Express system of soluble glutaminyl cyclase
    213.
    发明申请
    Express system of soluble glutaminyl cyclase 有权
    快速体系可溶性谷氨酰胺环化酶

    公开(公告)号:US20070281338A1

    公开(公告)日:2007-12-06

    申请号:US11331704

    申请日:2006-01-13

    Abstract: The present invention relates to a vector for expressing a soluble glutaminyl cyclase (QC) containing a sequence encoding QC, a fusion protein tag upstream of the sequence encoding QC, and a linker having at least one (His)x-tag between the sequence encoding QC and the fusion protein tag, wherein x is an integer of at least 6. Methods for expressing a soluble glutaminyl cyclase (QC) by the vector of the present invention are also provided.

    Abstract translation: 本发明涉及用于表达含有编码QC的序列的可溶性谷氨酰胺基环化酶(QC)的载体,编码QC的序列上游的融合蛋白标签,以及具有至少一个(His) 编码QC的序列和融合蛋白标签之间的tag,其中x是至少6的整数。还提供了通过本发明的载体表达可溶性谷氨酰胺酰基环化酶(QC)的方法。

    Motion actuator
    214.
    发明授权
    Motion actuator 有权
    运动执行器

    公开(公告)号:US07301257B2

    公开(公告)日:2007-11-27

    申请号:US11249477

    申请日:2005-10-14

    CPC classification number: H02N2/025

    Abstract: The present invention provides a shear motion driven motion actuator. The motion actuator provides a plurality of driving modes to drive a main body, including the inertial drive mode, the friction drive mode and the scanning mode. The motion actuator comprises a base having a V-shape concave groove and a main body having a V-shape convex. A plurality of piezoelectric elements is provided on the base to drive the main body using the shearing deformation force of the piezoelectric elements. The present invention also provides motion control using a variety of driving modes to achieve stable, high resolution and linear driving of the main body along the base.

    Abstract translation: 本发明提供一种剪切运动驱动运动致动器。 运动致动器提供多种驱动模式来驱动主体,包括惯性驱动模式,摩擦驱动模式和扫描模式。 运动致动器包括具有V形凹槽的基座和具有V形凸起的主体。 多个压电元件设置在基座上,以使用压电元件的剪切变形力驱动主体。 本发明还提供使用各种驱动模式的运动控制,以实现主体沿基座的稳定,高分辨率和线性驱动。

    High repetition rate visible optical parametric oscillator
    215.
    发明授权
    High repetition rate visible optical parametric oscillator 有权
    高重复率可见光参量振荡器

    公开(公告)号:US07298545B2

    公开(公告)日:2007-11-20

    申请号:US11318234

    申请日:2005-12-23

    CPC classification number: G02F1/39 G02F1/3558 G02F2202/20 G02F2203/05

    Abstract: A tunable coherent light source includes a pump laser for generating a pump beam and an optical parametric oscillator including a crystal exhibiting an output curve for a pump beam of a defined wavelength, the output curve defining wavelengths of signal and idler outputs based on periodically poled grating periods of the crystal. The crystal has a plurality of segments associated with a plurality of grating periods of the output curve, each segment of the plurality of segments having a different crystal structure. At least one of the plurality of segments comprises a crystal structure combining at least two of the grating periods A heating device heats the crystal to an elevated operating temperature and is adjustable for adjusting the output wavelengths of each of the segments.

    Abstract translation: 可调谐相干光源包括用于产生泵浦光束的泵浦激光器和包括具有用于定义波长的泵浦光束的输出曲线的晶体的光学参数振荡器,该输出曲线基于周期性极化光栅来定义信号波形和惰轮输出 水晶时期。 晶体具有与输出曲线的多个光栅周期相关联的多个段,多个段中的每个段具有不同的晶体结构。 多个区段中的至少一个包括结合至少两个光栅周期的晶体结构。加热装置将晶体加热到升高的工作温度,并且可调节以调节每个段的输出波长。

    Method of cross-linking peptides
    217.
    发明申请
    Method of cross-linking peptides 失效
    交联肽的方法

    公开(公告)号:US20070190616A1

    公开(公告)日:2007-08-16

    申请号:US11649176

    申请日:2007-01-03

    CPC classification number: C12N9/104 C07K1/1075 C12P21/00

    Abstract: A method of cross-linking a peptide to form a homopolymer of the peptide, to immobilize the peptide on a solid phase and to enhance antigenicity of the peptide is disclosed. The method comprises the steps of preparing a fusion peptide by incorporating a cross-linking segment including a tetrapeptide sequence Q-X-K-(S/T) (SEQ ID NO: 15) into the peptide and cross-linking the peptide by a glutaminase.

    Abstract translation: 公开了将肽交联以形成肽的均聚物的方法,以将肽固定在固相上并增强肽的抗原性。 该方法包括通过将包含四肽序列Q-X-K-(S / T)(SEQ ID NO:15)的交联链段并入肽中并通过谷氨酰胺酶交联肽来制备融合肽的步骤。

    System for measurement of the height, angle and their variations of the surface of an object
    218.
    发明授权
    System for measurement of the height, angle and their variations of the surface of an object 有权
    用于测量物体表面的高度,角度及其变化的系统

    公开(公告)号:US07247827B1

    公开(公告)日:2007-07-24

    申请号:US11443027

    申请日:2006-05-31

    CPC classification number: G01Q20/02 G11B7/0909

    Abstract: A system for measurement of the height, angle and their variations of the surface of an object comprises a measurement module and an astigmatic optical path mechanism. The optical path mechanism makes a laser beam pass a lens assembly and focus on an object. The reflected light passes the lens assembly and an astigmatic lens, arriving at the photo sensor assembly, forming a light spot thereon. The translational displacements of the object are measured by the variations in shape of the light spot on the photo sensors. The angular displacements of the object are measured accordingly by the movement of the light spot on the photo sensors.

    Abstract translation: 用于测量物体表面的高度,角度及其变化的系统包括测量模块和散光光路机构。 光路机构使激光束通过透镜组件并聚焦在物体上。 反射光通过透镜组件和散光透镜,到达光传感器组件,在其上形成光点。 物体的平移位移是通过光传感器上光点的形状变化来测量的。 物体的角位移相应地通过光点在光传感器上的移动来测量。

    Microarray biochemical reaction device
    219.
    发明申请
    Microarray biochemical reaction device 审中-公开
    微阵列生化反应装置

    公开(公告)号:US20070087353A1

    公开(公告)日:2007-04-19

    申请号:US11249449

    申请日:2005-10-14

    Abstract: The microarray biochemical reaction device of this invention integrates microfluidic trenches with a microarray to form a serpentine microchannel passing through all DNA probes provided in the microarray. A sample solution is introduced into the microchannel and scrambled into discrete plugs to induce droplet mixing. The discrete plugs are then shuttled through the entire microchannel (shuttle hybridization), sweeping over DNA probes to perform hybridization. Using chaotic mixing of droplets, the hybridization efficiency is enhanced and reaction time for hybridization is shortened. During shuttling, the plugs are thoroughly mixed by the natural re-circulating flows. Method for the preparation of the microarray biochemical reaction device is also disclosed.

    Abstract translation: 本发明的微阵列生物化学反应装置将微流体沟槽与微阵列整合,以形成穿过微阵列中提供的所有DNA探针的蛇形微通道。 将样品溶液引入微通道并加扰成离散的塞子以诱导液滴混合。 然后将离散的塞子穿过整个微通道(穿梭杂交),扫过DNA探针进行杂交。 通过混合液滴混合,杂交效率提高,杂交反应时间缩短。 在穿梭期间,塞子被自然的循环流充分混合。 还公开了用于制备微阵列生化反应装置的方法。

    Biological whole cell mass spectrometer
    220.
    发明授权
    Biological whole cell mass spectrometer 有权
    生物全细胞质谱仪

    公开(公告)号:US07161147B1

    公开(公告)日:2007-01-09

    申请号:US11134616

    申请日:2005-05-20

    CPC classification number: H01J49/0027

    Abstract: A method for identifying a biological organism that includes providing a biological sample corresponding to the biological organism, ionizing the biological sample to produce an ionized sample of the biological sample, performing a mass spectrometry analysis of the ionized sample, and identifying the biological organism in accordance with the mass spectrometry analysis.

    Abstract translation: 一种用于识别生物体的方法,包括提供对应于所述生物体的生物样品,电离所述生物样品以产生所述生物样品的离子化样品,对所述离子化样品进行质谱分析,以及根据 通过质谱分析。

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