ANALYTE SENSOR
    222.
    发明申请

    公开(公告)号:US20140046148A1

    公开(公告)日:2014-02-13

    申请号:US14057720

    申请日:2013-10-18

    Applicant: DexCom, Inc.

    Abstract: Devices and methods are provided for continuous measurement of an analyte concentration. The device can include a sensor having a plurality of sensor elements, each having at least one characteristic that is different from other sensor(s) of the device. In some embodiments, the plurality of sensor elements are each tuned to measure a different range of analyte concentration, thereby providing the device with the capability of achieving a substantially consistent level of measurement accuracy across a physiologically relevant range. In other embodiments, the device includes a plurality of sensor elements each tuned to measure during different time periods after insertion or implantation, thereby providing the sensor with the capability to continuously and accurately measure analyte concentrations across a wide range of time periods. For example, a sensor system 180 is provided having a first working electrode 150 comprising a first sensor element 102 and a second working electrode 160 comprising a second sensor element 104, and a reference electrode 108 for providing a reference value for measuring the working electrode potential of the sensor elements 102, 104.

    ELECTRODE SYSTEMS FOR ELECTROCHEMICAL SENSORS
    223.
    发明申请
    ELECTRODE SYSTEMS FOR ELECTROCHEMICAL SENSORS 审中-公开
    电化学传感器电极系统

    公开(公告)号:US20140001042A1

    公开(公告)日:2014-01-02

    申请号:US14014216

    申请日:2013-08-29

    Applicant: DexCom, Inc.

    CPC classification number: G01N27/3274 A61B5/14532 A61B5/14865 C12Q1/001

    Abstract: The present invention relates generally to systems and methods for improved electrochemical measurement of analytes. The preferred embodiments employ electrode systems including an analyte-measuring electrode for measuring the analyte or the product of an enzyme reaction with the analyte and an auxiliary electrode configured to generate oxygen and/or reduce electrochemical interferants. Oxygen generation by the auxiliary electrode advantageously improves oxygen availability to the enzyme and/or counter electrode; thereby enabling the electrochemical sensors of the preferred embodiments to function even during ischemic conditions. Interferant modification by the auxiliary electrode advantageously renders them substantially non-reactive at the analyte-measuring electrode, thereby reducing or eliminating inaccuracies in the analyte signal due to electrochemical interferants.

    Abstract translation: 本发明一般涉及用于改进分析物的电化学测量的系统和方法。 优选实施例采用电极系统,包括用于测量被分析物的分析物测量电极或与分析物的酶反应的产物以及被配置为产生氧和/或减少电化学干扰剂的辅助电极。 通过辅助电极产生氧气有利地提高了对酶和/或对电极的氧气可利用性; 从而使得优选实施例的电化学传感器能够在缺血状况下起作用。 通过辅助电极的干扰修饰有利地使得它们在分析物 - 测量电极处基本上不反应,从而减少或消除由于电化学干扰剂引起的分析物信号的不准确性。

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