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    Microarraying process and apparatus
    21.
    发明授权
    Microarraying process and apparatus 有权
    微阵列工艺和设备

    公开(公告)号：US07208124B2

    公开(公告)日：2007-04-24

    申请号：US10298948

    申请日：2002-11-19

    Applicant: David Elverd ,  James Keith Haslam ,  Trevor Ruddock

    Inventor： David Elverd ,  James Keith Haslam ,  Trevor Ruddock

    IPC: B01N3/02 ,  G01N1/10

    CPC classification number: B01L3/0244 ,  B01J2219/00387 ,  B01J2219/00691 ,  B01L9/547 ,  B01L99/00 ,  B01L2200/04 ,  C12M33/04 ,  C40B60/14 ,  G01N35/0099 ,  G01N2035/1076 ,  Y10T436/2575

    Abstract: A high throughput microarraying or colony picking robot with an automatic mechanism for exchanging pin heads and an automated washing and drying apparatus. The robot allows a dirty pin head to be deposited on the automated washing and drying apparatus for cleaning without use of the xyz-positioner, while spotting or picking can continue by picking up a clean pin head without having to wait for the dirty pin head to be cleaned. In this way, the speed of operation can be increased without any increase in the acceleration or speed of the x-, y- and z-drives. The dead time normally associated with the washing and drying cycle, which is usually several minutes, is therefore eliminated, and replaced with the much shorter dead time, of only a few tens of seconds, needed for changing between heads.

    Abstract translation: 具有用于更换针头的自动机构和自动洗涤和干燥装置的高通量微阵列或集落拾取机器人。 机器人可以将脏针头沉积在自动洗涤和干燥设备上，无需使用xyz定位器进行清洁，同时通过拾取干净的针头可以继续点样或拾取，而无需等待脏针头 被清理 以这种方式，可以在不增加x，y和z驱动器的加速度或速度的情况下提高运行速度。 因此，通常与洗涤和干燥循环相关联的通常几分钟的死区时间被消除，并且被更换为头部之间需要更短的几十秒的死区时间。

    Polymer particles having select pendant groups and composition prepared therefrom
    22.
    发明授权
    Polymer particles having select pendant groups and composition prepared therefrom 有权
    具有选择侧基的聚合物颗粒和由其制备的组合物

    公开(公告)号：US07179531B2

    公开(公告)日：2007-02-20

    申请号：US10642791

    申请日：2003-08-18

    Applicant: Ward Thomas Brown ,  James Keith Bardman

    Inventor： Ward Thomas Brown ,  James Keith Bardman

    IPC: B32B5/16

    CPC classification number: C08F2/001 ,  C01P2004/88 ,  C08F230/02 ,  C08F265/04 ,  C08F265/06 ,  C08F275/00 ,  C08K9/08 ,  C09C1/3684 ,  C09C1/3692 ,  C09D151/00 ,  C09D151/003 ,  Y10T428/2982 ,  Y10T428/2998 ,  C08F220/10

    Abstract: Polymer particles having select functional or absorbing groups are provided. The polymer particles are useful for preparing organic-inorganic composite particles that are suitable for providing dried coatings with improved hiding. Aqueous compositions containing these composite particles are also provided. The select absorbing groups include phosphorus acid groups, phosphorus acid full-ester groups, polyacid sidechain groups, and salts thereof. The select functional groups are capable of forming covalently bonded composite particles. The composite particles formed from the multistage polymer particles having the select functional or absorbing groups are useful for preparing dried coatings with a combination of improved hiding, increased gloss, and good film properties.

    Abstract translation: 提供具有选择的功能或吸收基团的聚合物颗粒。 聚合物颗粒可用于制备适于提供具有改进的遮盖性的干燥涂层的有机 - 无机复合颗粒。 还提供含有这些复合颗粒的含水组合物。 选择性吸收基团包括磷酸基，磷酸全酯基，多酸侧链基团及其盐。 选择的官能团能够形成共价键合的复合颗粒。 由具有选择性功能或吸收基团的多级聚合物颗粒形成的复合颗粒可用于制备干燥涂层，其组合具有改善的遮盖性，增加的光泽度和良好的膜性能。

    Topical formulation for delivery of interleukin-11
    25.
    发明申请
    Topical formulation for delivery of interleukin-11 审中-公开
    用于递送白细胞介素-11的局部制剂

    公开(公告)号：US20050129658A1

    公开(公告)日：2005-06-16

    申请号：US11050246

    申请日：2005-02-03

    Applicant: Nick Warne ,  Camille Bedrosian ,  James Keith ,  Ullrich Schwertschlag ,  Paul Schendel

    Inventor： Nick Warne ,  Camille Bedrosian ,  James Keith ,  Ullrich Schwertschlag ,  Paul Schendel

    IPC: A61K38/00 ,  A61K38/19 ,  A61K38/20

    CPC classification number: A61K38/2073 ,  A61K9/0031 ,  A61K9/0056 ,  A61K9/006

    Abstract: Provided by the present invention are topical formulations of Interleukin-11 and methods for treating a variety of disorders, including inflammatory bowel diseases (e.g., Crohn's disease, ulcerative colitis, indeterminate colitis, and infectious colitis), mucositis (e.g., oral mucositis, gastrointestinal mucositis, nasal mucositis, and proctitis), necrotizing enterocolitis, inflammatory skin disorders (e.g., psoriasis, atopic dermatitis, and contact hypersensitivity), aphthous ulcers, pharyngitis, esophagitis, peptic ulcers, gingivitis, periodontitis, and ocular diseases (e.g., conjunctivitis, retinitis, and uveitis).

    Abstract translation: 本发明提供了白介素-11的局部制剂和用于治疗各种疾病的方法，包括炎症性肠病（例如克罗恩病，溃疡性结肠炎，不确定性结肠炎和感染性结肠炎），粘膜炎（例如口腔粘膜炎，胃肠道 肠粘膜炎和直肠炎），坏死性小肠结肠炎，炎性皮肤病（例如银屑病，特应性皮炎和接触性超敏反应），口疮性溃疡，咽炎，食管炎，消化性溃疡，牙龈炎，牙周炎和眼部疾病（例如结膜炎， 视网膜炎和葡萄膜炎）。

    Arm rest mouse pad
    26.
    发明授权
    Arm rest mouse pad 失效
    扶手鼠标垫

    公开(公告)号：US06352303B1

    公开(公告)日：2002-03-05

    申请号：US08938844

    申请日：1997-09-26

    Applicant: James Keith Hope

    Inventor： James Keith Hope

    IPC: A47C768

    CPC classification number: A47C7/68 ,  Y10S248/918

    Abstract: A removable computer mouse and pad support platform attachable to either one of a chair's armrests. The platform has a main support portion for the mouse/pad and an extension arm extending therefrom parallel to the armrests. To attached the platform to one of the armrests, the platform extension arm is oriented parallel to the chair's armrest and one wide strap or two spaced straps are used to encircle and fix it around the armrest. The strap or straps may have hook and loop (VELCRO™) ends or the like which acts as end fasteners. When not made as in the preferred unitary structure embodiment, the two piece main support platform and its lower extension arm may be attached together with screws, bonding material or other fasteners.

    Abstract translation: 一个可移动的电脑鼠标和垫支撑平台可连接到椅子的扶手之一。 平台具有用于鼠标/垫的主支撑部分和从平行于扶手延伸的延伸臂。 为了将平台连接到其中一个扶手上，平台延伸臂平行于椅子的扶手定向，并且使用一个宽带或两个间隔的带围绕并固定在扶手周围。 带子或带子可以具有作为端部紧固件的钩和环（VELCRO TM）端部等。 当不如在优选的单一结构实施例中制造时，两件式主支撑平台及其下延伸臂可以用螺钉，接合材料或其它紧固件附接在一起。

    Fluid film bearings
    27.
    发明授权
    Fluid film bearings 失效
    流体膜轴承

    公开(公告)号：US5772334A

    公开(公告)日：1998-06-30

    申请号：US732269

    申请日：1996-10-25

    Applicant: David Walter Parkins ,  James Keith Martin

    Inventor： David Walter Parkins ,  James Keith Martin

    IPC: F16C17/03 ,  F16C17/06 ,  F16C25/02 ,  F16C33/10 ,  F16C32/06

    CPC classification number: F16C17/035 ,  F16C17/065 ,  F16C25/02 ,  F16C33/106 ,  F16C23/02

    Abstract: A hydrodynamic fluid film bearing in which a plurality of circumferentially spaced bearing elements are provided, defining areas of support for the rotating part of the bearing. At least some of the bearing elements are adjustable during operation to vary lubrication conditions in the fluid film. The bearing elements are of sufficiently high stiffness that the position of the entire bearing surface of each element is essentially independent of the pressure in the fluid film encountered during operation. The bearing allows complete control of the lubrication conditions and can be adjusted for optimum performance over a wide range of speed and load.

    Abstract translation: PCT No.PCT / GB95 / 00955 371日期1996年10月25日第 102（e）日期1996年10月25日PCT提交1995年4月26日PCT公布。 WO95 / 29346 PCT公开号 日期1995年1月21日一种流体动力流体膜轴承，其中设置有多个周向间隔开的轴承元件，限定了用于轴承的旋转部分的支撑区域。 至少一些轴承元件在操作期间是可调节的，以改变流体膜中的润滑条件。 轴承元件具有足够高的刚度，使得每个元件的整个支承表面的位置基本上与操作期间遇到的流体膜中的压力无关。 轴承允许完全控制润滑条件，并可在宽范围的速度和负载下进行最佳性能调整。

    Automatic gain control circuit for a crystal oscillator
    29.
    发明授权
    Automatic gain control circuit for a crystal oscillator 失效
    晶体振荡器的自动增益控制电路

    公开(公告)号：US3982210A

    公开(公告)日：1976-09-21

    申请号：US624617

    申请日：1975-10-22

    Applicant: James Keith Gehrke

    Inventor： James Keith Gehrke

    IPC: H03B5/36 ,  H03L5/00 ,  H03B3/02

    CPC classification number: H03L5/00 ,  H03B5/362 ,  H03B2200/0008

    Abstract: A single bipolar transistor crystal oscillator with the bias on the base of the transistor fixed and a second transistor coupled in parallel with the transistor of the oscillator for providing an alternate current path when the second transistor is conducting to reduce the current gain of the oscillator transistor, and a diode connected to the base of the second transistor for rectifying the AC output signals of the oscillator and biasing the second transistor into conduction when the output of the oscillator exceeds a predetermined value.

    Abstract translation: 一个双极晶体管晶体振荡器，其晶体管的基极上具有偏置，而第二晶体管与振荡器的晶体管并联耦合，以在第二晶体管导通时提供交流电流路径，以减小振荡晶体管的电流增益 以及连接到第二晶体管的基极的二极管，用于在振荡器的输出超过预定值时对振荡器的AC输出信号进行整流，并将第二晶体管偏置为导通。

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