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1.发明授权Methods of forming single-crystal metal-silicide nanowires and resulting nanowire structures 失效形成单晶金属硅化物纳米线和所得纳米线结构的方法公开(公告)号：US07829050B2
公开(公告)日：2010-11-09
申请号：US11707601
申请日：2007-02-13
Applicant: Zhaoning Yu , Zhiyong Li , Wei Wu , Shih-Yuan Wang , R. Stanley Williams
Inventor： Zhaoning Yu , Zhiyong Li , Wei Wu , Shih-Yuan Wang , R. Stanley Williams
IPC: C01B21/068
Abstract: Various embodiments of the present invention are directed to methods of forming single-crystal metal-silicide nanowires and resulting nanowire structures. In one embodiment of the present invention, a method of fabricating nanowires is disclosed. In the method, a number of nanowire-precursor members are formed. Each of the nanowire-precursor members includes a substantially single-crystal silicon region and a polycrystalline-metallic region. The substantially single-crystal silicon region and the polycrystalline-metallic region of each of the nanowire-precursor members is reacted to form corresponding substantially single-crystal metal-silicide nanowires. In another embodiment of the present invention, a nanowire structure is disclosed. The nanowire structure includes a substrate having an electrically insulating layer. A number of substantially single-crystal metal-silicide nanowires are positioned on the electrically insulating layer.
Abstract translation: 本发明的各种实施方案涉及形成单晶金属硅化物纳米线和所得纳米线结构的方法。 在本发明的一个实施例中，公开了一种制造纳米线的方法。 在该方法中，形成许多纳米线前体部件。 每个纳米线前体构件包括基本单晶硅区域和多晶金属区域。 每个纳米线前体部件的大致单晶硅区域和多晶金属区域反应形成对应的基本单晶金属硅化物纳米线。 在本发明的另一个实施方案中，公开了一种纳米线结构。 纳米线结构包括具有电绝缘层的衬底。 大量单晶金属硅化物纳米线位于电绝缘层上。
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2.发明授权Surface enhanced raman spectroscopy with periodically deformed SERS-active structure 有权具有周期性变形的SERS活性结构的表面增强拉曼光谱公开(公告)号：US07609377B2
公开(公告)日：2009-10-27
申请号：US11796455
申请日：2007-04-26
Applicant: Wei Wu , Zhiyong Li , Shih-Yuan Wang , Zhaoning Yu , R. Stanley Williams
Inventor： Wei Wu , Zhiyong Li , Shih-Yuan Wang , Zhaoning Yu , R. Stanley Williams
IPC: G01J3/44
CPC classification number: G01N21/658
Abstract: An apparatus and related methods for facilitating surface-enhanced Raman spectroscopy (SERS) is described. A SERS-active structure near which a plurality of analyte molecules is disposed is periodically deformed at an actuation frequency. A synchronous measuring device synchronized with the actuation frequency receives Raman radiation scattered from the analyte molecules and generates therefrom at least one Raman signal measurement.
Abstract translation: 描述了用于促进表面增强拉曼光谱（SERS）的装置和相关方法。 多个分析物分子附近的SERS-活性结构以致动频率周期性地变形。 与致动频率同步的同步测量装置接收从分析物分子散射的拉曼辐射，并由此产生至少一个拉曼信号测量。
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3.发明申请Methods of forming single-crystal metal-silicide nanowires and resulting nanowire structures 失效形成单晶金属硅化物纳米线和所得纳米线结构的方法公开(公告)号：US20080193359A1
公开(公告)日：2008-08-14
申请号：US11707601
申请日：2007-02-13
Applicant: Zhaoning Yu , Zhiyong Li , Wei Wu , Shih-Yuan Wang , R. Stanley Williams
Inventor： Zhaoning Yu , Zhiyong Li , Wei Wu , Shih-Yuan Wang , R. Stanley Williams
IPC: C01B21/068
Abstract: Various embodiments of the present invention are directed to methods of forming single-crystal metal-silicide nanowires and resulting nanowire structures. In one embodiment of the present invention, a method of fabricating nanowires is disclosed. In the method, a number of nanowire-precursor members are formed. Each of the nanowire-precursor members includes a substantially single-crystal silicon region and a polycrystalline- metallic region. The substantially single-crystal silicon region and the polycrystalline-metallic region of each of the nanowire-precursor members is reacted to form corresponding substantially single-crystal metal-silicide nanowires. In another embodiment of the present invention, a nanowire structure is disclosed. The nanowire structure includes a substrate having an electrically insulating layer. A number of substantially single-crystal metal-silicide nanowires are positioned on the electrically insulating layer.
Abstract translation: 本发明的各种实施方案涉及形成单晶金属硅化物纳米线和所得纳米线结构的方法。 在本发明的一个实施例中，公开了一种制造纳米线的方法。 在该方法中，形成许多纳米线前体部件。 每个纳米线前体构件包括大致单晶硅区域和多晶金属区域。 每个纳米线前体部件的大致单晶硅区域和多晶金属区域反应形成对应的基本单晶金属硅化物纳米线。 在本发明的另一个实施方案中，公开了一种纳米线结构。 纳米线结构包括具有电绝缘层的衬底。 大量单晶金属硅化物纳米线位于电绝缘层上。
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4.发明授权Nanoscale structures, systems, and methods for use in nano-enhanced raman spectroscopy (NERS) 有权用于纳米增强拉曼光谱（NERS）的纳米结构，系统和方法公开(公告)号：US07388661B2
公开(公告)日：2008-06-17
申请号：US11584446
申请日：2006-10-20
Applicant: Zhiyong Li , Zhaoning Yu
Inventor： Zhiyong Li , Zhaoning Yu
CPC classification number: G01J3/44 , B82Y15/00 , G01N21/658
Abstract: NERS-active structures for use in Raman spectroscopy include protrusions extending from a surface of a substrate. A Raman signal-enhancing material is disposed on at least one surface of a first protrusion and at least one surface of a second protrusion. The Raman signal-enhancing material disposed on the first protrusion projects laterally in a direction generally towards the second protrusion, and the Raman signal-enhancing material disposed on the second protrusion projects laterally in a direction generally towards the first protrusion. At least a portion of the Raman signal-enhancing projecting from the first protrusion and at least a portion of the Raman signal-enhancing material projecting from the second protrusion may be separated by a distance of less than about 10 nanometers. Raman spectroscopy systems include such NERS-active structures, and methods for performing Raman spectroscopy include irradiating an analyte proximate such a NERS-active structure and detecting Raman-scattered radiation scattered by the analyte.
Abstract translation: 用于拉曼光谱的NERS-活性结构包括从基底表面延伸的突起。 拉曼信号增强材料设置在第一突起的至少一个表面和第二突起的至少一个表面上。 设置在第一突起上的拉曼信号增强材料在大致朝向第二突起的方向上横向突出，并且设置在第二突起上的拉曼信号增强材料在大致朝向第一突起的方向上横向突出。 从第一突起突出的拉曼增强信号的至少一部分和从第二突起突出的拉曼增强材料的至少一部分可以分开小于约10纳米的距离。 拉曼光谱系统包括这样的NERS-活性结构，并且用于进行拉曼光谱的方法包括照射靠近这样的NERS-活性结构的分析物并检测被分析物散射的拉曼散射辐射。
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5.发明申请NANOSCALE STRUCTURES, SYSTEMS, AND METHODS FOR USE IN NANO-ENHANCED RAMAN SPECTROSCOPY (NERS) 有权在纳米增强拉曼光谱（NERS）中使用的纳米结构，系统和方法公开(公告)号：US20080094621A1
公开(公告)日：2008-04-24
申请号：US11584446
申请日：2006-10-20
Applicant: Zhiyong Li , Zhaoning Yu
Inventor： Zhiyong Li , Zhaoning Yu
CPC classification number: G01J3/44 , B82Y15/00 , G01N21/658
Abstract: NERS-active structures for use in Raman spectroscopy include protrusions extending from a surface of a substrate. A Raman signal-enhancing material is disposed on at least one surface of a first protrusion and at least one surface of a second protrusion. The Raman signal-enhancing material disposed on the first protrusion projects laterally in a direction generally towards the second protrusion, and the Raman signal-enhancing material disposed on the second protrusion projects laterally in a direction generally towards the first protrusion. At least a portion of the Raman signal-enhancing projecting from the first protrusion and at least a portion of the Raman signal-enhancing material projecting from the second protrusion may be separated by a distance of less than about 10 nanometers. Raman spectroscopy systems include such NERS-active structures, and methods for performing Raman spectroscopy include irradiating an analyte proximate such a NERS-active structure and detecting Raman-scattered radiation scattered by the analyte.
Abstract translation: 用于拉曼光谱的NERS-活性结构包括从基底表面延伸的突起。 拉曼信号增强材料设置在第一突起的至少一个表面和第二突起的至少一个表面上。 设置在第一突起上的拉曼信号增强材料在大致朝向第二突起的方向上横向突出，并且设置在第二突起上的拉曼信号增强材料在大致朝向第一突起的方向上横向突出。 从第一突起突出的拉曼增强信号的至少一部分和从第二突起突出的拉曼增强材料的至少一部分可以分开小于约10纳米的距离。 拉曼光谱系统包括这样的NERS-活性结构，并且用于进行拉曼光谱的方法包括照射靠近这样的NERS-活性结构的分析物并检测被分析物散射的拉曼散射辐射。
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Patent Agency Ranking
6.发明申请Surface enhanced raman spectroscopy with periodically deformed sers-active structure 有权表面增强拉曼光谱与周期性变形的主动结构公开(公告)号：US20080270042A1
公开(公告)日：2008-10-30
申请号：US11796455
申请日：2007-04-26
Applicant: Wei Wu , Zhiyong Li , Shih-Yuan Wang , Zhaoning Yu , R. Stanley Williams
Inventor： Wei Wu , Zhiyong Li , Shih-Yuan Wang , Zhaoning Yu , R. Stanley Williams
IPC: G01J3/44
CPC classification number: G01N21/658
Abstract: An apparatus and related methods for facilitating surface-enhanced Raman spectroscopy (SERS) is described. A SERS-active structure near which a plurality of analyte molecules is disposed is periodically deformed at an actuation frequency. A synchronous measuring device synchronized with the actuation frequency receives Raman radiation scattered from the analyte molecules and generates therefrom at least one Raman signal measurement.
Abstract translation: 描述了用于促进表面增强拉曼光谱（SERS）的装置和相关方法。 多个分析物分子附近的SERS-活性结构以致动频率周期性地变形。 与致动频率同步的同步测量装置接收从分析物分子散射的拉曼辐射，并由此产生至少一个拉曼信号测量。
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公开(公告)号：US10520440B2
公开(公告)日：2019-12-31
申请号：US14377524
申请日：2012-02-08
Applicant: Devin Alexander Mourey , James William Stasiak , James Elmer Abbott, Jr. , Zhiyong Li
Inventor： Devin Alexander Mourey , James William Stasiak , James Elmer Abbott, Jr. , Zhiyong Li
Abstract: Molecule sensing apparatus. The apparatus has first and second chambers, an input port extending into the first chamber, a fluid channel extending from the first chamber to the second chamber, and a surface-enhanced substrate in the second chamber.
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公开(公告)号：US09709538B2
公开(公告)日：2017-07-18
申请号：US14239330
申请日：2011-09-30
Applicant: Wei Wu , Zhiyong Li , Ansoon Kim , Min Hu , Michael Josef Stuke
Inventor： Wei Wu , Zhiyong Li , Ansoon Kim , Min Hu , Michael Josef Stuke
CPC classification number: G01N31/22 , B01L3/5085 , B01L3/50853 , B01L2200/141 , B01L2300/0636 , B01L2300/069 , B01L2300/0819 , B82Y15/00 , G01N21/648 , G01N21/658 , G01N2201/0227 , G01N2201/023 , Y10T436/25
Abstract: Devices to detect a substance and methods of producing such a device are disclosed. An example device to detect a substance includes a housing defining an externally accessible chamber and a seal to enclose at least a portion of the chamber. The example device also includes a substrate includes nanoparticles positioned within the chamber. The nanoparticles to react to the substance when exposed thereto. The example device also includes a non-analytic solution within the chamber to protect the nanoparticles from premature exposure.
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公开(公告)号：US09678013B2
公开(公告)日：2017-06-13
申请号：US14394295
申请日：2012-04-20
Applicant: Alexandre M. Bratkovski , Zhiyong Li , Wei Wu , Min Hu , R. Stanley Williams , Ansoon Kim
Inventor： Alexandre M. Bratkovski , Zhiyong Li , Wei Wu , Min Hu , R. Stanley Williams , Ansoon Kim
CPC classification number: G01N21/658 , B01L3/5088 , B01L2300/0627 , B01L2300/0819 , B01L2300/161 , G01N21/648 , G01N35/00009 , G01N2035/00019
Abstract: Examples of integrated sensors are disclosed herein. An example of an integrated sensor includes a substrate and a sensing member formed on a surface of the substrate. The sensing member includes collapsible signal amplifying structures and an area surrounding the collapsible signal amplifying structures that enables self-positioning of droplets exposed thereto toward the collapsible signal amplifying structures.
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公开(公告)号：US09592001B2
公开(公告)日：2017-03-14
申请号：US14406601
申请日：2012-07-29
Applicant: Steven Barcelo , Zhiyong Li , Ansoon Kim , Gary Gibson
Inventor： Steven Barcelo , Zhiyong Li , Ansoon Kim , Gary Gibson
IPC: G01J3/44 , A61B5/1459 , G01N21/65 , A61B5/00
CPC classification number: A61B5/1459 , A61B5/0075 , A61B5/6862 , G01N21/658
Abstract: An implantable nanosensor includes a stent to be implanted inside a fluid conduit. The stent has a well in a surface of the stent. The implantable nanosensor further includes a nanoscale-patterned sensing substrate disposed in the well. The nanoscale-patterned sensing substrate is to produce an optical scattering response signal indicative of a presence of an analyte in a fluid carried by the fluid conduit when interrogated by an optical stimulus signal.
Abstract translation: 可植入纳米传感器包括待植入流体导管内的支架。 支架在支架表面有一个井。 可植入纳米传感器还包括设置在井中的纳米级图案感测基片。 纳米级图案化感测衬底将产生光学散射响应信号，该信号指示由光学刺激信号询问时由流体导管携带的流体中分析物的存在。
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