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    Microfabricated microscope assembly
    21.
    发明授权
    Microfabricated microscope assembly 失效
    微型显微镜组件

    公开(公告)号：US5015850A

    公开(公告)日：1991-05-14

    申请号：US368664

    申请日：1989-06-20

    申请人： Mark J. Zdeblick ,  Thomas R. Albrecht

    发明人： Mark J. Zdeblick ,  Thomas R. Albrecht

    IPC分类号： G01B7/34 ,  B81B3/00 ,  G01B7/00 ,  G01B21/30 ,  G01N23/00 ,  G01N37/00 ,  G01Q10/00 ,  G01Q60/38 ,  G11B5/00 ,  G11B9/00 ,  G11B9/14

    CPC分类号： G01Q70/06 ,  B82Y35/00 ,  G01Q60/38 ,  G11B5/00 ,  G11B9/14 ,  G11B9/1418 ,  B82Y10/00 ,  Y10S977/872

    摘要： A microfabricated microscope assembly including a piezoelectric bimorph cantilever arm mounted at one end to a first substrate. The free end of the canitlever arm has a tip mounted thereto for scanning a scanned surface mounted on a second substrate. The cantilever arm and the substrate are configured to carry out a predetermined write or read mode of operation, such as scanning tunneling microscopy or atomic force microscopy. The two substrates are spaced apart a fixed distance by spacer feet which project from one of the substrates and which have their ends fixed to ther surface of the other substrate by eutectic, aniodic, or adhesive bonding. An array of microfabricated microscope assemblies is formed using a plurality of individual assemblies. A number of different write/read modes of operation are accommodated, such as charge storage, molecular attachment, or magnetic domains. An array of piezoelectric cantilever arms having tips fixed to the free ends thereof and mounted to a substrate form are used to scan a scanned surface. The array is moved laterally with respect to the scanned surface using mechanical actuators as micropositioners for coarse positioning and using the piezoelectric cantilever arms for fine positioning.

    摘要翻译： 一种微加工显微镜组件，其包括一端安装在第一基板上的压电双压电晶片悬臂。 角色手臂的自由端具有安装在其上的尖端，用于扫描安装在第二基底上的扫描表面。 悬臂和衬底被配置为执行预定的写入或读取操作模式，例如扫描隧道显微镜或原子力显微镜。 两个基板通过间隔脚间隔一定距离，该间隔脚从一个基底突出，并且其端部通过共晶，非碘化或粘合粘合固定在另一个基底的其它表面上。 使用多个单独的组件形成微阵列显微镜组件阵列。 容纳许多不同的写入/读取操作模式，例如电荷存储，分子附着或磁畴。 使用具有固定到其自由端并安装到基板形式的顶端的压电悬臂的阵列来扫描扫描的表面。 使用机械致动器作为用于粗定位的微定位器并使用压电悬臂来进行精细定位，阵列相对于扫描表面横向移动。

    Multi-mode communication ingestible event markers and systems, and methods of using the same
    24.
    发明授权
    Multi-mode communication ingestible event markers and systems, and methods of using the same 有权
    多模式通信可摄取事件标记和系统及其使用方法

    公开(公告)号：US08258962B2

    公开(公告)日：2012-09-04

    申请号：US12398941

    申请日：2009-03-05

    申请人： Timothy Robertson ,  Mark J. Zdeblick

    发明人： Timothy Robertson ,  Mark J. Zdeblick

    IPC分类号： G08B23/00

    CPC分类号： H04B5/0062 ,  A61B5/0031 ,  A61B5/073 ,  A61B5/4833 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/6861 ,  A61B2562/08 ,  A61B2562/162 ,  G06K7/10297

    摘要： Aspects of the invention include multi-mode communication ingestible event marker devices. Ingestible event marker devices of the invention include an ingestible component comprising a conductive communication module and at least one additional non-conductive communication module. The non-conductive communication module may be integrated with the ingestible component or at least a portion or all of the non-conductive communication module may be associated with a packaging component of the ingestible event marker device. Additional aspects of the invention include systems that include the devices and one or more receivers, as well as methods of using the same.

    摘要翻译： 本发明的方面包括多模式通信可摄取事件标记装置。 本发明的可摄入事件标记装置包括可摄入组件，其包括导电通信模块和至少一个附加的非导电通信模块。 非导电通信模块可以与可摄取组件集成，或者非导电通信模块的至少一部分或全部可以与可摄入事件标记设备的包装组件相关联。 本发明的另外的方面包括包括装置和一个或多个接收器的系统，以及使用该装置的方法。

    System for Supply Chain Management
    25.
    发明申请
    System for Supply Chain Management 有权
    供应链管理系统

    公开(公告)号：US20120220838A1

    公开(公告)日：2012-08-30

    申请号：US13508327

    申请日：2010-11-04

    申请人： Mark J. Zdeblick

    发明人： Mark J. Zdeblick

    IPC分类号： A61B5/07

    CPC分类号： H04B5/0012 ,  A61B5/061 ,  G06K7/01 ,  G06Q10/06

    摘要： A system for tracking a product from origin to destination is disclosed. The system includes a probe that comprises two plates, a power source and a processor. The power source is controlled by the processor to produce an oscillating output at the plates. Using the oscillating voltage, the probe interrogates a device through capacitive coupling. The device includes a control unit, a memory unit, and first and second materials physically associated with the device for communication using capacitive coupling. Information associated with the device is transferred from the device to the probe through capacitive coupling between the first and second materials and the first and second plates, respectively.

    摘要翻译： 公开了一种从原产地到目的地跟踪产品的系统。 该系统包括一个包括两个板，一个电源和一个处理器的探头。 电源由处理器控制，以在板上产生振荡输出。 使用振荡电压，探头通过电容耦合来询问器件。 该装置包括控制单元，存储器单元以及物理上与用于使用电容耦合进行通信的装置相关联的第一和第二材料。 与装置相关的信息通过第一和第二材料与第一和第二板之间的电容耦合从装置传送到探针。

    Measuring conduction velocity using one or more satellite devices
    27.
    发明授权
    Measuring conduction velocity using one or more satellite devices 有权
    使用一个或多个卫星设备测量传导速度

    公开(公告)号：US07983751B2

    公开(公告)日：2011-07-19

    申请号：US12063097

    申请日：2006-08-09

    申请人： Mark J. Zdeblick ,  Timothy Robertson ,  George M. Savage

    发明人： Mark J. Zdeblick ,  Timothy Robertson ,  George M. Savage

    IPC分类号： A61N1/00

    CPC分类号： A61B5/04011

    摘要： A method for measuring the conduction velocity of a depolarization wave in a tissue employs a first satellite located within the tissue and a second that satellite is located within the tissue a distance away from the first satellite, e.g., by using the time of depolarization wave as reported from each satellite and the distance to determine velocity of the wave. Also provided are systems and kits that find use in accordance with the invention.

    摘要翻译： 用于测量组织中去极化波的传导速度的方法使用位于组织内的第一卫星，并且第二卫星位于组织内距离第一卫星一定距离，例如通过使用去极化波的时间作为 报道从每颗卫星和距离来确定波的速度。 还提供了根据本发明使用的系统和试剂盒。

    Electrical Angle Gauge
    28.
    发明申请
    Electrical Angle Gauge 审中-公开
    电子角度计

    公开(公告)号：US20110066057A1

    公开(公告)日：2011-03-17

    申请号：US12950818

    申请日：2010-11-19

    申请人： Mark J. Zdeblick

    发明人： Mark J. Zdeblick

    IPC分类号： A61N1/365 ,  A61B5/11 ,  A61B5/02

    CPC分类号： A61B5/0215 ,  A61B5/061 ,  A61B5/11 ,  A61B5/1126 ,  A61B5/6851 ,  A61B5/6852 ,  A61B5/6869 ,  A61B2562/04 ,  A61B2562/043 ,  A61M25/01 ,  A61M2025/0166 ,  A61N1/056 ,  A61N1/36514 ,  A61N1/36578

    摘要： Methods of using electrodes to obtain physiological location motion data are provided. Embodiments of the methods include producing an electrode from a broadcasting electrode that is proximal to the physiological location of interest and detecting a change in an induced electric potential at a receiving electrode to obtain the motion data of interest. Also provided are systems and components thereof, e.g., programming, for practicing methods according to embodiments of the invention.

    摘要翻译： 提供了使用电极获得生理位置运动数据的方法。 所述方法的实施例包括从广播电极产生电极，其接近于感兴趣的生理位置，并检测接收电极处的感应电位的变化以获得感兴趣的运动数据。 还提供了用于根据本发明的实施例的实践方法的系统及其组件，例如编程。

    Methods for Configuring Implantable Satellite Effectors
    29.
    发明申请
    Methods for Configuring Implantable Satellite Effectors 有权
    配置植入式卫星效应器的方法

    公开(公告)号：US20100114250A1

    公开(公告)日：2010-05-06

    申请号：US12624241

    申请日：2009-11-23

    申请人： Mark J. Zdeblick

    发明人： Mark J. Zdeblick

    IPC分类号： A61N1/08

    CPC分类号： A61N1/372 ,  A61B5/04011 ,  A61B5/0422 ,  A61N1/056 ,  A61N1/36185 ,  A61N1/368 ,  A61N1/3684 ,  A61N1/3686 ,  A61N1/37211 ,  A61N1/37276 ,  A61N1/37288 ,  A61N2001/0585

    摘要： Techniques for controlling one or more modular circuits (“satellites”) that are intended for placement in a subject's body. The one or more satellites are controlled by sending signals over a bus that includes first and second conduction paths. Also coupled to the bus in system embodiments is a device such as a pacemaker that provides power and includes control circuitry. Each satellite includes satellite circuitry and one or more effectors that interact with the tissue. The satellite circuitry is coupled to the bus, and thus interfaces the controller to the one or more effectors, which may function as actuators, sensors, or both. The effectors may be electrodes that are used to introduce analog electrical signals (e.g., one or more pacing pulses) into the tissue in the local areas where the electrodes are positioned (e.g., heart muscles) or to sense analog signals (e.g., a propagating depolarization signal) within the tissue.

    摘要翻译： 用于控制用于放置在受检者体内的一个或多个模块化电路（“卫星”）的技术。 通过在包括第一和第二导电路径的总线上发送信号来控制一个或多个卫星。 在系统实施例中还耦合到总线的是诸如提供电力并包括控制电路的起搏器的装置。 每个卫星包括卫星电路和与组织相互作用的一个或多个效应器。 卫星电路耦合到总线，并且因此使控制器与一个或多个效应器接合，这些效应器可以用作致动器，传感器或两者。 效应器可以是用于将模拟电信号（例如，一个或多个起搏脉冲）引入电极定位的局部区域（例如，心脏肌肉）中的组织中或用于感测模拟信号（例如，传播 去极化信号）。