公开(公告)号：US20080180662A1

公开(公告)日：2008-07-31

申请号：US11701045

申请日：2007-01-31

Applicant: Shih-Yuan Wang ,  Zhiyong Li

Inventor： Shih-Yuan Wang ,  Zhiyong Li

IPC: G01J3/44

CPC classification number: G01J3/44 ,  G01N21/658

Abstract: Raman systems include a radiation source, a radiation detector configured to detect Raman scattered radiation, and a Raman signal-enhancing structure. The Raman signal-enhancing structure includes a first layer of Raman signal-enhancing material, a substantially monomolecular layer of molecules disposed on at least a portion of the first layer of Raman signal-enhancing material, and a second layer of Raman signal-enhancing material disposed on at least a portion of the substantially monomolecular layer of molecules. The second layer of Raman signal-enhancing material is disposed on a side of the layer of molecules opposite the first layer of Raman signal-enhancing material. Methods of performing Raman spectroscopy include providing such a Raman signal-enhancing structure, providing an analyte on the Raman signal-enhancing structure, irradiating the analyte and the structure, and detecting Raman scattered radiation.

Abstract translation: 拉曼系统包括辐射源，被配置为检测拉曼散射辐射的辐射检测器和拉曼信号增强结构。 拉曼信号增强结构包括第一层拉曼信号增强材料，设置在第一层拉曼信号增强材料的至少一部分上的基本上单分子层的分子，以及第二层拉曼信号增强材料 设置在分子的基本单分子层的至少一部分上。 第二层拉曼信号增强材料设置在与第一层拉曼信号增强材料相对的分子层的一侧。 执行拉曼光谱的方法包括提供这样的拉曼信号增强结构，在拉曼信号增强结构上提供分析物，照射分析物和结构，以及检测拉曼散射辐射。

公开(公告)号：US07388661B2

公开(公告)日：2008-06-17

申请号：US11584446

申请日：2006-10-20

Applicant: Zhiyong Li ,  Zhaoning Yu

Inventor： Zhiyong Li ,  Zhaoning Yu

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01J3/44 ,  B82Y15/00 ,  G01N21/658

Abstract: NERS-active structures for use in Raman spectroscopy include protrusions extending from a surface of a substrate. A Raman signal-enhancing material is disposed on at least one surface of a first protrusion and at least one surface of a second protrusion. The Raman signal-enhancing material disposed on the first protrusion projects laterally in a direction generally towards the second protrusion, and the Raman signal-enhancing material disposed on the second protrusion projects laterally in a direction generally towards the first protrusion. At least a portion of the Raman signal-enhancing projecting from the first protrusion and at least a portion of the Raman signal-enhancing material projecting from the second protrusion may be separated by a distance of less than about 10 nanometers. Raman spectroscopy systems include such NERS-active structures, and methods for performing Raman spectroscopy include irradiating an analyte proximate such a NERS-active structure and detecting Raman-scattered radiation scattered by the analyte.

Abstract translation: 用于拉曼光谱的NERS-活性结构包括从基底表面延伸的突起。 拉曼信号增强材料设置在第一突起的至少一个表面和第二突起的至少一个表面上。 设置在第一突起上的拉曼信号增强材料在大致朝向第二突起的方向上横向突出，并且设置在第二突起上的拉曼信号增强材料在大致朝向第一突起的方向上横向突出。 从第一突起突出的拉曼增强信号的至少一部分和从第二突起突出的拉曼增强材料的至少一部分可以分开小于约10纳米的距离。 拉曼光谱系统包括这样的NERS-活性结构，并且用于进行拉曼光谱的方法包括照射靠近这样的NERS-活性结构的分析物并检测被分析物散射的拉曼散射辐射。

公开(公告)号：US20080094621A1

公开(公告)日：2008-04-24

申请号：US11584446

申请日：2006-10-20

Applicant: Zhiyong Li ,  Zhaoning Yu

Inventor： Zhiyong Li ,  Zhaoning Yu

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01J3/44 ,  B82Y15/00 ,  G01N21/658

Abstract: NERS-active structures for use in Raman spectroscopy include protrusions extending from a surface of a substrate. A Raman signal-enhancing material is disposed on at least one surface of a first protrusion and at least one surface of a second protrusion. The Raman signal-enhancing material disposed on the first protrusion projects laterally in a direction generally towards the second protrusion, and the Raman signal-enhancing material disposed on the second protrusion projects laterally in a direction generally towards the first protrusion. At least a portion of the Raman signal-enhancing projecting from the first protrusion and at least a portion of the Raman signal-enhancing material projecting from the second protrusion may be separated by a distance of less than about 10 nanometers. Raman spectroscopy systems include such NERS-active structures, and methods for performing Raman spectroscopy include irradiating an analyte proximate such a NERS-active structure and detecting Raman-scattered radiation scattered by the analyte.

Abstract translation: 用于拉曼光谱的NERS-活性结构包括从基底表面延伸的突起。 拉曼信号增强材料设置在第一突起的至少一个表面和第二突起的至少一个表面上。 设置在第一突起上的拉曼信号增强材料在大致朝向第二突起的方向上横向突出，并且设置在第二突起上的拉曼信号增强材料在大致朝向第一突起的方向上横向突出。 从第一突起突出的拉曼增强信号的至少一部分和从第二突起突出的拉曼增强材料的至少一部分可以分开小于约10纳米的距离。 拉曼光谱系统包括这样的NERS-活性结构，并且用于进行拉曼光谱的方法包括照射靠近这样的NERS-活性结构的分析物并检测被分析物散射的拉曼散射辐射。

公开(公告)号：US07321422B2

公开(公告)日：2008-01-22

申请号：US10942482

申请日：2004-09-16

Applicant: Zhiyong Li ,  Shih-Yuan Wang

Inventor： Zhiyong Li ,  Shih-Yuan Wang

IPC: G01J3/44

CPC classification number: G01N21/658

Abstract: SERS-active structures including features having nanoscale dimensions are disclosed, including methods for forming such SERS-active structures and methods for forming a plurality of such SERS-active structures. Methods for performing SERS using SERS-active structures also are disclosed.

Abstract translation: 公开了包括具有纳米级尺寸的特征的SERS活性结构，包括形成这种SERS-活性结构的方法和形成多个这样的SERS-活性结构的方法。 还公开了使用SERS活性结构来执行SERS的方法。

公开(公告)号：US20070252131A1

公开(公告)日：2007-11-01

申请号：US11413476

申请日：2006-04-28

Applicant: William Tong ,  Duncan Stewart ,  R. Williams ,  Manish Sharma ,  Zhiyong Li ,  Gary Gibson

Inventor： William Tong ,  Duncan Stewart ,  R. Williams ,  Manish Sharma ,  Zhiyong Li ,  Gary Gibson

IPC: H01L29/06

CPC classification number: H01L21/76892 ,  H01L21/76823 ,  H01L23/5254 ,  H01L27/1052 ,  H01L2924/0002 ,  H01L2924/12044 ,  H01L2924/3011 ,  H01L2924/00

Abstract: A method of forming an electrical interconnect, which includes a first electrode, an interlayer of a programmable material disposed over at least a portion of the first electrode, and a second electrode disposed over the programmable material at a non-zero angle relative to the first electrode. The interlayer includes a modified region having differing electrical properties than the rest of the interlayer, sandwiched at the junction of the first electrode and the second electrode. The interlayer may be exposed to a focused beam to form the modified region.

Abstract translation: 一种形成电互连的方法，包括第一电极，设置在第一电极的至少一部分上的可编程材料的中间层，以及设置在可编程材料上的第二电极，相对于第一电极以非零角度 电极。 中间层包括夹在第一电极和第二电极的接合处的与中间层的其余部分不同的电特性的改性区域。 中间层可以暴露于聚焦光束以形成改质区域。

公开(公告)号：US20070103305A1

公开(公告)日：2007-05-10

申请号：US11269237

申请日：2005-11-08

Applicant: Alexandre Bratkovski ,  Zhiyong Li ,  Geoffrey Lyon ,  Philip Kuekes ,  Shih Wang ,  R. Williams

Inventor： Alexandre Bratkovski ,  Zhiyong Li ,  Geoffrey Lyon ,  Philip Kuekes ,  Shih Wang ,  R. Williams

IPC: G08B13/14 ,  G08B1/08 ,  G08B21/00

CPC classification number: G06K7/0008 ,  H04L67/12

Abstract: A multi-tiered network for gathering detected condition information includes a first tier having first tier nodes and a second tier having a second tier node. The second tier node is operable to receive detected condition information from at least one of the first tier nodes in a substantially autonomous manner. In addition, the second tier node is operable to at least one of store, process, and transmit the detected condition information. The network also includes a third tier having a third tier node configured to receive the detected condition information and to at least one of store and process the detected condition information.

Abstract translation: 用于收集检测到的条件信息的多层网络包括具有第一层节点的第一层和具有第二层节点的第二层。 第二层节点可操作以基本上自主的方式从至少一个第一层节点接收检测到的条件信息。 此外，第二层节点可操作以存储，处理和发送检测到的条件信息中的至少一个。 网络还包括第三层，其具有被配置为接收检测到的条件信息的第三层节点以及存储和处理检测到的条件信息中的至少一个。

公开(公告)号：US07177021B2

公开(公告)日：2007-02-13

申请号：US10942004

申请日：2004-09-14

Applicant: Shih-Yuan Wang ,  M. Saif Islam ,  Zhiyong Li

Inventor： Shih-Yuan Wang ,  M. Saif Islam ,  Zhiyong Li

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/658 ,  G01J3/10 ,  G01N21/774 ,  H01S3/1086 ,  H01S3/169 ,  H01S5/026 ,  H01S5/1021 ,  H01S5/183 ,  H01S5/423

Abstract: Integrated radiation source/amplifying structures for use in surface enhanced Raman spectroscopy (SERS) and hyper-SERS are disclosed. The structures include a radiation source integrated with a SERS-active structure that is provided within a resonant cavity. SERS and hyper-SERS systems employing the integrated radiation source/amplifying structures are disclosed. Methods of performing SERS and hyper-SERS are also disclosed.

Abstract translation: 公开了用于表面增强拉曼光谱（SERS）和超SERS的集成放射源/放大结构。 该结构包括与设置在谐振腔内的SERS-活性结构集成的辐射源。 公开了采用集成放射源/放大结构的SERS和超SERS系统。 还公开了执行SERS和超SERS的方法。

公开(公告)号：US20060255333A1

公开(公告)日：2006-11-16

申请号：US11129602

申请日：2005-05-12

Applicant: Philip Kuekes ,  Zhiyong Li

Inventor： Philip Kuekes ,  Zhiyong Li

IPC: H01L29/08

CPC classification number: G01N21/658

Abstract: The present invention provides a method of forming a controlled distribution of nano-particles on a surface. The method includes forming a layer of block copolymer having at least two types of blocks. Each type of block has a respective type of polymer. The block copolymer has an exposed surface and the blocks have exposed surface portions. The blocks are distributed on a substrate. The method also includes attaching nano-particles to the surface portions of at least one and less than all types of the blocks so that the attached particles form a controlled distribution on the surface of the block copolymer.

Abstract translation: 本发明提供了在表面上形成纳米颗粒受控分布的方法。 该方法包括形成具有至少两种类型的嵌段的嵌段共聚物层。 每种类型的块都具有相应类型的聚合物。 嵌段共聚物具有暴露的表面，并且嵌段具有暴露的表面部分。 这些块分布在基板上。 该方法还包括将纳米颗粒附着在至少一种且少于所有类型的嵌段的表面部分上，使得附着的颗粒在嵌段共聚物的表面上形成受控的分布。

公开(公告)号：US20060180480A1

公开(公告)日：2006-08-17

申请号：US11059258

申请日：2005-02-15

Applicant: Sean Zhang ,  Zhiyong Li ,  Zhang-Lin Zhou ,  William Tong ,  R. Williams ,  Yong Chen

Inventor： Sean Zhang ,  Zhiyong Li ,  Zhang-Lin Zhou ,  William Tong ,  R. Williams ,  Yong Chen

IPC: G01F1/64 ,  G01N33/487 ,  G01N27/26

CPC classification number: G01N33/5308 ,  G01N33/5438 ,  G01N2430/00

Abstract: A sensor array for sensing at least one of chemical moieties and biological moieties is provided. The sensor array comprises a plurality of working electrodes electrically associated with a reference electrode, each working electrode in combination with the reference electrode forming a transducer. Each working electrode is provided with a coating of a sensing element comprised of an ionizable moiety and a functional group sensitive to one of the chemical and/or biological moieties.

Abstract translation: 提供了用于感测化学部分和生物部分中的至少一个的传感器阵列。 传感器阵列包括与参考电极电连接的多个工作电极，每个工作电极与参考电极组合形成换能器。 每个工作电极设置有由可电离部分和对化学和/或生物部分之一敏感的官能团组成的感测元件的涂层。

公开(公告)号：US20060146323A1

公开(公告)日：2006-07-06

申请号：US11030733

申请日：2005-01-06

Applicant: Alexandre Bratkovski ,  M. Islam ,  Theodore Kamins ,  Zhiyong Li ,  Shih-Yuan Wang

Inventor： Alexandre Bratkovski ,  M. Islam ,  Theodore Kamins ,  Zhiyong Li ,  Shih-Yuan Wang

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/658

Abstract: A SERS-active structure is disclosed that includes a substrate and at least two nanowires disposed on the substrate. Each of the at least two nanowires has a first end and a second end, the first end being attached to the substrate and the second end having a SERS-active tip. A SERS system is also disclosed that includes a SERS-active structure. Also disclosed are methods for forming a SERS-active structure and methods for performing SERS with SERS-active structures.

Abstract translation: 公开了一种SERS-活性结构，其包括衬底和设置在衬底上的至少两个纳米线。 所述至少两个纳米线中的每一个具有第一端和第二端，所述第一端附接到所述基底，所述第二端具有SERS活性末端。 还公开了包括SERS活性结构的SERS系统。 还公开了形成SERS活性结构的方法和用SERS活性结构进行SERS的方法。