公开(公告)号：US4568444A

公开(公告)日：1986-02-04

申请号：US724641

申请日：1985-04-18

申请人： Michihiro Nakamura ,  Makoto Yano ,  Hidehiko Ikeya ,  Hiroshi Tsurumi ,  Osamu Kusudo ,  Yoshito Hamamoto

发明人： Michihiro Nakamura ,  Makoto Yano ,  Hidehiko Ikeya ,  Hiroshi Tsurumi ,  Osamu Kusudo ,  Yoshito Hamamoto

IPC分类号： G01N27/401 ,  G01N27/30 ,  G01N27/403 ,  G01N27/50

CPC分类号： G01N27/4035

摘要： An apparatus for measuring the quantities of chemical substances contained in a solution to be assayed by using a chemical-substance sensitive sensor consists of a potentiometric electrode which responds selectively to chemical substances, and a liquid-junction type reference electrode including a tube, a porous thread member housed in the front end opening of the tube and having a pore capacity of 0.2 cc/g or more and at least the surface of which is hydrophilic, a silver-silver chloride wire is provided and housed in the tube so that at one end of the wire is in contact with the thread member and the wire which extends along the tube. The wire is connected to a connector at the other end opening of the tube, an electrical insulating resin fills said tube, at least at the front end portion thereof, for fixing both the silver-silver chloride wire and the thread member by contact therewith and for stopping said tube. An internal solution is retained by suction in said porous thread member. This apparatus is advantageously used for monitoring the living body and may be thermally sterilized.

摘要翻译： 用于测量通过使用化学物质敏感传感器测定的溶液中所含的化学物质的量的装置由选择性地对化学物质作出响应的电位电极和包括管的液体接合型参比电极，多孔 螺纹构件容纳在管的前端开口中，孔容量为0.2cc / g以上，至少其表面为亲水性，银 - 氯化银线被提供并容纳在管中，使得在一个 线的端部与螺纹构件和沿着管延伸的线接触。 导线连接到管的另一端开口处的连接器，电绝缘树脂至少在其前端部填充所述管，用于通过与其接触固定银 - 氯化银线和线构件， 用于停止所述管。 内部溶液通过吸力保持在所述多孔螺纹构件中。 该装置有利地用于监测生物体并且可以被热灭菌。

公开(公告)号：US08815078B2

公开(公告)日：2014-08-26

申请号：US13391746

申请日：2010-08-24

申请人： Akira Yamada ,  Michihiro Nakamura ,  Satoshi Mohri ,  Keiji Naruse

发明人： Akira Yamada ,  Michihiro Nakamura ,  Satoshi Mohri ,  Keiji Naruse

IPC分类号： G01N27/416

CPC分类号： G01N27/4167 ,  G01N27/414 ,  H01L2924/13073

摘要： Disclosed are a pH or concentration measuring device and a pH or concentration measuring method which enable measurement in the shortest possible time even in an object to be measured having low buffer capacity. Specifically disclosed are a pH or concentration measuring device and measuring method for measuring the pH or concentration of a sample solution that is an object to be measured, the device being provided with first and second sensors that each output a signal corresponding to the pH or concentration of a solution, an inspection tube that is provided with a first room in which the first sensor is disposed and a second room in which the second sensor is disposed, a feeding means that feeds a baseline solution into the inspection tube, and an injecting means which injects the sample solution into the first room of the inspection tube and brings the sample solution into contact with the first sensor, wherein a vibration means which vibrates the interface between the sample solution stored in the first room and the baseline solution is provided.

摘要翻译： 公开了一种pH或浓度测量装置和pH或浓度测量方法，即使在具有低缓冲容量的被测量物体中也能够在最短的时间内进行测量。 具体公开的是用于测量作为被测量对象物的样品溶液的pH或浓度的pH或浓度测量装置和测量方法，该装置设置有第一和第二传感器，每个传感器输出对应于pH或浓度的信号 解决方案的检查管，设置有设置有第一传感器的第一房间和设置有第二传感器的第二房间的检查管，将基线溶液供给到检查管中的供给单元，以及注入单元 其将样品溶液注入检查管的第一房间，并使样品溶液与第一传感器接触，其中提供振动装置，其振动存储在第一房间中的样品溶液与基线溶液之间的界面。

公开(公告)号：US07884956B2

公开(公告)日：2011-02-08

申请号：US11064929

申请日：2005-02-25

申请人： Michihiro Nakamura

发明人： Michihiro Nakamura

IPC分类号： G06F3/12 ,  H04N1/00

CPC分类号： H04N1/00204 ,  H04N1/00209 ,  H04N1/00212 ,  H04N1/32406 ,  H04N2201/0017

摘要： A network facsimile system is configured such that telephone numbers which a relay server can user are assigned to communication terminals. When a image is transmitted from the communication terminals to destinations outside the network facsimile system via the relaying server, the assigned telephone numbers are used as station signal numbers. When an image is transmitted to the relaying server from origins outside the network facsimile system, destination communication terminals are identified based on the telephone numbers assigned thereto and receiving telephone numbers. Then, the image received by the relaying server is transmitted to the identified communication terminals.

摘要翻译： 网络传真系统被配置为使得中继服务器可以将用户的电话号码分配给通信终端。 当通过中继服务器将图像从通信终端发送到网络传真系统外的目的地时，分配的电话号码被用作站信号号码。 当图像从网络传真系统外的起始传送到中继服务器时，基于分配给其的电话号码和接收电话号码来识别目的地通信终端。 然后，由中继服务器接收的图像被发送到所识别的通信终端。

公开(公告)号：US20100330582A1

公开(公告)日：2010-12-30

申请号：US12303870

申请日：2007-06-07

申请人： Michihiro Nakamura

发明人： Michihiro Nakamura

IPC分类号： G01N33/53 ,  C07F7/18

CPC分类号： G01N33/588 ,  B82Y15/00 ,  B82Y30/00 ,  C08G77/02 ,  C08G77/06 ,  C08G77/28 ,  G01N33/585 ,  Y10T428/2982 ,  Y10T436/101666 ,  Y10T436/109163

摘要： The present invention presents a silica particle containing at least one silica compound selected from a group consisting of mercapto-propyl-trimethoxysilane (MPS), mercapto-propyl-triethoxysilane (MPES), mercapto-propyl-methyldimethoxysilane (MPDMS), trimethoxy[2-(7-oxabicyclo[4.1.0]-hepto-3-yl)ethyl]silane(EpoPS), thiocyanatopropyltriethoxysilane (TCPS), and acryloxypropyltrimethoxysilane (AcPS), which can be provided and utilized as a label, a marker, or the like for qualitative test and quantitative test for such as prophylactic agent, therapeutic agent, diagnostic agent, diagnostic and therapeutic agent or the like in dental, medical and veterinary fields regardless of fields.

摘要翻译： 本发明提供了含有选自巯基丙基三甲氧基硅烷（MPS），巯基丙基三乙氧基硅烷（MPES），巯基丙基甲基二甲氧基硅烷（MPDMS），三甲氧基[2- （7-氧杂双环[4.1.0] - 庚-3-基）乙基]硅烷（EpoPS），硫氰酸丙基三乙氧基硅烷（TCPS）和丙烯酰氧基丙基三甲氧基硅烷（AcPS），其可以提供和用作标记，标记等 用于牙科，医学和兽医领域的诸如预防剂，治疗剂，诊断剂，诊断和治疗剂等的定性测试和定量测试，不论其领域如何。

公开(公告)号：US07616336B2

公开(公告)日：2009-11-10

申请号：US11064972

申请日：2005-02-25

申请人： Michihiro Nakamura

发明人： Michihiro Nakamura

IPC分类号： G06F3/12 ,  H04N1/00 ,  H04N1/32

CPC分类号： H04N1/324 ,  H04N1/00209 ,  H04N1/00212 ,  H04N1/32406 ,  H04N2201/0017 ,  H04N2201/0024

摘要： A network facsimile system including a relaying server and a communication terminal connected through a network. The relaying server has a facsimile communication system, an image data creating system, an information obtaining system, and a relaying server side data communication system. Further, the communication terminal includes a communication terminal side data communication system and an image data processing system. The relaying server includes a status setting system that sets an operational status of the network facsimile system to a receivable state where the communication terminal can receive the image through the relaying server when the communication terminal has become usable by a user of the communication terminal.

摘要翻译： 一种网络传真系统，包括中继服务器和通过网络连接的通信终端。 中继服务器具有传真通信系统，图像数据创建系统，信息获取系统和中继服务器端数据通信系统。 此外，通信终端包括通信终端侧数据通信系统和图像数据处理系统。 中继服务器包括状态设置系统，其将网络传真系统的操作状态设置为可通信状态，其中当通信终端已经被通信终端的用户使用时，通信终端可以通过中继服务器接收图像。

公开(公告)号：US06379910B1

公开(公告)日：2002-04-30

申请号：US09090410

申请日：1998-06-04

申请人： Michihiro Nakamura ,  Harutoshi Terasawa ,  Hiroyuki Okada ,  Hidenori Yukawa ,  Hidehiro Hosaka

发明人： Michihiro Nakamura ,  Harutoshi Terasawa ,  Hiroyuki Okada ,  Hidenori Yukawa ,  Hidehiro Hosaka

IPC分类号： C12Q158

CPC分类号： G01N33/54366 ,  G01N27/4167 ,  G01N2333/978

摘要： One end of a thin-tube type solid phase in which a receptor specific for a material or an organism to be measured which can induce a pH-change of substrate solution is immobilized is soaked in a sample solution and then taken out therefrom. The one end of the thin-tube type solid phase is disposed in a measurement cell and a sensing portion of a pH electrode disposed in the measurement cell is in the vicinity of the one end of the thin-tube type solid phase. The measurement cell and the thin-tube type solid phase are filled with a substrate solution so that a reaction takes place. Thereafter, the substrate solution in the thin-tube type solid phase is moved to the sensing portion by a solution feed pump. The output of the pH electrode at this timing is detected.

摘要翻译： 将固定有能够诱导底物溶液的pH变化的待测量材料或生物体的受体特异性的受体固定在细管型固相中的一端浸渍在样品溶液中，然后从其中取出。 细管型固相的一端设置在测量单元中，设置在测量单元中的pH电极的感测部分位于薄管型固相的一端附近。 测量单元和薄管型固相填充底物溶液，从而发生反应。 此后，通过溶液供给泵将细管型固相中的基板溶液移动到感测部。 在此时刻检测pH电极的输出。

公开(公告)号：US5969223A

公开(公告)日：1999-10-19

申请号：US109093

申请日：1998-07-02

申请人： Yuko Nagai ,  Tetsushi Sekiguchi ,  Tetsuya Makino ,  Michihiro Nakamura

发明人： Yuko Nagai ,  Tetsushi Sekiguchi ,  Tetsuya Makino ,  Michihiro Nakamura

IPC分类号： G01N33/00 ,  G01D18/00

CPC分类号： G01N33/0006

摘要： A gas sensor 1 has a catheter 3 to which a gas sensor body 4 and a signal guide member 5 for guiding a detection signal of the gas sensor body 4 are attached. The other end of the signal guide member 5 is connected to a connector 6. The gas sensor 1 is airtightly received in the reception body in the state where a connection terminal of the connector 6 is exposed to the outside. The reception body 2 is filled with a mixed gas containing a gas to be measured by a predetermined concentration. At the time of calibration, the connection terminal of the connector 6 is connected to a measurement amplifier while the reception body 2 is not opened and calibration is performed, and at the time of measurement, the reception body 2 is opened and the gas sensor 1 is taken out to perform ordinary measurement.

摘要翻译： 气体传感器1具有安装有用于引导气体传感器体4的检测信号的气体传感器主体4和信号引导部件5的导管3。 信号引导构件5的另一端连接到连接器6.气体传感器1在连接器6的连接端子暴露于外部的状态下气密地容纳在接收体中。 接收体2填充含有预定浓度的被测量气体的混合气体。 在校准时，连接器6的连接端子连接到测量放大器，同时接收体2未打开并进行校准，并且在测量时，接收体2打开，气体传感器1 被取出进行普通测量。

公开(公告)号：US5556760A

公开(公告)日：1996-09-17

申请号：US381000

申请日：1995-01-31

申请人： Michihiro Nakamura ,  Satomi Matsui ,  Keiko Oka ,  Hitoshi Tsuruta ,  Yoshihiro Koori ,  Takuji Kato ,  Shigeji Ito

发明人： Michihiro Nakamura ,  Satomi Matsui ,  Keiko Oka ,  Hitoshi Tsuruta ,  Yoshihiro Koori ,  Takuji Kato ,  Shigeji Ito

IPC分类号： G01N27/416 ,  A61B10/00 ,  C12M1/34 ,  C12Q1/00 ,  C12Q1/58 ,  A61B5/04

CPC分类号： A61B5/14539 ,  C12Q1/00 ,  C12Q1/58

摘要： A method for assaying an enzyme on a targeted solid body surface, including the steps of contacting an end opening of a thin tube with a targeted solid body surface to form a space between the targeted solid body surface and inner wall surface of the thin tube, supplying a substrate solution into the space to bring the substrate solution in contact with the targeted solid body surface, and determining a pH change of the substrate solution in the space by using a pH electrode; and an apparatus therefor.

摘要翻译： 一种用于测定目标实体表面上的酶的方法，包括以下步骤：使细管的端部开口与目标实体表面接触，以在目标实体表面和细管的内壁表面之间形成空间， 将基材溶液供给到所述空间中，使所述基材溶液与所述目标固体表面接触，并且使用pH电极确定所述空间中的所述基材溶液的pH变化; 及其装置。

公开(公告)号：US4641249A

公开(公告)日：1987-02-03

申请号：US622250

申请日：1984-06-19

申请人： Hidenori Gion ,  Kenji Kubota ,  Michihiro Nakamura ,  Makoto Yano

发明人： Hidenori Gion ,  Kenji Kubota ,  Michihiro Nakamura ,  Makoto Yano

IPC分类号： G01N27/414 ,  G01N27/14 ,  G01N27/46 ,  G06F15/42

CPC分类号： G01N27/4148

摘要： An ion activity monitoring device is disclosed, having a semi-conductor device including an ion-sensitive field-effect transistor, for detecting the activity of ions in a liquid medium of interest, and a temperature sensor, for detecting the temperature of the liquid medium of interest, a constant current circuit for supplying a drain current of a particular value to the transistor, and a processing circuit for calculating the concentration of the ions in the liquid medium of interest. The drain current is of a value satisfying the relationship of .vertline.Id/.beta..vertline..ltoreq.0.10 volt.sup.2, wherein Id represents the drain current and .beta. represents the channel characteristic value of the ion-sensitive field-effect transistor. A method for operating the transistor is also disclosed.

摘要翻译： 公开了一种离子活性监测装置，其具有包括用于检测感兴趣的液体介质中的离子的活性的离子敏感场效应晶体管的半导体器件和用于检测液体介质的温度的温度传感器 用于向晶体管提供特定值的漏极电流的恒流电路，以及用于计算感兴趣的液体介质中的离子浓度的处理电路。 漏极电流为满足| Id /β|≤0.10V2的关系的值，其中Id表示漏极电流，β表示离子敏感场效应晶体管的沟道特性值。 还公开了一种用于操作晶体管的方法。

公开(公告)号：US4474183A

公开(公告)日：1984-10-02

申请号：US567559

申请日：1984-01-03

申请人： Makotao Yano ,  Michihiro Nakamura

发明人： Makotao Yano ,  Michihiro Nakamura

IPC分类号： G01N27/414 ,  G01N27/30 ,  G01N27/40

CPC分类号： G01N27/4141 ,  Y10S977/796

摘要： A gas sensor with its photosensitivity allayed in which a hydrogen ion sensitive FET transducer having the structure of a gate-insulated field effect transistor and an Ag-AgCl reference electrode are housed inside a flexible tube in such a way that the gate part of said FET transducer and the reference electrode are located at the front end opening of the tube or an opening provided in the side wall of the tube; while the lead wires connected to the FET transducer and the reference electrode are extended along the tube, this tube is closed by filling an electrical insulation resin at least in the space of the part inside the tube wall housing the parts connecting the lead wires to the aforementioned FET transducer and to the reference electrode; further, a hydrophilic polymer containing an electrolyte is put around at least the gate part of said FET and part of the reference electrode, to envelop both of them; and whole of the surface of the aforementioned hydrophilic polymer and that of at least the part of the insulator tube housing the FET transducer are coated with a gas permeable membrane formed of a colored silicone rubber with a low optical transmittance.

摘要翻译： 一种具有光敏性的气体传感器，其中具有栅极绝缘场效应晶体管和Ag-AgCl参考电极的结构的氢离子敏感FET换能器容纳在柔性管内，使得所述FET的栅极部分 换能器和参考电极位于管的前端开口处或设置在管的侧壁中的开口; 当连接到FET换能器和参考电极的引线沿着管延伸时，该管通过至少在管壁内的部分空间中填充电绝缘树脂来封闭，该管壁将容纳连接引线的部分 上述FET换能器和参考电极; 此外，含有电解质的亲水性聚合物至少围绕所述FET的栅极部分和参考电极的一部分，以包围它们; 并且上述亲水性聚合物的整个表面以及容纳FET换能器的绝缘体管的至少一部分的表面涂覆有由具有低透光率的有色硅橡胶形成的透气膜。