公开(公告)号：US06994827B2

公开(公告)日：2006-02-07

申请号：US09873176

申请日：2001-06-01

申请人： Adam Safir ,  Ralph Nielsen ,  Thomas H. McWaid ,  Richard Tiede ,  Lynn Van Erden

发明人： Adam Safir ,  Ralph Nielsen ,  Thomas H. McWaid ,  Richard Tiede ,  Lynn Van Erden

IPC分类号： G01N33/00 ,  B01N3/02 ,  B01N3/00 ,  B01J10/00 ,  B32B27/04

CPC分类号： B01F7/167 ,  B01F7/00258 ,  B01F7/00266 ,  B01F7/00291 ,  B01F7/00416 ,  B01F7/00575 ,  B01F15/00207 ,  B01F2215/0037 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00308 ,  B01J2219/00335 ,  B01J2219/00337 ,  B01J2219/00342 ,  B01J2219/00353 ,  B01J2219/00373 ,  B01J2219/00389 ,  B01J2219/00418 ,  B01J2219/00477 ,  B01J2219/00481 ,  B01J2219/00495 ,  B01J2219/00585 ,  B01J2219/00601 ,  B01J2219/00689 ,  B01J2219/00698 ,  B01J2219/00722 ,  C40B40/14 ,  C40B60/14 ,  G01N35/1079

摘要： Parallel semi-continuous or continuous reactors are disclosed. The parallel reactors preferably comprise four or more reaction vessels. The reaction vessels are preferably small volume reaction vessels, preferably pressure reaction vessels, and/or preferably integral with a common reactor block. The reaction vessels can comprise shaft-driven stirrers. At least two, preferably at least three or at least four liquid feed lines can provide selective fluid communication between each of the reaction vessels and one or more liquid reagent sources. Additional features, suitable in connection with parallel reactors or with single reaction vessels are also disclosed.

公开(公告)号：US07208124B2

公开(公告)日：2007-04-24

申请号：US10298948

申请日：2002-11-19

申请人： David Elverd ,  James Keith Haslam ,  Trevor Ruddock

发明人： David Elverd ,  James Keith Haslam ,  Trevor Ruddock

IPC分类号： B01N3/02 ,  G01N1/10

CPC分类号： B01L3/0244 ,  B01J2219/00387 ,  B01J2219/00691 ,  B01L9/547 ,  B01L99/00 ,  B01L2200/04 ,  C12M33/04 ,  C40B60/14 ,  G01N35/0099 ,  G01N2035/1076 ,  Y10T436/2575

摘要： A high throughput microarraying or colony picking robot with an automatic mechanism for exchanging pin heads and an automated washing and drying apparatus. The robot allows a dirty pin head to be deposited on the automated washing and drying apparatus for cleaning without use of the xyz-positioner, while spotting or picking can continue by picking up a clean pin head without having to wait for the dirty pin head to be cleaned. In this way, the speed of operation can be increased without any increase in the acceleration or speed of the x-, y- and z-drives. The dead time normally associated with the washing and drying cycle, which is usually several minutes, is therefore eliminated, and replaced with the much shorter dead time, of only a few tens of seconds, needed for changing between heads.

摘要翻译： 具有用于更换针头的自动机构和自动洗涤和干燥装置的高通量微阵列或集落拾取机器人。 机器人可以将脏针头沉积在自动洗涤和干燥设备上，无需使用xyz定位器进行清洁，同时通过拾取干净的针头可以继续点样或拾取，而无需等待脏针头 被清理 以这种方式，可以在不增加x，y和z驱动器的加速度或速度的情况下提高运行速度。 因此，通常与洗涤和干燥循环相关联的通常几分钟的死区时间被消除，并且被更换为头部之间需要更短的几十秒的死区时间。

公开(公告)号：US06924152B2

公开(公告)日：2005-08-02

申请号：US10103992

申请日：2002-03-25

申请人： Shigeki Matsubara ,  Kyoko Imai ,  Ryuji Tao

发明人： Shigeki Matsubara ,  Kyoko Imai ,  Ryuji Tao

IPC分类号： G01N35/00 ,  G01N35/02 ,  G01N35/10 ,  G01N1/10 ,  G01N35/08 ,  B01N3/02

CPC分类号： G01N35/026 ,  G01N35/00603 ,  G01N35/02 ,  G01N35/025 ,  G01N35/1009 ,  G01N35/1065 ,  G01N35/1083 ,  G01N2035/00326 ,  G01N2035/103 ,  G01N2035/1076 ,  G01N2035/1086 ,  Y10T436/11 ,  Y10T436/112499 ,  Y10T436/113332 ,  Y10T436/114165 ,  Y10T436/114998 ,  Y10T436/12 ,  Y10T436/2575

摘要： Sample sampling to an analysis apparatus 200 or 820 for analyzing a biochemical analysis item is performed by a pipetting device 202 or 840 which uses a repetitively used pipette nozzle, and sample sampling to an analysis apparatus 100 or 810 for analyzing an immune analysis item is performed by a pipetting device 102 or 830 which uses a disposable nozzle tip. A sample bottle containing a sample to be analyzed on both of a biochemical analysis item and an immune analysis item is sample-pipetted by the nozzle tip first, and then transported so as to be sample-pipetted by the pipette nozzle.