公开(公告)号：US07799023B2

公开(公告)日：2010-09-21

申请号：US11534953

申请日：2006-09-25

Applicant: Brian K. Whisenant ,  Clark C. Davis ,  Daryl R. Edmiston

Inventor： Brian K. Whisenant ,  Clark C. Davis ,  Daryl R. Edmiston

IPC: A61B18/18

CPC classification number: A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2018/00214 ,  A61B2018/00351 ,  A61B2018/0063 ,  A61B2018/1435 ,  A61B2018/1467 ,  A61B2018/1475 ,  A61B2090/3966 ,  C08L2201/12

Abstract: A medical device for use in delivering RF energy to a tissue opening is disclosed. In one embodiment, the medical device comprises a compliant electrode. The compliant electrode can include a shape memory material, such as NITINOL, to facilitate the electrode having at least one relaxed orientation. The electrode can be deployed from a delivery shaft inside the left atrium, for example, of a heart through the delivery shaft. The electrode can be configured to substantially conform to the tissue proximate the tissue opening. After energy is applied to the tissue between the left and right electrodes, the left electrode can be removed from the left atrium by being received back into the delivery shaft and the delivery shaft thereafter removed from the opening.

Abstract translation: 公开了一种用于向组织开口输送RF能量的医疗装置。 在一个实施例中，医疗装置包括顺应性电极。 顺应性电极可以包括诸如NITINOL的形状记忆材料，以便于具有至少一个松弛取向的电极。 电极可以从左心房内的输送轴，例如通过输送轴的心脏部署。 电极可以构造成基本上符合组织开口附近的组织。 在将能量施加到左右电极之间的组织之后，左电极可以通过被收回到输送轴中而从左心房移除，此后从开口排出输送轴。

公开(公告)号：US20100191232A1

公开(公告)日：2010-07-29

申请号：US12694852

申请日：2010-01-27

Applicant: Serge Boveda

Inventor： Serge Boveda

IPC: A61B18/14 ,  A61B18/18

CPC classification number: A61B18/14 ,  A61B18/02 ,  A61B18/1206 ,  A61B18/1492 ,  A61B18/18 ,  A61B18/20 ,  A61B2017/00867 ,  A61B2018/00214 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00821 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1407 ,  A61B2218/002 ,  C08L2201/12

Abstract: An electrophysiological ablation catheter comprises a flexible shaft having a circumferential tissue ablation structure and a linear tissue ablation structure at its distal end. By positioning the circumferential tissue ablation structure in a pulmonary vein ostium and the linear tissue ablation structure extending radially from the pulmonary vein ostium toward a second pulmonary vein ostium, lesions around and between the ostium may be formed with a single catheter placement. Repositioning the catheter allows the remaining pulmonary vein ostia and tissue therebetween to be ablated in order to treat atrial fibrillation.

Abstract translation: 电生理消融导管包括在其远端具有周向组织消融结构和线性组织消融结构的柔性轴。 通过将周围组织消融结构定位在肺静脉口中，并且线性组织消融结构从肺静脉口向径向延伸到第二肺静脉口，可以用单个导管放置形成在口周围和之间的病变。 重新定位导管允许剩余的肺静脉口和其间的组织被烧蚀以便治疗心房颤动。

公开(公告)号：US07758510B2

公开(公告)日：2010-07-20

申请号：US11192749

申请日：2005-07-29

Applicant: Henry Nita ,  Martinos Tran

Inventor： Henry Nita ,  Martinos Tran

IPC: A61B8/14

CPC classification number: A61B17/320068 ,  A61B8/12 ,  A61B8/445 ,  A61B90/50 ,  A61B2017/00867 ,  C08L2201/12

Abstract: An ultrasound system has an ultrasound transducer having a transducer housing and a horn provided at the distal end of the transducer housing, an ultrasound transmission member, a sonic connector that is connected to the horn and the proximal end of the ultrasound transmission member, and a catheter knob having a proximal end that is coupled to the distal end of the transducer housing. The catheter knob has a proximal bore that houses the sonic connector. The system also includes a nesting piece that is retained inside the proximal bore of the catheter knob. The nesting piece can be moved from a first position where the sonic connector is received inside the nesting piece to a second position where the sonic connector is separated from the nesting piece when ultrasound energy is being propagated through the ultrasound transmission member.

Abstract translation: 超声波系统具有超声换能器，其具有设置在换能器壳体的远端的换能器壳体和喇叭，超声波传递部件，连接到喇叭和超声波传递部件的近端的声音连接器，以及 导管旋钮具有连接到换能器壳体的远端的近端。 导管旋钮具有容纳声音连接器的近端孔。 该系统还包括保留在导管旋钮的近端孔内的嵌套件。 嵌套件可以从声音连接器被接收在嵌套件内部的第一位置移动到第二位置，在第二位置，当超声波能量通过超声波传播构件传播时，声音连接器与嵌套件分离。

公开(公告)号：US20100168647A1

公开(公告)日：2010-07-01

申请号：US12345606

申请日：2008-12-29

Applicant: Troy T. Tegg ,  Richard E. Stehr

Inventor： Troy T. Tegg ,  Richard E. Stehr

IPC: A61M35/00 ,  A61M25/01

CPC classification number: A61B5/042 ,  A61B5/6858 ,  A61B18/1492 ,  A61B2017/00867 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00839 ,  A61B2090/065 ,  A61B2218/002 ,  C08L2201/12

Abstract: Catheter systems and methods are disclosed. An exemplary catheter includes an outer tubing housing and an inner fluid delivery tubing, the inner fluid delivery tubing having at least one fluid delivery port. The catheter also includes a deployment member movable axially within the inner fluid delivery tubing. A plurality of splines are each connected at a proximal end to the outer tubing and at a distal end to deployment member. A seal is provided between the outer tubing and the inner fluid delivery tubing. A gasket is provided between the deployment member and the inner fluid delivery tubing. Both the seal and the gasket are configured to prevent blood or other fluid from ingressing into the outer tubing.

Abstract translation: 公开了导管系统和方法。 示例性导管包括外管壳体和内流体输送管，内流体输送管具有至少一个流体输送端口。 导管还包括可在内部流体输送管内轴向移动的展开构件。 多个花键各自在近端连接到外管，并且在末端连接到展开构件。 在外管和内流体输送管之间提供密封。 在展开构件和内部流体输送管之间设置垫圈。 密封件和垫圈均被配置成防止血液或其他流体进入外管。

公开(公告)号：US20100106149A1

公开(公告)日：2010-04-29

申请号：US12522721

申请日：2008-01-11

Applicant: Nagy Habib

Inventor： Nagy Habib

IPC: A61B18/04

CPC classification number: A61B18/082 ,  A61B18/1492 ,  A61B2017/00867 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/1435 ,  A61B2018/1467 ,  A61B2018/1495 ,  C08L2201/12

Abstract: Devices suitable for insertion into a hollow anatomical structure within a patient for the purpose of ablating tissue within or surrounding the hollow structure so as to induce occlusion of the hollow structure are provided. The devices are in the form of guidewires with functional tips, that comprise at least one heating module, at their distal ends. The devices of the invention are suitable for occluding hollow anatomical structures selected from vasculature or from non-vascular ducts and tubes, via percutaneous, laparoscopic or endoscopic routes of access. Methods of using the devices in the treatment of patients are also described.

Abstract translation: 提供了适于插入到患者体内的中空解剖结构中的装置，用于在中空结构内或周围消融组织以引起中空结构的闭塞。 这些装置是具有功能尖端的导线的形式，其在其远端包括至少一个加热模块。 本发明的装置适合于通过经皮，腹腔镜或内窥镜进入途径闭塞从脉管系统或非血管导管和管中选择的中空解剖结构。 还描述了在患者治疗中使用该装置的方法。

公开(公告)号：US20090318312A1

公开(公告)日：2009-12-24

申请号：US12142791

申请日：2008-06-20

Applicant: Gregory John McAvoy ,  Emma Rose Kerr ,  Kia Silverbrook

Inventor： Gregory John McAvoy ,  Emma Rose Kerr ,  Kia Silverbrook

IPC: C40B60/00

CPC classification number: F04B43/043 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2300/0816 ,  B01L2400/0481 ,  B01L2400/0655 ,  C08L2201/12 ,  F16K99/0007 ,  F16K99/0015 ,  F16K99/0038 ,  F16K2099/008 ,  F16K2099/0084 ,  Y10T137/1624 ,  Y10T137/2224 ,  Y10T137/6606 ,  Y10T137/9138

Abstract: A microfluidic system. The system comprises: (A) a microfluidics platform comprising: a compliant body having a microfluidic channel defined therein; a valve sleeve defined by a section of the microfluidic channel, the valve sleeve having a membrane wall defining part of an outer surface of the body; and a compression member for pinching the membrane wall against an opposed wall of the valve sleeve; and (B) a MEMS integrated circuit bonded to the outer surface of the body, the MEMS integrated circuit comprising: a moveable finger engaged with the compression member, the finger being configured to urge the compression member between a closed position in which the membrane wall is sealingly pinched against the opposed wall, and an open position in which the membrane wall is disengaged from the opposed wall; a thermal bend actuator associated with the finger, the actuator configured for controlling movement of the finger; and control circuitry for controlling actuation of the actuator so as to control opening and closing of the valve sleeve.

Abstract translation: 微流体系统。 该系统包括：（A）微流体平台，包括：具有限定在其中的微流体通道的柔顺体; 由所述微流体通道的一部分限定的阀套，所述阀套具有限定所述主体的外表面的一部分的膜壁; 以及压缩构件，其用于将所述膜壁压靠在所述阀套的相对的壁上; 和（B）结合到所述主体的外表面的MEMS集成电路，所述MEMS集成电路包括：与所述压缩构件接合的可移动的手指，所述手指构造成将所述压缩构件推压在闭合位置，在所述闭合位置， 密封地夹在相对的壁上，以及打开位置，其中膜壁与相对的壁分离; 与手指相关联的热弯曲致动器，致动器构造成用于控制手指的移动; 以及用于控制致动器的致动以控制阀套的打开和关闭的控制电路。

公开(公告)号：US20090317302A1

公开(公告)日：2009-12-24

申请号：US12142784

申请日：2008-06-20

Applicant: Gregory John McAvoy ,  Emma Rose Kerr ,  Kia Silverbrook

Inventor： Gregory John McAvoy ,  Emma Rose Kerr ,  Kia Silverbrook

IPC: B81B7/02 ,  B81B3/00 ,  F04B43/08 ,  F04B43/12 ,  B01L3/00

CPC classification number: B41J2/1623 ,  B01L3/502707 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2200/10 ,  B01L2200/12 ,  B01L2300/087 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2300/14 ,  B01L2400/0481 ,  B01L2400/0655 ,  B01L2400/082 ,  B41J2/14427 ,  B41J2/1631 ,  B41J2/1645 ,  C08L2201/12 ,  F04B19/006 ,  F04B43/043 ,  F16K99/0001 ,  F16K99/0007 ,  F16K99/0038 ,  F16K2099/0084 ,  Y10T137/0318 ,  Y10T137/0396 ,  Y10T137/2213

Abstract: A microfluidic system comprising a MEMS integrated circuit. The MEMS integrated circuit comprises: a silicon substrate having one or more microfluidic channels defined therein; at least one layer of control circuitry for controlling one or more microfluidic devices; a MEMS layer comprising the microfluidic devices; and a polymeric layer covering the MEMS layer. Part of the polymeric layer provides a seal for the microfluidic devices.

Abstract translation: 一种包括MEMS集成电路的微流体系统。 MEMS集成电路包括：具有限定在其中的一个或多个微流体通道的硅衬底; 用于控制一个或多个微流体装置的至少一层控制电路; 包括微流体装置的MEMS层; 以及覆盖MEMS层的聚合物层。 聚合物层的一部分为微流体装置提供密封。

公开(公告)号：US20090254019A1

公开(公告)日：2009-10-08

申请号：US12304440

申请日：2007-06-12

Applicant: Karen Julie Gehl ,  Karsten Videbaek

Inventor： Karen Julie Gehl ,  Karsten Videbaek

IPC: A61N1/30

CPC classification number: A61N1/327 ,  A61B18/1477 ,  A61B2017/00867 ,  A61B2018/00083 ,  A61B2018/00613 ,  A61B2018/143 ,  A61B2018/1475 ,  A61B2018/1495 ,  A61B2218/002 ,  A61N1/05 ,  A61N1/0502 ,  C08L2201/12

Abstract: An electroporation device 1 comprising a handle section 100; an elongate introducer shaft 10 connected to said handle section 100, said introducer shaft 10 having a distal tip 13; and a set of electrodes 60 having respective distal ends 61, each electrode 60 being slidably arranged within said introducer shaft 10 from a retracted position, where said distal ends 61 are enclosed within said introducer shaft 10, to an exposed position, where said distal ends 61 extend from said distal tip 13; wherein said electrode distal ends 61 are deflectable away from a longitudinal axis L of said shaft 10 when deployed/extended to their extended position, such that at least one planar projection taken in a plane perpendicular to said longitudinal axis L of distance D1 between a pair of distal ends 61 of said electrodes 60 is larger than a maximal extent D2 of a cross-section of said introducer shaft 10, said cross-section taken in a plane perpendicular to said longitudinal axis L at a distal end 11 of said introducer shaft 10.

Abstract translation: 电穿孔装置1，包括手柄部分100; 连接到所述手柄部分100的细长引导器轴10，所述导引轴10具有远端尖端13; 以及具有各自的远端61的一组电极60，每个电极60从所述远端61被封闭在所述引导器轴10内的缩回位置可滑动地布置在所述引导器轴10内的暴露位置处，其中所述远端 61从所述远端13延伸; 其中当展开/延伸到其延伸位置时，所述电极远端61可以偏离所述轴10的纵向轴线L，使得至少一个平面突起在垂直于一对之间的距离D1的所述纵向轴线L的平面 所述电极60的远端61大于所述引导器轴10的横截面的最大范围D2，所述横截面在与所述纵向轴线L垂直的平面中在所述导引轴10的远端11处 。

公开(公告)号：US20090209975A1

公开(公告)日：2009-08-20

申请号：US11922656

申请日：2006-06-23

Applicant: Zoran Milijasevic ,  Norman Booth

Inventor： Zoran Milijasevic ,  Norman Booth

IPC: A61B18/18

CPC classification number: A61M25/0136 ,  A61B18/1492 ,  A61B2017/00867 ,  A61B2018/1407 ,  C08L2201/12

Abstract: A catheter assembly (10) includes a handle body (12) having a proximal end (14) and a distal end. An introducer carrier (18) is displaceably arranged relative to the handle body (12). An electrode sheath component is arranged at a distal end of the handle body (12), the electrode sheath component comprising at least one pair of limbs interconnected by a bridging portion, at least the bridging portion carrying at least one electrode. An elongate shape forming component (40) is received in a lumen of the electrode sheath component, the shape forming component (40) having at least one predetermined shape formed along its length. An introducer component (22) is carried on the introducer carrier (18) of the handle body (12). The electrode sheath component is received within the introducer component (22) prior to use with at least the bridging portion of the electrode sheath component being extended out of a distal end of the introducer component (22) to be exposed for use. The arrangement is such that movement between at least two of the components relative to each other results in a change of shape being imparted to the exposed bridging portion of the electrode sheath component.

Abstract translation: 导管组件（10）包括具有近端（14）和远端的把手主体（12）。 引导器托架（18）相对于把手主体（12）可移位地布置。 电极护套部件布置在手柄本体（12）的远端处，电极护套部件包括至少一对通过桥接部分互连的肢体，至少桥接部分承载至少一个电极。 细长成形部件（40）被容纳在电极护套部件的内腔中，成形部件（40）具有沿着其长度形成的至少一个预定形状。 引导器部件（22）被承载在手柄主体（12）的引导器托架（18）上。 所述电极鞘组件在使用之前被容纳在所述导引器部件（22）内，并且至少所述电极护套部件的所述桥接部分从所述导引器部件（22）的远端延伸出以供使用。 该布置使得至少两个部件之间相对于彼此的运动导致赋予电极护套部件的暴露的桥接部分的形状变化。

公开(公告)号：US20090192510A1

公开(公告)日：2009-07-30

申请号：US12356650

申请日：2009-01-21

Applicant: Timothy J. Bahney

Inventor： Timothy J. Bahney

IPC: A61B18/14

CPC classification number: A61B18/1482 ,  A61B17/221 ,  A61B17/32056 ,  A61B18/10 ,  A61B18/1492 ,  A61B2017/00269 ,  A61B2017/00287 ,  A61B2017/00353 ,  A61B2017/00867 ,  A61B2018/00601 ,  A61B2018/00642 ,  A61B2018/1407 ,  A61B2018/141 ,  A61B2018/144 ,  A61F2002/30095 ,  A61F2210/0023 ,  C08L2201/12

Abstract: An endoscopic electrosurgical instrument is presented for encapsulating and resecting biologic tissue, such as a polyp, from an anatomical structure, such as a lumen. The instrument includes an encapsulation assembly which includes a snare coupled to an electrically non-conductive, shrinkable pouch in a drawstring-like configuration. The encapsulation assembly may be folded within the elongated cylindrical housing of the endoscopic instrument, positioned within the patient at the surgical site, and deployed for use. Once positioned over the polyp, the snare is tightened around the peduncle thereof, and the pouch is activated, thereby shrinking and encapsulating the polyp. The polyp may then be resected using conventional or electrosurgical techniques. The disclosed instrument may include surgical tools and/or electrosurgical electrodes for performing surgical procedures. The disclosed system may reduce the occurrence of undesirable arcing and may aid retrieval of resected tissue.

Abstract translation: 提供内窥镜电外科手术器械用于从诸如内腔的解剖结构包封和切除生物组织，例如息肉。 仪器包括封装组件，其包括以束带状构造耦合到不导电，可收缩的小袋的圈套。 封装组件可以折叠在内窥镜器械的细长圆柱形壳体内，定位在患者体内的外科手术部位，并被部署使用。 一旦定位在息肉上方，圈套围绕其束缚，并且袋被活化，从而收缩并包封息肉。 然后可以使用常规或电外科技术切除息肉。 所公开的仪器可以包括用于执行外科手术的手术工具和/或电外科电极。 所公开的系统可以减少不期望的电弧放电的发生并且可以帮助检索被切除的组织。