the seat belt can be detachably attached; and a woven fabric 30 that is passed through hole portions 14, 26 formed respectively in the anchor plate 11 and the buckle 20, the woven fabric 30 being folded back so as to overlap at least triply and being sewn together in the overlapping part. A tip end portion 31a of the woven fabric 30 tucked into the inner side contacts the opposing buckle 20.
摘要翻译: 用于座椅安全带的带扣装置10包括:可附接到车体侧的锚板11; 安全带的舌头可拆卸地安装在其上的带扣20; 以及穿过分别形成在锚固板11和带扣20中的孔部分14,26的织物30,将织物30折叠成至少三重重叠并在重叠部分缝合在一起。 卷入内侧的织物30的前端部31a与相对的扣环20接触。
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公开(公告)号:US08286903B2
公开(公告)日:2012-10-16
申请号:US12945478
申请日:2010-11-12
申请人: Kiyoshi Ogawa , Masuo Matsuki
发明人: Kiyoshi Ogawa , Masuo Matsuki
IPC分类号: B65H75/48
CPC分类号: B60R22/4676 , B60R2022/287 , B60R2022/289
摘要: A retractor includes a slide nut that is caused to slide toward a tread head while rotating by a mesh between a first male screw groove and a female screw groove when the tread head is locked and a spindle rotates in a direction for unreeling a webbing, and a slider that is caused to slide toward the slide nut by a mesh between the female screw groove and a second male screw groove. A torsional rigidity of a second shaft part of a torsion bar is larger than that of a first shaft part, and a play is eliminated before a gap such that the slide nut and the slider are integrated.
摘要翻译: 牵开器包括滑动螺母,当滑动螺母被锁定并且主轴沿用于松开织带的方向旋转时,滑动螺母在通过第一外螺纹槽和内螺纹槽之间的网转动的同时朝向胎面头滑动,以及 滑动件通过内螺纹槽和第二外螺纹槽之间的网状物向滑动螺母滑动。 扭杆的第二轴部的扭转刚性大于第一轴部的扭转刚性,并且在滑动螺母和滑块一体化的间隙之前消除了间隙。
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公开(公告)号:US20120043407A1
公开(公告)日:2012-02-23
申请号:US13264870
申请日:2010-03-31
申请人: Kiyoshi Ogawa , Katsuyasu Ono , Yuichi Hamano
发明人: Kiyoshi Ogawa , Katsuyasu Ono , Yuichi Hamano
IPC分类号: B60R22/36
CPC分类号: B60R22/4628 , B60R2022/287 , B60R2022/4642
摘要: A seatbelt retractor having a switching device with a gas generator and a switch housing having a gas generator housing portion for accommodating the gas generator and a gas flow path that communicates with the gas generator housing portion so that gas generated by the gas generator passes through the gas flow path. Further, the gas generator housing portion and the gas flow path are formed in the switch housing in a curved shape, and a die-cut hole extending in a direction of the gas flow path on an opposite side of the gas flow path to the gas generator housing portion is blocked from the gas flow path by the gas generator.
摘要翻译: 一种安全带卷收器,具有具有气体发生器的开关装置和具有用于容纳气体发生器的气体发生器容纳部分和与气体发生器壳体部分连通的气体流路的开关壳体,使得由气体发生器产生的气体通过 气体流路。 此外,气体发生器壳体部分和气体流动通道在开关壳体中形成为弯曲形状,并且在气体流动路径的与气体的气体流动路径相对的一侧上延伸的冲切孔 发电机壳体部分被气体发生器从气体流动路径阻挡。
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公开(公告)号:US20110011969A1
公开(公告)日:2011-01-20
申请号:US12922839
申请日:2009-04-03
申请人: Kiyoshi Ogawa
发明人: Kiyoshi Ogawa
IPC分类号: B60R22/46
CPC分类号: B60R22/4676 , B60R22/4633 , B60R2022/4642
摘要: A seat belt retractor (10) is provided with: a spindle (12) around which a seat belt (B) is wound; a torsion bar (17) disposed in a cavity (27) of the spindle (12), an axial end portion of the torsion bar (17) being attached to an axial end portion of the spindle (12); a first pretensioner (16) that is attached to the spindle (12) at least during a collision so as to cause the spindle (12) to rotate in a retraction direction using a gas pressure; and a second pretensioner (18) that is attached to another axial end portion of the torsion bar (17) at least during a collision so as to cause the spindle (12) to rotate in the retraction direction via the torsion bar (17) using the gas pressure.
摘要翻译: 安全带卷收器(10)设有:一个主轴(12),一个安全带(B)绕在该主轴上; 设置在所述心轴(12)的空腔(27)中的扭杆(17),所述扭杆(17)的轴向端部附接到所述心轴(12)的轴向端部; 至少在碰撞期间附接到所述主轴(12)的第一预张紧器(16),以便使所述主轴(12)使用气压在回缩方向上旋转; 以及至少在碰撞期间附接到所述扭杆(17)的另一轴向端部的第二预张紧器(18),以便使所述主轴(12)经由所述扭杆(17)沿所述缩回方向旋转,所述第二预紧器(18)使用 气压。
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公开(公告)号:US20100018016A1
公开(公告)日:2010-01-28
申请号:US12522632
申请日:2007-12-03
申请人: Masaki Omiya , Kiyoshi Ogawa , Atsushi Tsuha
发明人: Masaki Omiya , Kiyoshi Ogawa , Atsushi Tsuha
IPC分类号: A44B1/08
CPC分类号: B60R22/24 , B60R22/203 , Y10T24/45524
摘要: A button of a shoulder position adjuster device is provided including an outer surface portion which, at a normal state, is generally continuous with an outer surface of a cover facing an inner space of a passenger compartment. Flexible left and right outer lateral walls are formed continuously with the outer surface portion and have lock portions which are locked on to a side member at the normal state and which are released from the locked state at the time of a pulling operation. Additionally, a pair of connecting walls are provided which extend from the outer surface portion towards a guide rail side in the left and right outer lateral walls and connect the latch pin.
摘要翻译: 提供了一种肩位置调节装置的按钮,其包括外表面部分,该外表面部分在正常状态下与面向乘客室内空间的盖的外表面大致连续。 灵活的左右外侧壁与外表面部分连续地形成,并且具有在正常状态下锁定在侧部构件上并且在拉动操作时从锁定状态释放的锁定部分。 此外,设置一对连接壁,其从外表面部分朝向左外侧壁和右外侧壁中的导轨侧延伸并连接闩锁销。
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公开(公告)号:US06446897B1
公开(公告)日:2002-09-10
申请号:US09518274
申请日:2000-03-03
申请人: Takashi Arima , Kenichi Morizane , Masuo Matsuki , Kiyoshi Ogawa , Katsuyasu Ono
发明人: Takashi Arima , Kenichi Morizane , Masuo Matsuki , Kiyoshi Ogawa , Katsuyasu Ono
IPC分类号: B60R2234
CPC分类号: F16D41/18 , B60R22/4628 , B60R2022/4642 , B60R2022/468
摘要: The present invention provides a seat belt system comprising: a moving element (36) rotatably received in a housing (26); a device (32) for applying a pressurized gas to the moving element (36) when abrupt deceleration occurs on a vehicle; a tensile member (40) responsive to movement of the moving element (36) extruded due to the pressurized gas to generate a rotational torque; and a clutch mechanism (44) for transmitting the rotational torque generated by the tensile member (40) to a retractor shaft (24) to rotate the shaft (24) in a webbing-winding direction.
摘要翻译: 本发明提供了一种安全带系统,包括:可旋转地容纳在壳体(26)中的移动元件(36); 用于当在车辆上发生急剧减速时,将加压气体施加到所述移动元件(36)的装置(32) 响应于由于加压气体挤出的移动元件(36)的移动而产生旋转扭矩的拉伸构件(40) 以及用于将由拉伸构件(40)产生的旋转扭矩传递到牵开器轴(24)以使轴(24)沿织带卷绕方向旋转的离合器机构(44)。
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