公开(公告)号：US20140371622A1

公开(公告)日：2014-12-18

申请号：US14473221

申请日：2014-08-29

申请人： Michael R. Hausman ,  Geoffrey B. Thrope ,  Robert B. Strother ,  Joseph J. Mrva

发明人： Michael R. Hausman ,  Geoffrey B. Thrope ,  Robert B. Strother ,  Joseph J. Mrva

IPC分类号： A61B5/00 ,  A61N1/36 ,  A61N1/04

CPC分类号： A61B5/4893 ,  A61B5/05 ,  A61B5/4519 ,  A61B5/4523 ,  A61B5/4836 ,  A61B17/1626 ,  A61B17/8875 ,  A61B18/1477 ,  A61B90/04 ,  A61B2018/00601 ,  A61B2018/1412 ,  A61N1/0456 ,  A61N1/36014

摘要： Systems and methods according to the present invention provide a means for determining, as an example, the health or location of nerves. Generally, embodiments according to the present invention may be used to verify the absence of nerve tissue along a prospective incision location to avoid damage caused by such incision. Alternatively or additionally, embodiments according to the present invention may be used to locate and/or hone in on a more precise location of one or more nerves. Electrical stimulation may be applied to tissue in an iterative fashion in one or more desired patterns and at one or more stimulation intensities to determine one or more regional neural responses and one or more focused neural responses.

摘要翻译： 根据本发明的系统和方法提供了用于确定神经的健康或位置作为示例的手段。 通常，根据本发明的实施例可以用于验证沿着预期切口位置的神经组织的不存在，以避免由这种切口引起的损伤。 或者或另外，根据本发明的实施例可以用于定位和/或磨削在一个或多个神经的更精确的位置。 电刺激可以以一种或多种所需模式和一种或多种刺激强度以迭代方式施用于组织以确定一个或多个区域神经反应和一个或多个聚焦神经反应。

公开(公告)号：US08805533B2

公开(公告)日：2014-08-12

申请号：US13031482

申请日：2011-02-21

申请人： Joseph W. Boggs, II ,  Geoffrey B. Thrope ,  Robert B. Strother ,  Joseph J. Mrva

发明人： Joseph W. Boggs, II ,  Geoffrey B. Thrope ,  Robert B. Strother ,  Joseph J. Mrva

IPC分类号： A61N1/36

CPC分类号： A61N1/05 ,  A61M2205/054 ,  A61M2210/1067 ,  A61M2210/1089 ,  A61N1/0512 ,  A61N1/0524 ,  A61N1/36007 ,  A61N1/36107

摘要： Systems and methods use an external and/or implantable pulse generator system for neuromodulation stimulation to treat sexual dysfunction by the unilateral or bilateral stimulation of a target nerve A and/or a target nerve B using one or more leads and electrodes implanted in tissue in the pelvic region. The electrical stimulation waveform may be conveyed to the target nerve A electrode for a first predetermined amount of time, and conveyed to the target nerve B electrode for a second predetermined amount of time.

摘要翻译： 系统和方法使用外部和/或可植入的脉冲发生器系统进行神经调节刺激，以通过使用植入组织中的一个或多个引线和电极单目或双侧刺激靶神经A和/或靶神经B来治疗性功能障碍 骨盆部位。 电刺激波形可以以第一预定量的时间传送到目标神经A电极，并且传送到目标神经B电极第二预定时间量。

公开(公告)号：US20140058495A1

公开(公告)日：2014-02-27

申请号：US13913798

申请日：2013-06-10

申请人： Johnathan L. Sakai ,  Maria E. Bennett ,  Joseph W. Boggs, III ,  Robert B. Strother ,  Geoffrey B. Thrope ,  Kenneth P. Rundle ,  Stuart F. Rubin

发明人： Johnathan L. Sakai ,  Maria E. Bennett ,  Joseph W. Boggs, III ,  Robert B. Strother ,  Geoffrey B. Thrope ,  Kenneth P. Rundle ,  Stuart F. Rubin

IPC分类号： A61N1/04

CPC分类号： A61N1/0496 ,  A61N1/0551 ,  A61N1/36003 ,  A61N1/36017 ,  A61N1/36021

摘要： Neurostimulation assemblies, systems, and methods make possible the providing of short-term therapy or diagnostic testing by providing electrical connections between muscles and/or nerves inside the body and stimulus generators and/or recording instruments mounted on the surface of the skin or carried outside the body. Neurostimulation assemblies, systems, and methods may include a carrier and an electronics pod, the electronics pod including stimulation generation circuitry and user interface components. A power source and/or flash memory may be incorporated in neurostimulation assembly and/or the return electrode. The assemblies, systems, and methods are adapted to provide coordinated neurostimulation to multiple regions of the body.

摘要翻译： 神经刺激组件，系统和方法可以通过提供身体内的肌肉和/或神经之间的电连接，以及安装在皮肤表面上或外部携带的刺激发生器和/或记录仪器来提供短期治疗或诊断测试 身体。 神经刺激组件，系统和方法可以包括载体和电子舱，电子舱包括刺激产生电路和用户界面组件。 电源和/或闪存可以并入神经刺激组件和/或返回电极中。 组件，系统和方法适于为身体的多个区域提供协调的神经刺激。

公开(公告)号：US20120238902A1

公开(公告)日：2012-09-20

申请号：US13466485

申请日：2012-05-08

申请人： ROBERT B. STROTHER ,  Geoffrey B. Thrope ,  Joseph J. Mrva ,  Steven M. Galecki ,  Danny R. Pack ,  Christopher A. Thierfelder ,  James Coburn

发明人： ROBERT B. STROTHER ,  Geoffrey B. Thrope ,  Joseph J. Mrva ,  Steven M. Galecki ,  Danny R. Pack ,  Christopher A. Thierfelder ,  James Coburn

IPC分类号： A61B5/05

CPC分类号： A61B5/04001 ,  A61B5/4893 ,  A61B17/1626 ,  A61B17/8875 ,  A61B18/1402 ,  A61B90/04 ,  A61B2017/00022 ,  A61B2017/00154 ,  A61N1/36014

摘要： Improved assemblies, systems, and methods provide safeguarding against tissue injury during surgical procedures and/or identify nerve damage occurring prior to surgery and/or verify range of motion or attributes of muscle contraction during reconstructive surgery. A stimulation control device may incorporate a range of low and high intensity stimulation to provide a stimulation and evaluation of both nerves and muscles. A stimulation control device is removably coupled to a surgical device or is imbedded within the medical device to provide a stimulation and treatment medical device. A disposable hand held stimulation system includes an operative element extending from the housing, the housing includes a visual indication to provide feedback or status to the user.

摘要翻译： 改进的组件，系统和方法提供了在手术过程中的组织损伤的保护和/或识别在手术之前发生的神经损伤和/或验证重建手术期间肌肉收缩的运动范围或属性。 刺激控制装置可以包括一系列低和高强度刺激，以提供对神经和肌肉的刺激和评估。 刺激控制装置可拆卸地联接到手术装置或嵌入在医疗装置内以提供刺激和治疗医疗装置。 一次性手持刺激系统包括从壳体延伸的操作元件，壳体包括用于向使用者提供反馈或状态的可视指示。

公开(公告)号：US08086318B2

公开(公告)日：2011-12-27

申请号：US11595556

申请日：2006-11-10

申请人： Robert B. Strother ,  Geoffrey B. Thrope ,  Steven M. Galecki ,  Joseph J. Mrva ,  Danny R. Pack

发明人： Robert B. Strother ,  Geoffrey B. Thrope ,  Steven M. Galecki ,  Joseph J. Mrva ,  Danny R. Pack

IPC分类号： A61N1/18

CPC分类号： A61N1/36017 ,  A61H39/002 ,  A61N1/0456 ,  A61N1/0492 ,  A61N1/0529 ,  A61N1/0551 ,  A61N1/36003 ,  A61N1/36014 ,  A61N1/36021 ,  A61N1/37247 ,  A61N1/375 ,  A61N1/378 ,  H01M2/105 ,  H01M2/1061

摘要： Neurostimulation assemblies, systems, and methods make possible the providing of short-term therapy or diagnostic testing by providing electrical connections between muscles or nerves inside the body and stimulus generators or recording instruments mounted on the surface of the skin or carried outside the body. Neurostimulation assemblies, systems, and methods may include a carrier and a removable electronics pod, the electronics pod including stimulation generation circuitry, a power input bay to hold a disposable power source, and user interface components. The assemblies, systems, and methods are adapted to provide coordinated neurostimulation to multiple regions of the body.

摘要翻译： 神经刺激组件，系统和方法可以通过提供身体内的肌肉或神经之间的电连接，以及安装在皮肤表面上或携带在身体外部的刺激发生器或记录仪器来提供短期治疗或诊断测试。 神经刺激组件，系统和方法可以包括载体和可拆卸的电子舱，电子舱包括刺激产生电路，用于保持一次性电源的电力输入舱和用户接口部件。 组件，系统和方法适于为身体的多个区域提供协调的神经刺激。

公开(公告)号：US20110060238A1

公开(公告)日：2011-03-10

申请号：US12806691

申请日：2010-08-19

申请人： MICHAEL R. HAUSMAN ,  GEOFFREY B. THROPE ,  ROBERT B. STROTHER ,  JOSEPH J. MRVA

发明人： MICHAEL R. HAUSMAN ,  GEOFFREY B. THROPE ,  ROBERT B. STROTHER ,  JOSEPH J. MRVA

IPC分类号： A61B5/04

CPC分类号： A61B5/05 ,  A61B5/4519 ,  A61B5/4523 ,  A61B5/4893 ,  A61B17/1626 ,  A61B17/8875 ,  A61B18/1477 ,  A61B90/04 ,  A61B2018/00601 ,  A61B2018/1412 ,  A61N1/36014

摘要： Improved assemblies, systems, and methods provide safeguarding against tissue injury during surgical procedures and/or identify nerve damage occurring prior to surgery and/or verify range of motion or attributes of muscle contraction during reconstructive surgery. Embodiments of methods according to the present invention provide the ability to intra-operatively simulate post-operative physiologic function of a body part. Such methods may be used during various surgical procedures, including tendon transfer procedures. Included are one or more steps of confirming paralysis or a weakened condition of a body part, confirming responsivity or operability of transfer tissue to supplement the functionality of the paralyzed or weakened part, and intra-operatively simulating post-operative functionality of the transfer tissue to enhance and/or predict the outcome of the surgical procedure.

摘要翻译： 改进的组件，系统和方法提供了在手术过程中的组织损伤的保护和/或识别在手术之前发生的神经损伤和/或验证重建手术期间肌肉收缩的运动范围或属性。 根据本发明的方法的实施例提供了在手术中模拟身体部位的手术后生理功能的能力。 这种方法可以在各种手术过程中使用，包括肌腱转移程序。 包括确认瘫痪或身体部位状况变弱的一个或多个步骤，确认传递组织的补偿性或麻痹部分的功能性的反应性或可操作性，以及术中模拟转移组织的术后功能 增强和/或预测外科手术的结果。

公开(公告)号：US20100274324A1

公开(公告)日：2010-10-28

申请号：US12829187

申请日：2010-07-01

申请人： Maria E. Bennett ,  Kenneth P. Rundle ,  Stuart F. Rubin ,  James Coburn ,  Danny R. Pack ,  Robert B. Strother ,  Geoffrey B. Thrope ,  Joseph J. Mrva

发明人： Maria E. Bennett ,  Kenneth P. Rundle ,  Stuart F. Rubin ,  James Coburn ,  Danny R. Pack ,  Robert B. Strother ,  Geoffrey B. Thrope ,  Joseph J. Mrva

IPC分类号： A61N1/08

CPC分类号： A61N1/37217 ,  A61N1/37247

摘要： Systems and methods for programming and logging medical device and patient data are provided. The systems include a handheld device, which is capable of communicating with a medical device, and a base station, which provides connectivity for the handheld device to accomplish various functions such as recharging, programming, data back-up and data entry. The methods comprise the steps of detecting a medical device, obtaining and recording information from the medical device. Additionally, medical device parameters may be modified and the recorded information may be archived for future reference.

摘要翻译： 提供了用于编程和记录医疗设备和患者数据的系统和方法。 该系统包括能够与医疗设备进行通信的手持设备以及为手持设备提供连接以完成各种功能（例如充电，编程，数据备份和数据输入）的基站。 所述方法包括检测医疗装置，从医疗装置获取和记录信息的步骤。 此外，医疗设备参数可以被修改，并且记录的信息可以存档以备将来参考。

公开(公告)号：US20100036445A1

公开(公告)日：2010-02-11

申请号：US12462384

申请日：2009-08-03

申请人： Johnathan L. Sakai ,  Maria E. Bennett ,  Joseph W. Boggs, II ,  Robert B. Strother ,  Geoffrey B. Thrope ,  Kenneth P. Rundle ,  Stuart F. Rubin

发明人： Johnathan L. Sakai ,  Maria E. Bennett ,  Joseph W. Boggs, II ,  Robert B. Strother ,  Geoffrey B. Thrope ,  Kenneth P. Rundle ,  Stuart F. Rubin

IPC分类号： A61N1/00 ,  A61N1/05

CPC分类号： A61N1/0496 ,  A61N1/0551 ,  A61N1/36003 ,  A61N1/36017 ,  A61N1/36021

摘要： Neurostimulation assemblies, systems, and methods make possible the providing of short-term therapy or diagnostic testing by providing electrical connections between muscles and/or nerves inside the body and stimulus generators and/or recording instruments mounted on the surface of the skin or carried outside the body. Neurostimulation assemblies, systems, and methods may include a carrier and an electronics pod, the electronics pod including stimulation generation circuitry and user interface components. A power source and/or flash memory may be incorporated in neurostimulation assembly and/or the return electrode. The assemblies, systems, and methods are adapted to provide coordinated neurostimulation to multiple regions of the body.

摘要翻译： 神经刺激组件，系统和方法可以通过提供身体内的肌肉和/或神经之间的电连接，以及安装在皮肤表面上或外部携带的刺激发生器和/或记录仪器来提供短期治疗或诊断测试 身体。 神经刺激组件，系统和方法可以包括载体和电子舱，电子舱包括刺激产生电路和用户界面组件。 电源和/或闪存可以并入神经刺激组件和/或返回电极中。 组件，系统和方法适于为身体的多个区域提供协调的神经刺激。

公开(公告)号：US20080132969A1

公开(公告)日：2008-06-05

申请号：US11981113

申请日：2007-10-31

申请人： Maria E. Bennett ,  Julie Grill ,  Tina E. Lechman ,  Joseph J. Mrva ,  Jonathan L. Sakai ,  Robert B. Strother ,  Geoffrey B. Thrope ,  Therese M. Zmina

发明人： Maria E. Bennett ,  Julie Grill ,  Tina E. Lechman ,  Joseph J. Mrva ,  Jonathan L. Sakai ,  Robert B. Strother ,  Geoffrey B. Thrope ,  Therese M. Zmina

IPC分类号： A61N1/05

CPC分类号： A61N1/372 ,  A61N1/0521 ,  A61N1/0558 ,  A61N1/36007 ,  A61N1/36017 ,  A61N1/36107

摘要： Systems and methods treat urologic dysfunctions by implanting a lead and electrode in a tissue region affecting urologic function, and coupling the lead to an external pulse generator. If desired results are achieved, the external pulse generator is removed and an implantable pulse generator is implanted in an anterior pelvic region remote from the electrode. Bilateral stimulation of the left and/or right branches of the dorsal genital nerves using a single lead implanted in adipose or other tissue in the region at or near the pubic symphysis is able to treat urologic dysfunctions.

摘要翻译： 系统和方法通过将铅和电极植入影响泌尿功能的组织区域来治疗泌尿系统功能障碍，并将引线耦合到外部脉冲发生器。 如果达到期望的结果，则移除外部脉冲发生器，将植入式脉冲发生器植入远离电极的前部骨盆区域。 使用植入在耻骨联合或其附近区域的脂肪或其他组织中的单个导线来双侧刺激背生殖神经的左侧和/或右侧分支能够治疗泌尿功能障碍。

公开(公告)号：US07343202B2

公开(公告)日：2008-03-11

申请号：US11150419

申请日：2005-06-10

申请人： Joseph J. Mrva ,  Robert B. Strother ,  Geoffrey B. Thrope ,  Julie Grill ,  Maria Bennett

发明人： Joseph J. Mrva ,  Robert B. Strother ,  Geoffrey B. Thrope ,  Julie Grill ,  Maria Bennett

IPC分类号： A61N1/36

CPC分类号： A61N1/36007 ,  A61N1/05 ,  A61N1/0524 ,  A61N1/0551 ,  A61N1/0558 ,  A61N1/372

摘要： Systems and methods provide a stimulation electrode assembly comprising an elongated lead sized and configured to be implanted within an adipose tissue region. The lead includes an electrically conductive portion to apply electrical stimulation to nerve or muscle in the adipose tissue region and at least one expandable anchoring structure deployable from the lead to engage adipose tissue and resist dislodgment and/or migration of the electrically conductive portion within the adipose tissue region.

摘要翻译： 系统和方法提供了一种刺激电极组件，其包括尺寸和构造成植入脂肪组织区域内的细长导线。 引线包括导电部分，以对脂肪组织区域中的神经或肌肉施加电刺激，以及至少一个可展开的锚定结构，其可从导线部署以接合脂肪组织并抵抗脂肪内的导电部分的移动和/或迁移 组织区域。