Method of fixing rail molecule and nano transport device
    11.
    发明授权
    Method of fixing rail molecule and nano transport device 失效
    轨道分子和纳米输送装置的固定方法

    公开(公告)号:US08088739B2

    公开(公告)日:2012-01-03

    申请号:US11919640

    申请日:2005-11-21

    IPC分类号: A61K38/16 C07K14/00

    摘要: An object is to move a rail molecule by means of a biomolecular motor deposited on a base and inactivate the biomolecular motor through irradiation with light having a predetermined wavelength, to thereby readily and reliably fix the rail molecule at a predetermined position, while orienting the rail molecule in a predetermined direction without employment of any reagent. A method for fixing a rail molecule which has polarity and on which a biomolecular motor moves in a direction corresponding to the polarity includes depositing a biomolecular motor on a base; moving a rail molecule by means of the biomolecular motor; and inactivating the biomolecular motor by irradiating the biomolecular motor with light having a predetermined wavelength when the rail molecule reaches a predetermined position, to thereby fix the rail molecule so that it is oriented in a predetermined direction.

    摘要翻译: 目的是通过沉积在基底上的生物分子马达来移动轨道分子,并通过用具有预定波长的光照射来灭活生物分子马达,从而容易且可靠地将轨道分子固定在预定位置,同时定向轨道 分子在预定方向上而不使用任何试剂。 固定具有极性的轨道分子的方法,其中生物分子马达在与极性相对应的方向上移动,包括在基底上沉积生物分子马达; 通过生物分子马达移动轨道分子; 并且当轨道分子到达预定位置时通过用具有预定波长的光照射生物分子马达来使生物分子马达失活,从而固定轨道分子使其沿预定方向取向。

    Nanopump system
    15.
    发明授权
    Nanopump system 失效
    纳米泵系统

    公开(公告)号:US06955670B2

    公开(公告)日:2005-10-18

    申请号:US10170774

    申请日:2002-06-13

    摘要: A self-contained delivery device for delivery a selected volume of stored electrolyte solution at selected time intervals is disclosed. The device includes a housing having a delivery port, a chamber containing an upstream supply reservoir for holding a quantity of electrolyte solution, a downstream delivery reservoir for receiving electrolyte solution from the supply reservoir and, disposed between the two reservoirs, a membrane having a plurality of flow-through channels extending between the two reservoirs. A pair of electrodes placed in the chamber on either side of the membrane and controlled by a controller contained within the housing for pumping selected quantities of the electrolyte solution at selected time intervals. The device includes a chamber, and a membrane disposed in said chamber and having a channel extending between an upstream chamber region, where the said channel has a selected minimum cross-sectional dimension in the range between 2 and 100 nm.

    摘要翻译: 公开了一种用于以选定的时间间隔递送选定体积的储存电解质溶液的独立输送装置。 该装置包括具有输送口的壳体,容纳用于保持一定数量的电解质溶液的上游供应储存器的室,用于从供应储存器接收电解质溶液的下游输送储存器,以及设置在两个储存器之间的膜, 的两个储存器之间延伸的流通通道。 一对电极放置在膜的两侧的腔室中,并由包含在壳体内的控制器控制,用于以选定的时间间隔泵送选定量的电解质溶液。 该装置包括一个室和一个设置在所述室中并具有在上游室区域之间延伸的通道的膜,其中所述通道具有在2和100nm之间范围内的选定的最小横截面尺寸。

    Wireless technique for microactivation
    16.
    发明授权
    Wireless technique for microactivation 失效
    微激活的无线技术

    公开(公告)号:US06588208B1

    公开(公告)日:2003-07-08

    申请号:US10058887

    申请日:2002-01-28

    申请人: Ken Clements

    发明人: Ken Clements

    IPC分类号: F01B2910

    摘要: The present invention is a method and apparatus for achieving high work output per unit volume in micro-robotic actuators, and in particular TiNi actuators. Such actuators are attractive as a means of powering nano-robotic movement, and are being developed for manipulation of structures at near the molecular scale. In these very small devices (one micron scale), one means of delivery of energy is by electron beams. Movement of mechanical structures a few microns in extent has been demonstrated in a scanning electron microscope. Results of these and subsequent experiments will be described, with a description of potential structures for fabricating moving a microscopic x-y stage.

    摘要翻译: 本发明是一种用于在微型机器人致动器,特别是TiNi致动器中实现每单位体积的高工作输出的方法和装置。 这样的致动器作为对纳米机器人运动的供电的手段是有吸引力的,并且正在开发用于在分子规模附近的结构的操纵。 在这些非常小的器件(一微米级)中,一种能量传递方式是电子束。 已经在扫描电子显微镜中证明了在几微米范围内的机械结构的移动。 将描述这些和随后的实验的结果,并描述了用于制造移动微观x-y阶段的潜在结构。

    Nanopump system
    17.
    发明申请
    Nanopump system 失效
    纳米泵系统

    公开(公告)号:US20030013186A1

    公开(公告)日:2003-01-16

    申请号:US10170774

    申请日:2002-06-13

    IPC分类号: B01L003/02 C12M001/34

    摘要: A self-contained delivery device for delivery a selected volume of stored electrolyte solution at selected time intervals is disclosed. The device includes a housing having a delivery port, and contained within the housing, a chamber containing an upstream supply reservoir for holding a quantity of electrolyte solution, a downstream delivery reservoir for receiving electrolyte solution from the supply reservoir and, disposed between the two reservoirs, a membrane having a plurality of flow-through channels extending between the two reservoirs. A pair of electrodes placed in the chamber on either side of the membrane are controlled by a controller contained within the housing, for pumping selected quantities of the electrolyte solution at selected time intervals. The invention also includes a device for detecting a target nucleic acid sequence contained in a solution of solution of nucleic acid fragments. The device includes a chamber, and a membrane disposed in said chamber and having a channel extending between an upstream chamber region, where the said channel has a selected minimum cross-sectional dimension in the range between 2 and 100 nm. Attached to a wall portion of the channel, is a capture nucleic acid having a sequence complementary to the target sequence. Upstream and downstream electrodes disposed in the upstream and downstream chamber regions, respectively, are in contact with electrolyte solution placed in the corresponding chamber regions. A controller in the device includes a power source operatively connected to the electrodes for applying a selected voltage potential across the channel, to move individual nucleic acid sequences contained in the solution through the channel, where the sequences can hybridize to complementary target sequences bound to the channel wall portion.

    摘要翻译: 公开了一种用于以选定的时间间隔递送选定体积的储存电解质溶液的独立输送装置。 该装置包括具有输送端口并且容纳在壳体内的壳体,容纳用于保持一定数量的电解质溶液的上游供应储存器的室,用于从供应储存器接收电解质溶液的下游输送储存器,以及设置在两个储存器 ,具有在两个储存器之间延伸的多个流通通道的膜。 放置在膜的任一侧的腔室中的一对电极由包含在壳体内的控制器控制,用于以选定的时间间隔泵送选定量的电解质溶液。 本发明还包括用于检测核酸片段溶液中包含的靶核酸序列的装置。 该装置包括一个室和一个设置在所述室中并具有在上游室区域之间延伸的通道的膜,其中所述通道具有在2和100nm之间范围内的选定的最小横截面尺寸。 连接到通道的壁部分,是具有与靶序列互补的序列的捕获核酸。 分别设置在上游和下游室区域中的上游和下游电极与放置在相应室区域中的电解质溶液接触。 器件中的控制器包括可操作地连接到电极的电源,用于在通道上施加选定的电压电位,以通过通道移动溶液中包含的各个核酸序列,其中序列可与与 通道壁部分。

    Mini notched turbine generator
    19.
    发明授权

    公开(公告)号:US09618002B1

    公开(公告)日:2017-04-11

    申请号:US14475663

    申请日:2014-09-03

    摘要: The present invention is turbine generator capable of integration into a bio-physiological or microfluidic system. The generator can convert biomechanical energy into electrical energy by using electromagnetic subsystems to transform the kinetic energy to electricity. These systems have the potential to convert hydraulic energy (such as flow of body fluid, blood flow, contraction of blood vessel, dynamic fluid in nature) into electric energy that may be sufficient for self-powering nano/micro devices and systems, such as artificial organs, valves, sensors, micro motors, and micro robots. The system incorporates a new turbine model having, notched blades; a rotor in levitation; and a special casing capable of integration into a bio-physiological or microfluidic system.

    Method for creating micro/nano wind energy gathering devices
    20.
    发明授权
    Method for creating micro/nano wind energy gathering devices 有权
    创建微/纳风力采集装置的方法

    公开(公告)号:US07950143B2

    公开(公告)日:2011-05-31

    申请号:US11842441

    申请日:2007-08-21

    IPC分类号: H05K3/30

    摘要: Method for manufacturing small wind energy gathering devices, for example, of geometrical dimensions tip to ⅛th of an inch (microdevices), employing micro-fabrication techniques. For example, three-dimensional single chemical composition parts of a small wind energy gathering device are manufactured using two-photon three dimensional lithography. Preferably, a plurality of such parts are manufactured in parallel, thereby optimizing the production process. The plurality of parts may be handled and assembled using precision instruments such as micro-tweezers, micro-scissors, and holographic lasers. Nanowires may be used to interconnect a plurality of the microdevices together, or to connect components of a particular microdevice. These nanowires are produced in nanowire arrays and are attached to a common base structure. Additionally, a form of injection molding and polymer materials may be utilized in the manufacturing of the small wind energy gathering devices (microdevices), which provide protective coatings and surfaces of reduced friction.

    摘要翻译: 使用微加工技术制造小型风能采集装置的方法,例如几何尺寸尖端到英寸(微型装置)。 例如,使用双光子三维光刻制造小型风能采集装置的三维单一化学成分部件。 优选地,并行地制造多个这样的部件,从而优化生产过程。 可以使用诸如微镊子,微型剪刀和全息激光器的精密仪器来处理和组装多个部件。 纳米线可以用于将多个微器件互连在一起,或者连接特定微器件的部件。 这些纳米线是以纳米线阵列生产的,并附着在共同的基底结构上。 此外,一种注射成型和聚合物材料的形式可以用于制造小型风能收集装置(微型装置),其提供保护性涂层和减少摩擦的表面。