公开(公告)号：US20120253840A1

公开(公告)日：2012-10-04

申请号：US13505103

申请日：2010-10-25

Applicant: Glen H. Murata

Inventor： Glen H. Murata

IPC: G06Q50/22

CPC classification number: G06F19/3468 ,  A61M5/1723 ,  G06Q10/04 ,  G06Q50/22 ,  G16H50/30

Abstract: A system and method for estimating HbA1c, diabetic patient treatment response and hypoglycemia risk using data obtained from patient self-monitoring of blood glucose. The system includes a computer having a processor, data storage, display, and data input ports. The data storage stores an insulin manager module that has instructions performed by the processor when self-monitoring of blood glucose (SMBD) data is provided to the computer via one of the data input ports. The processor uses the SMBD data to generate reports displaying estimated HbAIc and other factors effecting blood glucose levels in a diabetic patient and prescribes insulin treatment plans.

Abstract translation: 使用从患者自我监测血糖获得的数据估计HbA1c，糖尿病患者治疗反应和低血糖风险的系统和方法。 该系统包括具有处理器，数据存储，显示和数据输入端口的计算机。 数据存储器存储胰岛素管理器模块，其具有由处理器执行的指令，当通过数据输入端口之一向计算机提供血糖（SMBD）数据的自我监测时。 处理器使用SMBD数据生成报告，显示估计的HbAIc和影响糖尿病患者血糖水平的其他因素，并规定了胰岛素治疗计划。

公开(公告)号：US08277872B1

公开(公告)日：2012-10-02

申请号：US12617617

申请日：2009-11-12

Applicant: Marwan S. Al-Haik ,  Jonathan Phillips ,  Claudia Luhrs ,  Mahmoud Reda Taha

Inventor： Marwan S. Al-Haik ,  Jonathan Phillips ,  Claudia Luhrs ,  Mahmoud Reda Taha

IPC: C23C16/06 ,  C23C16/26

CPC classification number: C23C16/26 ,  B82Y30/00 ,  B82Y40/00 ,  C01B32/15 ,  C01B32/16 ,  C23C16/0281 ,  C23C18/08 ,  D01F9/127 ,  D01F9/14 ,  D06M11/74 ,  D06M2101/28 ,  D06M2101/40

Abstract: Methods of manufacturing a carbon structure including exposing a carbon fiber substrate to oxygen at a first predetermined temperature and activating the carbon fiber substrate by exposure to oxygen at a second predetermined temperature. A catalyst including palladium is deposited on the activated carbon fiber substrate. The deposited catalyst on the carbon fiber structure is exposed to a hydrocarbon at a third predetermined temperature to grow carbon structures thereon. The carbon structures grown can be multimodal in nature with structures that are nano-scale and/or submicron-scale.

Abstract translation: 制造碳结构体的方法，包括在第一预定温度下将碳纤维基材暴露于氧并通过在第二预定温度下暴露于氧来活化碳纤维基材。 包含钯的催化剂沉积在活性碳纤维基材上。 将碳纤维结构上沉积的催化剂暴露于第三预定温度下的烃，以在其上生长碳结构。 生长的碳结构本质上可以是具有纳米尺度和/或亚微米尺度的结构的多峰。

公开(公告)号：US08257685B2

公开(公告)日：2012-09-04

申请号：US11732489

申请日：2007-04-03

Applicant: Hugh D. Smyth ,  Martin J. Donovan

Inventor： Hugh D. Smyth ,  Martin J. Donovan

IPC: A61K9/00 ,  A61K9/12 ,  A61K9/14

CPC classification number: A61K9/0073 ,  A61K9/0075 ,  A61K9/0078 ,  A61K9/1641 ,  A61K47/60 ,  A61K47/6949 ,  A61K48/00 ,  B82Y5/00 ,  Y10T428/2982

Abstract: Swellable particles for delivery of a drug or other working agent to the pulmonary system are provided. The swellable particles include a dehydrated (dry) aerodynamic particle diameter of 5 μm or less to enable delivery to the respiratory tract, such as for example to the tracheo-bronchial airways of the upper respiratory tract and/or to the alveolic regions of the deep lung, and a hydrated particle diameter that is greater than 6 μm volume mean diameter to retard or prevent their phagocytosis by the macrophages present in airways of the respiratory tract.

Abstract translation: 提供了用于将药物或其它工作剂递送至肺部系统的可溶胀颗粒。 可溶胀颗粒包括5μm或更小的脱水（干燥）空气动力学粒径，以使得能够输送到呼吸道，例如向上呼吸道的气管支气管气道和/或深层的通气区域 肺，以及大于6μm体积平均直径的水合颗粒直径，以阻止或阻止其由呼吸道气道中的巨噬细胞吞噬。

公开(公告)号：US08252711B1

公开(公告)日：2012-08-28

申请号：US12709618

申请日：2010-02-22

Applicant: Tim Olson ,  Plamen Atanassov

Inventor： Tim Olson ,  Plamen Atanassov

IPC: B01J31/00 ,  C07D487/22 ,  C07B47/00 ,  B05D5/12

CPC classification number: B01J31/06 ,  B01J31/183 ,  B01J2531/025 ,  B01J2531/845 ,  C07D487/22 ,  H01M4/9008 ,  H01M4/9091

Abstract: A highly dispersed, unsupported, electrocatalyst made of pyrolyzed porphyries and a method for synthesizing the same. The disclosed synthesis procedure allows for optimization of pore size and therefore transport properties. Compounds suitable for use include transition metal N4-chelates such as, but not necessarily limited to, N4-chelates containing different metal centers including Co, Fe, Mn, Ni, Ru, Cu, etc., and other N4-chelates such as porphyrin, phthalocyanies, and structures based on their pyro products.

Abstract translation: 由热解斑斑形成的高度分散，无支撑的电催化剂及其合成方法。 所公开的合成方法允许优化孔径并因此优化输送性质。 适合使用的化合物包括过渡金属N 4 - 螯合物，例如但不一定限于含有不同金属中心的包括Co，Fe，Mn，Ni，Ru，Cu等的N 4 - 螯合物和其它N 4 - 螯合物如卟啉 ，酞菁，以及基于其产品的结构。

公开(公告)号：US08246933B2

公开(公告)日：2012-08-21

申请号：US12324318

申请日：2008-11-26

Applicant: Xingmao Jiang ,  C. Jeffrey Brinker ,  Yong Lin ,  Yung-Sung Cheng

Inventor： Xingmao Jiang ,  C. Jeffrey Brinker ,  Yong Lin ,  Yung-Sung Cheng

IPC: A61K9/14 ,  A01N59/16

CPC classification number: A61K33/38 ,  A01N59/16 ,  A61K9/5115 ,  A61K9/5192 ,  A01N25/06 ,  A01N25/34 ,  A01N2300/00

Abstract: A method of forming and resulting nano-structured composite includes atomizing a mixture of an amount of each of aminopropyltriethoxysilane, AgNO3, DI water, and ethanol in a carrier gas; heating the atomized droplets at a selected temperature for a time sufficient to reduce the Ag to its elemental form in a silica matrix; and outputting the nano structured composite particles. A predetermined heating time is from about 0.01 to about 40 seconds and a selected heating temperature is from about 200 to about 800° C. The nano structured composite includes a plurality of nano particles at a contact surface of the composite, dispersed throughout and at a contact surface of the composite, or dispersed throughout the composite.

Abstract translation: 形成和得到的纳米结构复合材料的方法包括在载气中雾化一定量的氨基丙基三乙氧基硅烷，AgNO 3，去离子水和乙醇的混合物; 在所选择的温度下加热雾化的液滴足以将Ag还原成二氧化硅基质中其元素的时间; 并输出纳米结构复合颗粒。 预定的加热时间为约0.01至约40秒，选定的加热温度为约200至约800℃。纳米结构复合材料包括在复合材料的接触表面处的多个纳米颗粒，分散在整个和 复合材料的接触表面，或分散在整个复合材料中。

公开(公告)号：US20120197104A1

公开(公告)日：2012-08-02

申请号：US13322332

申请日：2010-10-24

Applicant: Stefan Posse ,  Andre Van Der Kouwe ,  Kunxiu Gao ,  Weili Zheng

Inventor： Stefan Posse ,  Andre Van Der Kouwe ,  Kunxiu Gao ,  Weili Zheng

IPC: A61B5/055

CPC classification number: G01R33/4838 ,  G01R33/4833 ,  G01R33/4835 ,  G01R33/5607

Abstract: A system and methods for imaging a patient organ. The system includes a MRI imaging apparatus communicating with a memory and processor. The method aligns the organ with a standardized organ, and includes a step of spatially normalizing the standardized organ to the patient organ. The method also provides optimized slices of the standardized organ and translates optimized slices of standardized organ into optimized slices of the patient organ. The method images the patient organ according to the optimized slices of the patient organ.

Abstract translation: 用于成像患者器官的系统和方法。 该系统包括与存储器和处理器通信的MRI成像设备。 该方法使器官与标准化器官对齐，并且包括将标准化器官空间归一化到患者器官的步骤。 该方法还提供了标准化器官的优化切片，并将优化的标准化器官切片转化为患者器官的优化切片。 该方法根据患者器官的优化切片对患者器官进行成像。

公开(公告)号：US08208724B2

公开(公告)日：2012-06-26

申请号：US13118165

申请日：2011-05-27

Applicant: Ousseini Lankoande ,  Majeed M. Hayat ,  Balu Santhanam

Inventor： Ousseini Lankoande ,  Majeed M. Hayat ,  Balu Santhanam

IPC: G06K9/34 ,  G06K9/62

CPC classification number: G06K9/0063 ,  G06K9/40 ,  G06K9/4638 ,  G06T5/002 ,  G06T2207/10132 ,  G06T2207/20012

Abstract: The present invention includes methods for the reduction of speckle noise in an image and methods for segmenting an image. Each of the methods disclosed herein includes steps for analyzing the uniformity of a pixel within a plurality of pixels forming a portion of the image and, based on the uniformity of the intensity of the plurality of pixels, adjusting and/or replacing the pixel in order to produce a speckle-noise reduced image, a segmented image, or a segmented and speckle-noise reduced image. The methods of the present invention can employ for example conditional probability density functions, nonlinear estimator functions, convex energy functions and simulated annealing algorithms in the performance of their respective steps.

Abstract translation: 本发明包括用于减少图像中的斑点噪声的方法和用于分割图像的方法。 本文公开的每种方法包括用于分析形成图像的一部分的多个像素内的像素的均匀性的步骤，并且基于多个像素的强度的均匀性，按顺序调整和/或替换像素 以产生斑点噪声缩小图像，分割图像或分割和斑点噪声缩小图像。 本发明的方法可以在其各自的步骤的执行中使用例如条件概率密度函数，非线性估计函数，凸能量函数和模拟退火算法。

公开(公告)号：US08188513B2

公开(公告)日：2012-05-29

申请号：US12246044

申请日：2008-10-06

Applicant: Stephen D. Hersee ,  Xin Wang

Inventor： Stephen D. Hersee ,  Xin Wang

IPC: H01L29/66

CPC classification number: H01L29/0665 ,  B82Y10/00 ,  H01L21/02389 ,  H01L21/02458 ,  H01L21/02513 ,  H01L21/0254 ,  H01L21/02603 ,  H01L21/0262 ,  H01L21/02639 ,  H01L21/8252 ,  H01L27/0605 ,  H01L29/2003 ,  H01L29/66462 ,  H01L29/7787 ,  H01L29/7788 ,  H01L29/7789

Abstract: Nanowire and larger, post-based HEMTs, arrays of such HEMTs, and methods for their manufacture are provided. In one embodiment, a HEMT can include a III-N based core-shell structure including a core member (e.g., GaN), a shell member (e.g., AlGaN) surrounding a length of the core member and a two-dimensional electron gas (2-DEG) at the interface therebetween. The core member including a nanowire and/or a post can be disposed over a doped buffer layer and a gate material can be disposed around a portion of the shell member. Exemplary methods for making the nanowire HEMTs and arrays of nanowire HEMTs can include epitaxially forming nanowire(s) and epitaxially forming a shell member from each formed nanowire. Exemplary methods for making the post HEMTs and arrays of post HEMTs can include etching a III-N layer to form III-N post(s) followed by formation of the shell member(s).

Abstract translation: 提供了纳米线和更大的后置HEMT，这样的HEMT的阵列及其制造方法。 在一个实施例中，HEMT可以包括基于III-N的核 - 壳结构，其包括芯构件（例如，GaN），围绕芯构件的长度的壳构件（例如，AlGaN）和二维电子气 2-DEG）。 包括纳米线和/或柱的芯构件可以设置在掺杂缓冲层上方，并且栅极材料可以围绕壳构件的一部分设置。 用于制造纳米线HEMT和纳米线HEMT阵列的示例性方法可以包括外延形成纳米线并从每个形成的纳米线外延地形成壳部件。 用于制造后HEMT和后HEMT阵列的示例性方法可以包括蚀刻III-N层以形成III-N柱，随后形成壳构件。

公开(公告)号：US20120082286A1

公开(公告)日：2012-04-05

申请号：US13278315

申请日：2011-10-21

Applicant: Mohamed S. El-Genk ,  Jean-Michel P. Tournier

Inventor： Mohamed S. El-Genk ,  Jean-Michel P. Tournier

IPC: G21C15/00

CPC classification number: F28D15/0233 ,  F28D15/0266 ,  F28D15/0275 ,  F28D15/04 ,  F28D2021/0054

Abstract: Methods and apparatuses are provided for the removal and transportation of thermal energy from a heat source to a distant complex for use in thermochemical cycles or other processes. In one embodiment, an apparatus includes a hybrid heat pipes/thermosyphon intermediate heat exchanger (HPTIHX) system that is divided into three distinct sections, namely: an evaporation chamber, a condensation chamber, and a working fluid transport section of liquid and vapor counter-current flows.

Abstract translation: 提供了用于将热能从热源移除到远离的复合物以用于热化学循环或其它工艺中的方法和装置。 在一个实施例中，一种装置包括分为三个不同部分的混合热管/热虹吸中间热交换器（HPTIHX）系统，即：蒸发室，冷凝室和液体和蒸汽反应器的工作流体输送部分， 电流。

公开(公告)号：US20120070372A1

公开(公告)日：2012-03-22

申请号：US13309972

申请日：2011-12-02

Applicant: Jeffrey P. Norenberg ,  Richard S. Larson

Inventor： Jeffrey P. Norenberg ,  Richard S. Larson

IPC: A61K51/04 ,  C07F9/94 ,  A61P29/00 ,  A61P37/00 ,  A61P9/10 ,  A61P9/00 ,  A61P13/12 ,  A61P19/02 ,  A61P17/00 ,  A61P7/00 ,  A61P1/00 ,  A61P37/06 ,  A61P35/00 ,  A61P35/04 ,  A61P11/00 ,  A61P25/00 ,  A61P3/10 ,  A61P27/02 ,  A61P17/06 ,  A61P17/12 ,  A61P35/02 ,  C07F5/00

CPC classification number: C07F5/003 ,  A61K47/22 ,  A61K49/106 ,  A61K51/0474 ,  A61K51/0482 ,  A61K51/0485 ,  A61K51/0497 ,  C07F9/94

Abstract: The present invention is directed to novel non-invasive diagnostic tools to image cancers, especially, leukemia and non-Hodgkin's lymphomas (NHL) with minimal toxicity in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probe is capable of detecting precancerous cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and staging of NHL using non-invasively molecular imaging techniques. This novel probe will also be useful to monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of NHL. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.

Abstract translation: 本发明涉及用于对癌症特别是白血病和非霍奇金淋巴瘤（NHL）进行成像的新型非侵入性诊断工具，其体内毒性最小。 本发明代表了目前依赖于组织活检以诊断这些癌症的本领域的明显进步。 该新型成像探针能够检测癌前细胞，以及它们在组织中的转移扩散。 这代表了使用非侵入性分子成像技术在NHL的诊断和分期中向前推进的量子进程。 该新型探针也可用于监测患者对化疗治疗的反应和用于治疗NHL的其他干预措施或疗法。 根据本发明的化合物可以用作许多病症和疾病状态的诊断工具以及用于治疗这些病症和疾病状态的治疗剂。