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公开(公告)号：US20240135185A1
公开(公告)日：2024-04-25
申请号：US18167381
申请日：2023-02-10
Inventor： Shashanka Ubaru , Paz Fink Shustin , Lior Horesh , Vasileios Kalantzis , Haim Avron
IPC: G06N3/088 , G06N3/04 , G06N3/0455
CPC classification number: G06N3/088 , G06N3/0418 , G06N3/0455
Abstract: A method to determine data uncertainty is provided. The method receives a high dimensional data input and a corresponding data output. The method trains a variational autoencoder (VAE) with the high dimensional data input to learn a low dimensional latent space representation of the high dimensional data input. An encoder part of the VAE outputs a set of distributions of the high dimensional dataset in a latent space. The method samples new data samples in the latent space using the set of distributions outputs from the encoder part of the VAE. The method learns a polynomial chaos expansion to map the new data samples in the latent space to the corresponding data output to learn the set of distributions and their relation to perform estimation with high-dimensional dataset under uncertainty such as missing values by estimating the values using the set of distributions.
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公开(公告)号：US20240108272A1
公开(公告)日：2024-04-04
申请号：US18557965
申请日：2021-03-11
Applicant: ICHILOV TECH LTD. , RAMOT AT TEL AVIV UNIVERSITY LTD.
Inventor： Talma HENDLER , Mordekhay MEDVEDOVSKY , Tomer GAZIT , Evgeny TSIZIN-GOLDMAN , Alexander BRONSTEIN
CPC classification number: A61B5/372 , A61B5/256 , A61B5/271 , A61B5/291 , A61B5/4094 , A61B5/7203 , A61B2562/046
Abstract: Provided herein are methods for EEG monitoring of a patient, which includes: positioning an array comprising a plurality of EEG electrodes on the patient's head; recording, during a first time period, a first data set of EEG signals from a first set of spatial scalp locations; manipulating the array to record, during a second time period, a second data set of EEG signals from a second set of spatial locations including at least some spatial scalp locations that are different from the first set of spatial scalp locations; integrating the first and second data sets, thereby generating a combined data set with a higher spatial density; and processing the combined data set to determine EEG events.
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公开(公告)号：US11948093B2
公开(公告)日：2024-04-02
申请号：US17938131
申请日：2022-10-05
Applicant: International Business Machines Corporation , Trustees of Tufts College , Ramot at Tel-Aviv University Ltd.
Inventor： Lior Horesh , Elizabeth Newman , Misha E. Kilmer , Haim Avron
Abstract: Techniques for generating and managing, including simulating and training, deep tensor neural networks are presented. A deep tensor neural network comprises a graph of nodes connected via weighted edges. A network management component (NMC) extracts features from tensor-formatted input data based on tensor-formatted parameters. NMC evolves tensor-formatted input data based on a defined tensor-tensor layer evolution rule, the network generating output data based on evolution of the tensor-formatted input data. The network is activated by non-linear activation functions, wherein the weighted edges and non-linear activation functions operate, based on tensor-tensor functions, to evolve tensor-formatted input data. NMC trains the network based on tensor-formatted training data, comparing output training data output from the network to simulated output data, based on a defined loss function, to determine an update. NMC updates the network, including weight and bias parameters, based on the update, by application of tensor-tensor operations.
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公开(公告)号：US11933866B2
公开(公告)日：2024-03-19
申请号：US16992160
申请日：2020-08-13
Applicant: Tel HaShomer Medical Research Infrastructure and Services Ltd. , Ramot at Tel-Aviv University Ltd.
Inventor： Yael Mardor , Leor Zach , David Guez , David Last , Dianne Daniels Elmakias
IPC: G01R33/28 , A61B5/00 , A61B5/055 , G01R33/48 , G01R33/56 , G06T7/00 , G16H30/40 , G16H40/40 , G16H40/63 , A61K31/166 , A61K31/555 , A61K31/7068
CPC classification number: G01R33/281 , A61B5/0042 , A61B5/055 , A61B5/4842 , A61B5/4848 , A61B5/7275 , G01R33/4806 , G01R33/5601 , G01R33/5608 , G06T7/0016 , G16H30/40 , G16H40/40 , G16H40/63 , A61B2576/026 , A61K31/166 , A61K31/555 , A61K31/7068 , A61K2300/00 , G06T2207/10096 , G06T2207/30016 , G06T2207/30096
Abstract: Apparatus for operating MRI is disclosed. The apparatus comprises: a control for operating an MRI scanner to carry out an MRI scan; an input for receiving first and second MRI scans respectively at the beginning and end of a predetermined time interval post contrast administration; a subtraction map former for forming a subtraction map from the first and the second MRI scans by analyzing the scans to distinguish between a population in which contrast clearance from the tissue is slower than contrast accumulation, and a population in which clearance is faster than accumulation; and an output to provide an indication of distribution of the populations. The control is configured to carry out the first scan at least five minutes and no more than twenty minutes post contrast administration and to carry out the second scan such that the predetermined time period is at least twenty minutes.
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公开(公告)号：US11931429B2
公开(公告)日：2024-03-19
申请号：US17451536
申请日：2021-10-20
Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
Inventor： Doron Shabat , Ronit Satchi-Fainaro , Nir Hananya , Ori Green , Tal Eilon
IPC: A61K49/00 , C07D321/00 , C07F5/02 , C07F5/04 , C07F7/18 , C07F9/12 , C07F9/655 , C07H15/203 , C07H15/26 , C09B11/24 , C09B23/01 , C09B23/04 , C09B23/08 , C09K11/06
CPC classification number: A61K49/0052 , C07D321/00 , C07F5/025 , C07F5/04 , C07F7/1804 , C07F9/12 , C07F9/65512 , C07H15/203 , C07H15/26 , C09B11/24 , C09B23/0066 , C09B23/04 , C09B23/083 , C09K11/06 , C09K2211/1018
Abstract: The present invention provides dioxetane-based chemiluminescence probes, more specifically fluorophore-tethered dioxetane-based chemiluminescence probes and compositions thereof. The chemiluminescence probes disclosed are useful for both diagnostics and in vivo imaging.
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Patent Agency Ranking
公开(公告)号：US20240067966A1
公开(公告)日：2024-02-29
申请号：US18310044
申请日：2023-05-01
Applicant: Tel Hashomer Medical Research Infrastructure and Services Ltd. , Ramot At Tel-Aviv University Ltd.
Inventor： Yael HABERMAN ZIV , Katya Elinoy SOSNOVSKI , Tzipi BRAUN
IPC: C12N15/113 , A61K45/06 , A61P29/00
CPC classification number: C12N15/113 , A61K45/06 , A61P29/00 , G01N33/6893
Abstract: The present invention provides methods of treating or preventing chronic intestinal inflammation and/or inflammatory bowel disease (IBD) comprising administering GATA6-AS1 lncRNA to a patient in need thereof.
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公开(公告)号：US11911138B2
公开(公告)日：2024-02-27
申请号：US16272616
申请日：2019-02-11
Applicant: Tel HaShomer Medical Research Infrastructure and Services Ltd. , RAMOT AT TEL AVIV UNIVERSITY LTD.
Inventor： Genady Kostenich , Arie Orenstein , Michael Belkin
CPC classification number: A61B5/0261 , A61B1/041 , A61B3/12 , A61B3/1241 , A61B5/0075 , A61B5/489 , A61B5/0077 , A61B5/0084 , F04C2270/041
Abstract: Disclosed are methods and devices useful for imaging blood-containing tissue, for example for angiography, especially retinal angiography, whereby an image is generated by dividing pixels of an image acquired at some wavelength range by corresponding pixels of an image acquired at a different wavelength range. In some embodiments, a first wavelength range includes predominantly light having wavelengths between about 400 nm and about 620 nm and a second wavelength range includes predominantly light having wavelengths between about 620 nm and about 800 nm.
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公开(公告)号：US11841410B2
公开(公告)日：2023-12-12
申请号：US17585812
申请日：2022-01-27
Inventor： Noam Ben-Eliezer , Noam Omer , Meirav Galun
CPC classification number: G01R33/50 , A61B5/055 , G01R33/5602 , G01R33/5608
Abstract: Method for mapping the transverse relaxation times (T2) in a magnetic resonance imaging (MRI) scan defined over a plurality of pixels, where each pixel is associated with a multicomponent T2 (mcT2) signal, comprises: accessing a computer readable medium storing an mcT2 dictionary having a set of synthetic mcT2 signals, and selecting a subset of synthetic mcT2 signals for which correlations between the synthetic mcT2 signals and pixels in the MRI scan are highest among the set. For each of at least a portion of the pixels, a respective mcT2 scan signal is fitted to the subset to provide, a plurality of T2 values for the pixel. A T2 map of the MRI scan is generated based on the T2 values.
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公开(公告)号：US20230390287A1
公开(公告)日：2023-12-07
申请号：US18235392
申请日：2023-08-18
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Ronit SATCHI-FAINARO , Helena FLORINDO , Rita GUEDES , Rita ACÚRCIO
IPC: A61K31/506 , A61K31/428 , A61K31/351 , A61K31/135 , A61K31/44
CPC classification number: A61K31/506 , A61K31/428 , A61K31/44 , A61K31/135 , A61K31/351
Abstract: Compounds (small molecules) capable of interfering with an interaction between PD-1 and PD-L1, and thereby are usable in treating cancer and/or in increasing T-cell function and/or in treating a medical condition associate with PD1, PD-L1 and/or T-cell function on cells, pharmaceutical compositions and kits comprising same and uses thereof, are provided.
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公开(公告)号：US20230375462A1
公开(公告)日：2023-11-23
申请号：US18198354
申请日：2023-05-17
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Raja GIRYES , Shay Avraham ELMALEM
CPC classification number: G01N21/21 , G02B5/0263 , G02B27/288 , H04N25/40
Abstract: A system for polarization imaging comprises an optical diffuser characterized by a point spread function (PSF), an image sensor, a spatially multiplexed polarization filter between the optical diffuser and the image sensor, and an image processor. The image processor receives signals from the image sensor and reconstructs, based on the PSF, a separate image for each polarization direction formed on the polarization filter.
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