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    SURFACE ENHANCED RAMAN SPECTROSCOPY SENSOR, SYSTEM AND METHOD OF SENSING
    13.
    发明申请
    SURFACE ENHANCED RAMAN SPECTROSCOPY SENSOR, SYSTEM AND METHOD OF SENSING 有权
    表面增强拉曼光谱传感器，系统和感测方法

    公开(公告)号：US20140125976A1

    公开(公告)日：2014-05-08

    申请号：US14118801

    申请日：2011-05-20

    Applicant: Ansoon Kim ,  Zhiyong Li

    Inventor： Ansoon Kim ,  Zhiyong Li

    IPC: G01N21/65 ,  G01J3/44

    CPC classification number: G01N21/658 ,  B82Y15/00 ,  G01J3/44

    Abstract: A surface enhanced Raman spectroscopy (SERS) sensor, system and method employ nanorods and independent nanoparticles that interact. The sensor includes at least two spaced apart nanorods attached at first ends to a substrate and an independent nanoparticle. Second ends of the nanorods are movable into close proximity to one another and include a Raman active surface. The nanoparticle has a functionalized surface that includes a Raman signal generator. An interaction between the nanoparticle and the nanorod second ends in close proximity is detectable. The system includes the SERS sensor, an illumination source and a Raman signal detector. The method includes illuminating the interaction of the nanoparticle and the nanorods with an analyte, and detecting an effect on a Raman signal caused by the analyte.

    Abstract translation: 表面增强拉曼光谱（SERS）传感器，系统和方法采用纳米棒和独立纳米粒子相互作用。 传感器包括至少两个间隔开的纳米棒，其在第一端附着到基底和独立的纳米颗粒。 纳米棒的第二端可以彼此靠近移动并且包括拉曼活性表面。 纳米颗粒具有包括拉曼信号发生器的官能化表面。 纳米颗粒和纳米棒第二末端之间的相互作用是可以接近的。 该系统包括SERS传感器，照明源和拉曼信号检测器。 该方法包括用分析物照射纳米颗粒和纳米棒的相互作用，并检测由分析物引起的对拉曼信号的影响。

    FREE-STANDING STRUCTURES FOR MOLECULAR ANALYSIS
    14.
    发明申请
    FREE-STANDING STRUCTURES FOR MOLECULAR ANALYSIS 审中-公开
    用于分子分析的自由结构

    公开(公告)号：US20130107250A1

    公开(公告)日：2013-05-02

    申请号：US13282606

    申请日：2011-10-27

    Applicant: Wei Wu ,  Zhiyong Li ,  Ansoon Kim ,  Min Hu ,  Michael Josef Stuke

    Inventor： Wei Wu ,  Zhiyong Li ,  Ansoon Kim ,  Min Hu ,  Michael Josef Stuke

    IPC: G01N21/01

    CPC classification number: B82Y40/00 ,  B82Y15/00 ,  G01N21/554 ,  G01N21/658

    Abstract: A structure for molecular analysis is disclosed. The structure includes a nanostructure and a nanoparticle attached to the nanostructure, wherein the nanostructure is free-standing and wherein the nanoparticle, the nanostructure or both the nanoparticle and the nanostructure are coated with a metal coating; or a plurality of nanoparticles, wherein the plurality of nanoparticles is free-standing and wherein each nanoparticle in the plurality is coated with a metal coating and is separated from one other nanoparticle or two other nanoparticles by a distance of 0.5 nm to 1 nm. A method for preparing the structure for molecular analysis is also disclosed.

    Abstract translation: 公开了一种用于分子分析的结构。 该结构包括纳米结构和连接到纳米结构的纳米颗粒，其中纳米结构是独立的，并且其中纳米颗粒，纳米结构或纳米颗粒和纳米结构二者都涂覆有金属涂层; 或多个纳米颗粒，其中所述多个纳米颗粒是独立的，并且其中所述多个纳米颗粒中的每个纳米颗粒涂覆有金属涂层，并且与另外一个纳米颗粒或两个其它纳米颗粒分开0.5nm至1nm的距离。 还公开了用于分子分析结构的制备方法。

    IMPLANTABLE NANOSENSOR
    15.
    发明申请
    IMPLANTABLE NANOSENSOR 有权
    可植入的纳米传感器

    公开(公告)号：US20150173656A1

    公开(公告)日：2015-06-25

    申请号：US14406601

    申请日：2012-07-29

    Applicant: Steven Barcelo ,  Zhiyong Li ,  Ansoon Kim ,  Gary Gibson

    Inventor： Steven Barcelo ,  Zhiyong Li ,  Ansoon Kim ,  Gary Gibson

    IPC: A61B5/1459 ,  A61B5/00

    CPC classification number: A61B5/1459 ,  A61B5/0075 ,  A61B5/6862 ,  G01N21/658

    Abstract: An implantable nanosensor includes a stent to be implanted inside a fluid conduit. The stent has a well in a surface of the stent. The implantable nanosensor further includes a nanoscale-patterned sensing substrate disposed in the well. The nanoscale-patterned sensing substrate is to produce an optical scattering response signal indicative of a presence of an analyte in a fluid carried by the fluid conduit when interrogated by an optical stimulus signal.

    Abstract translation: 可植入纳米传感器包括待植入流体导管内的支架。 支架在支架表面有一个井。 可植入纳米传感器还包括设置在井中的纳米级图案感测基片。 纳米级图案化感测衬底将产生光学散射响应信号，该信号指示由光学刺激信号询问时由流体导管携带的流体中的分析物的存在。

    APPARATUS FOR PERFORMING A SENSING APPLICATION
    16.
    发明申请
    APPARATUS FOR PERFORMING A SENSING APPLICATION 有权
    执行感应应用的装置

    公开(公告)号：US20150116706A1

    公开(公告)日：2015-04-30

    申请号：US14394287

    申请日：2012-04-24

    Applicant: Steven Barcelo ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Ansoon Kim

    Inventor： Steven Barcelo ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Ansoon Kim

    IPC: G01N21/65

    CPC classification number: G01N21/658 ,  B82Y15/00 ,  G01N2201/06113 ,  Y10S977/954

    Abstract: An apparatus for performing a sensing application includes a reservoir to contain a solution, a dispenser to dispense the solution from the reservoir, and a substrate having a plurality of nano-fingers positioned to receive the dispensed solution, in which the plurality of nano-fingers are flexible, such that the plurality of nano-fingers are configurable with respect to each other. The apparatus also includes an illumination source to illuminate the received solution, an analyte introduced around the plurality of nano-fingers, and the plurality of nano-fingers, in which light is to be emitted from the analyte in response to being illuminated. The apparatus further includes a detector to detect the light emitted from the analyte.

    Abstract translation: 用于执行感测应用的装置包括容纳溶液的储存器，用于从储存器分配溶液的分配器以及具有多个纳米手指的基板，该多个纳米手指定位成接收分配的溶液，其中多个纳米手指 是柔性的，使得多个纳米手指可相对于彼此配置。 所述装置还包括照亮所接收的溶液的照明源，围绕所述多个纳米手指引入的分析物和所述多个纳米手指，其中光将响应于被照亮从分析物发射。 该装置还包括检测器，用于检测从分析物发射的光。

    HYBRID NANOSTRUCTURES FOR MOLECULAR ANALYSIS
    20.
    发明申请
    HYBRID NANOSTRUCTURES FOR MOLECULAR ANALYSIS 有权
    用于分子分析的混合纳米结构

    公开(公告)号：US20140024131A1

    公开(公告)日：2014-01-23

    申请号：US14006721

    申请日：2011-03-23

    Applicant: Ansoon Kim ,  Zhiyong Li ,  Stanley R. Williams

    Inventor： Ansoon Kim ,  Zhiyong Li ,  Stanley R. Williams

    IPC: G01N21/00

    CPC classification number: G01N21/00 ,  G01N21/554 ,  G01N21/648 ,  G01N21/658

    Abstract: A hybrid nanostructure for molecular analysis is disclosed. The structure includes a plurality of nanofingers wherein each nanofinger is coated with a metal coating, is attached at one end to a substrate, and is freely bendable along its length such that the second ends of each nanofinger are capable of movement toward each other to form a cavity. The structure further includes a nanoparticle trapped in the cavity. An array of hybrid nanostructures and a method for fabricating the hybrid nanostructures are also disclosed.

    Abstract translation: 公开了用于分子分析的杂化纳米结构。 该结构包括多个纳米针，其中每个纳米针涂覆有金属涂层，其一端连接到基底，并且可沿其长度自由弯曲，使得每个纳米针的第二端能够朝向彼此移动以形成 一个空腔。 该结构还包括捕获在空腔中的纳米颗粒。 还公开了一系列混合纳米结构和制备混合纳米结构的方法。

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