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公开(公告)号：US20190242794A1
公开(公告)日：2019-08-08
申请号：US16367791
申请日：2019-03-28
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Hershel Macaulay
Abstract: Among other things, a diluted sample is generated based on mixing a small sample of blood with a one or more diluents. A thin film of the diluted sample is formed on the surface of a contact optical microscopy sensor. Red blood cells within a portion of the thin film of the diluted sample are illuminated using light of a predetermined wavelength. One or more images of the diluted sample are acquired based on illuminating the red blood cells within the portion of the thin film of the diluted sample. The acquired one or more images of the diluted sample are then processed. The mean corpuscular hemoglobin in the red blood cells within the portion of the thin film of the diluted sample is determined based on processing the acquired images of the diluted sample.
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公开(公告)号：US10317662B2
公开(公告)日：2019-06-11
申请号：US15482215
申请日：2017-04-07
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine
IPC: G02B21/36 , G01N33/49 , G01N1/38 , G01N21/31 , G01N1/28 , B01L3/00 , G01N15/06 , G01N15/00 , B01L3/02 , G01N1/40 , G01N15/14 , G01N35/10
Abstract: In some instances, an apparatus can include a light sensitive imaging sensor having a surface to receive a fluid sample, a body to be moved relative to the light sensitive imaging sensor and having a surface to touch a portion of the fluid sample, and a carrier to move the body toward the surface of the light sensitive imaging sensor to cause the surface of the body to touch the portion of the fluid sample, so that as the surface of the body touches the portion of the fluid, the surface of the body (i) is parallel to the surface of the light sensitive imaging sensor, and (ii) settles on top of the fluid sample independently of motion of the carrier.
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公开(公告)号：US10153317B1
公开(公告)日：2018-12-11
申请号：US15963894
申请日：2018-04-26
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Madhuranga Srinath Rankaduwa
IPC: H01L27/146 , G01N21/27 , G01N33/49
Abstract: Among other things, an integral image sensor includes a sensor surface having a surface area at which light-sensitive pixels are arranged in rows and columns. The surface area includes two or more light-sensitive subareas each of the subareas having been configured to have been diced from a wafer along two orthogonal dimensions to form a discrete image sensor. The two or more light-sensitive subareas are arranged along one of the two orthogonal dimensions. The sensor surface of the integral image sensor is flat and continuous across the two or more subareas.
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公开(公告)号：US20170322402A1
公开(公告)日：2017-11-09
申请号：US15642434
申请日：2017-07-06
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Peter Hodges Gregson
IPC: G02B21/00
CPC classification number: G02B21/0008
Abstract: Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.
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公开(公告)号：US20170075099A1
公开(公告)日：2017-03-16
申请号：US15360724
申请日：2016-11-23
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Hershel Macaulay , Noah Hymes-Vandermeulen
CPC classification number: G02B21/34 , G01N1/28 , G01N1/4077 , G01N15/0606 , G01N15/0612 , G01N15/1468 , G01N21/59 , G01N33/49 , G01N35/00029 , G01N2015/008 , G01N2015/1087 , G01N2015/1486
Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.
Abstract translation: 除其他之外，第一表面被配置为接收样品并且用于显微镜装置。 存在相对于第一表面移动到预定位置的第二表面以形成位于第一表面和第二表面之间并且包含至少部分样品的样品空间。 存在被配置为将第二表面从初始位置移动到预定位置以形成样本空间的机构。 当样品在第一表面上就位时，第二表面的运动包括不仅仅是第二表面朝向第一表面的线性运动的轨迹。
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Patent Agency Ranking
公开(公告)号：US12174358B2
公开(公告)日：2024-12-24
申请号：US17931414
申请日：2022-09-12
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Joel Ironstone , Christopher Gillespie
Abstract: A base assembly includes an imaging sensor having a sensor surface to receive a sample, and a platform connected to the base assembly. The base assembly includes (a) an aperture configured to receive a lid surface of a lid in a position to define an imaging space between the sensor surface and the lid surface and (b) a movement portion movable toward and away from the base assembly. The platform and the base assembly are configured to limit contact between the sample and the base assembly other than at the sensor surface.
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公开(公告)号：US11947096B2
公开(公告)日：2024-04-02
申请号：US17712959
申请日：2022-04-04
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Peter Hodges Gregson
IPC: G02B21/00
CPC classification number: G02B21/0008
Abstract: Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.
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公开(公告)号：US11719700B2
公开(公告)日：2023-08-08
申请号：US17349682
申请日：2021-06-16
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine
IPC: G01N33/58 , G01N33/50 , G01N21/77 , G01N33/53 , G01N33/543 , G01N33/569
CPC classification number: G01N33/585 , G01N21/77 , G01N33/5094 , G01N33/5302 , G01N33/543 , G01N33/54366 , G01N33/56983 , G01N33/587 , G01N33/588
Abstract: Two or more upconverting particles are attached to each unit of one or more units of a chemical component in a sample, to form, for each unit of the chemical component, a multi-particle complex including the unit of the chemical component and two or more corresponding upconverting particles. The sample is illuminated by input light having a first wavelength. Light is received at an imaging sensor, the received light including output light generated by at least a portion of the upconverting particles attached to the units of the chemical component, the output light having a second wavelength that is shorter than the first wavelength. One or more images of the sample are captured from the received light. Based on the captured one or more images, a presence or a level of the chemical component in the sample is determined.
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公开(公告)号：US20230110857A1
公开(公告)日：2023-04-13
申请号：US17931414
申请日：2022-09-12
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Joel Ironstone , Christopher Gillespie
Abstract: A base assembly includes an imaging sensor having a sensor surface to receive a sample, and a platform connected to the base assembly. The base assembly includes (a) an aperture configured to receive a lid surface of a lid in a position to define an imaging space between the sensor surface and the lid surface and (b) a movement portion movable toward and away from the base assembly. The platform and the base assembly are configured to limit contact between the sample and the base assembly other than at the sensor surface.
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公开(公告)号：US20220206282A1
公开(公告)日：2022-06-30
申请号：US17696704
申请日：2022-03-16
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Hershel Macaulay , Noah Hymes-Vandermeulen
Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.
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